GB1038505A - Antileprosy ointment - Google Patents

Antileprosy ointment

Info

Publication number
GB1038505A
GB1038505A GB2216663A GB2216663A GB1038505A GB 1038505 A GB1038505 A GB 1038505A GB 2216663 A GB2216663 A GB 2216663A GB 2216663 A GB2216663 A GB 2216663A GB 1038505 A GB1038505 A GB 1038505A
Authority
GB
United Kingdom
Prior art keywords
ointment
antileprosy
hydrazinoquinoxaline
mercapto
dimercaptoquinoxaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2216663A
Inventor
Tadashi Hirako
Sadae Tsutsumi
Kazuo Asano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to GB2216663A priority Critical patent/GB1038505A/en
Publication of GB1038505A publication Critical patent/GB1038505A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

2 - Mercapto - 3 - hydrazinoquinoxaline is prepared by reacting 2,3-dimercaptoquinoxaline with hydrazine hydrate. Water-soluble salts may be formed by treating the product with mineral acids.ALSO:An antileprosy ointment comprises 0.5 to 5% by weight of 2-mercapto-3-hydrazinoquinoxaline in an ointment base chosen from fats, fatty oils, lanolin, petroleum jelly, glycerine, wax, higher fatty alcohols, polyalkylene glycols or a mixture of two or more thereof.
GB2216663A 1963-06-04 1963-06-04 Antileprosy ointment Expired GB1038505A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2216663A GB1038505A (en) 1963-06-04 1963-06-04 Antileprosy ointment

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2216663A GB1038505A (en) 1963-06-04 1963-06-04 Antileprosy ointment

Publications (1)

Publication Number Publication Date
GB1038505A true GB1038505A (en) 1966-08-10

Family

ID=10175024

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2216663A Expired GB1038505A (en) 1963-06-04 1963-06-04 Antileprosy ointment

Country Status (1)

Country Link
GB (1) GB1038505A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010426A1 (en) * 1978-10-20 1980-04-30 Eli Lilly And Company Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof
EP2536431A2 (en) * 2010-02-19 2012-12-26 The Regents of The University of Michigan Compositions and methods for inhibiting mmset

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010426A1 (en) * 1978-10-20 1980-04-30 Eli Lilly And Company Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof
EP2536431A2 (en) * 2010-02-19 2012-12-26 The Regents of The University of Michigan Compositions and methods for inhibiting mmset
EP2536431A4 (en) * 2010-02-19 2014-01-08 Univ Michigan Compositions and methods for inhibiting mmset
US8697407B2 (en) 2010-02-19 2014-04-15 The Regents Of The University Of Michigan Compositions and methods for inhibiting MMSET

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