GB1101366A - Pharmaceutical compositions and a process for the manufacture thereof - Google Patents
Pharmaceutical compositions and a process for the manufacture thereofInfo
- Publication number
- GB1101366A GB1101366A GB37310/66A GB3731066A GB1101366A GB 1101366 A GB1101366 A GB 1101366A GB 37310/66 A GB37310/66 A GB 37310/66A GB 3731066 A GB3731066 A GB 3731066A GB 1101366 A GB1101366 A GB 1101366A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzodiazepin
- exchange resin
- groups
- acidic ion
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 239000003456 ion exchange resin Substances 0.000 abstract 2
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920002307 Dextran Polymers 0.000 abstract 1
- WINXNKPZLFISPD-UHFFFAOYSA-M Saccharin sodium Chemical compound [Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 WINXNKPZLFISPD-UHFFFAOYSA-M 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- KJONHKAYOJNZEC-UHFFFAOYSA-N nitrazepam Chemical compound C12=CC([N+](=O)[O-])=CC=C2NC(=O)CN=C1C1=CC=CC=C1 KJONHKAYOJNZEC-UHFFFAOYSA-N 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 abstract 1
- 239000004299 sodium benzoate Substances 0.000 abstract 1
- 235000010234 sodium benzoate Nutrition 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- -1 sulphoethyl groups Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1177965 | 1965-08-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1101366A true GB1101366A (en) | 1968-01-31 |
Family
ID=4376790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB37310/66A Expired GB1101366A (en) | 1965-08-20 | 1966-08-19 | Pharmaceutical compositions and a process for the manufacture thereof |
Country Status (14)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1175915A1 (en) * | 2000-07-27 | 2002-01-30 | Rohm And Haas Company | A method for preparing resinates |
| EP1175914A3 (en) * | 2000-07-27 | 2002-05-02 | Rohm And Haas Company | A resinate composition |
| EP1293209A1 (en) * | 2001-09-17 | 2003-03-19 | Rohm And Haas Company | Oral pharmaceutical dosage forms with reduced potential for drug abuse |
| EP1467769B1 (en) * | 2002-01-18 | 2008-05-28 | Rohm and Haas Company | Use of a resinate in the preparation of a formulation for smoking cessation |
-
1966
- 1966-06-24 DE DE1617513A patent/DE1617513C3/de not_active Expired
- 1966-07-27 FI FI661994A patent/FI45726C/fi active
- 1966-07-27 NL NL6610569A patent/NL6610569A/xx unknown
- 1966-08-09 JP JP41051951A patent/JPS507079B1/ja active Pending
- 1966-08-10 IL IL26306A patent/IL26306A/xx unknown
- 1966-08-17 BE BE685589D patent/BE685589A/xx not_active IP Right Cessation
- 1966-08-17 FR FR73217A patent/FR6063M/fr not_active Expired
- 1966-08-19 SE SE11240/66A patent/SE351978B/xx unknown
- 1966-08-19 NO NO164367A patent/NO120752B/no unknown
- 1966-08-19 GB GB37310/66A patent/GB1101366A/en not_active Expired
- 1966-08-19 ES ES0330391A patent/ES330391A1/es not_active Expired
- 1966-08-19 DK DK425066AA patent/DK111277B/da unknown
- 1966-08-20 IT IT19168/66A patent/IT1053660B/it active
-
1969
- 1969-12-31 MY MY196959A patent/MY6900059A/xx unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1175915A1 (en) * | 2000-07-27 | 2002-01-30 | Rohm And Haas Company | A method for preparing resinates |
| EP1175914A3 (en) * | 2000-07-27 | 2002-05-02 | Rohm And Haas Company | A resinate composition |
| KR100869486B1 (ko) * | 2000-07-27 | 2008-11-19 | 롬 앤드 하스 캄파니 | 레지네이트 제조방법 |
| EP1293209A1 (en) * | 2001-09-17 | 2003-03-19 | Rohm And Haas Company | Oral pharmaceutical dosage forms with reduced potential for drug abuse |
| EP1467769B1 (en) * | 2002-01-18 | 2008-05-28 | Rohm and Haas Company | Use of a resinate in the preparation of a formulation for smoking cessation |
| CN1615156B (zh) * | 2002-01-18 | 2012-05-30 | 罗门哈斯公司 | 制备树脂酸酯的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS507079B1 (enrdf_load_stackoverflow) | 1975-03-20 |
| NO120752B (enrdf_load_stackoverflow) | 1970-11-30 |
| BE685589A (enrdf_load_stackoverflow) | 1967-02-17 |
| DE1617513B2 (de) | 1973-08-16 |
| FR6063M (enrdf_load_stackoverflow) | 1968-05-27 |
| DE1617513A1 (de) | 1970-12-23 |
| DE1617513C3 (de) | 1974-04-18 |
| FI45726B (enrdf_load_stackoverflow) | 1972-05-31 |
| IT1053660B (it) | 1981-10-10 |
| FI45726C (fi) | 1972-09-11 |
| SE351978B (enrdf_load_stackoverflow) | 1972-12-18 |
| NL6610569A (enrdf_load_stackoverflow) | 1967-02-21 |
| DK111277B (da) | 1968-07-15 |
| MY6900059A (en) | 1969-12-31 |
| IL26306A (en) | 1970-02-19 |
| ES330391A1 (es) | 1967-10-16 |
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