GB1049026A - Process for the manufacture of 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesterones and new 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesterones - Google Patents
Process for the manufacture of 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesterones and new 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesteronesInfo
- Publication number
- GB1049026A GB1049026A GB2126764A GB2126764A GB1049026A GB 1049026 A GB1049026 A GB 1049026A GB 2126764 A GB2126764 A GB 2126764A GB 2126764 A GB2126764 A GB 2126764A GB 1049026 A GB1049026 A GB 1049026A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxyprogesterones
- methylene
- manufacture
- new
- hydrolysed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises compounds having the formula <FORM:1049026/C2/1> in which R is hydrogen, halogen or alkyl and a process for the manufacture thereof in which the corresponding 17-ester is hydrolysed, preferably with an alkaline hydrolysing agent, and the resulting free 17a -hydroxyl compound is isolated.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DESCH33365A DE1189991B (en) | 1963-05-31 | 1963-05-31 | Process for the preparation of 1,2alpha-methylene-delta-17alpha-hydroxy-progesterones |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1049026A true GB1049026A (en) | 1966-11-23 |
Family
ID=7432762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2126764A Expired GB1049026A (en) | 1963-05-31 | 1964-05-22 | Process for the manufacture of 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesterones and new 1,2ª‡-methylene-í¸-17ª‡-hydroxyprogesterones |
Country Status (4)
Country | Link |
---|---|
CH (1) | CH433285A (en) |
DE (1) | DE1189991B (en) |
GB (1) | GB1049026A (en) |
NL (1) | NL142671B (en) |
-
1963
- 1963-05-31 DE DESCH33365A patent/DE1189991B/en active Pending
-
1964
- 1964-04-28 NL NL6404660A patent/NL142671B/en not_active IP Right Cessation
- 1964-05-22 CH CH668564A patent/CH433285A/en unknown
- 1964-05-22 GB GB2126764A patent/GB1049026A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1189991B (en) | 1965-04-01 |
NL6404660A (en) | 1964-12-01 |
NL142671B (en) | 1974-07-15 |
CH433285A (en) | 1967-04-15 |
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