GB1106057A - Novel benzofuran derivatives and the manufacture thereof - Google Patents
Novel benzofuran derivatives and the manufacture thereofInfo
- Publication number
- GB1106057A GB1106057A GB19823/65A GB1982365A GB1106057A GB 1106057 A GB1106057 A GB 1106057A GB 19823/65 A GB19823/65 A GB 19823/65A GB 1982365 A GB1982365 A GB 1982365A GB 1106057 A GB1106057 A GB 1106057A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dimethyl
- prepared
- benzofuran
- compounds
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001907 coumarones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 abstract 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 150000003944 halohydrins Chemical class 0.000 abstract 2
- IGXOMTVOOXTCKI-UHFFFAOYSA-N 1-(5,6-dimethyl-1-benzofuran-2-yl)ethanone Chemical compound CC1=C(C)C=C2OC(C(=O)C)=CC2=C1 IGXOMTVOOXTCKI-UHFFFAOYSA-N 0.000 abstract 1
- HGKFMPRYPNPXGN-UHFFFAOYSA-N 2-chloro-1-(5,6-dimethyl-1-benzofuran-2-yl)ethanone Chemical compound ClCC(=O)C=1OC2=C(C1)C=C(C(=C2)C)C HGKFMPRYPNPXGN-UHFFFAOYSA-N 0.000 abstract 1
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- BULLHNJGPPOUOX-UHFFFAOYSA-N chloroacetone Chemical compound CC(=O)CCl BULLHNJGPPOUOX-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005283 haloketone group Chemical group 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19823/65A GB1106057A (en) | 1965-05-11 | 1965-05-11 | Novel benzofuran derivatives and the manufacture thereof |
| CH1749768A CH498109A (de) | 1965-05-11 | 1966-04-27 | Verfahren zur Herstellung von Benzofuranderivaten |
| CH67270A CH513146A (de) | 1965-05-11 | 1966-04-27 | Verfahren zur Herstellung von Benzofuranderivaten |
| CH610666A CH468371A (de) | 1965-05-11 | 1966-04-27 | Verfahren zur Herstellung von Benzofuranderivaten |
| IL25650A IL25650A (en) | 1965-05-11 | 1966-04-28 | Benzofuran derivatives and process for the manufacture thereof |
| DE19661543653 DE1543653C3 (de) | 1965-05-11 | 1966-04-29 | Basisch substituierte Benzofuranderivate und deren pharmazeutisch verträgliche Säureadditionssalze sowie Verfahren zu deren Herstellung und Arzneimittel mit einem Gehalt dieser Verbindungen |
| FR60694A FR1479002A (fr) | 1965-05-11 | 1966-05-07 | Procédé pour la préparation de dérivés de benzofurane |
| FR60695A FR6011M (cs) | 1965-05-11 | 1966-05-07 | |
| BR179335/66A BR6679335D0 (pt) | 1965-05-11 | 1966-05-09 | Processo para a preparacao de derivados de renzofurano |
| BE680737D BE680737A (cs) | 1965-05-11 | 1966-05-09 | |
| ES0326559A ES326559A1 (es) | 1965-05-11 | 1966-05-10 | Procedimiento para la sintesis de derivados de benzofurano. |
| NO162956A NO120270B (cs) | 1965-05-11 | 1966-05-10 | |
| FI661245A FI45329C (fi) | 1965-05-11 | 1966-05-11 | Tapa valmistaa terapeuttisesti vaikuttavia bentsofuraanijohdannaisia. |
| SE06456/66A SE326196B (cs) | 1965-05-11 | 1966-05-11 | |
| DK241366AA DK123769B (da) | 1965-05-11 | 1966-05-11 | Analogifremgangsmåde til fremstilling af 2-(2-alkylamino-1-hydroxy-ethyl)-benzofuranderivater eller syreadditionssalte deraf. |
| NL666606441A NL153541B (nl) | 1965-05-11 | 1966-05-11 | Werkwijze voor de bereiding van preparaten met beta-adrenergische blokkeerwerking, alsmede werkwijze voor de bereiding van daarvoor geschikte benzofuranderivaten. |
| US010645A US3929836A (en) | 1965-05-11 | 1970-02-11 | 2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB19823/65A GB1106057A (en) | 1965-05-11 | 1965-05-11 | Novel benzofuran derivatives and the manufacture thereof |
| GB5320865 | 1965-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1106057A true GB1106057A (en) | 1968-03-13 |
Family
ID=26254274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19823/65A Expired GB1106057A (en) | 1965-05-11 | 1965-05-11 | Novel benzofuran derivatives and the manufacture thereof |
Country Status (12)
| Country | Link |
|---|---|
| BE (1) | BE680737A (cs) |
| BR (1) | BR6679335D0 (cs) |
| CH (3) | CH513146A (cs) |
| DK (1) | DK123769B (cs) |
| ES (1) | ES326559A1 (cs) |
| FI (1) | FI45329C (cs) |
| FR (1) | FR6011M (cs) |
| GB (1) | GB1106057A (cs) |
| IL (1) | IL25650A (cs) |
| NL (1) | NL153541B (cs) |
| NO (1) | NO120270B (cs) |
| SE (1) | SE326196B (cs) |
-
1965
- 1965-05-11 GB GB19823/65A patent/GB1106057A/en not_active Expired
-
1966
- 1966-04-27 CH CH67270A patent/CH513146A/de not_active IP Right Cessation
- 1966-04-27 CH CH1749768A patent/CH498109A/de not_active IP Right Cessation
- 1966-04-27 CH CH610666A patent/CH468371A/de unknown
- 1966-04-28 IL IL25650A patent/IL25650A/xx unknown
- 1966-05-07 FR FR60695A patent/FR6011M/fr not_active Expired
- 1966-05-09 BE BE680737D patent/BE680737A/xx not_active IP Right Cessation
- 1966-05-09 BR BR179335/66A patent/BR6679335D0/pt unknown
- 1966-05-10 ES ES0326559A patent/ES326559A1/es not_active Expired
- 1966-05-10 NO NO162956A patent/NO120270B/no unknown
- 1966-05-11 FI FI661245A patent/FI45329C/fi active
- 1966-05-11 SE SE06456/66A patent/SE326196B/xx unknown
- 1966-05-11 DK DK241366AA patent/DK123769B/da unknown
- 1966-05-11 NL NL666606441A patent/NL153541B/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI45329B (cs) | 1972-01-31 |
| BR6679335D0 (pt) | 1973-10-23 |
| BE680737A (cs) | 1966-11-09 |
| NL153541B (nl) | 1977-06-15 |
| IL25650A (en) | 1969-11-30 |
| NL6606441A (cs) | 1966-11-14 |
| FR6011M (cs) | 1968-05-06 |
| DE1543653A1 (de) | 1969-09-18 |
| FI45329C (fi) | 1972-05-10 |
| ES326559A1 (es) | 1967-03-01 |
| DK123769B (da) | 1972-07-31 |
| CH498109A (de) | 1970-10-31 |
| DE1543653B2 (de) | 1975-06-05 |
| CH468371A (de) | 1969-02-15 |
| CH513146A (de) | 1971-09-30 |
| SE326196B (cs) | 1970-07-20 |
| NO120270B (cs) | 1970-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1308191A (en) | Thiochroman derivatives and a process for preparing them | |
| NL960021I1 (nl) | Nieuwe trifenylalkaan en alkeenderivaten en de bereiding en toepassing daarvan. | |
| EG18412A (en) | Process for the preparation of substituted indoline derivatives | |
| GB1285016A (en) | 3,4-dihydroisoquinoline derivatives | |
| ES430554A1 (es) | Un procedimiento para la preparacion de 1,3-dimetil-1h-pira-zolo (3,4-b) quinoleinas. | |
| GB1014348A (en) | Antidepressant compositions comprising phenoxyalkylamines | |
| GB1106057A (en) | Novel benzofuran derivatives and the manufacture thereof | |
| ES8502121A1 (es) | Derivados del acido 7 b-((z)-2-(2-aminotiazol-4-il)-2-oximinoacetamido)-3-cefem-4-carboxilico | |
| IL66694A0 (en) | Dibenzazepine derivatives,their preparation and pharmaceutical compositions containing them | |
| ATE23337T1 (de) | Chromanverbindungen. | |
| GB1184762A (en) | Process for the production of Coumarin Derivatives | |
| GB1125112A (en) | New derivatives of diazabicyclo-decane and process for preparing them | |
| PT86282A (en) | Novel anthracyclinederivates a process for preparing and pharmaceutical compounds containing them | |
| KR950702980A (ko) | 정신병 치료제로서의 벤조디옥산메틸아민의 퀴놀린 유도체(Antipsychotic quinoline derivatives of benzodioxanmethylamine) | |
| GB1029915A (en) | Substituted 1,5-diarylpyrroles | |
| AR017488A1 (es) | Compuestos 3-ceto derivados triciclicos de 6-0-metileritromicina, composiciones farmaceuticas, procedimientos de uso para el tratamiento de infecciones yprocedimiento para prepararlos | |
| GB1298524A (en) | Piperazine derivatives and processes for their manufacture | |
| GB1296431A (cs) | ||
| FI844184A0 (fi) | Isokinolinderivat och foerfarande foer framstaellning daerav. | |
| ES294657A1 (es) | Procedimiento para la producciën de nuevos compuestos heterociclicos | |
| US3499010A (en) | Alpha-(phenoxyalkylaminomethyl) 2,3-dihydrobenzofurans | |
| GB1069603A (en) | Improvements in or relating to 9,10-dihydro-anthracene derivatives | |
| GB1055769A (en) | Preparation of 4-amino-5-phenyl-1-pentene compounds | |
| FR2451380A1 (fr) | Nouveaux derives du dithiepinno (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent | |
| GB1106059A (en) | Novel benzofuran derivatives and a process for the manufacture thereof |