GB1036125A - Process for the purification of cephalosporin c - Google Patents
Process for the purification of cephalosporin cInfo
- Publication number
- GB1036125A GB1036125A GB5670/62A GB567062A GB1036125A GB 1036125 A GB1036125 A GB 1036125A GB 5670/62 A GB5670/62 A GB 5670/62A GB 567062 A GB567062 A GB 567062A GB 1036125 A GB1036125 A GB 1036125A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cephalosporin
- aqueous solution
- purification
- adsorbing
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 229950008644 adicillin Drugs 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- MIFYHUACUWQUKT-GPUHXXMPSA-N penicillin N Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2[C@H](NC(=O)CCC[C@@H](N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-GPUHXXMPSA-N 0.000 abstract 1
- 238000012799 strong cation exchange Methods 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5670/62A GB1036125A (en) | 1962-02-14 | 1962-02-14 | Process for the purification of cephalosporin c |
FR924396A FR1353113A (fr) | 1962-02-14 | 1963-02-11 | Purification de la céphalosporine c |
SE157363A SE314773B (enrdf_load_stackoverflow) | 1962-02-14 | 1963-02-13 | |
DE1492049A DE1492049C3 (de) | 1962-02-14 | 1963-02-13 | Verfahren zur Gewinnung von Cephalosporin C aus einem dieses Antibiotikum neben Cephalosporin N enthaltenden fermentierten Medium |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5670/62A GB1036125A (en) | 1962-02-14 | 1962-02-14 | Process for the purification of cephalosporin c |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1036125A true GB1036125A (en) | 1966-07-13 |
Family
ID=9800446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5670/62A Expired GB1036125A (en) | 1962-02-14 | 1962-02-14 | Process for the purification of cephalosporin c |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB1036125A (enrdf_load_stackoverflow) |
SE (1) | SE314773B (enrdf_load_stackoverflow) |
-
1962
- 1962-02-14 GB GB5670/62A patent/GB1036125A/en not_active Expired
-
1963
- 1963-02-13 SE SE157363A patent/SE314773B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE314773B (enrdf_load_stackoverflow) | 1969-09-15 |
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