GB1053143A - - Google Patents

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Publication number
GB1053143A
GB1053143A GB1053143DA GB1053143A GB 1053143 A GB1053143 A GB 1053143A GB 1053143D A GB1053143D A GB 1053143DA GB 1053143 A GB1053143 A GB 1053143A
Authority
GB
United Kingdom
Prior art keywords
amylopectin
sulphated
salts
sulphur trioxide
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of GB1053143A publication Critical patent/GB1053143A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B35/00Preparation of derivatives of amylopectin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B35/00Preparation of derivatives of amylopectin
    • C08B35/02Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Detergent Compositions (AREA)

Abstract

1,053,143. Sulphated amylopectin. G. D. SEARLE & CO. March 17, 1964 [March 29, 1963], No. 11272/64. Heading C3U. The invention comprises water-soluble sulphated amylopectin, and water-soluble salts thereof, of molecular weight 1-30 x 10<SP>7</SP> and containing 1 to 1À8 sulphate groups per glucose unit, the sulphated amylopectin being derived from potato starch amylopectin, of molecular weight greater than 1 x 10<SP>7</SP> which has suffered minimum degradation, by sulphation under conditions causing minimal degradation. Specified salts are non-toxic salts formed with metallic cations, e.g. sodium, ammonium ions and organic bases, e.g. trimethylamine and triethylamine. Sulphation of the amylopectin may be effected by treatment with, e.g., chlorosulphonic acid, alkali metal chlorosulphonates, sulphamic acid, sulphuryl chloride, gaseous sulphur trioxide, a mixture of sodium nitrite and sodium bisulphite, and organic complexes of sulphur trioxide, e.g. sulphur trioxide, complexes of trimethylamine, triethylamine, pyridine, dimethylaniline, dioxane and bis-(2-ohloroethyl) ether. The sulphated amylopectin and salts thereof may be isolated and purified by processes of centrifugation, lyophilization, dialysis, alcohol precipitation and precipitation with quaternary ammonium salts.
GB1053143D 1963-03-29 Expired GB1053143A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26916263A 1963-03-29 1963-03-29

Publications (1)

Publication Number Publication Date
GB1053143A true GB1053143A (en) 1900-01-01

Family

ID=23026061

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1053143D Expired GB1053143A (en) 1963-03-29

Country Status (9)

Country Link
AT (1) AT269900B (en)
BE (1) BE645762A (en)
BR (1) BR6457878D0 (en)
CH (1) CH465574A (en)
DE (1) DE1468964C3 (en)
DK (1) DK130794B (en)
FR (2) FR1595503A (en)
GB (1) GB1053143A (en)
SE (1) SE336671B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012579A1 (en) * 1989-04-20 1990-11-01 Louis George Lange, Iii The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5521303A (en) * 1994-10-13 1996-05-28 Cv Therapeutics, Inc. Method of manufacturing non-absorbable synthetic sulfated polysaccharides
US6632801B1 (en) 1994-10-13 2003-10-14 Cv Therapeutics, Inc. Method and composition for inhibiting human cholesterol esterase
US7071174B1 (en) 1994-10-13 2006-07-04 Cv Therapeutics, Inc. Method and composition for inhibiting cholesterol esterase

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012579A1 (en) * 1989-04-20 1990-11-01 Louis George Lange, Iii The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
AU633569B2 (en) * 1989-04-20 1993-02-04 Louis George Lange Iii The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5521303A (en) * 1994-10-13 1996-05-28 Cv Therapeutics, Inc. Method of manufacturing non-absorbable synthetic sulfated polysaccharides
US6632801B1 (en) 1994-10-13 2003-10-14 Cv Therapeutics, Inc. Method and composition for inhibiting human cholesterol esterase
US7071174B1 (en) 1994-10-13 2006-07-04 Cv Therapeutics, Inc. Method and composition for inhibiting cholesterol esterase

Also Published As

Publication number Publication date
CH465574A (en) 1968-11-30
SE336671B (en) 1971-07-12
BE645762A (en) 1964-09-28
BR6457878D0 (en) 1973-08-07
DE1468964A1 (en) 1969-02-20
DE1468964B2 (en) 1973-05-24
DE1468964C3 (en) 1973-12-20
DK130794C (en) 1975-09-15
DK130794B (en) 1975-04-14
FR3628M (en) 1965-10-18
AT269900B (en) 1969-04-10
FR1595503A (en) 1970-06-15

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