GB1106742A - New piperidine derivatives and the homologues thereof and process for their production - Google Patents
New piperidine derivatives and the homologues thereof and process for their productionInfo
- Publication number
- GB1106742A GB1106742A GB965565A GB965565A GB1106742A GB 1106742 A GB1106742 A GB 1106742A GB 965565 A GB965565 A GB 965565A GB 965565 A GB965565 A GB 965565A GB 1106742 A GB1106742 A GB 1106742A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fluorophenyl
- ethylenedioxy
- piperidine
- oxo
- butyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003053 piperidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- -1 alkyl radical Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 3
- VRJHQPZVIGNGMX-UHFFFAOYSA-N 4-piperidinone Chemical class O=C1CCNCC1 VRJHQPZVIGNGMX-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- BQOLKFJNJCOALF-UHFFFAOYSA-N piperidin-1-ium-4,4-diol;chloride Chemical compound Cl.OC1(O)CCNCC1 BQOLKFJNJCOALF-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VKIAPDHOXHTRCD-UHFFFAOYSA-N 2-(3-chlorobutyl)-2-(4-fluorophenyl)-4-methyl-1,3-dioxane Chemical compound FC1=CC=C(C=C1)C1(OCCC(O1)C)CCC(C)Cl VKIAPDHOXHTRCD-UHFFFAOYSA-N 0.000 abstract 1
- FXFDJSQOCVDXBX-UHFFFAOYSA-N 2-(3-chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane Chemical compound C1=CC(F)=CC=C1C1(CCCCl)OCCO1 FXFDJSQOCVDXBX-UHFFFAOYSA-N 0.000 abstract 1
- ONHQQEBZVXXMRC-UHFFFAOYSA-N 4,4-dimethoxypiperidine Chemical compound COC1(OC)CCNCC1 ONHQQEBZVXXMRC-UHFFFAOYSA-N 0.000 abstract 1
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- PYLWMHQQBFSUBP-UHFFFAOYSA-N monofluorobenzene Chemical compound FC1=CC=CC=C1 PYLWMHQQBFSUBP-UHFFFAOYSA-N 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D227/00—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
- C07D227/02—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D227/06—Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00 with only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Labeling Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH299464A CH437285A (de) | 1964-03-09 | 1964-03-09 | Verfahren zur Herstellung von neuen Pyrrolidin-, Piperidin- und Azepinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1106742A true GB1106742A (en) | 1968-03-20 |
Family
ID=4246253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB965565A Expired GB1106742A (en) | 1964-03-09 | 1965-03-08 | New piperidine derivatives and the homologues thereof and process for their production |
Country Status (14)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3484446A (en) * | 1967-01-16 | 1969-12-16 | Aldrich Chem Co Inc | 1-(3-(4-fluorobenzoyl)propyl) - and 1 - (1,1-ethylenedioxy - 1 - (4 - fluorophenyl)-4-butyl)-4-piperidyl carbamates |
| US3790525A (en) * | 1972-01-21 | 1974-02-05 | Sankyo Co | 4-piperidone ketal derivatives,their preparation and their use as stabilizers |
| JPS5420977B2 (enrdf_load_stackoverflow) * | 1972-10-26 | 1979-07-26 | ||
| US3940401A (en) | 1973-03-01 | 1976-02-24 | Sankyo Company Limited | 4,4-(O-phenylenedioxy)-2,2,6,6-tetramethyl piperidine |
| FR2845874B1 (fr) | 2002-10-21 | 2004-12-17 | Techpack Int | Emballage distributeur de produit en forme de stick a double paroi |
-
1964
- 1964-03-09 CH CH299464A patent/CH437285A/de unknown
-
1965
- 1965-03-04 FI FI53065A patent/FI44396C/fi active
- 1965-03-08 GB GB965565A patent/GB1106742A/en not_active Expired
- 1965-03-08 IL IL2311765A patent/IL23117A/xx unknown
- 1965-03-08 DE DE1965G0043026 patent/DE1545890A1/de active Pending
- 1965-03-08 NO NO15711265A patent/NO117179B/no unknown
- 1965-03-08 BE BE660763D patent/BE660763A/xx unknown
- 1965-03-08 NL NL6502929A patent/NL6502929A/xx unknown
- 1965-03-08 ES ES0310250A patent/ES310250A1/es not_active Expired
- 1965-03-08 AT AT202465A patent/AT251581B/de active
- 1965-03-08 DK DK119165A patent/DK107095C/da active
- 1965-03-08 SE SE300465A patent/SE326447B/xx unknown
- 1965-03-08 BR BR16766165A patent/BR6567661D0/pt unknown
- 1965-03-09 FR FR8427A patent/FR1441524A/fr not_active Expired
- 1965-06-08 FR FR19826A patent/FR4425M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE326447B (enrdf_load_stackoverflow) | 1970-07-27 |
| DK107095C (da) | 1967-04-24 |
| AT251581B (de) | 1967-01-10 |
| FR4425M (enrdf_load_stackoverflow) | 1966-10-17 |
| ES310250A1 (es) | 1965-12-16 |
| NO117179B (enrdf_load_stackoverflow) | 1969-07-14 |
| DE1545890A1 (de) | 1969-12-11 |
| NL6502929A (enrdf_load_stackoverflow) | 1965-09-10 |
| FI44396C (fi) | 1971-11-10 |
| BR6567661D0 (pt) | 1973-08-02 |
| CH437285A (de) | 1967-06-15 |
| BE660763A (enrdf_load_stackoverflow) | 1965-09-08 |
| FI44396B (enrdf_load_stackoverflow) | 1971-08-02 |
| FR1441524A (fr) | 1966-06-10 |
| IL23117A (en) | 1969-01-29 |
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