GB1086192A - Phenylcyclopropane derivatives - Google Patents

Phenylcyclopropane derivatives

Info

Publication number
GB1086192A
GB1086192A GB49345/66A GB4934566A GB1086192A GB 1086192 A GB1086192 A GB 1086192A GB 49345/66 A GB49345/66 A GB 49345/66A GB 4934566 A GB4934566 A GB 4934566A GB 1086192 A GB1086192 A GB 1086192A
Authority
GB
United Kingdom
Prior art keywords
cis
cyclopropane
phenyl
carboxylic acid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB49345/66A
Other languages
English (en)
Inventor
Uberto Maria Teotino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitefin Holding SA
Original Assignee
Whitefin Holding SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitefin Holding SA filed Critical Whitefin Holding SA
Publication of GB1086192A publication Critical patent/GB1086192A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB49345/66A 1963-11-05 1963-11-05 Phenylcyclopropane derivatives Expired GB1086192A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43626/63A GB1086191A (en) 1963-11-05 1963-11-05 Phenylcyclopropane derivatives

Publications (1)

Publication Number Publication Date
GB1086192A true GB1086192A (en) 1967-10-04

Family

ID=10429612

Family Applications (2)

Application Number Title Priority Date Filing Date
GB49345/66A Expired GB1086192A (en) 1963-11-05 1963-11-05 Phenylcyclopropane derivatives
GB43626/63A Expired GB1086191A (en) 1963-11-05 1963-11-05 Phenylcyclopropane derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB43626/63A Expired GB1086191A (en) 1963-11-05 1963-11-05 Phenylcyclopropane derivatives

Country Status (15)

Country Link
JP (2) JPS4821102B1 (cg-RX-API-DMAC10.html)
AT (3) AT273066B (cg-RX-API-DMAC10.html)
BE (1) BE655245A (cg-RX-API-DMAC10.html)
BR (1) BR6464004D0 (cg-RX-API-DMAC10.html)
CH (1) CH482648A (cg-RX-API-DMAC10.html)
DE (1) DE1518207B1 (cg-RX-API-DMAC10.html)
DK (1) DK127726B (cg-RX-API-DMAC10.html)
ES (1) ES305661A1 (cg-RX-API-DMAC10.html)
FI (1) FI43069B (cg-RX-API-DMAC10.html)
FR (4) FR4554M (cg-RX-API-DMAC10.html)
GB (2) GB1086192A (cg-RX-API-DMAC10.html)
IL (1) IL22302A (cg-RX-API-DMAC10.html)
LU (1) LU47291A1 (cg-RX-API-DMAC10.html)
NL (3) NL6412766A (cg-RX-API-DMAC10.html)
SE (1) SE317669B (cg-RX-API-DMAC10.html)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015604A1 (en) * 1979-03-05 1980-09-17 Shell Internationale Researchmaatschappij B.V. Compounds and compositions for use in inhibition of lipogenesis in mammals
US7622589B2 (en) 2005-03-17 2009-11-24 Pfizer Inc. Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists
US8063215B2 (en) 2007-08-22 2011-11-22 Astrazeneca Ab Cyclopropyl amide derivatives
US8993577B2 (en) 2009-02-20 2015-03-31 Astrazeneca Ab Cyclopropyl amide derivatives
US9012452B2 (en) 2010-02-18 2015-04-21 Astrazeneca Ab Processes for making cyclopropyl amide derivatives and intermediates associated therewith

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4103030A (en) * 1974-12-11 1978-07-25 Sumitomo Chemical Company, Limited Novel cyclopropylmethylamine derivatives
EP0188887B1 (en) * 1985-01-17 1991-05-02 Imperial Chemical Industries Plc Tertiary amine compounds
GB2170197B (en) * 1985-01-17 1988-08-24 Ici Plc Tertiary amine compounds
GB8617377D0 (en) * 1986-07-16 1986-08-20 Ici Plc Tertiary amine compounds
WO1992001447A1 (en) * 1990-07-18 1992-02-06 Sandoz Ltd. 2-cyclopropylacetic acid derivatives
US20090203750A1 (en) * 2005-08-24 2009-08-13 Alan Kozikowski 5-HT2C Receptor Agonists as Anorectic Agents
US9108948B2 (en) 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
CA2655604C (en) 2006-06-23 2016-08-09 Abbott Laboratories Cyclopropyl amine derivatives
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
US8853390B2 (en) 2010-09-16 2014-10-07 Abbvie Inc. Processes for preparing 1,2-substituted cyclopropyl derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050559A (en) * 1962-08-21 Substituted phenylcyclopropylamjnes
US3081336A (en) * 1963-03-12 Carbamates
US2997422A (en) * 1959-01-09 1961-08-22 Smith Kline French Lab Monoamine oxidase inhibition
US3106578A (en) * 1960-09-16 1963-10-08 Smith Kline French Lab Nu-phenethyl-2-phenylcyclopropylamine derivatives
US3079403A (en) * 1960-09-19 1963-02-26 Smith Kline French Lab Process for preparing amines

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015604A1 (en) * 1979-03-05 1980-09-17 Shell Internationale Researchmaatschappij B.V. Compounds and compositions for use in inhibition of lipogenesis in mammals
US7622589B2 (en) 2005-03-17 2009-11-24 Pfizer Inc. Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists
US7915448B2 (en) * 2005-03-17 2011-03-29 Pfizer Inc. Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists
US8063215B2 (en) 2007-08-22 2011-11-22 Astrazeneca Ab Cyclopropyl amide derivatives
US9029381B2 (en) 2007-08-22 2015-05-12 Astrazeneca Ab Cyclopropyl amide derivatives
US8993577B2 (en) 2009-02-20 2015-03-31 Astrazeneca Ab Cyclopropyl amide derivatives
US9012452B2 (en) 2010-02-18 2015-04-21 Astrazeneca Ab Processes for making cyclopropyl amide derivatives and intermediates associated therewith

Also Published As

Publication number Publication date
BR6464004D0 (pt) 1973-08-09
AT269832B (de) 1969-04-10
SE317669B (cg-RX-API-DMAC10.html) 1969-11-24
DE1518207B1 (de) 1971-07-01
JPS507598B1 (cg-RX-API-DMAC10.html) 1975-03-27
FI43069B (cg-RX-API-DMAC10.html) 1970-10-01
FR4554M (cg-RX-API-DMAC10.html) 1966-11-02
NL6901128A (cg-RX-API-DMAC10.html) 1969-04-25
ES305661A1 (es) 1965-05-01
CH482648A (de) 1969-12-15
GB1086191A (en) 1967-10-04
LU47291A1 (cg-RX-API-DMAC10.html) 1965-11-05
FR4282M (cg-RX-API-DMAC10.html) 1966-07-11
NL6412766A (cg-RX-API-DMAC10.html) 1965-05-06
AT266812B (de) 1968-12-10
DK127726B (da) 1973-12-24
BE655245A (cg-RX-API-DMAC10.html) 1965-05-04
AT273066B (de) 1969-07-25
FR4555M (cg-RX-API-DMAC10.html) 1966-11-02
JPS4821102B1 (cg-RX-API-DMAC10.html) 1973-06-26
NL128365C (cg-RX-API-DMAC10.html)
IL22302A (en) 1968-10-24
FR4217M (cg-RX-API-DMAC10.html) 1966-06-13

Similar Documents

Publication Publication Date Title
ATE25682T1 (de) Indol-3-carboxamid-derivate.
GB1086191A (en) Phenylcyclopropane derivatives
GB1167563A (en) Novel 3-(2-Substituted Ethyl) Indoles and Processes for Their Manufacture
ATE59632T1 (de) Dihydrodibenzocycloheptylidenethylamin-derivate
TW249804B (cg-RX-API-DMAC10.html)
ES8401067A1 (es) Procedimiento analogo para preparar un derivado de tropil benzoato.
GB1154744A (en) Disubstituted Aminoethanols
GB1062714A (en) -ß-(4'-acyloxy-4'-piperidyl)-ketones
GB1169945A (en) Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives
GB1096006A (en) Substituted biurets
ES475533A1 (es) Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida
GB1141936A (en) Improvements in or relating to benzimidazole derivatives
GB1232836A (cg-RX-API-DMAC10.html)
GB1085672A (en) Substituted phthalazines
ES345835A1 (es) Procedimiento para la preparacion de nuevas fenilacetami- das.
GB1033920A (en) Novel derivatives of triphenylethanols
GB1112334A (en) Improvements in or relating to isoquinolo[2,1-d]benzo[1,4]diazepine derivatives
HUT34951A (en) Process for the production of new carbamates of antilipaemic effect,as well as therapeutic preparations containing them
GB1023718A (en) Substituted phenyl cycloalkyl alkylamines
IE39679L (en) Methods and compositions for killing parasites of warm¹blooded animals
GB1513280A (en) Therapeutic pyrazole derivatives
GB1042299A (en) Quinazoline derivatives
ES8505653A1 (es) Procedimiento para preparar un n-alquil-(3 o 4)piperidinil benzoato
GB1046001A (en) Propanolamine derivatives
GB1203430A (en) Heterocyclic spiro compounds