GB1011984A - Heterocyclic aminochloro compounds - Google Patents
Heterocyclic aminochloro compoundsInfo
- Publication number
- GB1011984A GB1011984A GB3478962A GB3478962A GB1011984A GB 1011984 A GB1011984 A GB 1011984A GB 3478962 A GB3478962 A GB 3478962A GB 3478962 A GB3478962 A GB 3478962A GB 1011984 A GB1011984 A GB 1011984A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aryl
- quinazolines
- arylamino
- morpholine
- chlorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
- C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Amino derivatives of heterocycles, defined as quinazolines, or quinazolines, pyrimidines and 1,3,5-triazines containing an aryl radical, which heterocycles contain one or two <FORM:1011984/C2/1> in which R1 is hydrogen or aryl, R2 is morpholino or aryl, R3 is chlorine, morpholine, aryl, arylamino, R4 is morpholine, aryl, arylamino, and the carbocyclic rings in the above formulae may be chlorine or methoxy substituted. Specified diluents preferred are water miscible, e.g. aliphatic ketones, cyclic ethers such as dioxan, groupings and wherein the amino groups are attached to a carboxylic ring, are produced by hydrogenating the corresponding nitro derivatives in a solvent or diluent in the presence of Raney nickel catalyst and of tertiary amines or stoically hindered secondary amines, the amount of hydrogen absorbed being that required to convert a nitro into an amino group, the hydrogenation being preferably conducted at 10 DEG to 50 DEG C. Per se are claimed compounds of the general Formula I to VII: <FORM:1011984/C2/2> tetrahydrofuran, which may also contain water. Numerous detailed working examples of the process and named products are given. Specification 927,974 is referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEB63992A DE1172266B (en) | 1961-09-13 | 1961-09-13 | Process for the preparation of amino-chloro derivatives of heterocycles |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1011984A true GB1011984A (en) | 1965-12-01 |
Family
ID=6974215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3478962A Expired GB1011984A (en) | 1961-09-13 | 1962-09-12 | Heterocyclic aminochloro compounds |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH411902A (en) |
DE (1) | DE1172266B (en) |
GB (1) | GB1011984A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI70036C (en) * | 1980-01-31 | 1986-09-12 | Ciba Geigy Ag | CHROMOGENE QUINAZOLINE INFOERING |
-
1961
- 1961-09-13 DE DEB63992A patent/DE1172266B/en active Pending
-
1962
- 1962-08-14 CH CH974762A patent/CH411902A/en unknown
- 1962-09-12 GB GB3478962A patent/GB1011984A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1172266B (en) | 1964-06-18 |
CH411902A (en) | 1966-04-30 |
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