GB0001794D0 - Amphiphilic polysaccharide derivatives - Google Patents

Amphiphilic polysaccharide derivatives

Info

Publication number
GB0001794D0
GB0001794D0 GBGB0001794.7A GB0001794A GB0001794D0 GB 0001794 D0 GB0001794 D0 GB 0001794D0 GB 0001794 A GB0001794 A GB 0001794A GB 0001794 D0 GB0001794 D0 GB 0001794D0
Authority
GB
United Kingdom
Prior art keywords
polysaccharide derivatives
amphiphilic polysaccharide
amphiphilic
derivatives
polysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB0001794.7A
Other versions
GB2342357A (en
GB2342357B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediplex Corp Korea
Original Assignee
Mediplex Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019990014003A external-priority patent/KR100314496B1/en
Application filed by Mediplex Corp Korea filed Critical Mediplex Corp Korea
Publication of GB0001794D0 publication Critical patent/GB0001794D0/en
Publication of GB2342357A publication Critical patent/GB2342357A/en
Application granted granted Critical
Publication of GB2342357B publication Critical patent/GB2342357B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
GB0001794A 1998-05-28 1999-05-14 Amphiphilic heparin derivatives Expired - Fee Related GB2342357B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR19980019469 1998-05-28
KR1019990014003A KR100314496B1 (en) 1998-05-28 1999-04-20 Non-thrombogenic heparin derivatives, process for preparation and use thereof
US09/300,173 US6245753B1 (en) 1998-05-28 1999-04-27 Amphiphilic polysaccharide derivatives
PCT/KR1999/000242 WO1999061481A1 (en) 1998-05-28 1999-05-14 Amphiphilic polysaccharide derivatives

Publications (3)

Publication Number Publication Date
GB0001794D0 true GB0001794D0 (en) 2000-03-22
GB2342357A GB2342357A (en) 2000-04-12
GB2342357B GB2342357B (en) 2002-03-27

Family

ID=27349744

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0001794A Expired - Fee Related GB2342357B (en) 1998-05-28 1999-05-14 Amphiphilic heparin derivatives

Country Status (5)

Country Link
JP (1) JP3541007B2 (en)
AU (1) AU3735899A (en)
DE (1) DE19981169B4 (en)
GB (1) GB2342357B (en)
WO (1) WO1999061481A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656922B2 (en) * 1998-05-28 2003-12-02 Mediplex Corporation, Korea Oral delivery of macromolecules
US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US7303768B2 (en) 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
KR100378109B1 (en) * 2000-10-24 2003-03-29 주식회사 메디프렉스 Hydrophobic multicomponant heparin conjugates, a preparing method and a use thereof
EP1385530A4 (en) * 2001-05-09 2005-11-09 Mediplex Corp Formulation of amphiphilic heparin derivatives for enhancing mucosal absorption
US7145125B2 (en) 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
FR2864091B1 (en) * 2003-12-19 2006-04-07 Ethypharm Sa AMPHIPHILE HEPARIN DERIVATIVE FORMED BY COUPLING HEPARIN WITH A BILARY ACID
DE602005019582D1 (en) 2004-08-30 2010-04-08 Seo Hong Yoo NERVE PROTECTION OF UNLOCKED UDCA IN A FOKAL ISCHEMIC MODEL
CA2584184A1 (en) 2004-10-15 2006-04-27 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
US20110046050A1 (en) 2007-02-08 2011-02-24 Emisphere Technologies, Inc. Phenylalkylcarboxylic acid delivery agents
WO2009092151A1 (en) * 2007-12-05 2009-07-30 Xiao-Xia Zhu Amphiphilic polymers having a cholane core
US8759322B2 (en) 2008-11-05 2014-06-24 National University Corporation Tokyo Medical And Dental University Hyaluronic acid derivative and pharmaceutical composition thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB891554A (en) * 1959-10-19 1962-03-14 Applic Chimiques D Etudes Et D Galenic suppository containing salts of heparin
US3482014A (en) * 1966-06-29 1969-12-02 Canada Packers Ltd Orally active heparin and method for making and using same
AU8129894A (en) * 1993-11-01 1995-05-23 Alpha-Beta Technology, Inc. Derivatized polysaccharide bile acid sequestrant for reducing cholesterol
JPH07206903A (en) * 1994-01-24 1995-08-08 Takeda Chem Ind Ltd Aggregate of super molecule structure type

Also Published As

Publication number Publication date
GB2342357A (en) 2000-04-12
JP2002516355A (en) 2002-06-04
WO1999061481A1 (en) 1999-12-02
AU3735899A (en) 1999-12-13
JP3541007B2 (en) 2004-07-07
DE19981169B4 (en) 2007-09-13
GB2342357B (en) 2002-03-27
DE19981169T1 (en) 2000-11-16

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20110514