FR3117001A1 - Device and method for cleaning the skin and/or keratin fibers - Google Patents

Abstract

Device and method for cleaning the skin and/or keratin fibers Device (1) for packaging and dispensing a composition for cleaning the skin and/or keratin fibers and/or the mucous membranes and/or the nails, comprising: - a composition, in particular cosmetic and non-therapeutic, for the care, hygiene and/or cleansing of the skin and/or keratin fibers and/or mucous membranes and/or nails, in the form of an aqueous solution , - a body (2) forming a reservoir (4) to contain the composition, the body (2) comprising at least one supply orifice (5) to allow the composition to exit from said body (2), - at least one sole (10; 10a, 10b) intended to be in contact with the skin and/or the keratin fibers and/or the mucous membranes and/or the nails, fixed to the body (2) and having an outer surface (15) on which are provided cleaning reliefs (7) and at least one dispensing opening (18), the opening distribution port (18) and said at least one supply port (5) being arranged so as to allow the distribution of the composition. Figure for abstract: Fig. 2

Description

Device and method for cleaning the skin and/or keratin fibers

The present invention relates to cleaning the skin and/or keratinous fibres, such as the hair or the beard, in particular human but also animal, in particular the body hair, and/or the mucous membranes and/or the nails. In particular, the invention relates to a cleaning device containing a cleaning composition as well as a method for cleaning the skin and/or keratin fibers such as the hair or the beard and/or the mucous membranes and/or the nails, using such a device.

The difficulty of being able to access running water or to have a large volume of water is today a reality for many people in the world and this difficulty could increase in the coming decades in view of the change climatic.

In this context, it is necessary to have equipment that allows us to consume less or even very little water for common tasks for which we usually use a little or a lot of water. This is the case of body washing, for which we take baths or showers, consuming a large amount of water.

It thus appears necessary to make it possible to greatly reduce the use of water for cleaning the skin and/or keratin fibres.

Moreover, the heating of a large quantity of water is a source of CO ₂ emission if the energy source is not renewable, the reduction of CO ₂ emission is therefore desirable.

The main objective of the invention is thus to propose a new mode of body cleansing, for the skin and/or the keratin fibres, capable of effectively replacing conventional aqueous body cleansing, such as, for example, the shower, especially hot, or bath, especially hot.

As detailed below, the proposed solution consists of providing a new cleaning device containing a cleaning composition, the tool being durable and adapted to precisely eliminate the use of a large quantity of water for cleaning the body and also making available a process for cleaning the body based in particular on the implementation of this device.

The invention thus relates, according to one of its aspects, to a device for packaging and dispensing a composition for cleaning the skin and/or keratin fibers and/or mucous membranes and/or nails, including:

- a composition, in particular cosmetic and non-therapeutic, for the care, hygiene and/or cleansing of the skin and/or keratin fibers and/or mucous membranes and/or nails, in the form of a solution aqueous comprising at least:

(i) all or part of a lysate, isolated or not from a fermentation medium of a non-pathogenic and aerobic proteobacterium or a (glyco)oligopeptide fraction isolated from such a lysate,
(ii) at least one mucopolysaccharide, in particular weighing more than 10kD,
(iii) at least one hydrating agent distinct from (i) and (ii) and chosen in particular from glycerol, aminoglycerol, urea, their salts and their mixtures,
(iv) at least one electrolyte,
(v) water and
(vi) where applicable, at least one cosmetic active ingredient distinct from (i), (ii) and (iii),

- a body forming a reservoir to contain the composition, the body comprising at least one supply orifice to allow the composition to exit from said body,

- at least one sole intended to be in contact with the skin and/or the keratin fibers and/or the mucous membranes and/or the nails, fixed to the body and having an outer surface on which cleaning reliefs are provided and at least one dispensing opening, the dispensing opening and said at least one supply orifice being arranged so as to allow the composition to be dispensed.

This new device containing the composition makes it possible to carry out cleaning, including for example make-up removal or scrubbing, which is rapid, economical, independent of a shower, on all or part of the body or keratin fibres, in particular hair, eyelashes, eyebrows or beard and/or mucous membranes and/or nails.

By “keratin fibres”, one understands, according to the invention, the eyelashes, the eyebrows, the body hair, the beard, the scalp and/or the hair.

By "the skin" is meant the whole of the skin of the body, and preferably, the skin of the face, of the neckline, of the neck, of the arms and forearms, even more preferably still, the skin of the face, especially the forehead, nose, cheeks, chin, eye contour.

By “cleansing” of the skin and/or keratin fibers and/or mucous membranes and/or nails, is meant any form of cleaning including washing, bathing, shampooing, exfoliation, make-up removal, massage, brushing, combing, or any other action or gesture performed on the skin and/or the keratin fibers and/or the mucous membranes and/or the nails with the device using the cleaning reliefs and the dispensed composition.

Thanks to the invention, there is a new device for cleaning the skin and/or keratinous fibers such as human hair or beard or even animal hair and/or mucous membranes and/or nails, long-lasting and adapted precisely to eliminate the use of a large quantity of water for cleaning the skin and/or keratin fibres.

Indeed, such a device makes it possible to carry out cleaning while requiring little water, in particular only the water present in the composition, which makes it possible to dispense with the presence of a running water point or a large quantity of water for cleaning the skin and/or the keratin fibers and/or the mucous membranes and/or the nails of a person. Such a device can thus be useful for washing, shampooing, removing make-up, scrubbing for a person with little or no mobility, and/or each time there is a shortage of water or one wishes to save it. Indeed, the cleaning reliefs make it possible to carry out, with the composition dispensed from the reservoir, an autonomous and effective cleaning, implementing a gesture of friction and massage using the cleaning reliefs and without requiring the addition of water apart from the cleansing composition, in the manner of the toilet made by felines, such as cats, and other living beings using their tongue and their saliva.

The cleaning reliefs can be configured to allow massaging, rubbing, brushing of the skin and/or keratin fibers and/or mucous membranes and/or nails with the sole.

All or part of the cleaning reliefs may comprise studs.

In this case, at least part of the spikes can be configured to imitate the papillae of the tongue of a feline, in particular of a cat.

By “pins configured to imitate the papillae of the tongue of a feline”, is meant pins imitating the shape of a papilla of the tongue of a feline, being for example curved in a manner similar to that of a papilla. Of course, certain parameters of this shape can be adapted to better adapt in particular to human hair or animal fur. In particular, the pimples of the sole can be harder and/or longer than the papillae. This can make it possible to ensure effective brushing of human hair, for example, by going to the scalp which can thus also be massaged.

The cleaning reliefs may comprise at least one sipe, in particular a plurality of sipes, extending in particular substantially orthogonally from the outer surface of the sole.

The sole is preferably removably attached to the body.

As for the composition, it has the originality of being bio-inspired insofar as its composition is developed with regard to that of saliva.

For the record, saliva is a very dilute fluid, made up of more than 99% water. Its normal saliva pH is 6 to 7. It is made up of a variety of electrolytes, including sodium, potassium, calcium, magnesium, bicarbonate, and phosphate ions. Also present in saliva are immunoglobulins, proteins, enzymes, mucins and nitrogenous species, such as urea and ammonia. Bicarbonates, phosphates and urea act to modulate the pH and buffering capacity of saliva. Macromolecular proteins and mucins serve to scavenge, aggregate and/or attach oral microorganisms and contribute to the metabolism of dental plaque. Calcium, phosphate and protein ions in particular modulate demineralization and remineralization. As for immunoglobulins, proteins, and enzymes, they contribute to the antibacterial action. Finally, as a seromucous coating, saliva lubricates and protects the oral tissues.

Against all expectations, the inventors have observed that a specific composition, developed on the model of saliva, makes it possible to provide effective cleaning of keratin materials provided that it is used with a particular cleaning tool.

In addition, with regard to its components, the washing composition according to the invention provides lubricating, film-forming benefits for the skin and/or the keratin fibers, in particular the hair or the beard, and/or the mucous membranes and/or the nails. and generates a new sensory perception for users, such as a sensory feeling of softness, silkiness, pleasantness.

According to a variant embodiment, the composition contains all or a fraction of lysate isolated from its fermentation medium.

According to another alternative embodiment, the composition contains said whole lysate in a complete fermentation medium.

In particular, the bacterium belongs to the genus Vitreoscilla sp . More particularly, the bacterium of the composition is a Vitreoscilla filiformis strain. It is preferably the bacterium Vitreoscilla filiformis and more preferably the strain Vitreoscilla filiformis ATCC 15551.

The composition may contain at least one mucopolysaccharide extracted from seaweed, in particular chosen from carrageenans, alginates, ulvans, fucoidanes, chitosan, chitin, their salts, their extracts and their mixtures and in particular containing at least one carrageenan in particular derived from Chondrus crispus or Kappaphycus alvarezii.

The composition may contain a single electrolyte or a mixture of several electrolytes chosen from alkaline-earth metal salts and in particular calcium salts, alkali metal salts and in particular sodium and potassium salts, as well as salts magnesium, manganese and carbonates, bicarbonates, sulphates, phosphates bromides, chlorides and fluorides.

The composition of the device according to the invention comprises for example at least 50% by weight and in particular at least 80% by weight of an aqueous medium relative to its total weight.

The composition, which further comprises at least one electrolyte, is in the form of an aqueous solution.

Thus, the composition of the device according to the invention containing water, in the form of an aqueous solution, can be used as a body cleansing product such as a shower product, a bath product, a for cleaning the hands, such as a product for cleaning keratin fibres, in particular the hair or the beard, such as a shampoo, or also as a product for cleaning the face, for example as a product for removing make-up from the eyes, the face or the lips, or else as a product for cleaning or care of mucous membranes and/or nails.

In a particular embodiment, the composition contains at least
- at least the oligopeptide fraction isolated from a lysate of a fermentation medium of a proteobacteriumVitreoscilla filiformis, in particular the strainVitreoscilla filiformisATCC 15551,
- approximately 0.05% by weight of at least one mucopolysaccharide, in particular at least one carrageenan, relative to its total weight,
- approximately 15% by weight of at least one moisturizing agent chosen from glycerol, aminoglycerol, urea, their salts and mixtures thereof relative to its total weight,
- about 10% by weight of desalinated seawater compared to its total weight And
- approximately 74% by weight of water, distinct from seawater, in relation to its total weight.

A further subject of the present invention, according to another of its aspects, in combination with the above, is a process for cleaning the skin and/or keratin fibers and/or the mucous membranes and/or the nails using a device as defined above, the method comprising the following steps:

1. Step a: cause the composition to be dispensed through said at least one dispensing opening,
2. Step b: bringing the dispensed composition and the cleansing reliefs into contact with the skin and/or the keratin fibers and/or the mucous membranes and/or the nails,
3. Step c: rub, massage, brush and/or comb the skin and/or the keratin fibers and/or the mucous membranes and/or the nails using the cleansing reliefs.

When one or more lamellae are present on the sole, it is still possible to scrape the skin.

The present invention also relates, according to another of its aspects in combination with the above, to a non-therapeutic cosmetic process for exfoliating the skin comprising the application of at least one cosmetic composition using the device according to the invention. .

The present invention also relates, according to another of its aspects in combination with the above, to a non-therapeutic cosmetic process for removing make-up from the eyelashes, lips and/or skin, in particular from the face, comprising the application of at least a cosmetic composition using the device according to the invention on said area to be removed.

Device (excluding composition)

The device advantageously comprises at least one valve making it possible to close or not close said at least one supply orifice.

The reservoir can thus be closed by closing the supply orifice, which makes it possible to prevent the composition from flowing out of the reservoir in an uncontrolled manner, which also makes it possible to prevent any leakage of composition. When desired, in particular when using the device, the valve can be opened, making it possible to clear the supply orifice which is no longer closed off, in order to allow the composition to pass out of the reservoir. This opening can be automatic and result from the pressurization of the cleaning composition.

The body may comprise at least one wall delimiting a volume forming the reservoir, at least part of said wall being elastically deformable.

In this case, said at least one valve can be configured so as to allow the retention of the composition in the reservoir in the absence of pressure exerted on said at least one elastically deformable part of the wall and the exit of composition from the reservoir when pressure is exerted on said at least one elastically deformable part of the wall. The valve can thus be closed at rest, and open under the effect of the pressure exerted by the user when the latter presses on the body to reduce its internal volume.

Said at least one valve has, for example, an annular-shaped base and an obturator fixed to the base and comprising at least two elastically deformable membranes cooperating in the absence of pressure so as to prevent any exit of the composition from the reservoir and defining between they open when pressure is exerted on the elastically deformable part of the wall of the body to allow the composition to exit from the reservoir.

The device preferably comprises at least one retaining element arranged to cause the valve to cooperate with the supply orifice, the retaining element forming, for example, a ring of external diameter substantially equal to that of said supply orifice and of diameter inside substantially equal to the outside diameter of a part of the valve, so as to maintain the valve externally and to cooperate internally with the supply orifice.

In the case where the sole is removably fixed to the body, at least two different soles can be provided, being able to be fixed alternately to the body. The device can thus for example comprise a sole provided for cleaning the skin and a sole provided for cleaning the keratin fibres. In the latter case, the cleaning reliefs of the sole provided for cleaning the skin may be at least partly different from the cleaning reliefs of the sole provided for cleaning keratin fibres.

The body may be made of at least one elastically deformable material, in particular an elastically deformable material, for example chosen from the group consisting of a thermoplastic elastomer (TPE), a high performance elastomer (HPE), in particular high performance polyurethane elastomer or high performance thermoplastic elastomer, a polyurethane, a silicone and a polyamide, a biocellulose and a mushroom mycellium. The material chosen is preferably chosen from biopolymers or bioplastics, that is to say comprising biodegradable polymers, polymers from renewable sources, for example biosourced (obtained by a process from plant material), or polymers belonging to these two categories. The material chosen is preferably a recyclable or reusable polymer. The material can be chosen, for example, from the range of biopolymers marketed under the name Terraprene®, thermoplastic elastomeric compounds (TPE), by the company FKUR Polymers or even from the range of thermoplastic elastomers (TPE) containing raw materials from plant products. renewables marketed under the name Dryflex® Green by the company Hexpol or in the range of biosourced thermoplastic elastomers (BioTPE) marketed by the company NaturePlast.

The or each sole may be made of at least one elastically deformable material, in particular an elastically deformable material, for example chosen from the group consisting of a thermoplastic elastomer (TPE), a high performance elastomer (HPE), in particular a high performance polyurethane elastomer. performance or high performance thermoplastic elastomer, polyurethane, silicone and polyamide, biocellulose and mushroom mycellium. The material chosen is preferably chosen from biopolymers or bioplastics, that is to say comprising biodegradable polymers, polymers from renewable sources, for example biosourced (obtained by a process from plant material), or polymers belonging to these two categories. The material chosen is preferably a recyclable or reusable polymer. The material can be chosen, for example, from the range of biopolymers marketed under the name Terraprene®, thermoplastic elastomeric compounds (TPE), by the company FKUR Polymers or even from the range of thermoplastic elastomers (TPE) containing raw materials from plant products. renewables marketed under the name Dryflex® Green by the company Hexpol or in the range of biosourced thermoplastic elastomers (BioTPE) marketed by the company NaturePlast.

The materials constituting the body and the sole may be identical or different, in particular as regards their elasticity.

The sole provided for cleaning the skin or at least the reliefs for cleaning this sole can be more flexible than the sole provided for cleaning keratin fibres, or at least than the reliefs for cleaning of this sole.

When the sole is removably attached to the body, the sole advantageously comprises, on an inner surface opposite the outer surface, a fixing relief, the body having on an outer face a complementary fixing relief capable of cooperating, in particular mechanically, with sole fixing relief for fixing the sole to the body.

In this case, the complementary relief for fixing the body can at least partially delimit a zone comprising said supply orifice(s).

Still in this case, the complementary relief for fixing the body comprises for example a bead extending towards the outside of the body with an at least partially closed contour, the contour of the bead having a shape similar to that of the outer contour of the relief of fixing of the sole, which fixing relief can form a rim configured to match the shape of the bead.

Thanks to the presence of fixing reliefs on the sole and on the body, capable of cooperating with each other, it is easy to secure and then separate the sole and the body, in particular when the sole and/or the body is/are made ( s) in at least one elastically deformable material at least at the fixing relief.

To facilitate the removal of the sole, the latter may comprise at least one tab, in particular two tabs, allowing the sole to be gripped in order to remove it from the body, when desired. This or these tabs may be present at at least one longitudinal end of the sole, in particular extending from an inner surface of the sole.

The body preferably comprises a plurality of supply orifices, in particular five supply orifices, to allow the composition to come out, the said supply orifices being for example arranged in a row, in particular provided to extend substantially middle of the sole when the latter is attached to the body. The supply port(s) are through.

In the case where the supply orifices are arranged in a row and in the case where the sole extends along a curved longitudinal axis, said row may be substantially curved with a curvature similar to a curvature of said curved longitudinal axis of the sole .

The dispensing opening can be formed on the outer surface of the soleplate or in one of the cleaning reliefs.

In the case where the cleaning reliefs comprise spikes, at least one spike may have a passage leading to the dispensing opening.

In this case, the passage of said at least one spike which opens onto the dispensing opening can pass through the spike from one end connected to the outer surface of the sole to a free end, the free end comprising the opening for dispenser for dispensing the cleaning composition.

All or part of the pimples may have a shape with a diameter which decreases from the end connected to the outer surface of the sole to the free end.

Said at least one sole comprises, for example, spikes of at least a first shape and spikes of at least a second shape, differing in particular from the first shape by the diameter, the shape of the free end, the length, and / or the longitudinal axis, straight or curved, along which the spikes extend between their end connected to the sole and their free end.

At least some of the spikes, or even all of the spikes, of the sole, in particular the sole provided for cleaning keratin fibers, may have a curved shape, the longitudinal axis of said spike(s) then being curved.

At least part of the studs, in particular all of the studs, of the sole, in particular the sole provided for cleaning the skin, may have a rectilinear shape, in particular of substantially conical or frustoconical shape.

When the cleaning reliefs comprise at least one lamella, at least one region of the outer surface of the sole, in particular of the sole provided for cleaning the skin, may be devoid of studs, said region being for example provided with said au at least one lamella, in particular a plurality of lamellae, extending substantially orthogonally from said outer surface. In this case, the cleaning reliefs comprise, in a region of the outer surface of the sole, spikes and, in at least one other region of the outer surface of the sole, slats.

Such strips can have a skin-scraping effect, for example to remove the remaining composition and/or dead skin cells, make-up to be removed or impurities. The sipes can be arranged parallel to each other and/or parallel to the outer edge or contour of the outer surface of the sole in said region. It is understood that the parallelism can relate to curved lines which are thus equidistant along their entire length. The studs can extend in rows, for example in the extension of the sipes, when present, distributed over another region of the sole.

The sole may extend along a curved longitudinal axis, said body then being able to present, at least in a part intended to cooperate with the sole, a similar curved shape.

Such a shape can be ergonomic for handling and using the device.

The body can extend from a lower end to an upper end, along a longitudinal axis, preferably curved, the body comprising a base portion, notably comprising a gripping part, including the lower end, and a portion upper comprising the upper end, a width of the base portion being greater than a width in the upper portion, the width of the upper portion preferably decreasing in the direction of the upper end.

The upper portion may comprise the part of the body which cooperates with the sole and may comprise, where appropriate, at least a part of said complementary fixing relief when the sole is removably fixed to the body.

The body may comprise in a rear part the gripping part and in a front part, opposite to the rear part, said complementary fastening relief.

The body preferably has an ergonomic shape, for example adapted to the user, in particular in the gripping part.

Furthermore, the body advantageously comprises an opening for filling the composition, the device comprising an at least partially removable stopper arranged to close said filling opening.

In this case and in the case where the body comprises a base portion having a lower end, the filling opening is preferably located at a lower end of the body, in particular at a lower end of the base portion of the body.

The filling opening can be defined by a skirt extending inside or outside the tank.

An adapter piece can be interposed between the plug and the body so as to allow the plug and the body to cooperate with each other. For example, the adapter piece can be mounted by force or by snap-fastening on the skirt extending outside the tank and defining the filling opening. The adapter piece may comprise a skirt extending substantially parallel to the skirt of the body and having an external thread capable of cooperating with a corresponding thread present on an internal skirt of the cap in order to be able to close the filling opening.

The lower end of the device may be flat and wide enough to be able to rest on a flat support and allow the device to be held in place without requiring the intervention of a person.

The body may include an air intake orifice. Such an orifice may be provided with a valve, in particular a valve similar to that fitted to the supply orifice or orifices for the outlet of the cleaning composition.

When the body has an air intake orifice provided with a valve, said valve can be arranged to open when the user stops pressing on the body so as to allow air to enter. The body can then return to its original shape.

The shape and dimensions of the device are preferably adapted for good handling by the user. The total height of the body of the device may in particular be between 5 cm and 20 cm, in particular between 7 cm and 13 cm. The capacity of the tank can be between 3cl and 20cl approximately, in particular between 4 cl and 15cl. The width of the device may be between 3 cm and 8 cm, in particular approximately 5 cm. The depth, from front to back, of the device may be between 3 cm and 10 cm, for example, in particular between 7 and 9 cm, this depth possibly depending on the sole which is fixed to the body.

Composition

As specified above, the composition of the device according to the invention combines at least all or part of a lysate, isolated or not, of a fermentation medium of a proteobacterium or a specific fraction of such a lysate, with at least one mucopolysaccharide, at least one auxiliary hydrating agent, at least one electrolyte and water.

Bacteria fermentation medium lysate

A lysate commonly designates a material obtained following the destruction or dissolution of biological cells by a phenomenon known as cell lysis, thus causing the release of intracellular and cellular biological constituents naturally contained in the biological cells considered.

Within the meaning of the present invention, the term lysate designates the entirety of the lysate obtained by lysis of the proteobacteria concerned. A lysate is therefore formed from all of its intracellular biological constituents, in particular its metabolites and the constituents of the cell walls and membranes generated during its cell lysis.

Within the meaning of the invention, the term “metabolite” designates any substance resulting from the metabolism of the microorganism considered according to the invention.

This cell lysis can be accomplished by various technologies, such as for example osmotic shock, thermal shock, ultrasound, or even under mechanical stress of the centrifugation type. More particularly, this lysate can be obtained according to the technology described in US patent 4,464,362.

As specified above, according to a particular embodiment, a composition of the device according to the invention contains all or only part of a lysate of the fermentation medium or else of the biomass of a proteobacterium. Thus, a part of the lysate can be isolated from the whole lysate by a centrifugation method. It may for example be the supernatant of the lysate.

By way of non-limiting illustration of the non-pathogenic and aerobic proteobacteria suitable for the invention, mention may in particular be made of the bacterium(ies) belonging to the genus Vitreoscilla sp, to the genus Sphingomonas sp, or to the genus Pseudoalteromonas sp.

More specifically, the bacterium is a non-synthetic filamentous bacterium as defined according to the classification of Bergey's Manual of Systematic Bacteriology (Vol. 3, sections 22 and 23, 9th edition, 1989), belonging to the genus Vitreoscilla sp . More specifically, it is the bacterium Vitreoscilla filiformis .

In a particular embodiment, the bacterium is the Vitreoscilla filiformis strain , preferably the Vitreoscilla filiformis ATCC 15551 strain. patent WO-A-94-02158 or patent application WO2008/138839.

According to another particular variant, the composition of the device according to the invention contains the lysate, in a complete fermentation medium.

Within the meaning of the invention, the expression “lysate in a complete fermentation medium” means that the lysate is present, in the composition of the device according to the invention containing it, formulated in its original complete culture medium, which Complete culture medium is the medium in which the bacteria have been cultured until after the microbial growth phase leading to the use of the nutrient substrates initially present in the culture medium.

More specifically, this "complete fermentation medium" is intended to designate a medium resulting from the culture process having been used for the growth and cell lysis of the bacterium, said medium having not otherwise undergone any additional manipulation aimed at separating and/or removing all or part of its non-aqueous constituents.

More particularly, the composition contains the lysate of microorganisms and all or part, in terms of quantity, of the culture medium having served for the fermentation of said bacterium and in which it was carried out consecutively to its cell lysis (i.e. complete fermentation medium ). This so-called complete fermentation medium therefore contains the cytoplasmic and cytosolic fractions, the cell wall fragments and the metabolites formed and/or released during the cell lysis of said microorganism and all the biological entities likely to be generated and released spontaneously by the bacterium during its fermentation process and therefore already present in the fermentation medium before its cell lysis.

Thus, in a particular embodiment, a composition of the device according to the invention contains the lysate of the Vitreoscilla filiformis strain, preferably the Vitreoscilla filiformis strain ATCC 15551, in its complete fermentation medium. This lysate in complete medium can in particular be obtained according to the protocol described in patent application EP 2 830 588.

According to yet another particular variant, a composition of the device according to the invention contains the (glyco)oligopeptide fraction isolated from a lysate of a biomass also called the fermentation medium of a proteobacterium.

Within the meaning of the invention, the expression (glyco)oligopeptide fraction covers a fraction containing at least one oligopeptide and/or at least one glycooligopeptide.

For the purposes of the present invention, oligopeptide means a heterooligopeptide and glycooligopeptide means an oligopeptide covalently linked to a glycosylated mono- or oligo-carbohydrate radical, generally of small size. The mass of the glycosylated part of a glycooligopeptide can vary from 5 to 40% of the molecular mass of the whole glycooligopeptide.

This oligopeptide fraction can be obtained via a process consisting of:

- the culture of at least one proteobacteria on a fermentation medium under conditions conducive to the proliferation of said bacterium, and

- a centrifugation step, and

- possibly adjusting the pH, and

- the enzymatic digestion of the pellet resulting from the centrifugation of said bacteria in said fermentation medium.

The oligopeptide fraction within the meaning of the invention thus designates in particular the fraction resulting from the digestion of the pellet, resulting from centrifugation, which is optionally adjusted to a given pH and subsequently treated with a carbohydrase enzyme and a protease enzyme.

To isolate the oligopeptide fraction of a proteobacterium(s) from a Vitreoscilla filiformis strain, reference may be made in particular to the description of patent application WO2018/108973. More precisely, the oligopeptide fraction thus isolated consists of 30 to 50% of oligopeptides, between 1% and 10% of amino acids and of 10 to 20% of a mixture of oligosaccharides and monosaccharides. Generally, oligopeptides have a molecular weight between 200 and 3 kDa, with a peptide distribution centered on the 200-800 Da region. In particular, the oligopeptides are peptides between 2 and 7 amino acids on average. Glutamic acid, glutamine, histidine and arginine constitute at least 15% of said 1 to 10% amino acids. Preferably, the oligosaccharides are chosen from stachyose, sucrose, glucose, fructose and thehalose.

Mucopolysaccharide

Mucopolysaccharides are a class of polysaccharides, also called glycosaminoglycans, composed of amino sugars chemically linked in repeating units to form linear, unbranched polymer-like compounds.

These compounds are very particularly advantageous for providing long-lasting hydration to the skin or to the scalp.

In particular, the mucopolysaccharides are present in the compositions of the device according to the invention in a form distinct from a lysate.

More particularly suitable for the invention are mucopolysaccharides with a weight greater than 10 kD.

The mucopolysaccharides suitable for the invention may in particular be chosen from polysaccharides extracted from seaweed, in particular green, red or brown, and most particularly from carrageenans, alginates, ulvans, fucoidans, chitosan, chitin, their salts and mixtures thereof.

A composition of the device according to the invention may thus contain, as mucopolysaccharides, at least one alginate.

Alginic acid is a natural substance extracted from brown algae or bacteria. Alginic acid forms water-soluble salts (alginates) with alkali metals, such as sodium, calcium, potassium, lithium; (C1-C8) alkylamines and (C1-C8) alkylammoniums such as methylamine, ethanolamine, diethanolamine, triethanolamine.

A composition of the device according to the invention may also contain, as mucopolysaccharides, at least one ulvan, one of its salts or extracts. Ulvans are sulfated anionic polysaccharides containing rhamnose obtained from green algae belonging to the order Ulvales. Ulvans are water-soluble sulfated anionic polysaccharides that are localized in the cell wall. The ulvan according to the invention preferably comes from Ulva lactuca. Ulvane can be implemented in the form of the extract called “OligoUlvane” which can be obtained according to patent FR 3 075 644.

A composition of the device according to the invention may also contain, as mucopolysaccharide, at least one fucoidan, one of its salts or extracts. Fucoidan, extracted from seaweed, is a generic term for a polysaccharide that includes sulfated fucose as a saccharide component. It may in particular be the commercial product Matrigenics distributed by the company Codif.

A composition of the device according to the invention may also contain, as mucopolysaccharide, at least one (co)polymer of glucosamine chosen from chitosan and its salts. Chitosan is a polysaccharide composed of D-glucosamine and N-acetyl-D-glucosamine. It can be implemented as such or in the form of one of its salts, such as salts with a carboxylic acid comprising from 1 to 6 carbon atoms such as acetic acid, thioglycolic acid, adipic acid, ascorbic acid, formic acid, glycolic acid and lactic acid. This chitosan can in particular be implemented in the form of the commercial product Kionutrime distributed by the company Kytozyme.

In particular, a composition of the device according to the invention contains, as mucopolysaccharide, at least one carrageenan or one of its salts.

Carrageenans are sulfated and linear polysaccharides, comprising long galactan chains formed from disaccharide units, which constitute the cell walls of various red algae, from which they can be obtained. Among these red algae, mention may be made, without limitation, of Kappaphycus alvarezii, Eucheuma denticulatum, Eucheuma spinosum, Chondrus crispus, Betaphycus gelatinum, Gigartina skottsbergii, Gigartina canaliculata, Sarcothalia crispata, Mazzaella musceapellata, Mastnocariformatus cordiforme, Irocariformata cordiforme, Irrocariformata cordiforme, Mazzaella musceapusellatus and Irocariformatus cordiforme.

The carrageenans which are particularly suitable for the invention are carrageenans of lambda, kappa or iota form, their hybrids and their mixtures in all proportions. It can therefore be a single carrageenan or a mixture of carrageenans.

More specifically, these carrageenans are chosen from the following compounds:

- Iota carrageenan;

- Kappa carrageenan;

- Lambda/kappa carrageenan mixture notably marketed under the name Satiagel and

- Lambda carrageenan.

The carrageenans of the present invention can be used in acid form or in salified form. Acceptable salts which may be mentioned without limitation include lithium, sodium, potassium, calcium, zinc and ammonium salts or salts obtained with an organic base counterion, such as a primary alkylamine , secondary or tertiary (C1-C6), in particular triethylamine or butylamine or even the basic form of amino acids such as that of arginine and lysine for example.

The molecular weight of the carrageenans useful for the present invention is generally between 10×10 ³ and 100×10 ⁶ Da and in particular between 15×10 ³ and 10×10 ⁵ Da.

The carrageenans which can be used in particular in the invention mainly comprise lambda forms, or are present in lambda form. The term “predominantly” means that the percentage of this type of chain in the composition of the product is greater than or equal to 50%, this proportion possibly being greater than or equal to 80% in certain embodiments.

Carrageenans derived from Chondrus crispus or Kappaphycus alvarezii are particularly suitable.

The carrageenans extracted from Chondrus crispus may in particular be those marketed by the company Cargill under the respective names Satiagum UTC 30 Carrageenan lamda Cargill and Satiagum UTC 10 Carrageenan lamda Cargill.

A composition of the device according to the invention, in an aqueous pharmaceutical formulation, may comprise from 0.01 to 5% and preferably 0.02 to 0.1% by weight of mucopolysaccharide(s) and in particular of carrageenan(s) relative to the total weight of the composition.

The mucopolysaccharide(s) according to the invention is combined with at least one additional moisturizing agent chosen in particular from glycerol, aminoglycerol, urea, their salts and their mixtures.

The hydrating agent is said to be ancillary because it is distinct from a lysate or a mucopolysaccharide as required according to the invention and detailed above.

In particular, a composition of the device according to the invention comprises one or more mucopolysaccharide(s) and one or more additional hydrating agents, in particular in a hydrating agent(s)/mucopolysaccharide(s) weight ratio ranging from 50 to 1000 and preferably from 100 to 500 and especially from 200 to 400.

The amount of auxiliary moisturizing agent in a composition of the device according to the invention, in aqueous galenic formulation, can vary from 1 to 30%, preferably from 5 to 20% by weight relative to the total weight of the composition.

Electrolytes

A composition of the device according to the invention further comprises one or more electrolytes.

As electrolytes which can be used in the composition of the device according to the invention, mention may be made more particularly of alkaline-earth metal salts and in particular calcium salts, alkali metal salts and, for example, sodium and potassium salts, as well as as magnesium and manganese salts, and mixtures thereof.

The ions constituting these salts can be chosen, for example, from carbonates, bicarbonates, sulphates, phosphates, sulphonates, glycerophosphates, borates, bromides, chlorides, fluorides, nitrates, acetates, hydroxides, persulfates as well as α-hydroxy acid ions (citrates, tartrates, lactates, malates) or fruit acids, β-hydroxy acid ions (salicylates, 2-hydroxyalkanoates, n-alkyl-salicylates and n-alkanoyl-salicylates), or even amino acid ions (aspartate, arginate, glycocholate, fumarate).

In general, a composition of the device according to the invention contains at least one mixture of several electrolytes chosen from alkaline earth metal salts and in particular calcium salts, alkali metal salts and in particular salts of sodium and potassium, as well as magnesium and manganese salts and carbonates, bicarbonates, sulphates, phosphates, bromides, chlorides and fluorides.

It is also possible to use a natural mixture of electrolytes or a mixture whose composition is close to that of a natural mixture, and in particular commercial powder mixtures such as commercial products, bulk powders® powder and electrolytes from global medics ® to be diluted in demineralised water.

The electrolytes can be implemented as such or in the form of a solution generally of water or an aqueous medium containing them in the state of solutes such as for example sea water, thermal water or water mineral. In general, mineral water is suitable for consumption, which is not always the case with thermal water. Each of these waters contains, among other things, dissolved minerals and trace elements.

The nature of its salts and their respective amounts are of course adjusted to be physiologically acceptable. Thus, for example, in the case where sea water is considered as an electrolyte source, it is used in a form depleted in NaCl or even desalted.

Aqueous medium

A composition of the device according to the invention comprises at least 50% by weight and in particular at least 80% by weight of an aqueous medium relative to its total weight.

This aqueous medium is or contains water and preferably spring, thermal or mineral water.

It can also be partly formed from sea water, which as detailed above can be considered in a composition of the device according to the invention as a source of electrolytes.

The thermal water or the mineral water used can be chosen, for example, from Vittel water, water from the Vichy basin, Uriage water, water from Roche Posay, water from La Bourboule , water from Enghien-les-bains, water from Saint-Gervais-les-bains, water from Néris-les-bains, water from Allevard-les-bains, water from Digne, water from Maizières, water from Neyrac-les-bains, water from Lons le Saunier, Eaux Bonnes, water from Rochefort, water from Saint Christau, water from Fumades, water of Avène and the water of Tercis-les-bains.

According to one embodiment, a composition of the device according to the invention contains water and at least one mixture of several electrolytes chosen from alkaline-earth metal salts and in particular calcium salts, alkali metal salts and in particular sodium and potassium salts, as well as magnesium and manganese salts and carbonates, bicarbonates, sulphates, phosphates, bromides, chlorides and fluorides, in particular at a rate of 1 to 20%, preferably from 0.10 to 0, 5% of its total weight.

According to a particular variant of the invention, the composition of the device according to the invention contains:

- at least the oligopeptide fraction isolated from a lysate of a fermentation medium of a proteobacterium Vitreoscilla filiformis , in particular the strain Vitreoscilla filiformis ATCC 15551,

- at least one mucopolysaccharide, in particular at least one carrageenan,

- at least one moisturizing agent chosen from glycerol, aminoglycerol, urea, their salts and mixtures thereof,

- at least desalinated seawater and

- some water.

By way of non-limiting illustration of compositions of the device according to the invention, mention may in particular be made of aqueous care, hygiene and/or cleaning compositions containing:

- at least the oligopeptide fraction isolated from a lysate of a fermentation medium of a proteobacterium Vitreoscilla filiformis , in particular the strain Vitreoscilla filiformis ATCC 15551,

- approximately 0.05% by weight of at least one mucopolysaccharide, in particular at least one carrageenan, relative to its total weight,

- approximately 15% by weight of at least one moisturizing agent chosen from glycerol, aminoglycerol, urea, their salts and mixtures thereof relative to its total weight,

- approximately 10% by weight of desalinated seawater relative to its total weight and

- approximately 74% by weight of water, distinct from seawater, in relation to its total weight.

Surfactants

A composition of the device according to the invention may also contain one or more surfactants, in particular for their detergent properties.

This surfactant component is of course chosen on the one hand, for its compatibility with the other ingredients present in the composition and on the other hand so as not to harm the qualities sought for the claimed composition.

In particular, this surfactant component is chosen from biosurfactants.

Surfactants of lauryl sulphate type may also be suitable. However, when the compositions according to the invention are very particularly intended to be assimilated to so-called biosourced products, biosurfactants are preferred.

For the record, biosurfactants are surfactants of microbial origin. They are produced and excreted by several specific bacterial strains, in particular those of the genus Pseudomonas and Bacillus for example.

Several types of biosurfactants exist, including glycolipids (including rhamnolipids), and lipopeptides which are particularly suitable for the invention.

These biosurfactants have the advantage of being both effective as a surfactant and biodegradable and therefore advantageously non-persistent in the environment, one of the objectives pursued according to the present invention.

Such surfactants are described in particular in the article D.K De Santos et al. March 18, 2016 International Journal of Molecular Sciences.

By way of non-limiting illustration of surfactants suitable for the invention, mention may in particular be made of spiculisporic acid (S-acid) and its salts, in particular that marketed under the name S acid by the company Iwota Chemical, rhamnolipids in particular that marketed under the name Rhamnolipid L by the company Kaneka, the Sophorolipids, in particular that marketed under the name Sopholiance S by the company Solinace-Givaudan, and the surfactins in particular those marketed under the trade name Surfactin sodium salt by the company Evonik.

Additives

In a known manner, the care and cleansing compositions and therefore those according to the invention may contain, in addition to the compounds required according to the invention, one or more conventional adjuvants in the cosmetics field (perfume, fillers, odor absorbers, coloring materials …) and one or more cosmetic or therapeutic active agents different from the active agents required according to the invention.

More particularly, this or these other cosmetic or therapeutic active agents can be chosen from sunscreens; desquamating or exfoliating agents such as, for example, compounds derived from salicylic acid or their salts; depigmenting agents; pro-pigments; alpha-hydroxy acids; anti-bacterial agents; free radical scavengers; anti-pollution agents; retinoids; extracts, of fungi, of plants other than algae, of bacteria other than proteobacteria; hydrolyzed, partially hydrolyzed or non-hydrolyzed proteins; enzymes, hormones, yeast extracts, vitamins and their derivatives, flavonoids and isoflavones, and mixtures thereof.

They can in particular be chosen from enzymes, in particular proteases which are useful for the digestion of corneocytes, such as Papain from BASF or Patel from Papain Industries, beta-glucosidases such as those from almonds such as cellobiose marketed by Novozymes or beta glucosidase Aspergillus niger from Megazymes, subtilisin in particular such as those marketed by Novozyme, alcalase such as in particular collupilin marketed by DSM and bromelain from the company Enzybel.

The amounts of these various adjuvants are those conventionally used in the field considered, and for example can vary from 0.01 to 5% and preferably from 0.1 to 1% by weight of the total weight of the composition.

Galenic formulas

The compositions of the device according to the invention are suitable for external topical application. To do so, they are presented at the time of application in a liquid dosage form and in particular in the form of aqueous, hydroalcoholic solutions, solutions or dispersions of the lotion, gel or serum type, or even emulsions of liquid consistency. When the composition is an emulsion, the proportion of the fatty phase can range from 0.5% to 30% by weight, and preferably from 1% to 20% by weight relative to the total weight of the composition. The oils, waxes, emulsifiers or even co-emulsifiers used in the composition in emulsion form are chosen from those conventionally used in the cosmetics field.

The compositions of the device according to the invention can be used on the skin or the keratin fibers including the scalp, the hair, the eyelashes, the eyebrows, or the other keratin materials such as the nails, or the mucous membranes, in particular in the form a hygiene product, for example in the form of a cleaning product for the skin, mucous membranes and/or hair, beard, in particular in the form of a cleaning product and/or make-up removal for the skin (of the face and/or body), in the form of a shower product, in the form of a shampoo and conditioner, in the form of a shaving product, in the form of a rinse-off mask, in the form of an exfoliating product (also called desquamating or exfoliating agent) both for the face and for the body or for the hands, after addition of exfoliating particles.

The invention may be better understood on reading the detailed description which follows, non-limiting examples of implementation thereof, and on examining the appended drawing, in which:

there shows in schematic exploded view and in perspective an example of a device according to the invention,

there represents in front view, schematically, the device of the mounted with a first sole,

there schematically shows in side view the device of the ,

there represents in front view the device of the mounted with a second sole,

there schematically shows in side view the device of the ,

there represents in a schematic and isolated manner, in front view, the body of the device of the ,

there schematically represents in side view the body of the ,

there schematically represents in a bottom view the body of the ,

there is a longitudinal sectional and perspective view of the body of the device of the ,

there is a schematic partial longitudinal sectional view of the device of the , once mounted,

there represents in isolation, schematically and in perspective, the second sole of Figures 4 and 5,

there is a schematic view of the inside of the sole of the ,

there is a schematic side view according to XIII of the sole of the ,

there is another side view according to XIV schematic of the sole of the ,

there represents schematically and in perspective, in isolation, the first sole of Figures 2 and 3,

there schematically represents the inside of the sole of the ,

there schematically represents in side view according to XVII the sole of the ,

there schematically represents in another side view according to XVIII the sole of the ,

there schematically and isolated in longitudinal section shows the cap of the device of the ,

there represents, in perspective, in a schematic and partial manner, an example of a device according to the invention during its use,

there is a schematic enlarged view of detail XXI of the ,

there represents in isolation, schematically and in perspective, an example of a sole on the inside of the latter,

there represents, schematically in an exploded perspective front view, another example of a device according to the invention, without the sole,

there represents the device of the assembled, in schematic rear view and in perspective, with the sole,

there represents in isolation, schematically and in perspective, another example of a body that can form part of the device according to the invention,

there represents in isolation, schematically and in perspective, another example of a body that can form part of the device according to the invention,

there represents in isolation, schematically and in perspective, another example of a body that can form part of the device according to the invention, and

there schematically represents an example of a method of manufacturing the device according to the invention, and

there schematically represents the cleaning gesture protocol considered for testing the effectiveness of the device according to the invention.

detailed description

In the remainder of the description, identical elements or identical functions bear the same reference sign. For the purpose of conciseness of the present description, they are not described with regard to each of the figures, only the differences between the embodiments being described.

In the figures, the actual proportions have not always been respected, for the sake of clarity.

A first embodiment will be described in view of FIGS. 1 to 19. an example of a device 1 for cleaning the skin and/or keratin fibers such as the hair or the beard and/or the mucous membranes and/or the nails, according to the invention, comprising a body 2 intended to contain the composition such as previously defined. The body 2 comprises at least one wall 3 delimiting a volume forming a reservoir 4 to house the composition. At least part of the wall 3 is elastically deformable. The body 2 further comprises at least one supply orifice 5, in the example illustrated five through supply orifices 5, to allow the exit of the cleaning composition outside the body 2.

The device 1 further comprises at least one valve 6, in this example five valves 6 capable of closing or not, each, one of the supply orifices 5.

The device 1 further comprises at least one sole 10, in this example two soles 10, respectively 10a and 10b, intended to be in contact, with a view to cleaning, with the skin and/or the keratin fibres. In the example illustrated, the sole 10a is intended to be in contact with the skin while the sole 10b is intended to be in contact with the keratin fibres.

Each sole 10 is capable of being removably fixed to the body 2 and has an outer surface 15 comprising cleaning reliefs 7 comprising, in this example, studs 16.

In the example illustrated, at least one barb 16, referenced 16a, as seen more specifically in Figures 11 and 15, in this example five barbs 16a, has a passage 17 leading to a dispensing opening 18 for dispensing the composition cleaning. This pin 16a is positioned on the sole 10 such that when the sole 10 is fixed to the body 2, the supply orifice 5 is positioned relative to the pin 16a to allow the distribution of the cleaning composition from the reservoir 4 to at dispensing opening 18.

As can be seen on the and as will be described below, the studs 16 of the sole 10a are at least partly different from the studs 16 of the sole 10b.

Always on the , the presence in the device 1 of retaining elements 11 forming rings intended to allow cooperation between the valves 6 and the shutters 5 is visualized. Each retaining element 11 is thus arranged to make the valve 6 cooperate with an orifice of 5 matching power supply. Each retaining element 11 forms a ring of external diameter substantially equal to that of the supply orifice 5 and of internal diameter substantially equal to the external diameter of a part of the valve 6, so as to externally hold the valve 6 and to cooperate internally with the supply orifice 5. This arrangement is visible more particularly on the .

Each valve 6 is configured so as to allow retention of the cleaning composition in the absence of pressure exerted on the wall 3 in its elastically deformable part and the outlet of cleaning composition when pressure is exerted on the elastically deformable part of the wall 3. As seen on the and the , each valve 6 has in this example a base 21 of annular shape with one end 22 of the base having a larger diameter than the rest of the base. The valve 6 also has a shutter 20 fixed to the base 21, the shutter 20 comprising in this example two elastically deformable membranes cooperating in the absence of pressure so as to prevent any passage of the cleaning composition and defining between them an opening when a pressure is exerted on the elastically deformable part of the wall 3 of the body 2 to allow the passage of the cleaning composition. As seen on the , each supply orifice 5 comprises a first supply orifice portion 5a, on the side of the tank 4, and a second supply orifice portion 5b, of diameter greater than that of the first portion 5a, s' extending in the axial extension thereof. A shoulder 5c connects the first portion 5a to the second portion 5b. The second portion 5b houses the valve 6. The end 22 of the base 21 of the valve 6 comes into axial abutment against the shoulder 5c. The retaining element 11 inserted in the second portion 5b of the supply orifice itself comes into axial support against the end 22 and in transverse support against the rest of the base 21.

The device 1 also includes a plug 12, visible on the and in isolation on the , intended to cooperate with a filling opening 50, visible in Figures 8 and 9, to allow filling of the reservoir 4 with cleaning composition.

The body 2 is made entirely of an elastically deformable material in the example shown, in particular of high performance biosourced elastomer, that is to say obtained by a process from plant material, in this example consisting of a thermoplastic elastomer ( TPE) from the range of bioTPE marketed by the company NaturePlast, being made in one piece by injection molding of material. Similarly, the soles 10 are entirely made of at least one elastically deformable material, also of high performance biosourced elastomer in this example consisting of a thermoplastic elastomer from the range marketed under the name Dryflex® Green marketed by the company Hexpol, also made, each, in one piece by material injection molding.

Figures 2 and 3 show the device 1 assembled with the sole 10a mounted on the body 2. It can be seen in particular in this figure that, in this example, the sole 10a and the body 2 extend along a curved longitudinal axis X. Figures 4 and 5 show the device 1 assembled with the sole 10b mounted on the body 2. The sole 10b also extends along the curved longitudinal axis X. The soles 10a and 10b have substantially similar overall shapes and outer contour.

For the removable attachment of the sole 10a or the sole 10b to the body 2, as visible in Figures 16 and 12, respectively, the soles 10a and 10b comprise, on a lower surface 25 opposite the outer surface 15, a relief of fixing 26.

As for him, as visible in particular in Figures 1, 6, 7, 8 and 9, the body 2 has on a front part 27 a complementary fixing relief 28 able to cooperate, in this example mechanically, with the fixing relief 26 of the soles 10a and 10b for the removable fixing of these soles 10a and 10b, alternately, on the body 2.

In the example illustrated, the complementary fixing relief 28 forms a bead extending towards the outside of the body 2 and having a contour 35, substantially in the shape of a bean, which is closed around a zone 36. The contour 35 of the bead has a shape similar to that of the outer contour 29 of the soles 10.

In the example illustrated, tabs 31 are formed at the longitudinal ends of sole 10 to facilitate gripping of sole 10, in particular for its removal from body 2.

Figures 12 and 16 show the openings 32 formed in the sole 10b or 10a, respectively. These openings 32 are continued by the passage 17 made in the five pins 16a to allow the passage of the cleaning composition.

The passage 17 of each pin 16a, as seen in particular in Figures 11 and 15, leads to the dispensing opening 18 for dispensing the cleaning composition. In the example illustrated, the passage 17 passes through the spike 16a from one end 33 of the spike 16a connected to the outer surface 15 of the sole 10 to a free end 34 of the spike 16a. The free end 34 has the dispensing opening 18 for the exit of the cleaning composition.

The supply orifices 5 are arranged on the body 2 in this example, as can be seen in particular on the or 6, in a row 40 provided to extend substantially in the middle of the sole 10 when the latter is fixed to the body 2. In the example illustrated, the sole 10 extends along a curved longitudinal axis X. In this case, the row 40 is also substantially curved, along the X axis with a curvature similar to a curvature of the curved longitudinal axis X of the sole 10. The spikes 16a are arranged on the soles 10a and 10b also in one row 39, in an identical manner, as visible for example in Figures 2, 4, 11 and 15, to allow good correspondence between supply orifices 5 and passages 17.

As can be seen in FIGS. 11, 13 and 14, soleplate 10b intended for cleaning keratin fibers only comprises curved spikes 16, including spikes 16a, all of which are inclined. These pins 16 are in this example configured to imitate the taste buds of the tongue of a feline, in this example consisting of a cat. In this example, the studs 16 are curved while being oriented towards a single imaginary point located at a distance from the sole 10b. The studs 16 are regularly arranged on the sole 10b on the outer surface 15, in rows, being the outer surface 15 of the sole. The spikes 16 have similar lengths and similar diameters and shapes apart from the five spikes 16a arranged in a central row 39 on the sole 10b. The pins 16 arranged close to the contour 29 have a diameter smaller than that of the pins 16 arranged near the row 39. The pins may have a Shore hardness of between 60 and 100 Shore A, this hardness possibly being greater than the hardness of the taste buds of a cat. The length can be greater than that of the papillae of a cat by at least 20%, in particular by at least 40%, for example by 60%. Such a hardness and such a length can make it possible to comb or brush human hair and/or to massage the scalp, effectively.

As visible in Figures 15, 17 and 18, the sole 10a intended for cleaning the skin comprises studs 16 denoted 16b of a first shape and studs 16 denoted 16c of a second shape, independently of the studs 16a allowing the distribution of the cleaning composition. The pins 16b and pins 16c differ in this example by the diameter, the pins 16b being of greater diameter than the pins 16c. The pins 16c are close to this contour 29 while the pins 16b are closer to the pins 16a. All the studs 16 of the sole 10a are straight, form a point, having a substantially conical shape, and extend substantially orthogonally to the sole 10a, being arranged parallel to each other, in particular in the form of rows parallel to each other, curved to follow the outer contour 29 of the sole 10a, as visible in particular on the or 2.

The sole 10a is not entirely covered with studs 16, in this example. It comprises a region 45, located in an upper part of the sole 10a as visible on the , comprising cleaning reliefs 7 forming strips 46 arranged orthogonally to the outer surface 15. Thus, when cleaning the skin, a massage or rubbing can be performed on the skin while applying the cleansing composition using the spikes 16 then scraping can be carried out with the strips 46 in order to remove, for example, the cleansing composition and/or dead cells and other impurities.

As visible in particular in Figures 1, 6, 7 and 9, the body 2 extends in the example illustrated from a lower end 44 to an upper end 41 along the curved longitudinal axis X. The body 2 comprises a base portion 42 including the lower end 44 and an upper portion 43 comprising the upper end 41. The width of the base portion 42 is greater than the width of the portion in the upper portion 43 in this example, the width of the upper portion 43 decreasing in the example illustrated in the direction of the upper end 41.

Furthermore, the body 2 has, in addition to the front part 27 comprising the complementary fixing relief 28, a rear part 47, opposite the front part 27, defining an ergonomic gripping part. Reservoir 4 is thus delimited by wall 3 which also partly forms the gripping part of the device.

In this example, there is no separate handle.

It is not beyond the scope of the invention if a separate handle is provided in the body, in addition to the reservoir, in particular if the shape of the reservoir is not ergonomic. In this case, the body may comprise a handle forming a handle on the upper face of the reservoir, a handle in which one could engage the hand and thus press on the reservoir to release the cleaning composition instead of squeezing the reservoir in the absence of separate handle.

The body 2 has a filling opening 50 for the cleaning composition as seen in Figures 8 and 9. To close this filling opening 50, the plug 12 visible in isolation on the is planned. The cap 12 comprises an outer skirt 51 arranged to cover the wall 3 of the body 2 in the base portion 42 of the body 2. Furthermore, the cap 12 comprises internally in a central part a stud 52 intended to cooperate internally with a skirt 53 defining the filling opening 50, as seen in the , by snap-fastening or threading, so as to seal the filling opening 50 in a sealed manner. that the wall 3 is recessed in the lower part 54 to allow the outer skirt 51 of the cap 12 to be flush without extra thickness when the cap 12 is fixed to the body 2, as can be seen in Figures 2 to 5.

To use the device 1 according to the invention, the reservoir 4 is filled with the composition.

A sole 10 is secured to the body 2, for example the sole 10a for cleaning the skin using the complementary reliefs 26 and 28.

The elastically deformable rear part 47 of the body 2 is pressed so as to create an overpressure aimed at opening the shutters 20 of the valves 6 and allowing the cleaning composition to pass from the reservoir 4 to the dispensing openings 18 at the end of the pins 16a. The skin is rubbed, massaged, for example in a circular manner, in order to clean it. The strips 46 then make it possible to scrape the skin in order, for example, to remove all or part of the resulting cleansing composition and impurities and dead cells.

For cleaning the keratin fibres, the procedure is the same except that the sole 10b is secured in place of the sole 10a and the spikes 16 are brought into contact with the keratin fibers so as to apply a cleansing composition to the latter. and brushing, combing or massaging the scalp.

The invention makes it possible to effectively cleanse the skin or the keratin fibers using the device 1 provided according to the invention without requiring the addition of water or requiring little addition of water, which may prove useful in case of lack of water or for a person who is not or not very mobile.

As a variant, the tank can be filled with a flexible bottle surmounted by a cone which would fit into a hole made in the upper face of the tank, possibly formed in an elastomer skirt which opens when the bottle of cleaning composition and which closes when removed.

There is shown in Figures 20 to 22 another embodiment of the sole 10, in which the relief 26 comprises a rim 30 extending over the entire contour of the sole, in a uniform manner, as visible on the .

Furthermore, in this embodiment, the retaining elements 11 are made in one piece with the sole. The cleaning composition S can be seen in FIGS. 20 and 21 coming out at the end 34 of the pins 16a.

Figures 23 and 24 illustrate another embodiment of device 1 according to the invention. This device 1 differs from that illustrated in FIGS. 1 to 19 in that the body 2 comprises an air intake orifice 68, arranged in this example in the rear part 47 in the upper portion 43 of the body 2 as visible on the . Such an air intake orifice 68 is provided with a valve 69, in this example with a valve similar to the valve 6 which equips the supply orifices 5 for the composition outlet. In this case, the valve 69 is arranged to open when the user stops pressing on the body 2 so as to allow air to enter the reservoir 4. The body 2 can then regain its initial shape.

Furthermore, in the embodiment of Figures 23 and 24, the filling opening 50 is defined by the skirt 53 extending outside the reservoir 4, downwards.

An adapter piece 55 is interposed between the plug 12 and the body 2 so as to allow the plug 12 and the body 2 to cooperate with each other. The adaptation part 55 is mounted by force or by snap-fastening on the skirt 53 extending outside the tank 4. The adaptation part 55 itself comprises a skirt 56 extending substantially parallel to the skirt 53 of the body 2 and having an external thread capable of cooperating with a corresponding thread present on the central stud 52 of the plug 12 in order to be able to close the filling opening 50. As visible on the , the adapter piece 55 is provided to be flush with the surface of the body 2, like the cap 12.

There is shown in Figures 25 to 27 three other body shapes 2 possible.

On the , the rear part 47 forming the gripping part substantially reproduces the relief of the hand and the fingers.

There illustrates a body 2 of generally rounded shape in its rear part 47, with a hollow.

Finally, the illustrates a body 2 forming an elbow towards the rear part 47.

On the , various steps of an exemplary method of manufacturing a body 2 for a device 1 according to the invention have been shown.

The first step 60 consists in taking an image, in this example to be scanned, using a device O a hand M of a user. In a second step 61, the images resulting from the first step 60 are processed, so as to define an adequate profile of the wall 3 of the body 2. In a third step 62, the body 2 is produced by additive manufacturing of polymer material. One thus obtains, in a fourth step 63, the desired body 2, adapted to the user.

It should be noted that in this process as well as for the examples of figures 26 to 28, the front part 27 and the complementary relief 28 always remain identical and are not adapted, so that the body 2, whatever its shape, can be assembled with any sole 10.

Of course, the invention is not limited to the examples which have just been described.

In particular, the shape of the body 2 can be modified without departing from the scope of the invention.

The fixing reliefs 26 and complementary 28 can be different from those which have been described above while allowing them to cooperate with each other for the removable fixing of the sole 10 on the body 2, without departing from the scope of the invention.

The cleaning reliefs 7 may not include studs 16. The dispensing opening 18 may not be formed in a stud 16 but be present on the outer surface 15 of the sole 10 or be formed in a cleaning relief 7 other just a peck. In this case, the dispensing opening 18 is nevertheless provided to be positioned on the soleplate 10 so as to allow the cleaning composition to come out from the reservoir 4 as far as the dispensing opening 18 passing through the orifice of food 5.

The diameter of a barb 16 can be between 0.5 mm and 3 mm, being preferably around approximately 1 mm.

In a variant, the presence of the sole is necessary to unlock the valves and allow them to open under the pressure of the cleaning composition.

In another variant, the sole constrains the opening of the valves, so that depending on the sole placed on the body, the valves can open more or less.

In a particular embodiment, the device 1 does not include a valve 6.

In one embodiment, the sole is non-removably attached to the body.

In a variant, the body does not include an elastically deformable wall.

Materials and methods

A first test aims to evaluate the cleaning power of the device according to the invention on dirt formed from a mixture of charcoal and sebum particles, detailed below and which is deposited on a skin model: 7.6 μl/ cm² of a mixture of avocado oil (from Expanscience, virgin oil) (oily skin) + charcoal (Sigma Aldrich, activated charcoal) at 2% by weight of the mixture (dirty skin) is applied with a pipette to piston with inclination of the skin to distribute the solution evenly at ambient temperature and ambient humidity. The evaluation is made on a rectangular area of 10 cm by 4 cm. To do this, the synthetic skin is cut or an area of this size is defined on the forearm.

A second test aims to evaluate its cleansing power with respect to a foundation (L'Oréal Paris, Accord Parfait) which is applied to a tester's forearm to form a layer of foundation having a length and a respective width of 10 cm and 4 cm. The deposit of this foundation is formed by pressing three times on the dose, equivalent to 1.5 g, using three fingers to distribute the foundation evenly at ambient temperature and humidity.

Skin Models :

Sample of smooth synthetic skin (punch diameter 5cm) from Biolax: Bioskin Plate K520 thickness 2mm fixed with double-sided tape on a cork plate covered with aluminum foil.

Human skin forearm inner side of a tester.

n Protocol cleaning

It is done in 5 minutes after application of the composition to be cleaned.

100ml of the washing solution to be tested are integrated into the reservoir of the device 1 according to the invention as illustrated in the .

The washing solution is dispensed through the dispensing opening 18 formed in the pins 16a of the device 1, brought into contact with the skin to be cleaned and a recovery/rubbing gesture is applied with the sole 10 in the form of 9 passages, 3 zigzags to the left, 3 zigzags to the right with pins 16 then 3 straight passes with slats 46 according to the protocol shown schematically in figure 29.

The effectiveness of the cleaning is assessed by visual observation of the condition of the skin.

This effectiveness is characterized on a performance scale ranging from 5+ to 1+ (5+: the condition of the skin observed is clean and perfectly clean; 1+: the condition of the skin is not clean and we observe still some dirt).

The quantity of dirt (first test) or foundation (second test) recovered during the cleaning operation is determined by subtracting the mass of the device with the washing solution before cleaning, from its mass obtained after cleaning. It is then expressed as a percentage relative to the quantity of dirt or foundation deposited before cleaning.

Film-forming quality of the composition

The expert scores on a scale ranging from 5+ to 5- (5-: no perceived film-forming effect, rough skin; 5+: significant film-forming effect). Scoring is carried out 3 minutes after application of the product.

Determination of sensory feeling

The expert notes on a scale ranging from 5+ to 5- (5-: no perceived sensory effect; 5+: significant sensory effect) the intensity of the sensation perceived after application of the product. Scoring is carried out 3 minutes after application of the product.

Example 1

Preparation of a fraction oligopeptide isolated from a lysate of v. filiformis

The composition of the complete nutrient medium for the culture of V. filiformis is detailed in Table 1.

[Table 1]: Chemical name [ focus ] Autolytic yeast extract 4g/l Soy Papain Peptone F 3g/l Glucose – Roferosis 3g/l KH ₂ PO ₄ 0.088g/l _CaCl2 0.050g/l CuSO _4.5 H ₂ O 60 mcg/l MnSO ₄ , 1H ₂ O 152 mcg/l KI 20 µg/l ZnSO ₄ .7H ₂ O 200 mcg/l AlCl ₃ .6H ₂ O 100 µg/l Osmotic water qs 1 l

To obtain the oligopeptide fraction, the procedure is as described below.

The initial strain of V. filiformis is obtained from the ATCC (strain 15551).

The biomass is obtained by fermentation in an industrial bioreactor of 3000 efficient liters, the composition of the culture medium is given above. During the culture, the pH is kept constant (7.00), as well as the temperature (26°C) and the dissolved oxygen (0.5%). The culture is stopped when the dry matter content reaches 0.6% and the glucose content reaches 0.035%. The fermentation of the V. filiformis strain is carried out in its complete culture medium.

The whole is centrifuged and the pellet is treated by enzymatic digestion.

For enzymatic digestion is first introduced a carbohydrase Viscozyme® marketed by Novozyme in an amount of 0.2% w / w for a period of 3 hours at a temperature of 55 ° C the pH is adjusted and maintained at 4.5 by acid citric acid, then a Sumizyme AP protease marketed by Novozyme is introduced in an amount of 0.04% w/w for a period of 3 h at a temperature of 55° C. the pH is maintained at 4.5 after adjustment by adding citric acid if necessary and.

Following this second enzymatic digestion, the medium is neutralized to pH 7 using a sodium hydroxide solution (NaOH). The enzyme is inactivated by heating the medium to a temperature of 90°C for 15 minutes.

The neutralized and inactivated medium is clarified by successive filtrations first with a 10 μm pocket filter then a K2 filter.

An atomization step of the complete clarified reaction medium is carried out with a BUCHI mini spray dryer B-290 atomizer with the following parameters Pump 30%; INLET temperature 160°C; OUTLET temperature 85°C; Vacuum cleaner 95; Q flow 35. The oligopeptide fraction is then recovered in powder form and is used as it is in the examples which follow.

Example 2

Preparation of a composition of a device in accordance with the invention

A formula A is prepared by simple mixing under a vortex at room temperature, i.e. varying from 18°C to 25°C, of the 3 ingredients detailed in Table 2.

Ingredients Quantity
( g ) Glycerol 300 Millipore distilled water (miliQ system) 500 NaCl-free sea water
(filtered seawater, or holoslife or solnatural seawater) 200

A formula B is prepared by heating the water to 70°C and incorporating the two other ingredients detailed in Table 2, with stirring, until they dissolve.

Ingredients Quantity
( g ) carrageenan
(Cargill's Satiagel) 1 Example 1 Oligopeptide Fraction 3 Millipore distilled water (miliQ system) 1000

The two formulas are then mixed to form the expected composition.

Example 3

Preparation of compositions suitable for the device according to the invention.

Compositions 2a to 2f detailed below in Table 4 were prepared according to the protocol detailed in Example 2.

Compounds Examples
( in g) 2a 2b 2c 2d 2nd 2 F Glycerol 150 150 150 150 150 150 Caragheenane
(Cargill's Satiagel) 0.5 0.5 0.5 0.5 0.5 0.5 Example 1 Oligopeptide Fraction 1.5 1.5 1.5 1.5 1.5 1.5 papaine
(marketed by BASF) 0.1 Yeast extract
(marketed by Solabia) 0.1 Rhamnolipid
(marketed by Evonik) 0.1 Lysine salt of 2-hydroxy-6-pentadecylbenzoic acid
(as detailed in WO201666811) 0.1 Canarium Luzonicum Nonvolatile Gum
(Elemi resin from Firmenich)
0.1 NaCl-free sea water 100 100 100 100 100 100 Millipore distilled water (miliQ system) 750 750 750 750 750 750 pH 6.5 6.8 6.5 6.4 6.6 6.6

Example 4
Testing the cleaning effectiveness of a composition with the device according to the invention

A first test is carried out for enjoy the efficiency of 'A device according to the invention for the elimination of polluting particles and of A excess of sebum on a skin model synthetic and on the skin of a forearm .

To do this, the composition 2a of the example is introduced at a rate of 2 ml into the reservoir of the device 1 according to the invention and distributed on the skin according to the protocol detailed above and illustrated in .

For comparison, a control micellar solution, namely Créaline H20 Bioderma solution, is applied using a Demakup cotton ball, by depositing 2ml of micellar water on the skin then passing the cotton ball (Control A). Only three scrapings are made with the cotton.

To assess the effectiveness of the cooperation between a composition and a device 1 according to the invention, the following control tests B and C are also carried out:

Control B: composition 2a is used with the device according to the invention but in a dissociated manner, i.e. 2 ml of the composition are applied to the skin, followed by the implementation of the device. After application of the composition to the skin, only three scrapings are carried out with the spiked part of the device.

Control C: 2 ml of the micellar solution of control A are used with the device (excluding composition) according to the invention but in a dissociated manner, i.e. 2 ml of the solution are applied to the skin, followed by the implementation of the device. After application of the solution to the skin, only three scrapings are carried out with the spiked part of the device.

Control D: 2 ml of the micellar solution of control A are introduced into the reservoir of the device 1 according to the invention and distributed on the skin according to the protocol detailed above and illustrated in .

Results on synthetic skin

Cleaning with composition 2a applied with the device according to the invention on synthetic skin is visually better than when composition 2a is applied separately from the device (Control B), and much better visually than Controls A, C and D implementing the micellar solution.

Table 5 below shows the results obtained on the skin of a forearm.

Effect Composition 2a
applied according to the invention Witness A
Micellar solution then cotton Witness B
Composition 2a not applied according to the invention Witness C
Micellar solution not applied according to the invention Witness D:
Micellar solution applied according to the invention Efficacy of cleaning the dirt appreciated on the level of the cleansed skin +++++ + +++ + ++ Touched sensory feeling +++++
Pleasantly soft touch +
Acceptable touchdown ++ -
Bold touch -
Bold touch

Cleaning with composition 2a applied with the device according to the invention on human skin of a forearm is visually better than when composition 2a is applied separately from the device (Control B), and much better visually than the Controls A, C and D implementing the micellar solution.

Furthermore, it emerges from these results that the best performance is obtained when a cleansing composition in accordance with the invention is applied using a device according to the invention on the surface of the area of skin to be cleaned. The composition and device work well together to provide effective cleaning.

A second test is carried out to assess efficiency d ' A device according to the invention for the elimination of foundation applied to a zone of forearm skin .

The composition of example 2a is introduced into the reservoir of the device 1 according to the invention and distributed on the skin of a forearm according to the protocol detailed above and illustrated in .

The Sensibio H20 Bioderma micellar solution is tested in parallel as a control cleansing solution under the same application conditions. (Witness A)

To assess the effectiveness of the cooperation between a composition and a device 1 according to the invention, the following control tests B and C are also carried out.

Control B: the composition according to the invention is used with the device according to the invention but in a dissociated manner, i.e. 2 ml of the composition are applied to the skin, followed by the implementation of the device.

Control C: the micellar solution of control A is used with device 1 according to the invention but in a dissociated manner, i.e. 2 ml of the solution are applied to the skin, followed by the implementation of the device.

Table 6 below shows the results obtained.

Quality tested Composition 2a applied according to the invention Witness A
Control composition applied according to the invention Witness B
Composition 2a not applied according to the invention Witness C
Control composition not applied according to the invention Effectiveness of cleansing the foundation, assessed at the level of the cleansed skin.
+++++
+
+++
++ Proportion of foundation recovered during the cleaning operation.
90%
40%

65%
50%
Filmogenic feeling
+++++
-
++
- Sensory felt +++++ - ++ -

It emerges from these results that the best performance is obtained when a cleansing composition in accordance with the invention is applied using a device 1 according to the invention on the surface of the area of skin to be cleaned. The composition and device work well together to provide effective cleaning.

Claims (15)

Device (1) for packaging and dispensing a composition for cleaning the skin and/or keratin fibers and/or the mucous membranes and/or the nails, comprising:
- a composition, in particular cosmetic and non-therapeutic, for the care, hygiene and / or cleaning of the skin and / or keratin fibers and / or mucous membranes and / or nails, in the form of an aqueous solution including at least:
(i) all or part of a lysate, isolated or not from a fermentation medium of a non-pathogenic and aerobic proteobacterium or a (glyco)oligopeptide fraction isolated from such a lysate,
(ii) at least one mucopolysaccharide, in particular weighing more than 10kD,
(iii) at least one hydrating agent distinct from (i) and (ii) and chosen in particular from glycerol, aminoglycerol, urea, their salts and their mixtures,
(iv) at least one electrolyte,
(v) water and
(vi) where applicable, at least one cosmetic active ingredient distinct from (i), (ii) and (iii),
- a body (2) forming a reservoir (4) to contain the composition, the body (2) comprising at least one supply orifice (5) to allow the composition to exit from said body (2),
- at least one sole (10; 10a, 10b) intended to be in contact with the skin and/or the keratin fibers and/or the mucous membranes and/or the nails, fixed to the body (2) and having an outer surface (15 ) on which are provided cleaning reliefs (7) and at least one dispensing opening (18), the dispensing opening (18) and the said at least one supply orifice (5) being arranged so as to allow the distribution of composition. Device (1) according to claim 1, in which the cleaning reliefs (7) are configured to allow massaging, rubbing, brushing of the skin and/or keratin fibers and/or mucous membranes and/or nails with the sole (10; 10a, 10b). Device (1) according to Claim 1 or 2, in which all or part of the cleaning reliefs (7) comprise spikes (16). Device (1) according to claim 3, in which at least a part of the pins (16) is configured to imitate the papillae of the tongue of a feline, in particular of a cat. Device (1) according to any one of Claims 1 to 4, in which the cleaning reliefs (7) comprise at least one blade (46), in particular a plurality of blades, extending in particular substantially orthogonally from the outer surface (15) of the sole (10; 10a, 10b). Device (1) according to any one of the preceding claims, in which the sole (10; 10a, 10b) is removably fixed to the body (2). Device (1) according to any one of the preceding claims, in which the composition contains all or a fraction of lysate isolated from its fermentation medium. Device (1) according to any one of claims 1 to 6, wherein the composition contains said whole lysate in a complete fermentation medium. A device (1) according to any preceding claim, wherein said bacterium of the composition is a Vitreoscilla filiformis strain. A device (1) according to any preceding claim, wherein said bacterium of the composition is strain Vitreoscilla filiformis (ATCC 15551). Device (1) according to any one of the preceding claims, in which the composition contains at least one mucopolysaccharide extracted from seaweed, in particular chosen from carrageenans, alginates, ulvans, fucoidanes, chitosan, chitin, their salts, their extracts and their mixtures and in particular containing at least one carrageenan in particular derived from Chondrus crispus or Kappaphycus alvarezii. Device (1) according to any one of the preceding claims, in which the composition contains a mixture of several electrolytes chosen from alkaline earth metal salts and in particular calcium salts, alkali metal salts and in particular salts sodium and potassium, as well as magnesium and manganese salts and carbonates, bicarbonates, sulphates, phosphates, bromides, chlorides and fluorides. Device (1) according to any one of the preceding claims, in which the composition comprises at least 50% by weight and in particular at least 80% by weight of an aqueous medium relative to its total weight. Device (1) according to any one of the preceding claims, in which the composition contains at least
- at least the oligopeptide fraction isolated from a lysate of a fermentation medium of a proteobacteriumVitreoscilla filiformis, in particular the strainVitreoscilla filiformisATCC 15551,
- approximately 0.05% by weight of at least one mucopolysaccharide, in particular at least one carrageenan, relative to its total weight,
- approximately 15% by weight of at least one moisturizing agent chosen from glycerol, aminoglycerol, urea, their salts and mixtures thereof relative to its total weight,
- about 10% by weight of desalinated seawater compared to its total weight And
- approximately 74% by weight of water, distinct from seawater, in relation to its total weight. Method for cleaning the skin and/or keratin fibers and/or mucous membranes and/or nails using a device (1) according to any one of the preceding claims, the method comprising the following steps:

1. Step a: cause the composition to be dispensed through said at least one dispensing opening (18),
2. Step b: bringing the dispensed composition and the cleansing reliefs (7) into contact with the skin and/or the keratin fibers and/or the mucous membranes and/or the nails,
3. Step c: rub, massage, brush and/or comb the skin and/or the keratin fibers and/or the mucous membranes and/or the nails using the cleansing reliefs (7).