GB1011551A - Improvements in or relating to 5-amino-1,5-diazacyclooctanes - Google Patents

Improvements in or relating to 5-amino-1,5-diazacyclooctanes

Info

Publication number
GB1011551A
GB1011551A GB4619661A GB4619661A GB1011551A GB 1011551 A GB1011551 A GB 1011551A GB 4619661 A GB4619661 A GB 4619661A GB 4619661 A GB4619661 A GB 4619661A GB 1011551 A GB1011551 A GB 1011551A
Authority
GB
United Kingdom
Prior art keywords
compounds
diazacyclooctanes
amino
alkyl
reduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4619661A
Inventor
Ernst Jucker
Adolf Johann Lindenmann
John Gmunder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Sandoz AG
Original Assignee
Sandoz Patent Ltd
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH146161A external-priority patent/CH383393A/en
Application filed by Sandoz Patent Ltd, Sandoz AG filed Critical Sandoz Patent Ltd
Publication of GB1011551A publication Critical patent/GB1011551A/en
Expired legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of general formula <FORM:1011551/C2/1> in which R is alkyl (1-4 C), hydroxyalkyl (1-4 C) or aralkyl (7-10 C); and their acid addition salts; and their preparation by reduction by known methods of corresponding 5-nitroso compounds, themselves obtainable by nitrosylation by known methods of the 5-unsubstituted compounds. N-R- 1,5-Diazacyclooctanes are obtainable by the reduction of quaternary compounds of general formula <FORM:1011551/C2/2> which result from the reaction of 1,2 -trimethylenepyrazolidine with compounds R-halogen or of a trimethylene dihalide with a compound RNHNH2. N - Alkyl - N1 - (3 - sulphamyl - 4 - chlorobenzoyl - amino - 1,5 - diazacyclooctanes are said to be obtained from compounds I on reaction with an appropriate benzoyl halide.
GB4619661A 1961-02-08 1961-12-27 Improvements in or relating to 5-amino-1,5-diazacyclooctanes Expired GB1011551A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH146161A CH383393A (en) 1961-02-08 1961-02-08 Process for the preparation of new heterocyclic compounds
CH1415661A CH393342A (en) 1961-02-08 1961-12-06 Process for the preparation of a new heterocyclic compound

Publications (1)

Publication Number Publication Date
GB1011551A true GB1011551A (en) 1965-12-01

Family

ID=25687719

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4619661A Expired GB1011551A (en) 1961-02-08 1961-12-27 Improvements in or relating to 5-amino-1,5-diazacyclooctanes

Country Status (2)

Country Link
CH (1) CH393342A (en)
GB (1) GB1011551A (en)

Also Published As

Publication number Publication date
CH393342A (en) 1965-06-15

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