GB0218830D0 - Anaesthetic conjugate - Google Patents

Anaesthetic conjugate

Info

Publication number
GB0218830D0
GB0218830D0 GBGB0218830.8A GB0218830A GB0218830D0 GB 0218830 D0 GB0218830 D0 GB 0218830D0 GB 0218830 A GB0218830 A GB 0218830A GB 0218830 D0 GB0218830 D0 GB 0218830D0
Authority
GB
United Kingdom
Prior art keywords
anaesthetic
conjugate
anaesthetic conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0218830.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenix Ltd
Original Assignee
Syngenix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenix Ltd filed Critical Syngenix Ltd
Priority to GBGB0218830.8A priority Critical patent/GB0218830D0/en
Publication of GB0218830D0 publication Critical patent/GB0218830D0/en
Priority to PCT/GB2003/003525 priority patent/WO2004014350A2/en
Priority to AU2003267540A priority patent/AU2003267540A1/en
Priority to AU2003267542A priority patent/AU2003267542A1/en
Priority to PCT/GB2003/003522 priority patent/WO2004014973A2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
GBGB0218830.8A 2002-08-13 2002-08-13 Anaesthetic conjugate Ceased GB0218830D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB0218830.8A GB0218830D0 (en) 2002-08-13 2002-08-13 Anaesthetic conjugate
PCT/GB2003/003525 WO2004014350A2 (en) 2002-08-13 2003-08-13 Polymer conjugates of a local anaesthetic drug
AU2003267540A AU2003267540A1 (en) 2002-08-13 2003-08-13 Biodegradable polymer
AU2003267542A AU2003267542A1 (en) 2002-08-13 2003-08-13 Polymer conjugates of a local anaesthetic drug
PCT/GB2003/003522 WO2004014973A2 (en) 2002-08-13 2003-08-13 Biodegradable polymer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0218830.8A GB0218830D0 (en) 2002-08-13 2002-08-13 Anaesthetic conjugate

Publications (1)

Publication Number Publication Date
GB0218830D0 true GB0218830D0 (en) 2002-09-18

Family

ID=9942247

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0218830.8A Ceased GB0218830D0 (en) 2002-08-13 2002-08-13 Anaesthetic conjugate

Country Status (3)

Country Link
AU (1) AU2003267542A1 (en)
GB (1) GB0218830D0 (en)
WO (1) WO2004014350A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003267540A1 (en) * 2002-08-13 2004-02-25 Sirus Pharmaceuticals Ltd Biodegradable polymer
WO2009054916A2 (en) * 2007-10-19 2009-04-30 Nektar Therapeutics Al, Corporation Oligomer conjugates of lidocaine and its derivatives
CN106310289B (en) * 2015-06-24 2020-10-13 天津键凯科技有限公司 Conjugate of polyethylene glycol and anesthetic and preparation method thereof
CN107789628B (en) * 2016-12-29 2021-07-23 天津键凯科技有限公司 Application of conjugate of polyethylene glycol and local anesthetic in non-anesthesia analgesia
WO2019109065A1 (en) * 2017-12-01 2019-06-06 The Children's Medical Center Corporation Covalent anesthetic-polymer conjugates for prolonged local anesthesia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE448203B (en) * 1980-09-10 1987-02-02 Johan Alfred Olof Johansson  FORM BODY MANUFACTURED FROM AGAR AND / OR AGAROS AND / OR A DERIVATIVE THEREOF CONTAINING PHARMACOLOGICALLY ACTIVE SUBSTANCE
US4636387A (en) * 1982-06-21 1987-01-13 Research Corporation Anesthetic polyorganophosphazenes
US4650771A (en) * 1983-11-04 1987-03-17 Miles Laboratories, Inc. Immunogens, antibodies, labeled conjugates, and related derivatives for lidocaine and analogs thereof
AU2001280597A1 (en) * 2000-07-17 2002-01-30 Guilford Pharmaceuticals Inc. Compositions for sustained release of analgesic agents, and methods of making and using the same
DE10112825A1 (en) * 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylation of active ingredients in aqueous solution
AU2003267540A1 (en) * 2002-08-13 2004-02-25 Sirus Pharmaceuticals Ltd Biodegradable polymer
GB0218827D0 (en) * 2002-08-13 2002-09-18 Syngenix Ltd Anaesthetic compounds and conjugates thereof

Also Published As

Publication number Publication date
AU2003267542A8 (en) 2004-02-25
WO2004014350A2 (en) 2004-02-19
AU2003267542A1 (en) 2004-02-25
WO2004014350A3 (en) 2004-10-07

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)