GB1068678A - New tricyclic hydroxylamines,their production and use - Google Patents
New tricyclic hydroxylamines,their production and useInfo
- Publication number
- GB1068678A GB1068678A GB18882/65A GB1888265A GB1068678A GB 1068678 A GB1068678 A GB 1068678A GB 18882/65 A GB18882/65 A GB 18882/65A GB 1888265 A GB1888265 A GB 1888265A GB 1068678 A GB1068678 A GB 1068678A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- formula
- carbon atoms
- acid addition
- addition salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002443 hydroxylamines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- -1 alkyl radical Chemical class 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- MKJIEFSOBYUXJB-HOCLYGCPSA-N (3S,11bS)-9,10-dimethoxy-3-isobutyl-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one Chemical compound C1CN2C[C@H](CC(C)C)C(=O)C[C@H]2C2=C1C=C(OC)C(OC)=C2 MKJIEFSOBYUXJB-HOCLYGCPSA-N 0.000 abstract 1
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical compound C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 abstract 1
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 abstract 1
- 229960003147 reserpine Drugs 0.000 abstract 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 229960005333 tetrabenazine Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/94—Oxygen atom, e.g. piperidine N-oxide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Adhesive Tapes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH596364A CH439322A (de) | 1964-05-06 | 1964-05-06 | Verfahren zur Herstellung von neuen tricyclischen Hydroxylaminen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1068678A true GB1068678A (en) | 1967-05-10 |
Family
ID=4302192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18882/65A Expired GB1068678A (en) | 1964-05-06 | 1965-05-05 | New tricyclic hydroxylamines,their production and use |
| GB17205/66A Expired GB1068679A (en) | 1964-05-06 | 1965-05-05 | New tricyclic hydroxylamines,their production and use |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17205/66A Expired GB1068679A (en) | 1964-05-06 | 1965-05-05 | New tricyclic hydroxylamines,their production and use |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3358026A (cg-RX-API-DMAC7.html) |
| AT (1) | AT258266B (cg-RX-API-DMAC7.html) |
| BE (1) | BE663516A (cg-RX-API-DMAC7.html) |
| BR (1) | BR6569425D0 (cg-RX-API-DMAC7.html) |
| ES (1) | ES312596A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI42323B (cg-RX-API-DMAC7.html) |
| FR (1) | FR4649M (cg-RX-API-DMAC7.html) |
| GB (2) | GB1068678A (cg-RX-API-DMAC7.html) |
| IL (1) | IL23486A (cg-RX-API-DMAC7.html) |
| NL (2) | NL6505680A (cg-RX-API-DMAC7.html) |
| NO (1) | NO118488B (cg-RX-API-DMAC7.html) |
| SE (1) | SE320965B (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB999879A (en) * | 1960-11-09 | 1965-07-28 | Sandoz Ag | Improvements in or relating to dibenzocycloheptane derivatives |
| DE3623940A1 (de) * | 1986-07-16 | 1988-01-21 | Bayer Ag | Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3072530A (en) * | 1958-09-12 | 1963-01-08 | Sandoz Ag | Therapeutic indoles for psychic stimulation and relief of mental depression |
| US3051625A (en) * | 1959-07-01 | 1962-08-28 | Pfizer & Co C | Dithiocarbamate tumor-inhibitory process |
| US3190893A (en) * | 1961-02-17 | 1965-06-22 | Kefalas As | Method of producing 9, 10-dihydroanthracenes |
| US3098010A (en) * | 1961-10-05 | 1963-07-16 | Abbott Lab | Process for increasing the effects of monoamine oxidase inhibitors by means of catechol-omicron-methyl transferase |
| US3196150A (en) * | 1963-01-15 | 1965-07-20 | Pfizer & Co C | 2 chloro-9-[13-(4 carbamoyl-1-piperazinyl) propylidene]thioxanthene derivatives |
| US3224943A (en) * | 1964-03-06 | 1965-12-21 | Hercules Powder Co Ltd | Process for retarding the growth of tumors |
-
0
- NL NL130101D patent/NL130101C/xx active
-
1965
- 1965-05-03 US US452872A patent/US3358026A/en not_active Expired - Lifetime
- 1965-05-03 FI FI1077/65A patent/FI42323B/fi active
- 1965-05-04 NL NL6505680A patent/NL6505680A/xx unknown
- 1965-05-05 ES ES0312596A patent/ES312596A1/es not_active Expired
- 1965-05-05 SE SE5900/65A patent/SE320965B/xx unknown
- 1965-05-05 GB GB18882/65A patent/GB1068678A/en not_active Expired
- 1965-05-05 NO NO157961A patent/NO118488B/no unknown
- 1965-05-05 IL IL23486A patent/IL23486A/xx unknown
- 1965-05-05 BR BR169425/65A patent/BR6569425D0/pt unknown
- 1965-05-05 GB GB17205/66A patent/GB1068679A/en not_active Expired
- 1965-05-05 AT AT411265A patent/AT258266B/de active
- 1965-05-06 BE BE663516D patent/BE663516A/xx unknown
- 1965-08-04 FR FR27175A patent/FR4649M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL23486A (en) | 1968-09-26 |
| ES312596A1 (es) | 1966-03-01 |
| SE320965B (cg-RX-API-DMAC7.html) | 1970-02-23 |
| NL130101C (cg-RX-API-DMAC7.html) | |
| NO118488B (cg-RX-API-DMAC7.html) | 1970-01-05 |
| FR4649M (cg-RX-API-DMAC7.html) | 1966-12-05 |
| AT258266B (de) | 1967-11-10 |
| GB1068679A (en) | 1967-05-10 |
| BR6569425D0 (pt) | 1973-08-02 |
| BE663516A (cg-RX-API-DMAC7.html) | 1965-11-08 |
| US3358026A (en) | 1967-12-12 |
| NL6505680A (cg-RX-API-DMAC7.html) | 1965-11-08 |
| FI42323B (cg-RX-API-DMAC7.html) | 1970-03-31 |
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