GB1025799A - 2-phenylcyclopropylguanidine - Google Patents

2-phenylcyclopropylguanidine

Info

Publication number
GB1025799A
GB1025799A GB1097064A GB1097064A GB1025799A GB 1025799 A GB1025799 A GB 1025799A GB 1097064 A GB1097064 A GB 1097064A GB 1097064 A GB1097064 A GB 1097064A GB 1025799 A GB1025799 A GB 1025799A
Authority
GB
United Kingdom
Prior art keywords
acid addition
amine
reaction
compound
phenylcyclopropylguanidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1097064A
Inventor
Joachim Augstein
Peter Rodway Leeming
Alastair Macleod Monro
Thomas Ian Wrigley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB1097064A priority Critical patent/GB1025799A/en
Publication of GB1025799A publication Critical patent/GB1025799A/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises 2-phenylcyclopropylguanidine, and pharmaceutically acceptable acid addition salts thereof. The compound may be prepared from 2-phenylcyclopropylamine by (a) cyanamide or dicyandiamide, or (b) reaction of the amine with an S-alkyl-isothiouronium acid addition salt, or (c) reaction of the amine with an acid addition salt of 1-amidino-3,5-dimethylpyrazole. Pharmaceutical compositions having anti-hypertensive activity, for oral or parenteral administration, comprise a compound of the invention together with a pharmaceutical carrier. The compositions may be in the form of tablets, capsules, elixirs, suspensions, and solutions.
GB1097064A 1964-03-16 1964-03-16 2-phenylcyclopropylguanidine Expired GB1025799A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1097064A GB1025799A (en) 1964-03-16 1964-03-16 2-phenylcyclopropylguanidine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1097064A GB1025799A (en) 1964-03-16 1964-03-16 2-phenylcyclopropylguanidine

Publications (1)

Publication Number Publication Date
GB1025799A true GB1025799A (en) 1966-04-14

Family

ID=9977670

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1097064A Expired GB1025799A (en) 1964-03-16 1964-03-16 2-phenylcyclopropylguanidine

Country Status (1)

Country Link
GB (1) GB1025799A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3456009A (en) * 1966-08-31 1969-07-15 Smithkline Corp Beta-lower alkoxyphenethylguanidine salts

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3456009A (en) * 1966-08-31 1969-07-15 Smithkline Corp Beta-lower alkoxyphenethylguanidine salts

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