GB1022861A - Substituted 3-pyrazolidinones - Google Patents

Substituted 3-pyrazolidinones

Info

Publication number
GB1022861A
GB1022861A GB1358661A GB1358661A GB1022861A GB 1022861 A GB1022861 A GB 1022861A GB 1358661 A GB1358661 A GB 1358661A GB 1358661 A GB1358661 A GB 1358661A GB 1022861 A GB1022861 A GB 1022861A
Authority
GB
United Kingdom
Prior art keywords
aralkyl
alkyl
aryl
organic solvent
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1358661A
Inventor
Bruno John Robert Nicholaus
Emilio Testa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Priority to GB1358661A priority Critical patent/GB1022861A/en
Priority to CH419162A priority patent/CH425804A/en
Priority to BE616418A priority patent/BE616418A/en
Publication of GB1022861A publication Critical patent/GB1022861A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of formula <FORM:1022861/C2/1> where R is alkyl, aryl or aralkyl, R1 is alkyl of at least 2 carbon atoms, aryl or aralkyl, and R2 and R3 are alkyl, monocyclic aryl or aralkyl or both are hydrogen; and their preparation by heating an a ,a -R,R1-b -propiolactone with a solution of a hydrogen halide in an inert organic solvent to obtain an a ,a -R,R1-b -halopropionic acid converting this to the acid halide or ester, which is then refluxed with a hydrazine R2NH.NHR3 optionally in the presence of a proton acceptor in an anhydrous organic solvent; the products may be N-alkylated.
GB1358661A 1961-04-14 1961-04-14 Substituted 3-pyrazolidinones Expired GB1022861A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB1358661A GB1022861A (en) 1961-04-14 1961-04-14 Substituted 3-pyrazolidinones
CH419162A CH425804A (en) 1961-04-14 1962-04-05 Process for the preparation of new pharmacologically active pyrazolidones
BE616418A BE616418A (en) 1961-04-14 1962-04-13 Pyrazolidinone compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1358661A GB1022861A (en) 1961-04-14 1961-04-14 Substituted 3-pyrazolidinones

Publications (1)

Publication Number Publication Date
GB1022861A true GB1022861A (en) 1966-03-16

Family

ID=10025668

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1358661A Expired GB1022861A (en) 1961-04-14 1961-04-14 Substituted 3-pyrazolidinones

Country Status (3)

Country Link
BE (1) BE616418A (en)
CH (1) CH425804A (en)
GB (1) GB1022861A (en)

Also Published As

Publication number Publication date
BE616418A (en) 1962-07-31
CH425804A (en) 1966-12-15

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