GB1040177A - New 3:6-dioxo-a-nor-b-homo-steroids and process for their manufacture - Google Patents
New 3:6-dioxo-a-nor-b-homo-steroids and process for their manufactureInfo
- Publication number
- GB1040177A GB1040177A GB11774/63A GB1177463A GB1040177A GB 1040177 A GB1040177 A GB 1040177A GB 11774/63 A GB11774/63 A GB 11774/63A GB 1177463 A GB1177463 A GB 1177463A GB 1040177 A GB1040177 A GB 1040177A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- oxo
- oxido
- homo
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 150000004965 peroxy acids Chemical class 0.000 abstract 2
- XIIAYQZJNBULGD-UHFFFAOYSA-N (5alpha)-cholestane Natural products C1CC2CCCCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 XIIAYQZJNBULGD-UHFFFAOYSA-N 0.000 abstract 1
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- QSHQKIURKJITMZ-OBUPQJQESA-N 5β-cholane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCC)[C@@]2(C)CC1 QSHQKIURKJITMZ-OBUPQJQESA-N 0.000 abstract 1
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 150000001737 cardanolides Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- XIIAYQZJNBULGD-LDHZKLTISA-N cholestane Chemical compound C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 XIIAYQZJNBULGD-LDHZKLTISA-N 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 150000002084 enol ethers Chemical class 0.000 abstract 1
- 150000002085 enols Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 125000000686 lactone group Chemical group 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- INLFWQCRAJUDCR-LYLBMTSKSA-N spirostane Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CCCCC4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@@H](C)CO1 INLFWQCRAJUDCR-LYLBMTSKSA-N 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J69/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one atom and expansion of only one ring by one atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH353362A CH412876A (de) | 1962-03-23 | 1962-03-23 | Verfahren zur Herstellung neuer 3,6-Dioxo-A-nor-B-homo-steroide |
| CH984462 | 1962-08-17 | ||
| CH1442262 | 1962-12-07 | ||
| CH288063 | 1963-03-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1040177A true GB1040177A (en) | 1966-08-24 |
Family
ID=27428524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11774/63A Expired GB1040177A (en) | 1962-03-23 | 1963-03-25 | New 3:6-dioxo-a-nor-b-homo-steroids and process for their manufacture |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3758588A (enrdf_load_stackoverflow) |
| AT (1) | AT257062B (enrdf_load_stackoverflow) |
| BR (1) | BR6347875D0 (enrdf_load_stackoverflow) |
| DK (1) | DK117223B (enrdf_load_stackoverflow) |
| ES (1) | ES286306A1 (enrdf_load_stackoverflow) |
| FR (1) | FR3015M (enrdf_load_stackoverflow) |
| GB (1) | GB1040177A (enrdf_load_stackoverflow) |
| MY (1) | MY7000065A (enrdf_load_stackoverflow) |
| NL (2) | NL122977C (enrdf_load_stackoverflow) |
| SE (1) | SE314062B (enrdf_load_stackoverflow) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3040093A (en) * | 1960-11-07 | 1962-06-19 | Roussel Uclaf | A-nor-b-homo-steroids and process of preparing same |
| FR1369320A (fr) * | 1961-06-16 | 1964-08-14 | Roussel Uclaf | Nouveaux a-nor b-homo stéroïdes et leur obtention |
| US3138635A (en) * | 1961-06-19 | 1964-06-23 | Roussel Uclaf | Novel alpha-nor-beta-homo-steroids |
-
0
- NL NL290562D patent/NL290562A/xx unknown
- NL NL122977D patent/NL122977C/xx active
-
1963
- 1963-03-22 SE SE3166/63A patent/SE314062B/xx unknown
- 1963-03-22 ES ES286306A patent/ES286306A1/es not_active Expired
- 1963-03-22 DK DK132863AA patent/DK117223B/da unknown
- 1963-03-22 BR BR147875/63A patent/BR6347875D0/pt unknown
- 1963-03-25 AT AT235263A patent/AT257062B/de active
- 1963-03-25 GB GB11774/63A patent/GB1040177A/en not_active Expired
- 1963-06-21 FR FR938889A patent/FR3015M/fr not_active Expired
-
1969
- 1969-07-08 US US00840025A patent/US3758588A/en not_active Expired - Lifetime
-
1970
- 1970-12-31 MY MY197065A patent/MY7000065A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES286306A1 (es) | 1963-10-16 |
| FR3015M (fr) | 1964-12-21 |
| DK117223B (da) | 1970-03-31 |
| NL290562A (enrdf_load_stackoverflow) | |
| US3758588A (en) | 1973-09-11 |
| NL122977C (enrdf_load_stackoverflow) | |
| AT257062B (de) | 1967-09-25 |
| MY7000065A (en) | 1970-12-31 |
| SE314062B (enrdf_load_stackoverflow) | 1969-09-01 |
| BR6347875D0 (pt) | 1973-08-14 |
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