GB1067203A - Improvements in or relating to the production of isoxazole compounds and the products thereof - Google Patents

Improvements in or relating to the production of isoxazole compounds and the products thereof

Info

Publication number
GB1067203A
GB1067203A GB1313865A GB1313865A GB1067203A GB 1067203 A GB1067203 A GB 1067203A GB 1313865 A GB1313865 A GB 1313865A GB 1313865 A GB1313865 A GB 1313865A GB 1067203 A GB1067203 A GB 1067203A
Authority
GB
United Kingdom
Prior art keywords
relating
products
production
isoxazole compounds
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1313865A
Inventor
Hideo Kano
Ikuo Adachi
Ryonosuke Kido
Katsumi Hirose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to GB1313865A priority Critical patent/GB1067203A/en
Publication of GB1067203A publication Critical patent/GB1067203A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

The invention comprises isoxazole compounds of the Formula I <FORM:1067203/C2/1> wherein each of R1 and R11 is a hydrogen atom or an aliphatic hydrocarbon residue or wherein R1 and R11 together with the nitrogen atom represent a heterocyclic group and A is an alkylene group of 1 to 5 carbon atoms, and its hydrochloride. They may be prepared by reacting a 3-p-chlorophenyl-5-(-A-Cl)-isoxazole with the corresponding amine R1R11NH. Pharmaceutical compositions comprising an oxazole of Formula I, or its hydrochloride, together with an inert diluent or carrier may be employed as antipyretics, analgesics, antitussives and/or anti-inflammatory agents.
GB1313865A 1964-02-26 1964-02-26 Improvements in or relating to the production of isoxazole compounds and the products thereof Expired GB1067203A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1313865A GB1067203A (en) 1964-02-26 1964-02-26 Improvements in or relating to the production of isoxazole compounds and the products thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1313865A GB1067203A (en) 1964-02-26 1964-02-26 Improvements in or relating to the production of isoxazole compounds and the products thereof

Publications (1)

Publication Number Publication Date
GB1067203A true GB1067203A (en) 1967-05-03

Family

ID=10017540

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1313865A Expired GB1067203A (en) 1964-02-26 1964-02-26 Improvements in or relating to the production of isoxazole compounds and the products thereof

Country Status (1)

Country Link
GB (1) GB1067203A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0189771A2 (en) * 1985-01-22 1986-08-06 Hoechst-Roussel Pharmaceuticals Incorporated (Isoxazol-3-yl)arylmethanones, a process for their preparation and their use as medicaments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0189771A2 (en) * 1985-01-22 1986-08-06 Hoechst-Roussel Pharmaceuticals Incorporated (Isoxazol-3-yl)arylmethanones, a process for their preparation and their use as medicaments
EP0189771A3 (en) * 1985-01-22 1986-10-08 Hoechst-Roussel Pharmaceuticals Incorporated (isoxazol-3-yl)arylmethanones, a process for their preparation and their use as medicaments

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