GB1061571A - N,n'-disubstituted piperazines and process for their manufacture - Google Patents

N,n'-disubstituted piperazines and process for their manufacture

Info

Publication number
GB1061571A
GB1061571A GB170264A GB170264A GB1061571A GB 1061571 A GB1061571 A GB 1061571A GB 170264 A GB170264 A GB 170264A GB 170264 A GB170264 A GB 170264A GB 1061571 A GB1061571 A GB 1061571A
Authority
GB
United Kingdom
Prior art keywords
acid addition
phenyl
addition salt
converting
free base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB170264A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB1061571A publication Critical patent/GB1061571A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB170264A 1963-01-14 1964-01-14 N,n'-disubstituted piperazines and process for their manufacture Expired GB1061571A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US25104763A 1963-01-14 1963-01-14
US25778463A 1963-02-11 1963-02-11
US25778363A 1963-02-11 1963-02-11
US27189063A 1963-04-10 1963-04-10
US32133463A 1963-11-04 1963-11-04
US32134263A 1963-11-04 1963-11-04

Publications (1)

Publication Number Publication Date
GB1061571A true GB1061571A (en) 1967-03-15

Family

ID=27559375

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1053301D Active GB1053301A (US07321065-20080122-C00020.png) 1963-01-14
GB170264A Expired GB1061571A (en) 1963-01-14 1964-01-14 N,n'-disubstituted piperazines and process for their manufacture

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1053301D Active GB1053301A (US07321065-20080122-C00020.png) 1963-01-14

Country Status (5)

Country Link
BE (3) BE642429A (US07321065-20080122-C00020.png)
CH (5) CH449636A (US07321065-20080122-C00020.png)
DE (1) DE1232587B (US07321065-20080122-C00020.png)
FR (1) FR3734M (US07321065-20080122-C00020.png)
GB (2) GB1061571A (US07321065-20080122-C00020.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034284A2 (en) * 1980-02-18 1981-08-26 Tanabe Seiyaku Co., Ltd. Piperazine derivative, processes for preparing the same and therapeutic compositions containing it
US7485651B2 (en) 1998-03-31 2009-02-03 Acadia Pharmaceuticals, Inc. Compounds with activity on muscarinic receptors

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5513209A (en) * 1978-07-11 1980-01-30 Synthelabo Antidepressive made of piperazine derivative
FR2568878B1 (fr) * 1984-08-07 1986-11-21 Cortial Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique
DE3715763A1 (de) * 1987-05-12 1988-11-24 Hoechst Ag Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel
CA2326804C (en) * 1998-03-31 2006-05-02 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034284A2 (en) * 1980-02-18 1981-08-26 Tanabe Seiyaku Co., Ltd. Piperazine derivative, processes for preparing the same and therapeutic compositions containing it
EP0034284A3 (en) * 1980-02-18 1981-12-09 Tanabe Seiyaku Co., Ltd. Piperazine derivative and processes for preparing the same
US7485651B2 (en) 1998-03-31 2009-02-03 Acadia Pharmaceuticals, Inc. Compounds with activity on muscarinic receptors

Also Published As

Publication number Publication date
BE642427A (US07321065-20080122-C00020.png) 1964-07-13
BE642429A (US07321065-20080122-C00020.png) 1964-07-13
CH449633A (de) 1968-01-15
BE642428A (US07321065-20080122-C00020.png) 1964-07-13
CH449030A (de) 1967-12-31
CH449635A (de) 1968-01-15
FR3734M (fr) 1965-12-06
CH449634A (de) 1968-01-15
CH449636A (de) 1968-01-15
DE1232587B (de) 1967-01-19
GB1053301A (US07321065-20080122-C00020.png)

Similar Documents

Publication Publication Date Title
GB1047935A (en) Substituted piperazines and preparation thereof
ES337526A1 (es) Un procedimiento para la manufactura de nuevas piperazinas.
ES476786A1 (es) Procedimiento para preparar nuevos derivados de tetrahidro- piridinilindol.
ES425626A1 (es) Un procedimiento para preparar compuestos de acil-xilidida.
GB1120463A (en) Derivatives of 1,3-diazafluoranthene-1-oxide
ES382014A1 (es) Procedimiento para la preparacion de 1-fenoxi-2-hidroxi - - 3 - cicloalcohilaminopropanos racemicos u opticamente ac- tivados y sus sales por adicion de acido.
GB1061571A (en) N,n'-disubstituted piperazines and process for their manufacture
GB1173227A (en) Amino-Isoquinolines
GB1104145A (en) Pyrazolo-pyridine derivatives
GB1061306A (en) 4-substituted-2-benzhydryl-2-butanol derivatives
GB1033920A (en) Novel derivatives of triphenylethanols
GB1125112A (en) New derivatives of diazabicyclo-decane and process for preparing them
GB933504A (en) New piperidine derivatives and methods for preparing the same
GB1023718A (en) Substituted phenyl cycloalkyl alkylamines
ES350955A1 (es) Un procedimiento para preparar derivados de acido barbitu- rico.
GB1090283A (en) (2-aminoethyl)-hydroquinones
GB1142508A (en) Pyrrole derivatives
GB1377610A (en) 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof
GB1181295A (en) Improvements in or relating to Naphthalene Derivatives and the Manufacture Thereof
GB883220A (en) Improvements in or relating to morpholine derivatives
GB1113802A (en) Improvements in or relating to substituted quinolines and the manufacture thereof
GB1060069A (en) Improvements in or relating to phenylethanolamines
ES336945A1 (es) Un metodo de preparar 5-bencil-pirimidinas.
GB1031743A (en) Improvements in or relating to dibenzthiepin derivatives
ES428535A1 (es) Un procedimiento para la preparacion de cicloserina n-sus- tituida.