GB1039722A - Process for the manufacture of a foot-and-mouth disease vaccine containing a live virus - Google Patents
Process for the manufacture of a foot-and-mouth disease vaccine containing a live virusInfo
- Publication number
- GB1039722A GB1039722A GB20031/63A GB2003163A GB1039722A GB 1039722 A GB1039722 A GB 1039722A GB 20031/63 A GB20031/63 A GB 20031/63A GB 2003163 A GB2003163 A GB 2003163A GB 1039722 A GB1039722 A GB 1039722A
- Authority
- GB
- United Kingdom
- Prior art keywords
- virus
- foot
- mouth disease
- animal
- pathogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
- A61K39/135—Foot- and mouth-disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A foot-and-mouth disease vaccine containing live virus is prepared by subjecting a pathogenic foot-and-mouth disease virus to serial passage at 37 DEG C. through primary cell cultures containing Hank's or Earle's solution, lactalbumin hydrolysate, serum and cells obtained by the trypsinization of an organ of a hoofed animal until the said virus destroys a cell monolayer of one serial passage, and then continuing the serial passage through the same type primary cell cultures at 26 to 30 DEG C., and preferably 28 DEG C., until the virus is so modified that when parenterally injected into a hoofed animal, it is non-pathogenic towards the animal and produces in the animal an immunizing action similar to that of the pathogenic virus. In the example, calves serum and cells obtained from the kidneys of freshly slaughtered calves are used.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB67300A DE1174016B (en) | 1962-05-18 | 1962-05-18 | Process for the production of a live vaccine against foot and mouth disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1039722A true GB1039722A (en) | 1966-08-17 |
Family
ID=6975473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20031/63A Expired GB1039722A (en) | 1962-05-18 | 1963-05-20 | Process for the manufacture of a foot-and-mouth disease vaccine containing a live virus |
Country Status (3)
| Country | Link |
|---|---|
| BR (1) | BR6349184D0 (en) |
| DE (1) | DE1174016B (en) |
| GB (1) | GB1039722A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2088038A1 (en) * | 1970-05-11 | 1972-01-07 | Bellon Labor Sa Roger | |
| CN111184221A (en) * | 2019-10-21 | 2020-05-22 | 青海宏健生物科技集团有限公司 | Yak tendon collagen oral liquid and preparation method thereof |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4287178A (en) * | 1974-03-25 | 1981-09-01 | Pitman-Moore, Inc. | Feline rhinotracheitis vaccine and production and use thereof |
| US4303645A (en) | 1980-04-18 | 1981-12-01 | Cornell Research Foundation, Inc. | Modified living canine parvovirus vaccine |
-
1962
- 1962-05-18 DE DEB67300A patent/DE1174016B/en active Pending
-
1963
- 1963-05-16 BR BR149184/63A patent/BR6349184D0/en unknown
- 1963-05-20 GB GB20031/63A patent/GB1039722A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2088038A1 (en) * | 1970-05-11 | 1972-01-07 | Bellon Labor Sa Roger | |
| CN111184221A (en) * | 2019-10-21 | 2020-05-22 | 青海宏健生物科技集团有限公司 | Yak tendon collagen oral liquid and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1174016B (en) | 1964-07-16 |
| BR6349184D0 (en) | 1973-08-02 |
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