GB1076858A - A method for stabilizing vitamin b and its analogue - Google Patents
A method for stabilizing vitamin b and its analogueInfo
- Publication number
- GB1076858A GB1076858A GB4109964A GB4109964A GB1076858A GB 1076858 A GB1076858 A GB 1076858A GB 4109964 A GB4109964 A GB 4109964A GB 4109964 A GB4109964 A GB 4109964A GB 1076858 A GB1076858 A GB 1076858A
- Authority
- GB
- United Kingdom
- Prior art keywords
- iodide
- hydrochloride
- sodium
- thiamine
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Aqueous solutions of Vitamin B12 compounds, especially solutions also containing Vitamin B1 compounds, are stabilized by adding hexamine or sodium, potassium, calcium, magnesium, ammonium or triethanolamine iodide. Up to 2% by weight of the solution, e.g. 0.2 to 1%, of the stabilizer may be used. In examples, solutions containing cyanocobalamine, hydroxocobalamine, thiamine hydrochloride, thiamine tetrahydrofurfuryl disulphide hydrochloride and thiamine propyl disulphide hydrochloride, are stabilized with sodium iodide, potassium iodide, ammonium iodide and hexamine.ALSO:Aqueous solutions containing vitamin B12 compounds and vitamin B1 compounds, are stabilized by adding hexamine or sodium, potassium, calcium, magnesium, ammonium or triethanolamine iodide. Up to 2% by weight of the solution, e.g. 0.2 to 1%, of the stabilizer may be used. In Examples sodium iodide, potassium iodide, ammonium iodide and hexamine are added to solutions containing cyanocobalamine, hydroxocobalamine, thiamine hydrochloride, thiamine tetrahydrofurfuryl disulphide hydrochloride, thiamine propyl disulphide hydrochloride, nicotinic acid amide, benzyl alcohol, sodium acetate, acetic acid, pyridoxine, sorbitol, sodium sacchorate, calcium pantothenate and glycerol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5521763 | 1963-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1076858A true GB1076858A (en) | 1967-07-26 |
Family
ID=12992436
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB109864A Expired GB1080626A (en) | 1963-10-14 | 1964-10-08 | A process for stabilizing a vitamin b analogue |
| GB4109964A Expired GB1076858A (en) | 1963-10-14 | 1964-10-08 | A method for stabilizing vitamin b and its analogue |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB109864A Expired GB1080626A (en) | 1963-10-14 | 1964-10-08 | A process for stabilizing a vitamin b analogue |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE1249453B (en) |
| GB (2) | GB1080626A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT376879B (en) * | 1982-10-27 | 1985-01-10 | Gerot Pharmazeutika | METHOD FOR PRODUCING AN INJECTION SOLUTION |
| US4740373A (en) * | 1986-05-27 | 1988-04-26 | Usv Pharmaceutical Corporation | Stabilization of multivitamin/trace elements formulations |
| US4804535A (en) * | 1986-05-27 | 1989-02-14 | Rorer Pharmaceutical Corporation | Stabilization of multivitamin/trace elements formulations |
-
0
- DE DENDAT1249453D patent/DE1249453B/de active Pending
-
1964
- 1964-10-08 GB GB109864A patent/GB1080626A/en not_active Expired
- 1964-10-08 GB GB4109964A patent/GB1076858A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1080626A (en) | 1967-08-23 |
| DE1249453B (en) |
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