GB1008583A - Controlled release medicaments - Google Patents

Controlled release medicaments

Info

Publication number
GB1008583A
GB1008583A GB1?823/62A GB182362A GB1008583A GB 1008583 A GB1008583 A GB 1008583A GB 182362 A GB182362 A GB 182362A GB 1008583 A GB1008583 A GB 1008583A
Authority
GB
United Kingdom
Prior art keywords
mixture
medicament
enzyme
vehicle
controlled release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1?823/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olin Corp
Original Assignee
Olin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olin Corp filed Critical Olin Corp
Publication of GB1008583A publication Critical patent/GB1008583A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

A controlled release composition comprises a medicament and a pharmaceutically acceptable vehicle mixed with or dissolving the medicament, the vehicle being susceptible to the digestive action of an enzyme or mixture of enzymes, and the composition containing an enzyme or mixture of ensymes which is capable of digesting the vehicle. Two or more substrate/enzyme combinations may be employed in a dosage unit in order to obtain release of medicament over a period of time in a changing environment. Thus, a mixture of starch diastase, lipase and tristearin, with or without the further addition of gelatin and gelatinase, in the form of a tablet will allow an added drug such as a sulphonamide to be released in both the stomach and the intestine. The composition may take the form of an emulsion, suspension, tablet (oral, sublingual, buccal or vaginal), capsule, ointment or suppository. Lists of drugs, enzymes and substrates are included.
GB1?823/62A 1961-04-25 1962-04-17 Controlled release medicaments Expired GB1008583A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10529861A 1961-04-25 1961-04-25

Publications (1)

Publication Number Publication Date
GB1008583A true GB1008583A (en) 1965-10-27

Family

ID=22305062

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1?823/62A Expired GB1008583A (en) 1961-04-25 1962-04-17 Controlled release medicaments

Country Status (3)

Country Link
BR (1) BR6238314D0 (en)
FR (1) FR2664M (en)
GB (1) GB1008583A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989544A (en) * 1989-05-16 1999-11-23 Block Drug Company, Inc. Composition and method for reducing gastro-intestinal distress due to alpha-D-galactoside-linked/containing sugars
US6598371B1 (en) 1998-10-06 2003-07-29 Stanelco Fibre Optics Ltd. Capsules
DE102005049649A1 (en) * 2005-10-18 2007-04-19 Pro Natura Gesellschaft für gesunde Ernährung mbH Composition, useful as e.g. nutritional supplement for the relief of gastro-intestinal tract complaints due to uptake of food containing oligosaccharide, comprises a combination of alpha-galactosidase and beta-fructofuraonosidase

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2051483A1 (en) * 1969-05-19 1971-04-09 Midy Centre Rech M Proteolytic enzymes for treating throat - infections

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989544A (en) * 1989-05-16 1999-11-23 Block Drug Company, Inc. Composition and method for reducing gastro-intestinal distress due to alpha-D-galactoside-linked/containing sugars
US6344196B1 (en) 1989-05-16 2002-02-05 Block Drug Company, Inc. Compositions and method for reducing gastro-intestinal distress due to alpha-d-galactoside-linked/containing sugars
US6598371B1 (en) 1998-10-06 2003-07-29 Stanelco Fibre Optics Ltd. Capsules
DE102005049649A1 (en) * 2005-10-18 2007-04-19 Pro Natura Gesellschaft für gesunde Ernährung mbH Composition, useful as e.g. nutritional supplement for the relief of gastro-intestinal tract complaints due to uptake of food containing oligosaccharide, comprises a combination of alpha-galactosidase and beta-fructofuraonosidase

Also Published As

Publication number Publication date
BR6238314D0 (en) 1973-05-24
FR2664M (en) 1964-07-20

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