GB1006887A - Improvements in or relating to phenylalkyl- and phenylcyclopropylsulfamides - Google Patents
Improvements in or relating to phenylalkyl- and phenylcyclopropylsulfamidesInfo
- Publication number
- GB1006887A GB1006887A GB35156/63A GB3515663A GB1006887A GB 1006887 A GB1006887 A GB 1006887A GB 35156/63 A GB35156/63 A GB 35156/63A GB 3515663 A GB3515663 A GB 3515663A GB 1006887 A GB1006887 A GB 1006887A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- acyl
- group
- piperazino
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BDNNTMPFJZHCAC-UHFFFAOYSA-N [cyclopropyl(sulfamoyl)amino]benzene Chemical class C=1C=CC=CC=1N(S(=O)(=O)N)C1CC1 BDNNTMPFJZHCAC-UHFFFAOYSA-N 0.000 title 1
- -1 aminophenyl Chemical group 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001412 amines Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 2
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 2
- 125000006557 (C2-C5) alkylene group Chemical group 0.000 abstract 1
- 125000003047 N-acetyl group Chemical group 0.000 abstract 1
- 235000019483 Peanut oil Nutrition 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical class [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000004464 hydroxyphenyl group Chemical group 0.000 abstract 1
- 239000007937 lozenge Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- AOTWIFLKURJQGE-UHFFFAOYSA-N n-cyclopropylaniline Chemical compound C1CC1NC1=CC=CC=C1 AOTWIFLKURJQGE-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000004006 olive oil Substances 0.000 abstract 1
- 235000008390 olive oil Nutrition 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000312 peanut oil Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000008159 sesame oil Substances 0.000 abstract 1
- 235000011803 sesame oil Nutrition 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- NVBFHJWHLNUMCV-UHFFFAOYSA-N sulfamide Chemical compound NS(N)(=O)=O NVBFHJWHLNUMCV-UHFFFAOYSA-N 0.000 abstract 1
- QAHVHSLSRLSVGS-UHFFFAOYSA-N sulfamoyl chloride Chemical compound NS(Cl)(=O)=O QAHVHSLSRLSVGS-UHFFFAOYSA-N 0.000 abstract 1
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/08—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US223826A US3143549A (en) | 1962-09-14 | 1962-09-14 | Phenylalkylsulfamides |
| US242651A US3147305A (en) | 1962-09-14 | 1962-12-06 | 2-phenylcyclopropylsulfamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1006887A true GB1006887A (en) | 1965-10-06 |
Family
ID=26918166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35156/63A Expired GB1006887A (en) | 1962-09-14 | 1963-09-05 | Improvements in or relating to phenylalkyl- and phenylcyclopropylsulfamides |
Country Status (6)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0860428A3 (en) * | 1997-02-04 | 2000-07-19 | Eli Lilly And Company | Sulphonamide derivatives |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3267139A (en) * | 1963-09-24 | 1966-08-16 | Smith Kline French Lab | Nu'-trimethylacetyl-nu-phenylalkyl-sulfamides and-phenylcyclopropylsulfamides |
| US3336382A (en) * | 1964-02-11 | 1967-08-15 | Allied Chem | Diarylsulfamyl fluorides and tetraarylsulfamides |
| US4350685A (en) * | 1981-02-06 | 1982-09-21 | Smithkline Corporation | Antiallergic imidodisulfamides |
| DE3204168A1 (de) * | 1982-02-06 | 1983-08-11 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von sulfonamiden |
| SE527101C2 (sv) * | 2004-05-19 | 2005-12-20 | Volvo Lastvagnar Ab | Magnetbrytararrangemang och förfarande för att erhålla en differentialmagnetbrytare |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2173056A (en) * | 1938-06-11 | 1939-09-12 | Du Pont | Dyes for cellulose esters and ethers |
| US2173054A (en) * | 1938-06-11 | 1939-09-12 | Du Pont | Monazo dyes for cellulose esters and ethers |
| AT214703B (de) * | 1948-05-18 | Exxon Research Engineering Co | Verfahren zur Bekämpfung von Schädlingen | |
| DE947554C (de) * | 1953-09-18 | 1956-08-16 | Farbenwerke Hoechst Ag Vormals | Verfahren zur Herstellung von Derivaten des Sulfamids |
| NL89282C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1954-05-14 | |||
| GB789273A (en) * | 1955-04-07 | 1958-01-15 | Bayer Ag | Trichloro-methyl-mercaptan derivatives and production |
| US2867658A (en) * | 1956-05-18 | 1959-01-06 | Geigy Ag J R | Halo substituted sulfanilides |
| US3041336A (en) * | 1958-10-01 | 1962-06-26 | Norwich Pharma Co | 3-oxo-1.2.6-thiadiazine-1.1-dioxides |
| US3068283A (en) * | 1960-12-05 | 1962-12-11 | Smith Kline French Lab | (2-phenylcyclopropyl)-ureas, and 2-phenylcyclopropylcarbamoylamines |
-
1962
- 1962-12-06 US US242651A patent/US3147305A/en not_active Expired - Lifetime
-
1963
- 1963-08-13 SE SE8865/63A patent/SE314671B/xx unknown
- 1963-08-13 DK DK385763AA patent/DK115325B/da unknown
- 1963-09-05 GB GB35156/63A patent/GB1006887A/en not_active Expired
- 1963-09-06 CH CH1105563A patent/CH447144A/fr unknown
- 1963-12-09 FR FR956505A patent/FR3293M/fr active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0860428A3 (en) * | 1997-02-04 | 2000-07-19 | Eli Lilly And Company | Sulphonamide derivatives |
| US6303816B1 (en) | 1997-02-04 | 2001-10-16 | Eli Lilly And Company | Sulphonamide derivatives |
| US6596716B2 (en) | 1997-02-04 | 2003-07-22 | Eli Lilly And Company | 2-propane-sulphonamide derivatives |
| US7135487B2 (en) | 1997-02-04 | 2006-11-14 | Eli Lilly And Company | Sulphonamide derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| FR3293M (fr) | 1965-05-03 |
| US3147305A (en) | 1964-09-01 |
| CH447144A (fr) | 1967-11-30 |
| SE314671B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-09-15 |
| DK115325B (da) | 1969-09-29 |
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