HK1042478A1 - 2-oxo-2h-quinoline derivatives - Google Patents

2-oxo-2h-quinoline derivatives

Info

Publication number
HK1042478A1
HK1042478A1 HK02102249.3A HK02102249A HK1042478A1 HK 1042478 A1 HK1042478 A1 HK 1042478A1 HK 02102249 A HK02102249 A HK 02102249A HK 1042478 A1 HK1042478 A1 HK 1042478A1
Authority
HK
Hong Kong
Prior art keywords
oxo
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
HK02102249.3A
Other languages
Chinese (zh)
Inventor
Gante Joachim
Juraszyk Horst
Wurziger Hanns
Dorsch Dieter
Buchstaller Hans-Peter
Bernotat-Danielowski Sabine
Melzer Guido
Anzali Soheila
Mederski Werner
Original Assignee
默克專利股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 默克專利股份公司 filed Critical 默克專利股份公司
Publication of HK1042478A1 publication Critical patent/HK1042478A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
HK02102249.3A 1998-08-29 2002-03-25 2-oxo-2h-quinoline derivatives HK1042478A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19839499A DE19839499A1 (en) 1998-08-29 1998-08-29 2-oxo-2H-quinoline derivatives
PCT/EP1999/005315 WO2000012479A1 (en) 1998-08-29 1999-07-26 2-oxo-2h-quinoline derivatives

Publications (1)

Publication Number Publication Date
HK1042478A1 true HK1042478A1 (en) 2002-08-16

Family

ID=7879227

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102249.3A HK1042478A1 (en) 1998-08-29 2002-03-25 2-oxo-2h-quinoline derivatives

Country Status (17)

Country Link
EP (1) EP1107954A1 (en)
JP (1) JP2002523494A (en)
KR (1) KR20010072862A (en)
CN (1) CN1315942A (en)
AR (1) AR021782A1 (en)
AU (1) AU5164199A (en)
BR (1) BR9913140A (en)
CA (1) CA2342230A1 (en)
DE (1) DE19839499A1 (en)
HK (1) HK1042478A1 (en)
HU (1) HUP0103212A3 (en)
ID (1) ID27863A (en)
NO (1) NO20010996L (en)
PL (1) PL346045A1 (en)
SK (1) SK2652001A3 (en)
WO (1) WO2000012479A1 (en)
ZA (1) ZA200102565B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1569912E (en) 2002-12-03 2015-09-15 Pharmacyclics Llc 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
SG10201900631TA (en) 2014-08-01 2019-02-27 Nuevolution As Compounds active towards bromodomains

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use
IE43079B1 (en) * 1975-03-20 1980-12-17 Ici Ltd Quinolone derivatives
JPS596858B2 (en) * 1975-04-30 1984-02-15 オオツカセイヤク カブシキガイシヤ Method for producing 3,4-dihydrocarbostyryl derivative
AT347956B (en) * 1976-03-18 1979-01-25 Ici Ltd Process for the preparation of new quinol-2-on-4-yl-alkanoic acids and their base addition salts
DE2651581A1 (en) * 1976-11-12 1978-05-18 Merck Patent Gmbh CHINOLONE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
WO1992004328A1 (en) * 1990-09-07 1992-03-19 Schering Corporation Antiviral compounds and antihypertensive compounds
ATE161252T1 (en) * 1990-09-07 1998-01-15 Schering Corp ANTIVIRAL AND ANTIHYPERTENSIVE COMPOUNDS
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
DE4208304A1 (en) * 1992-03-16 1993-09-23 Merck Patent Gmbh 2-OXOCHINOLINDERIVATE
IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
US5612353A (en) * 1995-06-07 1997-03-18 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds
DE19528418A1 (en) * 1995-08-02 1997-02-06 Merck Patent Gmbh Endothelin receptor antagonists
DE19530996A1 (en) * 1995-08-23 1997-02-27 Boehringer Mannheim Gmbh Cyclic guanidines, process for their preparation and pharmaceuticals
US5968959A (en) * 1997-12-12 1999-10-19 Orion Corporation Method for the prevention and treatment of stunned myocardium

Also Published As

Publication number Publication date
JP2002523494A (en) 2002-07-30
DE19839499A1 (en) 2000-03-02
PL346045A1 (en) 2002-01-14
HUP0103212A3 (en) 2002-06-28
NO20010996D0 (en) 2001-02-27
AU5164199A (en) 2000-03-21
ZA200102565B (en) 2002-06-28
CN1315942A (en) 2001-10-03
BR9913140A (en) 2001-05-08
AR021782A1 (en) 2002-08-07
KR20010072862A (en) 2001-07-31
SK2652001A3 (en) 2001-09-11
WO2000012479A1 (en) 2000-03-09
EP1107954A1 (en) 2001-06-20
ID27863A (en) 2001-04-26
HUP0103212A2 (en) 2002-05-29
CA2342230A1 (en) 2000-03-09
NO20010996L (en) 2001-02-27

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