GB1111891A - Process for producing derivatives of nucleic acid - Google Patents
Process for producing derivatives of nucleic acidInfo
- Publication number
- GB1111891A GB1111891A GB523966A GB523966A GB1111891A GB 1111891 A GB1111891 A GB 1111891A GB 523966 A GB523966 A GB 523966A GB 523966 A GB523966 A GB 523966A GB 1111891 A GB1111891 A GB 1111891A
- Authority
- GB
- United Kingdom
- Prior art keywords
- metal ions
- fermentation
- derivatives
- phosphates
- tri
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Derivatives of nucleic acids are produced by fermentation in the presence of 1-200 mg. of iron, 10 m g-15 mg. of manganese, 0.5-30 mg. of calcium, and 1-1000 m g. of zinc bivalent metal ions, each amount being per litre of fermentation medium. The derivatives specified are 51-inosinic acid, 51-guanylic acid, guanosine di- and tri-phosphates, 51-adenylic acid, and adenosine di- and tri-phosphates. Specified micro-organisms are Brevibacterium ammoniagenes, Micrococcus sodonensis, and Aspergillus sojae. The metal ions are either added in the form of their sulphate or hydrochloride, or are present as impurities in other components of the fermentation medium. The fermentation is carried out under aerobic conditions, at 20 DEG to 40 DEG C., and with a pH of 5 to 9. The examples include comparative tests using only three of the metal ions in the suitable concentrations, and also tests using amounts of Mn2+ which are outside the given limits.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP705665 | 1965-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1111891A true GB1111891A (en) | 1968-05-01 |
Family
ID=11655391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB523966A Expired GB1111891A (en) | 1965-02-10 | 1966-02-07 | Process for producing derivatives of nucleic acid |
Country Status (3)
| Country | Link |
|---|---|
| DE (3) | DE1298072B (en) |
| FR (1) | FR1554572A (en) |
| GB (1) | GB1111891A (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB979141A (en) * | 1960-11-11 | 1965-01-01 | Kyowa Hakko Kogyo Kk | A method for manufacturing inosinic acid by fermentation |
| FR1372054A (en) * | 1963-08-07 | 1964-09-11 | Takeda Chemical Industries Ltd | Process for the preparation of purine derivatives |
-
1966
- 1966-02-07 GB GB523966A patent/GB1111891A/en not_active Expired
- 1966-02-10 DE DE1966K0064407 patent/DE1298072B/en active Pending
- 1966-02-10 FR FR1554572D patent/FR1554572A/fr not_active Expired
- 1966-02-10 DE DE1966K0058379 patent/DE1300895B/en active Pending
- 1966-02-10 DE DE1966K0064406 patent/DE1300896B/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR1554572A (en) | 1969-01-24 |
| DE1300896B (en) | 1969-08-14 |
| DE1300895B (en) | 1969-08-14 |
| DE1298072B (en) | 1969-06-26 |
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