GB1078049A - Pederin and pseudopederin derivatives - Google Patents
Pederin and pseudopederin derivativesInfo
- Publication number
- GB1078049A GB1078049A GB25059/66A GB2505966A GB1078049A GB 1078049 A GB1078049 A GB 1078049A GB 25059/66 A GB25059/66 A GB 25059/66A GB 2505966 A GB2505966 A GB 2505966A GB 1078049 A GB1078049 A GB 1078049A
- Authority
- GB
- United Kingdom
- Prior art keywords
- catalyst
- pseudopederin
- pederin
- dihydropseudopederin
- dihydropederin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NNNVJFAPLNIYPF-FQZCGRDXSA-N (2s)-n-[(s)-[(2s,4r,6r)-6-[(2s)-2,3-dimethoxypropyl]-4-hydroxy-5,5-dimethyloxan-2-yl]-methoxymethyl]-2-hydroxy-2-[(2r,5r,6r)-2-hydroxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamide Chemical class C1[C@@H](O)C(C)(C)[C@@H](C[C@@H](COC)OC)O[C@@H]1[C@H](OC)NC(=O)[C@@H](O)[C@]1(O)O[C@H](C)[C@H](C)C(=C)C1 NNNVJFAPLNIYPF-FQZCGRDXSA-N 0.000 title abstract 3
- MHRARRIFWSILEQ-UHFFFAOYSA-N Pederin Natural products COCC(CC1OC2C(NC(=O)C(O)C3(CC(=O)C(C)C(C)O3)OC)OCOC2C(OC)C1(C)C)OC MHRARRIFWSILEQ-UHFFFAOYSA-N 0.000 title abstract 3
- ZNEZZONMADKYTB-VRCUBXEUSA-N pederin Chemical compound C1[C@@H](O)C(C)(C)[C@@H](C[C@@H](COC)OC)O[C@@H]1[C@H](OC)NC(=O)[C@@H](O)[C@]1(OC)O[C@H](C)[C@H](C)C(=C)C1 ZNEZZONMADKYTB-VRCUBXEUSA-N 0.000 title abstract 3
- 238000005984 hydrogenation reaction Methods 0.000 abstract 4
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 4
- 239000003054 catalyst Substances 0.000 abstract 3
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical class C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 2
- RHUVSEWLTVNPLK-UHFFFAOYSA-N Pseudopederin Natural products COCC(CC1OC(C(NC(=O)C(O)C2(O)CC(=C)C(C)C(C)O2)OC)C(O)CC1(C)C)OC RHUVSEWLTVNPLK-UHFFFAOYSA-N 0.000 abstract 2
- YKIOKAURTKXMSB-UHFFFAOYSA-N adams's catalyst Chemical compound O=[Pt]=O YKIOKAURTKXMSB-UHFFFAOYSA-N 0.000 abstract 2
- 230000002927 anti-mitotic effect Effects 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910052697 platinum Inorganic materials 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1118265 | 1965-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1078049A true GB1078049A (en) | 1967-08-02 |
Family
ID=11134797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25059/66A Expired GB1078049A (en) | 1965-06-11 | 1966-06-06 | Pederin and pseudopederin derivatives |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR5560M (enrdf_load_html_response) |
| GB (1) | GB1078049A (enrdf_load_html_response) |
-
1966
- 1966-06-06 GB GB25059/66A patent/GB1078049A/en not_active Expired
- 1966-06-06 FR FR64302A patent/FR5560M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR5560M (enrdf_load_html_response) | 1967-11-20 |
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