GB1115417A - Compositions containing raubasine and a new method of using raubasine - Google Patents
Compositions containing raubasine and a new method of using raubasineInfo
- Publication number
- GB1115417A GB1115417A GB6396/67A GB639667A GB1115417A GB 1115417 A GB1115417 A GB 1115417A GB 6396/67 A GB6396/67 A GB 6396/67A GB 639667 A GB639667 A GB 639667A GB 1115417 A GB1115417 A GB 1115417A
- Authority
- GB
- United Kingdom
- Prior art keywords
- raubasine
- admixture
- salt
- liquid
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GRTOGORTSDXSFK-XJTZBENFSA-N ajmalicine Chemical compound C1=CC=C2C(CCN3C[C@@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 GRTOGORTSDXSFK-XJTZBENFSA-N 0.000 title abstract 5
- ZLQMRLSBXKQKMG-UHFFFAOYSA-N rauniticine Natural products COC(=O)C1=CC2CC3N(CCc4c3[nH]c5ccccc45)CC2C(C)O1 ZLQMRLSBXKQKMG-UHFFFAOYSA-N 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- CZJDUZOWQVAEEV-XIEZEKGWSA-N (+)-19-epi-Ajmalicine Natural products O=C(OC)C=1[C@@H]2[C@@H]([C@@H](C)OC=1)C[N+]1[C@H](c3[nH]c4c(c3CC1)cccc4)C2 CZJDUZOWQVAEEV-XIEZEKGWSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 206010040943 Skin Ulcer Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- BLGXFZZNTVWLAY-CCZXDCJGSA-N Yohimbine Natural products C1=CC=C2C(CCN3C[C@@H]4CC[C@@H](O)[C@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-CCZXDCJGSA-N 0.000 abstract 1
- 229940007897 ajmalicine Drugs 0.000 abstract 1
- BLGXFZZNTVWLAY-UHFFFAOYSA-N beta-Yohimbin Natural products C1=CC=C2C(CCN3CC4CCC(O)C(C4CC33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-UHFFFAOYSA-N 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- -1 citrate or tartrate Chemical compound 0.000 abstract 1
- 229940012017 ethylenediamine Drugs 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000012439 solid excipient Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
- 210000003462 vein Anatomy 0.000 abstract 1
- 208000037997 venous disease Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 229960000317 yohimbine Drugs 0.000 abstract 1
- AADVZSXPNRLYLV-UHFFFAOYSA-N yohimbine carboxylic acid Natural products C1=CC=C2C(CCN3CC4CCC(C(C4CC33)C(O)=O)O)=C3NC2=C1 AADVZSXPNRLYLV-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6396/67A GB1115417A (en) | 1967-02-10 | 1967-02-10 | Compositions containing raubasine and a new method of using raubasine |
| DE19681692039 DE1692039A1 (de) | 1967-02-10 | 1968-01-26 | Neue Verwendungsarten des Alkaloids Raubasin sowie entsprechende Zubereitungen |
| US700875*A US3564094A (en) | 1967-02-10 | 1968-01-26 | Method of treating venous diseases |
| BE710562D BE710562A (enrdf_load_stackoverflow) | 1967-02-10 | 1968-02-09 | |
| NL686801841A NL142593B (nl) | 1967-02-10 | 1968-02-09 | Werkwijze voor de bereiding van raubasine bevattende samenstellingen en doseringseenheden bereid volgens deze werkwijze. |
| FR139329A FR7342M (enrdf_load_stackoverflow) | 1967-02-10 | 1968-02-09 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6396/67A GB1115417A (en) | 1967-02-10 | 1967-02-10 | Compositions containing raubasine and a new method of using raubasine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1115417A true GB1115417A (en) | 1968-05-29 |
Family
ID=9813753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6396/67A Expired GB1115417A (en) | 1967-02-10 | 1967-02-10 | Compositions containing raubasine and a new method of using raubasine |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3564094A (enrdf_load_stackoverflow) |
| BE (1) | BE710562A (enrdf_load_stackoverflow) |
| DE (1) | DE1692039A1 (enrdf_load_stackoverflow) |
| FR (1) | FR7342M (enrdf_load_stackoverflow) |
| GB (1) | GB1115417A (enrdf_load_stackoverflow) |
| NL (1) | NL142593B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2092608A1 (enrdf_load_stackoverflow) * | 1970-06-01 | 1972-01-28 | Roussel Uclaf |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2671727B1 (fr) * | 1991-01-18 | 1994-04-29 | Nawrocki Thadee | Utilisation de la raubasine pour traiter un mauvais metabolisme de fer. |
-
1967
- 1967-02-10 GB GB6396/67A patent/GB1115417A/en not_active Expired
-
1968
- 1968-01-26 US US700875*A patent/US3564094A/en not_active Expired - Lifetime
- 1968-01-26 DE DE19681692039 patent/DE1692039A1/de active Pending
- 1968-02-09 BE BE710562D patent/BE710562A/xx unknown
- 1968-02-09 NL NL686801841A patent/NL142593B/xx unknown
- 1968-02-09 FR FR139329A patent/FR7342M/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2092608A1 (enrdf_load_stackoverflow) * | 1970-06-01 | 1972-01-28 | Roussel Uclaf |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1692039A1 (de) | 1971-07-08 |
| NL6801841A (enrdf_load_stackoverflow) | 1968-08-12 |
| NL142593B (nl) | 1974-07-15 |
| FR7342M (enrdf_load_stackoverflow) | 1969-10-13 |
| BE710562A (enrdf_load_stackoverflow) | 1968-08-09 |
| US3564094A (en) | 1971-02-16 |
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