FR3140540A1 - Mineral and Organic Hybrid Thick Moisturizing Daily Sunscreen - Google Patents

Abstract

Mineral-Organic Hybrid Thick Moisturizing Daily Sunscreen An organo-mineral hybrid sunscreen composition is an oil-in-water emulsion of aqueous and oil phases. The oily phase includes at least one mineral UV filter comprising zinc oxide, a mixture of organic UV filters comprising ethylhexyl methoxycinnamate, ethylhexyl salicylate, octocrylene and homosalate, at least one oil phase solvent, and at least one surfactant and the water phase includes water; at least one solvent miscible in water, and at least one polymer, and at least one filler. The organo-mineral hybrid sunscreen composition has a PI of at least 30 and a critical wavelength of at least 370 nm. Figure for the abstract: none

Description

Mineral and Organic Hybrid Thick Moisturizing Daily Sunscreen FIELD OF DISCLOSURE

The present disclosure relates to organo-mineral hybrid sunscreen compositions and methods of using the organo-mineral hybrid sunscreen compositions to protect keratinous substrates such as skin and hair from UV rays.

CONTEXT

The negative effects of exposure to ultraviolet (“UV”) rays are well known. Prolonged exposure to sunlight causes damage such as sunburn to the skin and dries out hair, making it brittle. When the skin is exposed to UV rays having a wavelength of around 290 nm to around 400 nm, long-term damage can lead to serious conditions such as skin cancer.

UV rays also contribute to aging by causing the formation of free radicals in the skin. Free radicals include, for example, singlet oxygen, hydroxyl radical, superoxide anion, nitric oxide and hydrogen radicals. Free radicals attack DNA, membrane lipids and proteins, generating carbon radicals. These in turn react with oxygen to produce a peroxyl radical which can attack adjacent fatty acids to generate new carbon radicals. This cascade leads to a chain reaction producing lipid peroxidation products. Damage to the cell membrane results in loss of cell permeability, increased intercellular ionic concentration, and decreased ability to excrete or detoxify wastes. The end result is a loss of skin elasticity and the appearance of wrinkles. This process is commonly called photoaging.

Sunscreens can be used to provide protection against UV damage and delay the signs of photoaging. The degree of UV protection offered by an organo-mineral hybrid sunscreen composition is directly related to the amount and type of UV filters it contains. The higher the quantity of UV filters, the higher the degree of UV protection. Consumers prefer that organo-mineral hybrid sunscreen compositions include natural, non-irritating components that appear natural (invisible) when applied. It is known in the art that it is difficult to provide mineral and organic anti-UV sunscreen products having a high sun protection index (IP) which have a long shelf life, are able to retain the benefit of the IP and present a desirable aesthetic when applied by the user.

The inventors of the present disclosure have formulated a thick mineral-organic hybrid moisturizing daily sunscreen that exhibits a high PI and critical wavelength, as well as high emulsion structural stability in the presence of large amounts of agents. UV filtration based on minerals and organics which also provide good aesthetics.

The present disclosure provides an organo-mineral hybrid sunscreen composition that includes mineral and organic UV filter agents, which are considered non-irritating, natural and gentle on the skin, in conjugation with a solvent to oil-based, a surfactant, thickeners, and ceramides and other skin actives, which provide stable sun protection, pleasant sensory and textural properties for the consumer, and structural emulsion stability in the presence of large quantities of mineral UV filters. The organo-mineral hybrid sunscreen composition overcomes problems known in the art where high levels of mineral UV filters have been shown to be unstable. The organo-mineral hybrid sunscreen composition has an in vivo IP 30 and an LOC of at least 370 nm. UV filters are present with a UVA:IP ratio of at least 1:3. The organo-mineral hybrid sunscreen composition has optimized sensory properties that are pleasing to consumers and increased emulsion stability compared to a comparative reference composition as evidenced by 12-week testing and stability testing. at 60°C over a week.

In a representative embodiment, the organo-mineral hybrid sunscreen composition comprises: an oil-in-water emulsion of aqueous and oil phases, comprising:

an oily phase comprising: at least one mineral UV filter comprising zinc oxide; a blend of organic UV filters including ethylhexyl methoxycinnamate, ethylhexyl salicylate, octocrylene and homosalate; at least one oil phase solvent and at least one surfactant;

an aqueous phase comprising: water; at least one solvent miscible in water and at least one polymer; And

at least one charge,

wherein the organo-mineral hybrid sunscreen composition has an IP of at least about 30 and a critical wavelength of at least 370 nm, and wherein the composition is free of UV filters selected from Menthyl anthranilate (meradimate), parabens or a combination thereof.

In some embodiments, the at least one mineral UV filter comprises zinc oxide present in an amount that is at least about 8%; the organic UV filter blend includes approximately 5% ethylhexyl methoxycinnamate, approximately 5% ethylhexyl salicylate, approximately 2% octocrylene, and approximately 10% homosalate, all the quantities being by weight, based on the weight of the composition.

In certain embodiments, the organo-mineral hybrid sunscreen composition optionally comprises at least one skin active.

In some embodiments, the at least one oil phase solvent comprises dimethicone.

In some embodiments, the at least one surfactant is selected from the group consisting of cationic surfactants including a quaternary ammonium salt and a fatty alcohol.

In some embodiments, the at least one water-miscible solvent is selected from the group consisting of alcohols, diols, polyols, and combinations thereof.

In some embodiments, the at least one polymer is selected from the group consisting of celluloses, gums, hydrophilic colloids, and combinations thereof.

In some embodiments, the at least one filler is selected from starches.

In certain particular embodiments, the organo-mineral hybrid sunscreen composition comprises: an oil-in-water emulsion of aqueous and oily phases, comprising:

an oily phase comprising: at least one mineral UV filter comprising zinc oxide present in an amount of at least approximately 8%; a mixture of organic UV filters comprising ethylhexyl methoxycinnamate, present at approximately 5%, ethylhexyl salicylate present at approximately 5%, octocrylene present at approximately 2%, and homosalate present at approximately 10%, all quantities being by weight, based on the weight of the composition; at least one oil phase solvent comprising dimethicone, and at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate;

an aqueous phase comprising: water; a water-miscible solvent comprising glycerin and propanediol; and at least one polymer comprising hydroxyethylcellulose; And

at least one filler comprising aluminum starch octenylsuccinate,

wherein the organo-mineral hybrid sunscreen composition has an IP of at least about 30 and a critical wavelength of at least 370 nm.

In certain particular embodiments, the organo-mineral hybrid sunscreen composition comprises: an oil-in-water emulsion of aqueous and oily phases, comprising:

an oily phase comprising: at least one mineral UV filter comprising zinc oxide present in an amount of at least approximately 8%; a mixture of organic UV filters comprising ethylhexyl methoxycinnamate, present at approximately 5%, ethylhexyl salicylate present at approximately 5%, octocrylene present at approximately 2%, and homosalate present at approximately 0%, all quantities being by weight, based on the weight of the composition; at least one oil phase solvent comprising dimethicone, present in an amount less than or equal to approximately 2%, and at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate present at approximately 4.5%;

an aqueous phase comprising: water; a water-miscible solvent comprising glycerin present at 3% and propanediol present at approximately 3%; and at least one polymer comprising hydroxyethylcellulose present at approximately 0.5%; And

at least one filler comprising aluminum starch octenylsuccinate present at approximately 0.5%,

wherein the organo-mineral hybrid sunscreen composition has an IP of at least about 30 and a critical wavelength of at least 370 nm.

In some embodiments, the weight ratio of the UV filters to the total amount of the oil phase is approximately 80% (based on the total weight of the UV filters and the total weight of the oil phase). In some embodiments, the weight ratio of the oil phase solvent to the total amount of the oil phase is less than or equal to about 5% (based on the total weight of the oil phase solvent and the total weight of the oil phase). oily).

In certain embodiments, the organo-mineral hybrid sunscreen composition further comprises one or a combination of additives selected from the group consisting of solvents, IP enhancers, humectants, waxes, skin care actives, preservatives, pH correctors, chelating agents, cooling agents, fragrances, dyes, pigments and combinations thereof.

In the various embodiments, the organo-mineral hybrid sunscreen composition demonstrates emulsion structural stability wherein the sunscreen composition does not exhibit signs of phase separation, and/or does not become nonhomogeneous. after up to 12 weeks at room temperature in the range of about 5°C to about 45°C, and retains emulsion structural stability, with minimal color change at 60°C for at least one week. In the various embodiments, the organo-mineral hybrid sunscreen composition demonstrates an IP of approximately 30 and an LOC of at least 370 nm.

In certain particular embodiments, the organo-mineral hybrid sunscreen composition comprises: an oil-in-water emulsion of aqueous and oily phases, comprising:

an oily phase comprising: at least one mineral UV filter comprising zinc oxide present in a quantity which is at least approximately 8%; a mixture of organic UV filters comprising ethylhexyl methoxycinnamate, present at approximately 5%, ethylhexyl salicylate present at approximately 5%, octocrylene present at approximately 2%, and homosalate present at approximately 10% , all quantities being by weight, based on the weight of the composition; at least one oil phase solvent comprising dimethicone, present in an amount less than or equal to approximately 2%, and at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate present at approximately 4.5%;

an aqueous phase comprising: water; a water-miscible solvent comprising glycerin present at approximately 3% and propanediol present at approximately 3%; and at least one polymer comprising hydroxyethylcellulose present at approximately 0.5%;

at least one filler comprising aluminum starch octenylsuccinate present at approximately 0.5%; And

an additive or combination of additives selected from the group consisting of solvents, IP enhancers, humectants, waxes, skin care active ingredients, preservatives, pH correctors, chelating agents, cooling agents, perfumes, dyes, pigments and combinations thereof,

wherein the organo-mineral hybrid sunscreen composition has an IP of at least about 30 and a critical wavelength of at least 370 nm, and wherein the organo-mineral hybrid sunscreen composition does not exhibit no signs of phase separation, and/or does not become non-homogeneous after up to 12 weeks at room temperature in the range of about 5°C to about 45°C, and retains emulsion structural stability, with minimal color change at 60°C for at least one week.

In various embodiments, the organo-mineral hybrid sunscreen composition may exclude one or more ingredients selected from the group consisting of menthyl anthranilate, parabens, and combinations thereof.

The present disclosure also relates to methods of protecting the skin from UV rays comprising applying to the skin an effective amount of the organo-mineral hybrid sunscreen composition.

DETAILED DESCRIPTION OF THE DISCLOSURE

When the following terms are used in this specification, they are used as defined below.

The term "active ingredient", as used herein in relation to the percentage of an ingredient or raw material, refers to 100% of the activity of the ingredient or raw material, unless otherwise stated. .

The term "aqueous phase" means water, water-soluble, water-miscible, and water-dispersible ingredients, and represents the sum total of all ingredients in the hybrid sunscreen composition. organo-mineral which are water soluble or water dispersible, and which are combined with water during the preparation of the example emulsion compositions.

The term "oil phase" refers to oil, oil-soluble, oil-miscible, and oil-dispersible ingredients, and represents the sum total of all ingredients in the hybrid sunscreen composition. organo-mineral which are oil soluble or oil dispersible, and which are combined with oil during the preparation of the example emulsion compositions.

The expression “critical wavelength” (λ_vs) refers to the wavelength at which the sunscreen allows 10% of rays to penetrate. The FDA considers sunscreen with a critical wavelength greater than 370 nm to provide excellent UVA protection.

“Cosmetically acceptable” means that the item in question is compatible with a keratinous substrate such as skin and hair. For example, a “cosmetically acceptable vector” means a vector compatible with a keratinous substrate such as skin and hair.

The term "homogeneous" means, with reference to the organo-mineral hybrid sunscreen composition, that it has as a whole a substantially uniform visual appearance, i.e., that it does not visually exhibit separation or accumulation. of fluid.

The term "keratinous tissue" includes, but is not limited to, skin, hair and nails.

The term “mineral UV filter agent” is interchangeable with the terms “mineral UV filter agent”, “inorganic UV filter agent”, “inorganic UV filter agent”, “mineral UV filter” and “inorganic UV filter” . Mineral UV filter agents are compounds that do not include carbon atoms in their chemical structures and are capable of filtering, diffusing or absorbing UV radiation between 280 and 400 nm.

The term "IP enhancer" refers to a material that increases the UV absorption of another material when the two materials are mixed in a composition by refracting UV radiation, thereby increasing the effective path length of the UV radiation through the organo-mineral hybrid sunscreen composition.

The term "emulsion structural stability" refers to the structural stability of the oil-in-water emulsion and means that the organo-mineral hybrid sunscreen composition exhibits an initially good aesthetic appearance, including the absence has a grainy texture, lack of crystal formation, maintenance of a consistent microscopic structure and does not demonstrate visually perceptible phase separation, significant liquid accumulation or droplet formation. Additionally, the organo-mineral hybrid sunscreen composition maintains emulsion structural stability as described above and maintains consistent color, odor, and viscosity during extended storage, including storage for up to 12 weeks, particularly after exposure to ambient temperatures ranging from approximately 25°C to approximately 45°C. For example, an organo-mineral hybrid sunscreen composition is considered to demonstrate emulsion structure stability if the organo-mineral hybrid sunscreen composition does not exhibit signs of phase separation and/or does not does not become non-homogeneous after up to 12 weeks at room temperature in the range of approximately 5°C to approximately 45°C inclusive.

The term "substantially free" or "substantially free" as used herein means that less than about 2% by weight of a specific material is added to a composition, based of the total weight of the organo-mineral hybrid sunscreen compositions. However, the organo-mineral hybrid sunscreen compositions may include less than about 1 wt.%, less than about 0.5 wt.%, less than about 0.1 wt.%, less than about 0 .01% by weight or no quantity of the specified material.

The expression "sun protection index" or "IP" is a value expressed mathematically by the ratio between the irradiation time necessary to reach the erythemogenic threshold with the anti-UV agent and the time necessary to reach the erythemogenic threshold without anti-UV agent. The PI generally provides information about the skin's resistance to ultraviolet B (UVB) radiation from the sun. The IP rating system was developed to guide consumers in the choice of sunscreens. The organo-mineral hybrid sunscreen composition according to the present publication can be formulated to achieve a variety of different PIs. For example, the organo-mineral hybrid sunscreen composition may have an in vivo PI of at least 30, 35, 40, 45, 50 or 55 or more (or in a range between any of these values ). As demonstrated herein, in some embodiments, the organo-mineral hybrid sunscreen composition has a PI of at least 50 or greater, measured as defined by the FDA's 2011 PI testing method and/or on a tested subject.

The term “water-in-oil emulsion” or “W/O emulsion” includes an aqueous phase dispersed in an oil phase, where the oil phase is a continuous phase.

The present disclosure relates to an organo-mineral hybrid sunscreen composition and embodiments thereof that provide a high degree of sun protection, structural emulsion stability as demonstrated by macroscopic and microscopic examination, and sensory texture. optimized and unique, the hybrid organo-mineral sunscreen composition including in the oily phase at least one mineral UV filter and a mixture of organic UV filters, at least one oil-based solvent, at least one surfactant and in the aqueous phase, water, at least one solvent miscible in water, one or more skin active ingredients, a water-soluble polymer, the organo-mineral hybrid solar composition also including at least one filler. The organo-mineral hybrid sunscreen composition is characterized by a solvent oil phase solvent:total oil phase ratio of less than or equal to 5%.

The inventors surprisingly discovered that by reducing the quantity of solvent in the lipid phase compared to a comparative reference composition in which the solvent is usually used to disperse the UV filter and by adding a filler, they were able to increase the IP of the formula and provide a composition with a thick creamy texture that is appreciated by consumers. Various comparative examples demonstrate that the same formula as that of the invention without the filler and/or with more solvents does not reach IP 30 and does not meet the critical wavelength requirements. Furthermore, compared to the comparative reference composition, the inventive composition demonstrates better stability based on macroscopic and microscopic examination of the emulsion under reliable variable conditions.

The inventors have discovered that in the organo-mineral hybrid sunscreen composition with high UV filters (e.g., in the exemplary inventive composition having 22% organic filters and 8% mineral filter) with an amount of solvent in the lipid phase which is less than or equal to 5% by weight of the oil phase, and the inclusion of a filler, the IP of the formula is maintained at an IP 30 or higher with a surprisingly thick creamy texture that provides a rich skin finish appreciated by consumers. Comparative examples demonstrate that higher amounts of oil phase solvent (greater than 5% by weight of oil phase) and filler removal, even with the same amount of UV filters, results in a significant reduction in IP .

The organo-mineral hybrid sunscreen composition demonstrates emulsion structural stability wherein the sunscreen composition does not exhibit signs of phase separation, and/or does not become non-homogenous after up to 12 weeks at room temperature in the range of about 5°C to about 45°C, and retains emulsion structural stability, with minimal color change at 60°C for at least one week. In the various embodiments, the organo-mineral hybrid sunscreen composition demonstrates an IP of approximately 30 and an LOC of at least 370 nm.

In exemplary embodiments, the organo-mineral hybrid sunscreen composition is free or devoid of organic UV filters selected from menthyl anthranilate (meradimate), parabens, or a combination thereof.

UV filters

According to the various embodiments, the organo-mineral hybrid sunscreen composition according to the disclosure includes at least one inorganic/mineral UV filter and a mixture of organic UV filters present in the oily phase of the emulsion.

In particular, the organo-mineral hybrid sunscreen composition includes zinc oxide and a combination of organic UV filters including octinoxate (ethylhexyl methoxycinnamate), occisalate (ethylethyl salicylate), octocrylene and homosalate.

In some particular embodiments, the organo-mineral hybrid sunscreen composition excludes, or is free or devoid of, organic UV filters comprising menthyl anthranilate (meradimate). In some particular embodiments, the organo-mineral hybrid sunscreen composition excludes, or is free or devoid of, organic UV filters selected from oxybenzone and octinoxate organic UV filters.

In various embodiments of the organo-mineral hybrid sunscreen composition, the zinc oxide UV filter is present in an amount of about 8% by weight of the organo-mineral hybrid sunscreen composition, octinoxate (ethylhexyl methoxycinnamate) is present in an amount in the range of about 1% to about 8%, or at about 5%, octisalate (ethylhexyl salicylate) is present in an amount in the range from about 1% to about 7%, or about 5%, octocrylene is present in an amount in the range of about 0.5% to about 5%, or about 2%, and homosalate is present in an amount in the range of about 5% to about 15%, or about 10%, each present by weight based on the total weight of the organo-mineral hybrid sunscreen composition. Thus, an organic UV filter may be present in the organo-mineral hybrid sunscreen composition, alone as described above, or in combination, by weight, based on the total weight of the hybrid sunscreen composition. organo-mineral, of approximately 0.5, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 , 21, 22, 23, 24 to approximately 25% by weight, including increments and ranges between these values.

Oil

According to the various embodiments, the organo-mineral hybrid sunscreen composition includes any or a combination of cosmetic oils. In some embodiments, the oil is generally immiscible in water.

In some embodiments, the oil is a silicone oil. In some particular embodiments, the oil includes dimethicone.

The oil can be chosen from silicones, hydrocarbons, fatty alcohols, glycols and vegetable oils. The oil may include a polar or non-polar oil or a combination thereof. In certain embodiments, the oil can be chosen from hydrocarbon-based oils derived from plants or of vegetable origin, mineral oil, ester oils, fatty alcohols containing 12 to 26 atoms of carbon, fatty acids containing 12 to 26 carbon atoms and vinylpyrrolidone copolymers, and combinations thereof.

The expression “silicone oil” designates an oil comprising at least one silicon atom, and in particular at least one Si-O group. The expression “fluorinated oil” designates an oil comprising at least one fluorine atom. The term “hydrocarbon-based oil” means an oil comprising primarily hydrogen and carbon atoms. The hydrocarbon-based oil may be a hydrocarbon-based animal oil, a hydrocarbon-based vegetable oil, a hydrocarbon-based mineral oil, or a hydrocarbon-based synthetic oil. Additionally, a suitable oil may be a hydrocarbon-based mineral oil, a hydrocarbon-based vegetable oil, or a hydrocarbon-based synthetic oil.

Silicone oils

The organo-mineral hybrid sunscreen composition may include one or more silicone oils. Non-limiting examples of silicone oils include dimethicone, cyclomethicone, polysilicone-11, phenyl trimethicone, trimethylsilylamodimethicone and steaoxytrimethylsilane. In some cases, the organo-mineral hybrid sunscreen composition includes dimethicone and, optionally, additional oils, including additional silicone oils. Generally, the one or more silicone oils are non-volatile silicone oil. In some embodiments, the silicone oil is polydimethylsiloxanes (PDMS), polydimethylsiloxanes comprising alkyl or alkoxy groups that are pendant and/or at the end of the silicone chain, which groups each contain from 2 to 24 carbon atoms, or phenyl silicones, such as phenyl trimethicones, phenyl dimethicones, phenyl(trimethylsiloxy)diphenylsiloxanes, diphenyl dimethicones, diphenyl(methyldiphenyl)trisiloxanes or (2-phenylethyl)trimethylsiloxysilicates.

Other examples of silicone oils which may be mentioned include linear or cyclic volatile silicone oils, particularly those having a viscosity of 8 centistokes (8 x 106 m2/s) and particularly containing 2 to 7 atoms of silicon, these silicones optionally comprising alkyl or alkoxy groups containing from 1 to 10 carbon atoms. As volatile silicone oils which can be used in the invention, mention may be made in particular of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, heptamethylhexyltrisiloxane, heptamethyloctyltrisiloxane, hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane and dodecamethylpentasiloxane, and mixtures thereof.

Fluorinated oils

The organo-mineral hybrid sunscreen composition may include one or more fluorinated oils. For example, the one or more fluorinated oils may be selected from the group consisting of perfluoromethylcyclopentane, perfluoro-1,3-dimethylcyclohexane, dodecafluoropentane, tetradecafluorohexane, bromoperfluorooctyl, nonafluoromethoxybutane, nonafluoroethoxyisobutane, and 4-trifluoromethylperfluoromorpholine. Volatile fluorinated oils, such as nonafluoromethoxybutane, decafluoropentane, tetradecafluorohexane, and dodecafluoropentane, can also be used.

Hydrocarbon-based oils

The organo-mineral hybrid sunscreen composition may include one or more hydrocarbon-based oils. For example, the hydrocarbon-based oil may be a saturated hydrocarbon, an unsaturated hydrocarbon, lipids, triglycerides, a natural oil and/or a synthetic oil. In some embodiments, the organo-mineral hybrid sunscreen composition may include a synthetic oil selected from the group consisting of hydrogenated polyisobutene and hydrogenated polydecene. A hydrocarbon-based oil may be a non-volatile hydrocarbon-based oil, such as:

(i) hydrocarbon-based oils of plant origin, such as glyceride triesters, which are generally triesters of fatty acids and glycerol, the fatty acids of which may have chain lengths varying from C4 to C24 , these chains can be saturated or unsaturated and linear or branched; these oils are in particular wheat germ oil, sunflower oil, grape seed oil, sesame oil, corn oil, apricot oil, castor oil, shea oil, avocado oil, olive oil, soybean oil, sweet almond oil, palm oil, rapeseed oil, cottonseed oil, hazelnut oil, macadamia oil, jojoba oil, alfalfa oil, poppy seed oil, pumpkin seed oil, pumpkin seed oil squash, blackcurrant oil, evening primrose oil, millet oil, barley oil, quinoa oil, rye oil, safflower oil, bancoul, passionflower oil and rosehip oil.

(ii) synthetic ethers containing 10 to 40 carbon atoms;

(iii) linear or branched hydrocarbons of mineral or synthetic origin, such as petroleum jelly, polydecenes, hydrogenated polyisobutene such as Parleam® and squalane 40;

(iv) synthetic esters, for example oils of formula RCOOR' in which R represents a linear or branched fatty acid residue containing from 1 to 40 carbon atoms and R' represents a hydrocarbon-based chain which is in branched particular, containing from 1 to 40 carbon atoms provided that R + R' is equal to ÿ 10, for example, Purcellin oil (cetearyl octanoate), isopropyl myristate, isopropyl palmitate, C12-C15 alkyl benzoate, such as the product sold under the trade name Finsolv TN® or Witconol TN® by Witco or Tegosoft TN® by Evonik Goldschmidt, 2-ethylphenyl benzoate, such as the commercial product sold under the name X-Tend 226 by ISP, isopropyl lanolate, hexyl laurate, diisopropyl adipate, isononyl isononanoate, oleyl erucate, 2-ethylhexyl palmitate, isostearyl isostearate, diisopropyl sebacate, such as the product sold under the name “Dub Dis” by Stéarinerie Dubois; octanoates, decanoates or ricinoleates of alcohols or polyalcohols, such as propylene glycol dioctanoate; hydroxylated esters, such as isostearyl lactate or diisostearyl malate; and pentaerythritol esters; citrates or tartrates, such as di(linear C12-C13 alkyl) tartrates, such as those sold under the name Cosmacol ETI® by Enichem Augusta Industriale, as well as di(linear C14-C15 alkyl) tartrates , such as those sold under the name Cosmacol ETL® by the same company; or acetates;

(v) fatty alcohols which are liquid at room temperature, containing a branched and/or unsaturated carbon chain containing 12 to 26 carbon atoms, for example octyldodecanol, isostearyl alcohol, oleyl alcohol, 2- hexyldecanol, 2-butyloctanol and 2-undecylpentadecanol;

(vi) higher fatty acids, such as oleic acid, linoleic acid or linolenic acid;

(vii) carbonates, such as dicaprylyl carbonate, such as the product sold under the name Cetiol CC(TM) by Cognis;

(viii) fatty amides, such as isopropyl N-lauroyl sarcosinate, such as the product sold under the trade name Eldew SL 205(TM) from Ajinomoto; And

(ix) essential oils selected from the group consisting of sunflower oil, sesame oil, peppermint oil, macadamia nut oil, tea tree oil, evening primrose oil, sage oil, rosemary oil, coriander oil, thyme oil, chili berry oil, rose oil, anise oil, balsamic oil, bergamot oil, rosewood oil, cedar oil, chamomile oil, sage oil, sage oil clary, clove oil, cypress oil, eucalyptus oil, fennel oil, sea fennel oil, frankincense oil, geranium oil, ginger oil, grapefruit oil, jasmine oil, juniper oil, oil lavender, lemon oil, lemongrass oil, lime oil, tangerine oil, marjoram oil, myrrh oil, neroli oil, orange oil, patchouli oil, pepper oil, pepper oil black, petitgrain oil, pine oil, rose otto oil, rosemary oil, sandalwood oil, spearmint oil, nard oil, vetiver oil, Canadian wintergreen oil and ylang ylang.

The hydrocarbon-based oils may be triesters of glycerides and in particular triglycerides of caprylic/capric acid, synthetic esters and in particular isononyl isonanoate, oleyl erucate, benzoate of C12-C15 alkyl, 2-ethylphenyl benzoate and fatty alcohols, such as octyldodecanol. As volatile oils based on hydrocarbons, mention may be made of oils based on hydrocarbons containing 8 to 16 carbon atoms and in particular branched C8-C16 alkanes, such as C8-C16 isoalkanes. of petroleum origin (also known as isoparaffins), such as isododecane (also known as 2,2,4,4,6-pentamethylheptane), isodecane or isohexadecane, oils sold under the trade names Isopar or Permethyl, branched C8-C16 esters and isohexyl neopentanoate.

In some embodiments, the organo-mineral hybrid sunscreen composition may include one or more oils such as those described above, and oils that may be selected from a branched or linear liquid alkane with a length carbon chain from C11 to C20. In various embodiments, the liquid alkanes may be selected from those having a carbon chain length of C11 to C20. The liquid alkanes may be selected from those having a carbon chain length of C11 to C20, or C15 to C19, or one of C11, C12, C13, C14, C15, C16, C17, C18 and C19. In some embodiments, suitable liquid alkanes that may be used according to the disclosure include hydrocarbon-based oils containing 8 to 16 carbon atoms, and particularly branched C8-C16 alkanes such as C8 isoalkanes. -C16.

In some embodiments, the organo-mineral hybrid sunscreen composition may comprise one or more oils selected from polar emollients selected from esters, triglycerides, ethers, carbonates, alcohols, oils, butters, fatty acids and combinations thereof. In various embodiments, the polar emollients may be selected from those having a molecular weight of 400 g/mol or less. More generally, the polar emollient may have a molecular weight in the range of about 50 g/mol% to about 350 g/mol.

In some embodiments, the organo-mineral hybrid sunscreen composition may include polar emollients that include those derived from C12-C50 fatty acids, preferably C16-C22 saturated fatty acids, and monohydric alcohols. . In certain embodiments, these esters can be chosen from isopropyl myristate, methyl palmitate, isopropyl laurate, isopropyl palmitate, ethylhexyl palmitate, ethylhexyl laurate, oleate ethylhexyl, ethylhexyl isononanoate, myristyl myristate, 2-ethylhexyl caprate/caprylate (or octyl caprate/caprylate), 2-ethylhexyl palmitate, isostearyl neopentanoate, isononanoate of isononyl, hexyl laurate, esters of lactic acid and fatty alcohols comprising 12 or 13 carbon atoms, dicaprylyl carbonate and mixtures thereof.

The one or more oils, alone or combined as an oil blend, may be present in the organo-mineral hybrid sunscreen composition from about 0.0001% to about 10% or from about 0.001 % to about 0.010%, or from about 0.01% to about 0.1%, or from about 0.1% to about 10%, or from about 0.5% to about 20%, or about 1% to about 10%, or about 5% to about 10%, or about 1% to about 3%, or about 1% to about 2%, or any combination, sub-combination, range or appropriate subrange of these weight values, based on the weight of the organo-mineral hybrid sunscreen composition. A person of ordinary skill in the art will, however, appreciate that other ranges are within the scope of the invention. In some embodiments, the organo-mineral hybrid sunscreen composition includes multiple oils, each oil being present in an amount as set forth above, wherein each different oil (such as, e.g., vegetable oils and extracts with oils) may be present in any of the ranges selected from the ranges stated above.

Thus, each of the at least one oil or combination of oils is present by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, of approximately 0.0001, 0.001, 0.01, 0 .1, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2, 3, 4, 5 , 6, 7, 8, 9, to approximately 10%, including increments and ranges between these values.

Surfactant

In various embodiments, the organo-mineral hybrid sunscreen composition comprises at least one surfactant.

In some embodiments, the surfactants may be selected from the group consisting of cationic surfactants including quaternary ammonium compounds, in some embodiments including a quaternary ammonium salt and a fatty alcohol and combinations thereof.

In some particular embodiments, the organo-mineral hybrid sunscreen composition comprises at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate.

Non-limiting examples of cationic surfactants include behentrimonium methosulfate, behentrimonium chloride, cetrimonium chloride, stearimonium chloride, behenamidopropyltrimonium methosulfate, stearamidopropyltrimonium chloride, arachidtrimonium chloride, distearyldimonium chloride, dicetyldimonium chloride, tricetylmonium chloride, oleamidopropyl dimethylamine, linoleamidopropyl dimethylamine, isostearamidopropyl dimethylamine, oleyl hydroxyethyl imidazoline, stearamidopropyldimethylamine, behenamidopropyldimethylamine, behenamidopropyldiethylamine, behenamidoethyldiethylamine, behenamido thyldimethylamine, arachidamidopropyldimethylamine, arachidamido-propyidiethylamine, arachimidoethyldiethylamine, arachidamidoethydimethylamine, brassicamidopropyldimethylamine, lauramidopropyl dimethylamine, myristamidopropyl dimethylamine, dilinoleamidopropyl dimethylamine, palmitamidopropyl dimethylamine and mixtures thereof.

In some embodiments, cetearyl alcohol (and) behentrimonium methosulfate is present from about 0.1% to about 10%, or from about 0.8% to about 6%, or about 4% about 5%, or about 4.5%, all amounts being by weight based on the total weight of the organo-mineral hybrid sunscreen composition.

Each of the at least one surfactant is present in the organo-mineral hybrid sunscreen composition at a concentration of from about 0.1% to about 10%, or from about 0.2% to 10%, or approximately 1% to 5% by weight, all weights being based on the total weight of the organo-mineral hybrid sunscreen composition. Thus, in various embodiments, each surfactant or combination of surfactants is present in the organo-mineral hybrid sunscreen composition in a weight percent amount ranging from 0.1, 0.2, 0, 3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, to approximately 10% by weight, including increments between these values.

Polymer

In various embodiments, the organo-mineral hybrid sunscreen composition comprises at least one polymer. In some embodiments, the at least one polymer is selected from the group consisting of celluloses, gums, hydrophilic colloids, and combinations thereof.

The polymers may be selected from the group consisting of nonionic, anionic, cationic and amphoteric polymers, such as polysaccharides which include chitosan, chitin, starches, alginates, celluloses, galactomannans such as guar gums and their derivatives, including hydroxypropyl guar, cationic guar derivatives, gums of microbial origin, including xanthan gum, scleroglucan gum, mucopolysaccharides, chondroitin sulfates, and mixtures thereof, and gums derived from plant exudates, including locust bean gums, gum arabic, ghatti gum, karaya gum, tragacanth gum, carrageenan gum, agar agar gum and carob gum, cellulose-based polymers, including methylcellulose, hydroxyalkylcellulose, ethylhydroxyethylcelluloses, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, cationic cellulose ether derivatives, quaternized cellulose derivatives, nitrocellulose, hemicellulose and hemicellulose derivatives, mannans, xylans, lignins, arabans, galacturonans , alginate-based compounds, glucuronoxylans, arabinoxylans, xyloglucans, glucomannans, fructans such as inulin, pectic acids and pectins, arabinogalactans, agars, glycosaminoglycans, gelatin, gellan , crosslinked homopolymers of acrylic acid and combinations thereof.

In some particular embodiments, the organo-mineral hybrid sunscreen composition comprises at least one polymer comprising hydroxyethylcellulose.

The at least one polymer is present in the organo-mineral hybrid sunscreen composition according to the disclosure from about 0.01% to about 10% by weight, or from about 0.05% to about 5% by weight, or about 0.1% to about 2%, or about 0.5%, or any suitable combination, sub-combination, range or sub-range of these values by weight, based on the weight of the composition of organo-mineral hybrid sunscreen.

Thus, a polymer or combination of polymers may be present, by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, of approximately 0.01, 0.02, 0, 03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 2, 3, 4, 5, 6, 7, 8, 9 to approximately 10% by weight, including increments and ranges between these values.

Charge

According to various embodiments, the organo-mineral hybrid sunscreen composition includes one or more fillers. The fillers may be of mineral or organic origin, natural or synthetic in nature and, in some examples, are selected from oil absorption or optical effect fillers. Oil-absorbing fillers can impart a matte effect and non-greasy feel to the skin. Optical effect fillers may impart a blurring/hazing effect to the skin, give the skin a more even appearance, reduce the appearance of skin blemishes or discolorations, or reduce the visibility of pores.

In some embodiments according to the disclosure, a filler may include one or more starches, salts and combinations thereof.

In some particular embodiments according to the disclosure, a filler may include an aluminum starch octenyl succinate.

Examples of oil absorption fillers include: aluminum starch octenyl succinate, mica, zea may (corn) starch, magnesium oxide, nylon-12, nylon-66, cellulose, polyethylene, talc , talc (and) methicone, talc (and) dimethicone, perlite, sodium silicate, pumice, PTFE, polyacryloyldimethyl ammonium taurate, polymethyl methacrylate, oryza sativa (rice) starch, modified potato starch, alumina , sodium-calcium borosilicate, magnesium carbonate, hydrated silica, cross-linked dimethicone/vinyl dimethicone polymer, sodium carboxymethyl starch. According to a preferred embodiment, the oil absorption filler comprises spherical microparticles of porous silica having an average particle size of 0.5 to 20 μm whose INCI name is the silica sold by the company JCG Catalysts and Chemicals under the name Spheron L-1500. According to another preferred embodiment, the oil absorption filler comprises hydrophobic airgel particles whose INCI name is silica silylate sold by Dow Corning under the name VM-2270 Aerogel Fine Particles.

Examples of fillers with optical effects include: bismuth oxychloride, silica silylate, boron nitride, iron oxide, calcium carbonate, calcium sulfate (and) iron oxides, sodium potassium aluminum silicate .

Examples of fillers that exhibit both oil absorption and optical effects include: silica, silica (and) methicone, silica (and) dimethicone, polysilicone-22, polysilicone-8, polysilicone-11, cross-linked polymer methyl methacrylate, polymethylsilsesquioxane, cross-linked methylsilanol/silicate polymer, cross-linked vinyl dimethicone/dimethicone silsesquioxane polymer, cross-linked diphenyl dimethicone/vinyl diphenyl dimethicone silsesquioxane polymer, and styrene/acrylates copolymer.

The filler may be present in the organo-mineral hybrid sunscreen composition according to the invention, at a concentration of either about 0.01% to 10%, or about 0.01% to 5%, or about 0.1% to 1%, or about 0.2% to 0.8%, or about 0.3% to 0.4%, or about 0.5%, or any combination , appropriate subcombination, range or subrange of these values by weight, based on the weight of the organo-mineral hybrid sunscreen composition. A person of ordinary skill in the art will, however, appreciate that other ranges are within the scope of the invention. In some embodiments, the organo-mineral hybrid sunscreen composition includes multiple fillers, each filler being present in an amount defined above, wherein each different filler may be present in one of the selected ones of the ranges stated above.

Thus, each filler or combination of fillers may be present by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, of approximately 0.01, 0.02, 0.03, 0, 04, 0.05, 0.06, 0.07, 0.08, 0.09, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, approximately 10% by weight , including the increments and ranges between these values.

Water

According to the various embodiments, the organo-mineral hybrid sunscreen composition includes water.

In various embodiments, the organo-mineral hybrid sunscreen composition comprises from about 40% to about 70% water, and in some embodiments from about 45% to about 50% water, including including increments and all ranges and subranges between these values, by weight, based on the total weight of the organo-mineral hybrid sunscreen composition. A person of ordinary skill in the art will, however, appreciate that other ranges are within the scope of the invention. Thus, water is present, by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, approximately 40, 45, 50, 55, 60, 65, 66, 67, 68 , 69 to approximately 70% by weight, including increments and all ranges and subranges between these values.

The water used in the organo-mineral hybrid sunscreen composition may be sterile demineralized water and/or floral water such as rose water, cornflower water, chamomile water or water lime, and/or natural thermal or mineral water such as, for example: Vittel water, water from the Vichy basin, Uriage water, La Roche Posay water, water from La Bourboule, water from Enghien-les-Bains, water from Saint Gervais-les-Bains, water from Néris-les-Bains, water from Allevar-les-Bains, water from Digne, water from Maizières, water from Neyrac-les-Bains, water from Lons-le-Saunier, water from Eaux Bonnes, water from Rochefort, water from Saint Christau, water from Fumades, water from Tercis-les-Bains or water from Avène. The aqueous phase can also include reconstituted thermal water, that is to say water comprising trace elements such as zinc, copper, magnesium, etc., reconstituting the characteristics of thermal water.

Water-soluble solvents

According to various embodiments, the organo-mineral hybrid sunscreen composition comprises at least one water-soluble solvent. The term "water-soluble solvent" is interchangeable with the term "water-miscible solvent" and means a compound that is liquid at 25°C and atmospheric pressure (760 mmHg), and has a solubility of 'at least 50% in the water under these conditions. In some cases, the water-soluble solvent has a solubility of at least 60%, 70%, 80% or 90% in water under these conditions. Non-limiting examples of water-soluble solvents include, for example, glycerin, alcohols (e.g., C1-C30, C1-C15, C1-C10 or C1-C4 alcohols), organic solvents, polyols , glycols or combinations thereof.

In some embodiments, a water-soluble solvent is selected from the group consisting of lower alcohols, diols, polyols, and combinations thereof. In some embodiments, the water-soluble solvent may be propylene glycol, butylene glycol, glycerin, or a combination thereof.

In some particular embodiments according to the disclosure, the water-soluble solvent is selected from the group consisting of glycerin, propanediol and a combination thereof.

As examples of organic solvents, non-limiting mention may be made of monoalcohols and polyols such as ethyl alcohol, isopropyl alcohol, propyl alcohol, benzyl alcohol and phenylethyl alcohol, or glycols or glycol ethers such as, for example, monomethyl, monoethyl and monobutyl ethers of ethylene glycol, propylene glycol or ethers thereof such as, for example, monomethyl ether of propylene glycol, butylene glycol, hexylene glycol, dipropylene glycol as well as diethylene alkyl ethers glycol, for example, monoethyl ether or diethylene glycol monobutyl ether. Other suitable examples of organic solvents are ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, propanediol and glycerin. can be volatile or non-volatile compounds.

Other non-limiting examples of water-soluble solvents include alkanols (polyhydric alcohols such as glycols and polyols) such as glycerin, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, diethylene glycol, butylene glycol , hexylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 1,3-butanediol, 2,3-butanediol, 1,4-butanediol, 3-methyl-1,3-butanediol, 1,5-pentanediol, tetraethylene glycol, 1,6-hexanediol, 2-methyl-2,4-pentanediol, polyethylene glycol, 1,2,4-butanetriol, 1,2,6-hexanetriol, 2-butene-1,4-diol, 2- ethyl-1,3-hexanediol, 2-methyl-2,4-pentanediol, (caprylyl glycol), 1,2-hexanediol, 1,2-pentanediol and 4-methyl-1,2-pentanediol; alkyl alcohols having 1 to 4 carbon atoms such as ethanol, methanol, butanol, propanol and isopropanol; glycol ethers such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol acetate monomethyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, mono-n -propyl ether of diethylene glycol, mono-iso-propyl ether of ethylene glycol, mono-iso-propyl ether of diethylene glycol, mono-n-butyl ether of ethylene glycol, mono-t-butyl ether of ethylene glycol, mono-t-butyl diethylene glycol ether, 1-methyl-1-methoxybutanol, monomethyl propylene glycol ether, monoethyl propylene glycol ether, mono-t-butyl propylene glycol ether, mono-n-propyl ether propylene glycol, mono-iso-propyl ether of propylene glycol, monomethyl ether of dipropylene glycol, monoethyl ether of dipropylene glycol, mono-n-propyl ether of dipropylene glycol and mono-iso-propyl ether of dipropylene glycol; 2-pyrrolidone, N-methyl-2-pyrrolidone, 1,3-dimethyl-2-imidazolidinone, formamide, acetamide, dimethyl sulfoxide, sorbita, sorbitan, acetin, diacetin, triacetin , sulfolane, or combinations thereof.

According to the various embodiments, the amount of the at least one water-soluble solvent, if applicable, is from about 1% to about 20%, or from about 1% to about 10%, or from about 2% to about 8%, or about 3%, or any suitable combination, sub-combination, range or sub-range of these values by weight, based on the weight of the organo-mineral hybrid sunscreen composition . A person of ordinary skill in the art will, however, appreciate that other ranges are within the scope of the invention. In some embodiments, the organo-mineral hybrid sunscreen composition comprises multiple water-soluble solvents, each water-soluble solvent being present in an amount defined above, wherein each water-soluble solvent Different water may be present in any of the ranges selected from the ranges stated above.

Thus, each water-soluble solvent or combination of solvents is present by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, of approximately 1, 2, 3 , 4, 5, 6, 7, 8, 9, 10, 11, 12, 13,14,15, 16, 17, 18, 19 to approximately 20% by weight, including increments and ranges between these values.

Other ingredients

According to various embodiments, the organo-mineral hybrid sunscreen composition according to the disclosure includes one or more ingredients.

IP reinforcers

In some embodiments, the organo-mineral hybrid sunscreen composition according to the disclosure may comprise one or a combination of IP enhancers. In some embodiments, the organo-mineral hybrid sunscreen composition according to the disclosure excludes IP enhancers.

In certain embodiments, the IP enhancer is selected from butyloctyl salicylate, ethylhexyl methoxycrylene, styrene/acrylates copolymer (such as the product sold under the trade name SUNSPHERES TM), ethylenediamine copolymer /stearyl dimer dilinoleate, dimethicone and acrylates/dimethicone copolymer, silicone polymer comprising dimethicone (and) dimethicone/vinyl dimethicone copolymer, Solastay UVA enhancer, and combinations thereof . In some particular embodiments, the IP enhancer comprises butyloctyl salicylate.

The IP enhancer or combination of IP enhancers, if applicable, may be at a concentration of about 0.01% to 25%, in some embodiments about 0.1% to 13%, and in some embodiments about 0.5% to 10%, and in some embodiments about 1% to 5%, or about 3% by weight, all weights being based on weight total of the organo-mineral hybrid sunscreen composition. Thus, in various embodiments, an IP enhancer, if any, may be present in a composition in a weight percent amount of 0.01, 0.02, 0.03, 0.04, 0, 05, 0.06, 0.07, 0.08, 0.09, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, 10.0, 11.0, 12.0, 13.0, 14.0, 15.0, 16.0, 17.0, 18.0, 19.0, 20.0, 21, 0, 22.0, 23.0, 24.0 to 25.0 weight percent, including increments between these values.

Cosmetic waxes

According to the disclosure, one or more waxes may optionally be present in the organo-mineral hybrid sunscreen composition, the wax being selected from natural and synthetic waxes. Natural waxes may include animal tallow, berry wax, beeswax, grapefruit wax, orange peel wax, palm wax, rice bran wax, sumac, sunflower wax, soy wax, polyhydroxystearic acid and combinations thereof.

In some embodiments, where applicable, a wax may be selected from rice bran wax (rice bran wax), candelilla wax, sunflower seed wax, carnauba wax, polyhydroxystearic acid and combinations thereof. . In a particular embodiment, the organo-mineral hybrid sunscreen composition comprises rice bran wax.

According to the various embodiments, the wax or combination of waxes, if applicable, is present in the organo-mineral hybrid sunscreen composition at a concentration, by weight, of about 0.1% to about 10%, or from about 0.2% to about 4%, or from about 0.5% to about 3%, or from about 1% to about 2%, or any combination, sub-combination, range or sub-ranges of these values by weight, based on the weight of the organo-mineral hybrid sunscreen composition.

In some embodiments, the organo-mineral hybrid sunscreen composition includes multiple waxes, each of which is present in the organo-mineral hybrid sunscreen composition at a concentration, by weight, based on the total weight of the composition of organo-mineral hybrid sunscreen, in the range of about 0.1% to about 10%, or any combination, sub-combination, range or sub-range of these values by weight, based on the weight of the organo-mineral hybrid sunscreen composition.

Thus, where applicable, the wax is present by weight, based on the total weight of the organo-mineral hybrid sunscreen composition of approximately 0.10, 0.20, 0.30, 0.40, 0 .50, 0.60, 0.70, 0.80, 0.90, 1.0, 2, 3, 4, 5, 6, 7, 8, 9, to approximately 10% by weight, including increments and ranges between these values.

Powders

According to some embodiments, the organo-mineral hybrid sunscreen composition according to the disclosure may optionally comprise one or a combination of powders including sensory experience modification powders. In certain particular embodiments, the powders can be selected from boron nitride, perlite and aluminum starch octenylsuccinate.

The powder or combination of powders, if applicable, may be at a concentration of about 0.05% to 15%, in some embodiments about 0.1% to 10%, and in some embodiments from about 1% to 5% by weight, all weights being based on the total weight of the organo-mineral hybrid sunscreen composition. Thus, in various embodiments, a powder, if any, may be present in a composition in a weight percent amount of 0.05, 0.06, 0.07, 0.08, 0.09, 1 .0, 2.0, 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, 10.0, 11.0, 12.0, 13.0 , 14.0 to 15.0% by weight, including increments between these values.

Actives/other additives

The organo-mineral hybrid sunscreen compositions may also comprise one or a combination of optional active ingredients or additives used in the cosmetic field which does not affect the properties of the organo-mineral hybrid sunscreen compositions according to the invention, such as fragrances, colorants, pearlescent agents, silica, preservatives, proteins, protein hydrolysates, ceramides, antioxidants, vitamins (e.g. vitamin C, vitamin B, vitamin E, vitamin A, vitamin D and derivatives, provitamins and vitamers of these, including, but not limited to, ascorbic acid, panthenol, tocopherol, tocotrienol, retinol, calciferol), silicones, odor absorbers and coloring materials; antimicrobial components, including but not limited to phenoxyethanol, chlorphenesin, capryloyl glycol and sodium salicylate; essential oils selected from the group consisting of sunflower oil, sesame oil, peppermint oil, walnut oil macadamia, tea tree oil, evening primrose oil, sage oil, rosemary oil, coriander oil, thyme oil, chili oil, rose oil, anise oil, balsamic oil, bergamot oil, rosewood oil, cedarwood oil, chamomile oil, clary sage oil, clove oil, cypress oil, cypress oil, eucalyptus oil, fennel oil, sea fennel oil, sea fennel oil frankincense, geranium oil, ginger oil, grapefruit oil, jasmine oil, juniper oil, lavender oil, lemon oil, lemongrass oil, lime oil, mandarin oil, marjoram oil, myrrh oil , neroli oil, orange oil, patchouli oil, pepper oil, black pepper oil, petitgrain oil, pine oil, rose otto oil, rosemary oil, sandalwood oil, spearmint oil , spikenard oil, vetiver oil, Canadian wintergreen oil and ylang ylang; fruit extracts, for example, Pyrus Malus (apple) fruit extract and Aloe Barbadensis leaf juice powder; citric acid, sodium chloride; pH neutralizing or correcting agents (e.g., triethylamine (TEA) and sodium hydroxide), and combinations thereof. Ceramides may include a ceramide complex, a mixture of ceramides that includes ceramide NP, ceramide AP, and ceramide EOP (e.g., SK-INFLUX(TM) from Evonik).

Although the optional active ingredients/additives are given as examples, it will be appreciated that other optional components compatible with cosmetic applications known in the art may be used.

In some embodiments, the organo-mineral hybrid sunscreen composition may include one or a combination of trisodium ethylenediamine disuccinate, hydroxyacetophenone, sodium hyaluronate, hydrolyzed hyaluronic acid, ceramides, phenoxyethanol, niacinamide, diethylhexyl syringylidenemalonate, citric acid , EDTA, propyl paraben, methyl paraben, panthenol, tocopherol, and combinations thereof.

In some particular embodiments, the organo-mineral hybrid sunscreen composition includes trisodium ethylenediamine disuccinate, hydroxyacetophenone, sodium hyaluronate, hydrolyzed hyaluronic acid, ceramides, niacinamide, and combinations of these.

Depending on the various embodiments, the amount of each or a combination of optional active ingredients/additives, if any, in the organo-mineral hybrid sunscreen composition may be present in a range from about 0.001% to about 20%, by weight, from about 0.005% to about 0.01%, from about 0.01% to about 0.1%, or from about 0.15% to about 5%, or from about 0.40% to about 4%, or from about 0.5% to about 2.5% by weight, or from about 1% to about 2%, or any combination, sub-combination, range or sub- range of these values by weight, based on the total weight of the organo-mineral hybrid sunscreen composition. And in some embodiments, a combination of actives present in the organo-mineral hybrid sunscreen composition may be present in a range from about 0.001% to about 20%.

Thus, any or a combination of optional active ingredients/additives, if any, may be present, by weight, based on the total weight of the organo-mineral hybrid sunscreen composition, approximately 0.001, 0.002, 0.003, 0.004, 0.005, 0.006, 0.007, 0.008, 0.009, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08 , 0.09, 0.10, 0.20, 0.30, 0.40, 0.50, 0.60, 0.70, 0.80, 0.90, 1.0, 2, 3, 4 , 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 to approximately 20% by weight, including increments and ranges between these values.

The present disclosure also relates to methods of protecting the skin against UV radiation comprising applying to the skin an effective amount of the organo-mineral hybrid sunscreen composition according to claim 1.

Examples

The following examples are provided for illustrative purposes only and are not intended to be limiting.

EXAMPLE 1 : Raw materials

The selected raw materials as used in the organo-mineral hybrid sunscreen composition are identified in the table below.

[TABLE 1] Representative raw materials

Raw material Active percentage ZnO (Z-COTE HP1 (TM)) ~98% active ZnO Octocrylene ~100% Homosalate ~100% Octinoxate ~100% Octisalate ~100% Aluminum starch octenyl succinate ~100% Dimethicone ~100%

EXAMPLE 2: Inventive, basic and comparative compositions

An organo-mineral hybrid sunscreen composition according to the disclosure was prepared and demonstrated the physical and chemical properties as described below. The inventive composition has been evaluated by an FDA method of in vivo IP characterization, achieving a value of 30 or greater, and demonstrates stability and sensory properties, as described herein. The compositions are each described in Tables 2-5 below.

[TABLE 2] Example of inventive composition

Ingredient Phase INVENTIVE ORGANIC UV FILTERS (ETHYLHEXYL METHOXYCINNAMATE/OCTINOXATE (~5%), ETHYLHEXYL SALICYLATE (~5%), OCTOCRYLENE (~2%), HOMOSALATE (~10%) OILER ~22 OILY PHASE SOLVENT (DIMETHICONE) OILER ~2 MINERAL UV FILTER (ZINC OXIDE*) OILER ~8.21 SURFACTANT (CETEARYL ALCOHOL (and) BEHENTRIMONIUM METHOSULFATE) OILER ~4.5 OTHER ADDITIVES/PRESERVATIVES (THYLENEDIAMINE TRISODIC DISUCCINATE, HYDROXYACETOPHENONE, PHENOXYETHANOL) AQUEOUS ~1 SKIN ACTIVE INGREDIENTS (SODIUM HYALURONATE, CERAMIDE BLEND, NIACINAMIDE) AQUEOUS ~5 FILLER (ALUMINUM STARCH OCTENYSUCCINATE) ~0.5 POLYMER (HYDROXYETHYLCELLULOSE) AQUEOUS ~0.5 AQUEOUS PHASE SOLVENT (GLYCERIN, PROPANEDIOL) AQUEOUS ~6 WATER AQUEOUS ~50.5 (QS) UV filter: oily phase weight ratio =~0.82 Oil phase solvent:oil phase weight ratio (</=5 %) = ~0.05

*ZnO RM; final assets are ~8%

[TABLE 3] Comparative composition Ingredient Phase COMPARATIVE ORGANIC UV FILTERS (ETHYLHEXYL METHOXYCINNAMATE (~5%), MENTHYL ANTHRANILATE (MERADIMATE) (~5%), OCTOCRYLENE (~2%), HOMOSALATE (~10%)) OILER ~22 OILY PHASE SOLVENT (DIMETHICONE) OILER ~1 MINERAL UV FILTER (ZINC OXIDE*) OILER ~6.46 SURFACTANT (CETEARYL ALCOHOL (and) BEHENTRIMONIUM METHOSULFATE) OILER ~4 OTHER ADDITIVES/PRESERVATIVES (DISODIUM EDTA, METHYL PARABEN, PROPYL PARABEN) AQUEOUS ~0.5 SKIN ACTIVE INGREDIENTS (HYDROLYZED HYALURONIC ACID, CERAMIDE BLEND, NIACINAMIDE) AQUEOUS ~4.8 FILLER (ALUMINUM STARCH OCTENYSUCCINATE) ~0.5 POLYMER (HYDROXYETHYLCELLULOSE) AQUEOUS ~0.5 AQUEOUS PHASE SOLVENT (GLYCERIN) AQUEOUS ~3 WATER AQUEOUS ~58 (QS) UV filter: oily phase weight ratio =~0.85 Oil phase solvent:oil phase weight ratio (</=5 %) = ~0.03

*ZnO RM; the final Zn active is ~8%

[TABLE 4] Basic composition (for various compositions) Ingredient INVENTIVE ORGANIC UV FILTERS (ETHYLHEXYL METHOXYCINNAMATE/OCTINOXATE, ETHYLHEXYL SALICYLATE, OCTOCRYLENE, HOMOSALATE) Miscellaneous OILY PHASE SOLVENT (DIMETHICONE) Miscellaneous MINERAL UV FILTER (ZINC OXIDE) Miscellaneous SURFACTANT (CETEARYL ALCOHOL (and) BEHENTRIMONIUM METHOSULFATE) ~4.5 OTHER ADDITIVES/PRESERVATIVES (THYLENEDIAMINE TRISODIC DISUCCINATE, HYDROXYACETOPHENONE, PHENOXYETHANOL) ~1 SKIN ACTIVE INGREDIENTS (SODIUM HYALURONATE, CERAMIDE BLEND, NIACINAMIDE) ~5 FILLER (ALUMINUM STARCH OCTENYSUCCINATE) Miscellaneous POLYMER (HYDROXYETHYLCELLULOSE) Miscellaneous AQUEOUS PHASE SOLVENT (GLYCERIN, PROPANEDIOL) ~6 WATER Miscellaneous (QS)

The base composition above was used to provide each of the comparative compositions listed in Table 5 below (identified by VAR 1 through VAR 15).

[TABLE 5] Various (comparative) compositions based on the inventive base composition Composition Filter system Other miscellaneous ingredients INVENTIVE 10% homosalate
5% octinoxate
5 % octisalate
2% octocrylene
8 % ZnO n/a VAR 1 10% homosalate
5% octisalate
7% octocrylene
6.3% ZnO ~2% glyceryl stearate (and) Peg-100 stearate
~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~5% cetearyl alcohol (and) ceteareth-20
~0.4% hydroxyethyl acrylate/sodium alkyldimethyl taurate copolymer
~3% caprylyl methicone VAR 2 15% homosalate
5% octisalate
7% octocrylene
6.3% ZnO ~2% glyceryl stearate (and) Peg-100 stearate
~4% (decreased)
~5% cetearyl alcohol (and) ceteareth-20
~0.4% hydroxyethyl acrylate/sodium alkyldimethyl taurate copolymer
~3% caprylyl methicone VAR 3 10% homosalate
5% octinoxate
3% octisalate
2% octocrylene
8% ZnO VAR 4 10% homosalate
5% octinoxate
5% octocrylene
8% ZnO ~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased) VAR 5 10% homosalate
5% octisalate
7% octocrylene
8% ZnO ~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased) VAR 6 10% homosalate
5% octinoxate
7% octocrylene
8% ZnO ~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3% dimethicone (increased) VAR 7 10% homosalate
5% octisalate
7% octocrylene
8% ZnO
(+3% BOS) includes IP reinforcer
~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3% dimethicone (increased) VAR 8 13% homosalate
5% octisalate
7% octocrylene
8% ZnO ~4% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3% dimethicone (increased) VAR 9 10% homosalate
5% octinoxate
7% octocrylene
8% ZnO
(+3% BOS) includes IP reinforcer VAR 10 13% homosalate
5% octinoxate
7% octocrylene
8% ZnO ~4.25% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3% dimethicone (increased)
0% charge (decreased) VAR 11 10% homosalate
5% octinoxate
5% octisalate
2% octocrylene
8% ZnO ~3.5% dimethicone (increased)
~4.25% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
0% charge (decreased)

UV filter: oily phase weight ratio = ~0.79; oil phase solvent:oil phase weight ratio (</=5%) = ~0.09 VAR 12 12% homosalate
5% octinoxate
5% octisalate
8% ZnO includes IP reinforcer

~4.25% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3.5% dimethicone (increased)
0% charge (decreased) VAR 13 13% homosalate
5% octinoxate
5% octisalate
8% ZnO ~4.25% cetearyl alcohol (and) behentrimonium methosulfate (decreased)
~3.5% dimethicone (increased)
0% charge (decreased)
~0.5% dicaprylyl ether

Note: ZnO quantities are an end asset, not RM quantity

EXAMPLE 3 : IP and critical wavelength (LOC) tests with inventive and comparative compositions

Each of the inventive and comparative compositions was evaluated for IP and LOC. As shown in Table 6 below, compositions that passed the test demonstrated a stable IP >/= 30 and an LOC >/= 370 nm.

[TABLE 6] IP and LOC results

Composition IP Critical wavelength
(λ _vs ) Pass/Fail INVENTIVE 31 370.1nm Success COMPARATIVE 30 370.1nm Success VAR 1 ND 369.4nm Failure VAR 2 ND 368.3nm Failure VAR 3 16 370.1nm Failure VAR 4 16 370.6nm Failure VAR 5 28 (standard deviation too high to reach IP 30) 370.9nm Failure VAR 6 15 370.6nm Failure VAR 7 17 373.4nm Failure VAR 8 17 373.2nm Failure VAR 9 28 373.3nm Failure VAR 10 21 373.2nm Failure VAR 11 25.42 (standard deviation too high to reach IP 30) ND Failure VAR 12 Without octocrylene 20 376.7nm Failure VAR 13 Without octocrylene 21 375.4nm Failure

It is evident that the inventive composition demonstrates an IP of 30 and a correct LOC while variations in the nature and quantity of UV agents, the quantity of oil phase solvent (dimethicone) and the inclusion or exclusion of filler (aluminum starch octenylsuccinate) affect one or both of the IP and LOC.

EXAMPLE 4: Structural stability of emulsion of inventive and comparative compositions

A panel of compositions was tested to verify IP and emulsion structural stability and processability. The results are presented in Table 7 below.

[TABLE 7] Inventive composition/comparative composition stability results Stability conditions tested INVENTIVE COMPARATIVE Stability for 1 week at 60°C (naked eye) Slight change in color of the emulsion; no syneresis (oil accumulation) Noticeable change in color of the emulsion; visible surface syneresis Stability for 1 week at 60°C (microscopic) Homogeneous emulsion, tight edges Slight emulsion inhomogeneity, loose edges Samples at 8 weeks at 5°C, 25°C, 37°C and 45°C The microscopic emulsion has a small particle size and is homogeneous The microscopic emulsion shows large irregular particles, especially at 37°C and 45°C Samples at 12 weeks at 5°C, 25°C, 37°C and 45°C Slight color change; all samples are smooth/homogeneous Noticeable color change; sample at 45°C demonstrated texture change and syneresis

According to the data collected for the inventive and comparative examples, it appears that the inventive composition demonstrates better short- and long-term stability (12 weeks), the stability being characterized by a minimal color change even at high temperature, no modification texture, oil accumulation and good emulsion homogeneity as demonstrated with and without microscopic evaluation.

EXAMPLE 5 : Linting Assessments : Removal of Octocrylene Increases Linting (Negative Effect)

In a clinical study, a panel of sensory experts evaluated the effects of the inventive compositions on a group of 15 Caucasian women with normal to combination skin types. Each testing panelist washes their face using a commercial cleanser. The skin balances for 10 minutes. Approximately 0.3 ml of moisturizer is distributed and applied to half of the face and the operation is then repeated for the other side using the same dose, applying on each side a dot on the chin, upper lip, the cheek, the side of the nose, the temple and two points on the forehead. The moisturizer is mixed until all of the product is absorbed, then the skin is assessed for any visible flaking during application and photographed; the timer is set for 2 minutes. After two minutes, a series of sweeping movements are applied to the skin surfaces with the back of the hand and the lint is assessed and photographed.

Table 8 shows the number of panelists experiencing linting with each composition tested before and after linting evaluation.

[TABLE 8] Results of lint tests for inventive/comparative compositions and VAR 12 and 13 Tester panelists experimenting with fluffing COMPARATIVE INVENTIVE VAR 11 VAR 12 VAR 13 Before fluffing gesture 0 0 0 2 1 After fluffing gesture 6 7 6 11 11

As noted above, the inventive composition is on par with the comparative composition with respect to linting. Additionally, the inventive composition has sensory attributes that are improved over the comparative composition regarding maximum effect upon application, consistency and overall shape upon initial application, and as shown in Table 7 , the inventive composition demonstrates improved stability without compromising sensory benefits.

Although the disclosure has been described with reference to a preferred embodiment, one skilled in the art will understand that various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of disclosure. Furthermore, many modifications can be made to adapt a particular situation or matter to the teachings of the disclosure without deviating from its essential scope. Therefore, it is intended that the disclosure is not limited to the particular embodiment disclosed as the best mode contemplated for making such disclosure, but that the disclosure includes all embodiments falling within the scope of the appended claims.

The organo-mineral hybrid sunscreen compositions and methods of the present invention may include, consist of, or consist essentially of the essential elements and limitations of the disclosure described herein, as well as any additional or optional ingredients, components or limitations described herein. or otherwise useful. The terms “comprising”, “having” and “including” are used in their broad and non-limiting sense. The term "inclusive" for a concentration range means that the limits of this range are included in the defined interval.

All percentages, parts and ratios herein are based on the total weight of the organo-mineral hybrid sunscreen composition of the present disclosure, unless otherwise noted.

All ranges and values disclosed herein are inclusive and combinable. For example, any value or point described here that falls within a range described here can be used as a minimum or maximum value to infer a subrange, etc. Additionally, all ranges provided are intended to include each specific range within the given ranges, as well as a combination of subranges in between. So a range of 1-5 specifically includes 1, 2, 3, 4, and 5, as well as subranges such as 2-5, 3-5, 2-3, 2-4, 1-4, etc.

As used herein, the term "at least one" is interchangeable with "one or more" and therefore includes individual components as well as mixtures/combinations.

The phrase "a mixture thereof" does not require that the mixture include all elements A, B, C, D, E and F (although all elements A, B, C, D, E and F may be included). Rather, it indicates that a mixture of two or more of elements A, B, C, D, E and F may be included. In other words, it is equivalent to the formulation "one or more elements selected from the group consisting of A, B, C, D, E, F, and a mixture of two or more of A, B, C, D , E and F”.

The term "viscosity" refers to the thickness of a fluid or composition and is a measure of the resistance of a fluid or composition to flow. Here, "viscosity" is synonymous with "dynamic viscosity" or "absolute viscosity", rather than "kinematic viscosity", and is measured using a rheometer in a method which is known to those skilled in the art. . Unless otherwise stated, viscosity measurements shown here are expressed in pascal-seconds (Pa·s).

The term "INCI" is an abbreviation of International Nomenclature of Cosmetic Ingredients, which is a system of names provided by the International Nomenclature Committee of the Personal Care Products Council to describe ingredients in personal care products.

The term "weight ratio" or "mass ratio", as used herein, refers to the amount of a substance in proportion to a mixture containing said substance, and is calculated by dividing the amount of said substance by the weight contained in the mixture by the weight of the mixture containing said substance. For example, a weight ratio of 0.4 for substance A in a mixture of A, B, and C indicates that the weight of substance A divided by the total weight of substances A, B, and C is 0.4.

Claims (10)

Organo-mineral hybrid sunscreen composition comprising:
an oil-in-water emulsion of aqueous and oily phases, comprising:

1. an oily phase comprising: at least one mineral UV filter comprising zinc oxide; an organic UV filter blend comprising ethylhexyl methoxycinnamate, ethylhexyl salicylate, octocrylene and homosalate;
2. an aqueous phase comprising: water; at least one solvent miscible in water and at least one polymer; And
3. at least one charge,

wherein the organo-mineral hybrid sunscreen composition has an IP of at least about 30 and a critical wavelength of at least 370 nm and wherein the organo-mineral hybrid sunscreen composition excludes one or several ingredients selected from the group consisting of methyl anthranilate, parabens and combinations thereof. The organo-mineral hybrid sunscreen composition of claim 1, wherein zinc oxide is present in an amount of at least about 8%; the organic UV filter mixture in which ethylhexyl methoxycinnamate is present at approximately 5%, ethylhexyl salicylate is present at approximately 5%, octocrylene is present at approximately 2% and homosalate is present at approximately 10% %, all quantities being by weight, based on the weight of the composition. The organo-mineral hybrid sunscreen composition according to claim 1, the organo-mineral hybrid sunscreen composition further comprising at least one oil phase solvent, and at least one surfactant, wherein the weight ratio of the UV filters on the total amount of the oil phase is approximately 80%, based on the total weight of the UV filters and the total weight of the oil phase, and wherein the weight ratio of the oil phase solvent to the total amount of the oil phase is less than or equal to about 5%, based on the total weight of the oil phase solvent and the total weight of the oil phase. An organo-mineral hybrid sunscreen composition according to claim 3, wherein at least one oil phase solvent comprises dimethicone, the at least one surfactant is selected from the group consisting of cationic surfactants including quaternary ammonium compounds, in which the at least one water-miscible solvent is selected from the group consisting of monoalcohols, diols, polyols and combinations thereof, and in which the at least one polymer is selected from the group consisting of celluloses, gums, hydrophilic colloids and combinations thereof, and wherein the at least one filler is selected from starches. An organo-mineral hybrid sunscreen composition according to claim 3, wherein the at least one surfactant comprises cetearyl alcohol (and) behentrimonium methosulfate, the at least one water-miscible solvent comprises glycerin and propanediol, the at least one polymer comprises hydroxyethyl cellulose and the at least one filler comprises aluminum starch octenyl succinate. The organo-mineral hybrid sunscreen composition of claim 1, wherein the organo-mineral hybrid sunscreen composition excludes menthyl anthranilate. Organo-mineral hybrid sunscreen composition according to claim 1, further comprising one or a combination of additives selected from the group consisting of solvents, IP enhancers, humectants, waxes, skin care active ingredients, preservatives, correctors pH, chelating agents, cooling agents, fragrances, dyes, pigments and combinations thereof. A composition according to claim 1, wherein the organo-mineral hybrid sunscreen composition does not show signs of phase separation and/or does not become non-homogeneous after up to 12 weeks at room temperature in the range of approximately 5°C up to and including approximately 45°C, and retains structural emulsion stability, with minimal color change at 60°C for at least one week. An organo-mineral hybrid sunscreen composition according to claim 1, wherein

1. in the oil phase, the organo-mineral hybrid sunscreen composition further comprises at least one oil phase solvent comprising dimethicone, and at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate, and wherein the at least one mineral UV filter comprising zinc oxide is present in an amount which is at least about 8%; the organic UV filter blend includes approximately 5% ethylhexyl methoxycinnamate, approximately 5% ethylhexyl salicylate, approximately 2% octocrylene, and approximately 10% homosalate, all the quantities being by weight, based on the weight of the composition;
2. in the aqueous phase, the at least one water-miscible solvent comprising glycerin and propanediol; and the at least one polymer comprising hydroxyethylcellulose; And
3. the at least one filler comprising an aluminum starch octenyl succinate.

Organo-mineral hybrid sunscreen composition according to claim 9, in which:

1. the at least one oil phase solvent comprising dimethicone is present in an amount less than or equal to approximately 2%, and the at least one surfactant comprising cetearyl alcohol (and) behentrimonium methosulfate is present at approximately 4, 5%;
2. glycerin is present at approximately 3% and propanediol at approximately 3%; and hydroxyethylcellulose at approximately 0.5%; And
3. aluminum starch octenysuccinate is present at approximately 0.5%

all amounts being by weight, based on the weight of the composition, wherein the organo-mineral hybrid sunscreen composition further comprises one or a combination of additives selected from the group consisting of solvents, IP enhancers , humectants, waxes, skin care actives, preservatives, pH correctors, chelating agents, cooling agents, fragrances, dyes, pigments and combinations thereof, and in which the organo-mineral hybrid sunscreen composition excludes methyl anthranilate, and wherein the organo-mineral hybrid sunscreen composition does not show signs of phase separation, and/or does not become non-homogeneous after a period of up to 12 weeks at a temperature in range from approximately 5°C to approximately 45°C, and retains structural emulsion stability, with minimal color change at 60°C for at least one week.