GB1053143A - - Google Patents
Info
- Publication number
- GB1053143A GB1053143A GB1053143DA GB1053143A GB 1053143 A GB1053143 A GB 1053143A GB 1053143D A GB1053143D A GB 1053143DA GB 1053143 A GB1053143 A GB 1053143A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amylopectin
- sulphated
- salts
- sulphur trioxide
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B35/00—Preparation of derivatives of amylopectin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B35/00—Preparation of derivatives of amylopectin
- C08B35/02—Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Detergent Compositions (AREA)
Abstract
1,053,143. Sulphated amylopectin. G. D. SEARLE & CO. March 17, 1964 [March 29, 1963], No. 11272/64. Heading C3U. The invention comprises water-soluble sulphated amylopectin, and water-soluble salts thereof, of molecular weight 1-30 x 10<SP>7</SP> and containing 1 to 1À8 sulphate groups per glucose unit, the sulphated amylopectin being derived from potato starch amylopectin, of molecular weight greater than 1 x 10<SP>7</SP> which has suffered minimum degradation, by sulphation under conditions causing minimal degradation. Specified salts are non-toxic salts formed with metallic cations, e.g. sodium, ammonium ions and organic bases, e.g. trimethylamine and triethylamine. Sulphation of the amylopectin may be effected by treatment with, e.g., chlorosulphonic acid, alkali metal chlorosulphonates, sulphamic acid, sulphuryl chloride, gaseous sulphur trioxide, a mixture of sodium nitrite and sodium bisulphite, and organic complexes of sulphur trioxide, e.g. sulphur trioxide, complexes of trimethylamine, triethylamine, pyridine, dimethylaniline, dioxane and bis-(2-ohloroethyl) ether. The sulphated amylopectin and salts thereof may be isolated and purified by processes of centrifugation, lyophilization, dialysis, alcohol precipitation and precipitation with quaternary ammonium salts.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26916263A | 1963-03-29 | 1963-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1053143A true GB1053143A (en) | 1900-01-01 |
Family
ID=23026061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1053143D Expired GB1053143A (en) | 1963-03-29 |
Country Status (9)
Country | Link |
---|---|
AT (1) | AT269900B (en) |
BE (1) | BE645762A (en) |
BR (1) | BR6457878D0 (en) |
CH (1) | CH465574A (en) |
DE (1) | DE1468964C3 (en) |
DK (1) | DK130794B (en) |
FR (2) | FR1595503A (en) |
GB (1) | GB1053143A (en) |
SE (1) | SE336671B (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990012579A1 (en) * | 1989-04-20 | 1990-11-01 | Louis George Lange, Iii | The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption |
US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
US5521303A (en) * | 1994-10-13 | 1996-05-28 | Cv Therapeutics, Inc. | Method of manufacturing non-absorbable synthetic sulfated polysaccharides |
US6632801B1 (en) | 1994-10-13 | 2003-10-14 | Cv Therapeutics, Inc. | Method and composition for inhibiting human cholesterol esterase |
US7071174B1 (en) | 1994-10-13 | 2006-07-04 | Cv Therapeutics, Inc. | Method and composition for inhibiting cholesterol esterase |
-
0
- GB GB1053143D patent/GB1053143A/en not_active Expired
-
1964
- 1964-03-25 CH CH394064A patent/CH465574A/en unknown
- 1964-03-25 DK DK156364A patent/DK130794B/en unknown
- 1964-03-25 BR BR15787864A patent/BR6457878D0/en unknown
- 1964-03-26 SE SE386464A patent/SE336671B/xx unknown
- 1964-03-26 FR FR1595503D patent/FR1595503A/fr not_active Expired
- 1964-03-26 BE BE645762D patent/BE645762A/xx unknown
- 1964-03-26 AT AT264164A patent/AT269900B/en active
- 1964-03-26 DE DE19641468964 patent/DE1468964C3/en not_active Expired
- 1964-06-25 FR FR979542A patent/FR3628M/en not_active Expired
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990012579A1 (en) * | 1989-04-20 | 1990-11-01 | Louis George Lange, Iii | The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption |
US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
US5063210A (en) * | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
AU633569B2 (en) * | 1989-04-20 | 1993-02-04 | Louis George Lange Iii | The use of non-absorbable synthetic sulfated polysaccharides to decrease cholesterol absorption |
US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
US5521303A (en) * | 1994-10-13 | 1996-05-28 | Cv Therapeutics, Inc. | Method of manufacturing non-absorbable synthetic sulfated polysaccharides |
US6632801B1 (en) | 1994-10-13 | 2003-10-14 | Cv Therapeutics, Inc. | Method and composition for inhibiting human cholesterol esterase |
US7071174B1 (en) | 1994-10-13 | 2006-07-04 | Cv Therapeutics, Inc. | Method and composition for inhibiting cholesterol esterase |
Also Published As
Publication number | Publication date |
---|---|
CH465574A (en) | 1968-11-30 |
SE336671B (en) | 1971-07-12 |
BE645762A (en) | 1964-09-28 |
BR6457878D0 (en) | 1973-08-07 |
DE1468964A1 (en) | 1969-02-20 |
DE1468964B2 (en) | 1973-05-24 |
DE1468964C3 (en) | 1973-12-20 |
DK130794C (en) | 1975-09-15 |
DK130794B (en) | 1975-04-14 |
FR3628M (en) | 1965-10-18 |
AT269900B (en) | 1969-04-10 |
FR1595503A (en) | 1970-06-15 |
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