GB0218827D0 - Anaesthetic compounds and conjugates thereof - Google Patents

Anaesthetic compounds and conjugates thereof

Info

Publication number
GB0218827D0
GB0218827D0 GBGB0218827.4A GB0218827A GB0218827D0 GB 0218827 D0 GB0218827 D0 GB 0218827D0 GB 0218827 A GB0218827 A GB 0218827A GB 0218827 D0 GB0218827 D0 GB 0218827D0
Authority
GB
United Kingdom
Prior art keywords
conjugates
anaesthetic compounds
anaesthetic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0218827.4A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenix Ltd
Original Assignee
Syngenix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenix Ltd filed Critical Syngenix Ltd
Priority to GBGB0218827.4A priority Critical patent/GB0218827D0/en
Publication of GB0218827D0 publication Critical patent/GB0218827D0/en
Priority to PCT/GB2003/003527 priority patent/WO2004014841A1/en
Priority to AU2003267543A priority patent/AU2003267543A1/en
Priority to AU2003267540A priority patent/AU2003267540A1/en
Priority to PCT/GB2003/003522 priority patent/WO2004014973A2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB0218827.4A 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof Ceased GB0218827D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB0218827.4A GB0218827D0 (en) 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof
PCT/GB2003/003527 WO2004014841A1 (en) 2002-08-13 2003-08-13 Compounds, pro-drugs and conjugates derived from mexiletine
AU2003267543A AU2003267543A1 (en) 2002-08-13 2003-08-13 Compounds, pro-drugs and conjugates derived from mexiletine
AU2003267540A AU2003267540A1 (en) 2002-08-13 2003-08-13 Biodegradable polymer
PCT/GB2003/003522 WO2004014973A2 (en) 2002-08-13 2003-08-13 Biodegradable polymer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0218827.4A GB0218827D0 (en) 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof

Publications (1)

Publication Number Publication Date
GB0218827D0 true GB0218827D0 (en) 2002-09-18

Family

ID=9942244

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0218827.4A Ceased GB0218827D0 (en) 2002-08-13 2002-08-13 Anaesthetic compounds and conjugates thereof

Country Status (3)

Country Link
AU (1) AU2003267543A1 (en)
GB (1) GB0218827D0 (en)
WO (1) WO2004014841A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004014973A2 (en) * 2002-08-13 2004-02-19 Sirus Pharmaceuticals Ltd Biodegradable polymer
GB0218830D0 (en) * 2002-08-13 2002-09-18 Syngenix Ltd Anaesthetic conjugate
US20100303753A1 (en) * 2007-10-19 2010-12-02 Nektar Therapeutics Oligomer Conjugates of Lidocaine and Its Derivatives
JP2012530764A (en) * 2009-06-24 2012-12-06 シャイア エルエルシー Amino acid and peptide prodrugs of mexiletine and uses thereof
BR102013020313B1 (en) * 2013-08-09 2021-07-06 Fundação Oswaldo Cruz biphenyloxy-alkyl-amines and aryloxy-alkyl-amine derivatives, and pharmaceutical composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643240A1 (en) * 1966-09-16 1971-06-24 Boehringer Sohn Ingelheim Process for the preparation of new racemic or optically active 1-phenoxy-2-aminoalkanes
US5985933A (en) * 1997-01-24 1999-11-16 Celgene Corporation Methods for treating central and peripheral nerve pain
CA2232147A1 (en) * 1997-04-03 1998-10-03 F. Hoffmann-La Roche Ag Phenoxymethyl piperidine derivatives
US6413507B1 (en) * 1999-12-23 2002-07-02 Shearwater Corporation Hydrolytically degradable carbamate derivatives of poly (ethylene glycol)

Also Published As

Publication number Publication date
WO2004014841A1 (en) 2004-02-19
AU2003267543A1 (en) 2004-02-25

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)