GB1108950A - Alkoxysulphamyl-anthranilic acids and their manufacture and use - Google Patents
Alkoxysulphamyl-anthranilic acids and their manufacture and useInfo
- Publication number
- GB1108950A GB1108950A GB29374/65A GB2937465A GB1108950A GB 1108950 A GB1108950 A GB 1108950A GB 29374/65 A GB29374/65 A GB 29374/65A GB 2937465 A GB2937465 A GB 2937465A GB 1108950 A GB1108950 A GB 1108950A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- formula
- alkyl
- physiologically tolerable
- hydroxyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- WPVYIIURTFSWCJ-UHFFFAOYSA-N 4-chloro-2-fluoro-5-(methoxysulfamoyl)benzoic acid Chemical compound FC1=C(C(=O)O)C=C(C(=C1)Cl)S(NOC)(=O)=O WPVYIIURTFSWCJ-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- -1 cyclic secondary amine Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- DDRPCXLAQZKBJP-UHFFFAOYSA-N furfurylamine Chemical compound NCC1=CC=CO1 DDRPCXLAQZKBJP-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229910052727 yttrium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF43416A DE1220435B (de) | 1964-07-11 | 1964-07-11 | Verfahren zur Herstellung diuretisch und saluretisch wirksamer Alkoxysulfamyl-anthranilsaeuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1108950A true GB1108950A (en) | 1968-04-10 |
Family
ID=7099544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29374/65A Expired GB1108950A (en) | 1964-07-11 | 1965-07-12 | Alkoxysulphamyl-anthranilic acids and their manufacture and use |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3351589A (cg-RX-API-DMAC7.html) |
| AT (1) | AT252905B (cg-RX-API-DMAC7.html) |
| BE (1) | BE666766A (cg-RX-API-DMAC7.html) |
| BR (1) | BR6571108D0 (cg-RX-API-DMAC7.html) |
| CH (1) | CH467256A (cg-RX-API-DMAC7.html) |
| DE (1) | DE1220435B (cg-RX-API-DMAC7.html) |
| DK (1) | DK109335C (cg-RX-API-DMAC7.html) |
| FI (1) | FI43879B (cg-RX-API-DMAC7.html) |
| FR (1) | FR4861M (cg-RX-API-DMAC7.html) |
| GB (1) | GB1108950A (cg-RX-API-DMAC7.html) |
| IL (1) | IL23924A (cg-RX-API-DMAC7.html) |
| NL (1) | NL139663B (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017070084A1 (en) * | 2015-10-19 | 2017-04-27 | Cardioxyl Pharmaceuticals, Inc. | N-hydroxylsulfonamide derivatives as nitroxyl donors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1122541B (de) * | 1959-12-28 | 1962-01-25 | Hoechst Ag | Verfahren zur Herstellung von Sulfamyl-anthranilsaeuren |
-
0
- BE BE666766D patent/BE666766A/xx unknown
-
1964
- 1964-07-11 DE DEF43416A patent/DE1220435B/de active Pending
-
1965
- 1965-07-06 NL NL656508664A patent/NL139663B/xx unknown
- 1965-07-06 FI FI1596/65A patent/FI43879B/fi active
- 1965-07-07 US US470231A patent/US3351589A/en not_active Expired - Lifetime
- 1965-07-08 CH CH961865A patent/CH467256A/de unknown
- 1965-07-09 IL IL23924A patent/IL23924A/en unknown
- 1965-07-09 AT AT625765A patent/AT252905B/de active
- 1965-07-09 BR BR171108/65A patent/BR6571108D0/pt unknown
- 1965-07-09 DK DK352765AA patent/DK109335C/da active
- 1965-07-12 GB GB29374/65A patent/GB1108950A/en not_active Expired
- 1965-10-09 FR FR34379A patent/FR4861M/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017070084A1 (en) * | 2015-10-19 | 2017-04-27 | Cardioxyl Pharmaceuticals, Inc. | N-hydroxylsulfonamide derivatives as nitroxyl donors |
| CN108368038A (zh) * | 2015-10-19 | 2018-08-03 | 卡尔迪奥克斯尔制药公司 | 作为硝酰基供体的n-羟基磺酰胺衍生物 |
| JP2018537419A (ja) * | 2015-10-19 | 2018-12-20 | カルディオキシル ファーマシューティカルズ，インク． | ニトロキシルドナーとしてのｎ−ヒドロキシルスルホンアミド誘導体 |
| US10730828B2 (en) | 2015-10-19 | 2020-08-04 | Cardioxyl Pharmaceuticals, Inc. | N-hydroxylsulfonamide derivatives as nitroxyl donors |
Also Published As
| Publication number | Publication date |
|---|---|
| DK109335C (da) | 1968-04-16 |
| BE666766A (cg-RX-API-DMAC7.html) | |
| IL23924A (en) | 1969-01-29 |
| FI43879B (cg-RX-API-DMAC7.html) | 1971-03-31 |
| FR4861M (cg-RX-API-DMAC7.html) | 1967-02-27 |
| DE1220435B (de) | 1966-07-07 |
| AT252905B (de) | 1967-03-10 |
| NL139663B (nl) | 1973-09-17 |
| US3351589A (en) | 1967-11-07 |
| BR6571108D0 (pt) | 1973-08-02 |
| CH467256A (de) | 1969-01-15 |
| NL6508664A (cg-RX-API-DMAC7.html) | 1966-01-12 |
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