GB1000891A - Improvements in or relating to substituted 2,8-diazaspiro[4,5]decanes - Google Patents
Improvements in or relating to substituted 2,8-diazaspiro[4,5]decanesInfo
- Publication number
- GB1000891A GB1000891A GB35477/61A GB3547761A GB1000891A GB 1000891 A GB1000891 A GB 1000891A GB 35477/61 A GB35477/61 A GB 35477/61A GB 3547761 A GB3547761 A GB 3547761A GB 1000891 A GB1000891 A GB 1000891A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- benzyl
- formula
- halo
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WYZZNMWIWHRXRM-UHFFFAOYSA-N 2,8-diazaspiro[4.5]decane Chemical class C1NCCC21CCNCC2 WYZZNMWIWHRXRM-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- KZNICNPSHKQLFF-UHFFFAOYSA-N succinimide Chemical compound O=C1CCC(=O)N1 KZNICNPSHKQLFF-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005283 haloketone group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- SJZKULRDWHPHGG-UHFFFAOYSA-N 1-benzylpiperidin-4-one Chemical compound C1CC(=O)CCN1CC1=CC=CC=C1 SJZKULRDWHPHGG-UHFFFAOYSA-N 0.000 abstract 1
- FUHGFUBJUUFMSF-UHFFFAOYSA-N 4-chloro-1-(4-methylphenyl)butan-1-one Chemical compound CC1=CC=C(C(=O)CCCCl)C=C1 FUHGFUBJUUFMSF-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- MLIREBYILWEBDM-UHFFFAOYSA-N anhydrous cyanoacetic acid Natural products OC(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229960002317 succinimide Drugs 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1213560A CH392534A (de) | 1960-10-31 | 1960-10-31 | Verfahren zur Herstellung neuer heterocyclischer Verbindungen |
| CH747161 | 1961-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1000891A true GB1000891A (en) | 1965-08-11 |
Family
ID=25701417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35477/61A Expired GB1000891A (en) | 1960-10-31 | 1961-10-02 | Improvements in or relating to substituted 2,8-diazaspiro[4,5]decanes |
Country Status (7)
| Country | Link |
|---|---|
| CY (1) | CY383A (cg-RX-API-DMAC7.html) |
| ES (1) | ES271677A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR1742M (cg-RX-API-DMAC7.html) |
| GB (1) | GB1000891A (cg-RX-API-DMAC7.html) |
| LU (1) | LU40767A1 (cg-RX-API-DMAC7.html) |
| MY (1) | MY6700073A (cg-RX-API-DMAC7.html) |
| OA (1) | OA00712A (cg-RX-API-DMAC7.html) |
-
1961
- 1961-10-02 GB GB35477/61A patent/GB1000891A/en not_active Expired
- 1961-10-30 LU LU40767A patent/LU40767A1/xx unknown
- 1961-10-31 ES ES0271677A patent/ES271677A1/es not_active Expired
-
1962
- 1962-01-29 FR FR886272A patent/FR1742M/fr not_active Expired
-
1964
- 1964-12-08 OA OA50784A patent/OA00712A/xx unknown
-
1967
- 1967-04-13 CY CY38367A patent/CY383A/xx unknown
- 1967-12-31 MY MY196773A patent/MY6700073A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1742M (fr) | 1963-03-25 |
| MY6700073A (en) | 1967-12-31 |
| ES271677A1 (es) | 1962-06-16 |
| CY383A (en) | 1967-04-13 |
| LU40767A1 (cg-RX-API-DMAC7.html) | 1962-04-30 |
| OA00712A (fr) | 1967-07-15 |
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