GB1004582A - Chloroaromatic sulphonamides - Google Patents
Chloroaromatic sulphonamidesInfo
- Publication number
- GB1004582A GB1004582A GB28172/64A GB2817264A GB1004582A GB 1004582 A GB1004582 A GB 1004582A GB 28172/64 A GB28172/64 A GB 28172/64A GB 2817264 A GB2817264 A GB 2817264A GB 1004582 A GB1004582 A GB 1004582A
- Authority
- GB
- United Kingdom
- Prior art keywords
- halogen atom
- sulphonamides
- hydrogen
- methyl group
- bromanilide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises sulphonamides of the formula <FORM:1004582/C2/1> in which (a) R1 is hydrogen and R2 is a halogen atom or a methyl group or (b) R1 is a halogen atom or a methyl group and R2 is hydrogen or a halogen atom. The invention comprises also salts of the sulphonamides. The compounds may be prepared by reacting 3,4-dichlorobenzene sulphonic acid chloride with an appropriately substituted aniline at atmospheric temperature in an aqueous medium in the presence of an acid-binding agent or in a non-polar organic solvent. The examples describe the preparation of the 3- and 4-chloranilide, the m- and p-toluidide, the 3-methyl-4-bromanilide and the 4-bromanilide of 3,4-dichlorobenzene sulphoric acid. The products are useful as bacteriostats and fungistats (see Division A5).ALSO:Bacteriostats and fungistats for medicinal or veterinary use contain sulphonamides of the formula <FORM:1004582/A5-A6/1> in which (a) R1 is hydrogen and R2 is a halogen atom or a methyl group or (b) R1 is a halogen atom or a methyl group and R2 is hydrogen or a halogen atom (see Division C2). Salts of the sulphonamides may also be used. Specified compounds are the 3- and 4-chloranilide, the m- and p-toluidide, the 3-methyl-4-brom-anilide and the 4-bromanilide of 3, 4-dichlorobenzene sulphonic acid. The products may be formulated as compositions for oral, parenteral or topical use and may be put up as tablets, coated pills, suspensions, solutions, granules, capsules, emulsions, powders and ointments with the aid of known pharmaceutical diluents. Other pharmaceutical products may be included in the compositions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUCI000467 | 1963-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1004582A true GB1004582A (en) | 1965-09-15 |
Family
ID=10994310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB28172/64A Expired GB1004582A (en) | 1963-08-24 | 1964-07-08 | Chloroaromatic sulphonamides |
Country Status (7)
Country | Link |
---|---|
AT (1) | AT247306B (en) |
DE (1) | DE1217949B (en) |
DK (1) | DK117893B (en) |
FI (1) | FI43185C (en) |
FR (2) | FR4392M (en) |
GB (1) | GB1004582A (en) |
NL (1) | NL142155B (en) |
-
1964
- 1964-07-08 GB GB28172/64A patent/GB1004582A/en not_active Expired
- 1964-08-03 AT AT667964A patent/AT247306B/en active
- 1964-08-04 DE DEC33563A patent/DE1217949B/en active Pending
- 1964-08-11 FR FR984870A patent/FR4392M/fr not_active Expired
- 1964-08-11 FR FR984871A patent/FR1411827A/en not_active Expired
- 1964-08-12 FI FI172664A patent/FI43185C/en active
- 1964-08-21 DK DK415364A patent/DK117893B/en unknown
- 1964-08-21 NL NL6409737A patent/NL142155B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK117893B (en) | 1970-06-15 |
NL142155B (en) | 1974-05-15 |
FR1411827A (en) | 1965-09-24 |
FI43185B (en) | 1970-11-02 |
FR4392M (en) | 1966-09-05 |
NL6409737A (en) | 1965-02-25 |
FI43185C (en) | 1971-02-10 |
DE1217949B (en) | 1966-06-02 |
AT247306B (en) | 1966-06-10 |
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