FR3112390B1 - Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid - Google Patents

Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid Download PDF

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Publication number
FR3112390B1
FR3112390B1 FR2007201A FR2007201A FR3112390B1 FR 3112390 B1 FR3112390 B1 FR 3112390B1 FR 2007201 A FR2007201 A FR 2007201A FR 2007201 A FR2007201 A FR 2007201A FR 3112390 B1 FR3112390 B1 FR 3112390B1
Authority
FR
France
Prior art keywords
light
hemoglobin
level
hematocrit level
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2007201A
Other languages
French (fr)
Other versions
FR3112390A1 (en
Inventor
Stéphane Chollet
Gaëtan Coulon
Benoît Decouture
Sylvain Picot
Patricia Forest-Villegas
Francis Gadrat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I Sep SAS
Original Assignee
I Sep SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR2007201A priority Critical patent/FR3112390B1/en
Application filed by I Sep SAS filed Critical I Sep SAS
Priority to PCT/FR2021/051272 priority patent/WO2022008850A1/en
Priority to EP21746535.0A priority patent/EP4179318B1/en
Priority to AU2021306678A priority patent/AU2021306678A1/en
Priority to US18/004,547 priority patent/US20230347036A1/en
Priority to CN202180061668.5A priority patent/CN116249893A/en
Priority to CA3184950A priority patent/CA3184950A1/en
Priority to EP21746534.3A priority patent/EP4178442A1/en
Priority to PCT/FR2021/051271 priority patent/WO2022008849A1/en
Priority to BR112023000088A priority patent/BR112023000088A2/en
Priority to US18/004,399 priority patent/US20230280331A1/en
Priority to BR112023000158A priority patent/BR112023000158A2/en
Priority to CN202180050925.5A priority patent/CN116324384A/en
Publication of FR3112390A1 publication Critical patent/FR3112390A1/en
Application granted granted Critical
Publication of FR3112390B1 publication Critical patent/FR3112390B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N21/3151—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using two sources of radiation of different wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/207—Blood composition characteristics hematocrit

Abstract

Abrégé descriptif : L’invention concerne un appareil et un procédé de détermination du taux d’hématocrite et/ou du taux d’hémoglobine d’un liquide en circulation dans une portion tubulaire (2), le procédé comprenant : - l’émission de faisceaux lumineux en direction de la portion tubulaire (2) avec au moins deux sources lumineuses (11 ; 21), chacune des deux sources lumineuses (11 ; 21) étant configurée pour émettre des faisceaux lumineux selon une longueur d’onde d’émission choisie pour correspondre à un point isobestique de l’hémoglobine ; - la réception de signaux lumineux transmis à travers la portion tubulaire (2) avec au moins deux capteurs lumineux (12 ; 22), chaque capteur lumineux (12 ; 22) étant associé à l’une des deux sources lumineuses (11 ; 21) ; - calcul du taux d’hématocrite et/ou du taux d’hémoglobine du liquide par un traitement des signaux lumineux reçus par les capteurs lumineux (12 ; 22) ;caractérisé en ce que la puissance d’émission d’au moins une des sources lumineuses (11 ; 21) est modifiée au cours de la détermination du taux d’hématocrite et/ou du taux d’hémoglobine en fonction du taux d’hématocrite et/ou respectivement du taux d’hémoglobine calculé pour le liquide. Figure de référence : figure 1The invention relates to an apparatus and a method for determining the hematocrit level and/or the hemoglobin level of a liquid circulating in a tubular portion (2), the method comprising: - the emission of light beams in the direction of the tubular portion (2) with at least two light sources (11; 21), each of the two light sources (11; 21) being configured to emit light beams according to a chosen emission wavelength to correspond to an isosbestic point of hemoglobin; - the reception of light signals transmitted through the tubular portion (2) with at least two light sensors (12; 22), each light sensor (12; 22) being associated with one of the two light sources (11; 21) ; - calculation of the hematocrit level and/or the hemoglobin level of the liquid by processing the light signals received by the light sensors (12; 22);characterized in that the emission power of at least one of the sources lights (11; 21) is changed during the determination of the hematocrit level and/or the hemoglobin level depending on the hematocrit level and/or respectively the hemoglobin level calculated for the liquid. Reference Figure: Figure 1

FR2007201A 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid Active FR3112390B1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR2007201A FR3112390B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid
US18/004,399 US20230280331A1 (en) 2020-07-08 2021-07-08 Device And Method For Determining The Haemoglobin Or Haematocrit Level Of A Flowing Liquid
AU2021306678A AU2021306678A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
US18/004,547 US20230347036A1 (en) 2020-07-08 2021-07-08 Device For Determining The Level Of Haemoglobin Or Haematocrit Of A Circulating Liquid
CN202180061668.5A CN116249893A (en) 2020-07-08 2021-07-08 Device for determining the hemoglobin level or hematocrit level of a circulating liquid
CA3184950A CA3184950A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
PCT/FR2021/051272 WO2022008850A1 (en) 2020-07-08 2021-07-08 Device and method for determining the haemoglobin or haematocrit level of a flowing liquid
PCT/FR2021/051271 WO2022008849A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
BR112023000088A BR112023000088A2 (en) 2020-07-08 2021-07-08 APPARATUS FOR DETERMINING THE HEMOGLOBIN OR HEMATOCRIT RATE OF A FLUID IN CIRCULATION
EP21746535.0A EP4179318B1 (en) 2020-07-08 2021-07-08 Device and method for determining the haemoglobin or haematocrit level of a flowing liquid
BR112023000158A BR112023000158A2 (en) 2020-07-08 2021-07-08 APPARATUS AND PROCESS FOR DETERMINING THE HEMOGLOBIN OR HEMATOCRIT RATE OF A FLUID IN CIRCULATION
CN202180050925.5A CN116324384A (en) 2020-07-08 2021-07-08 Device and method for determining the hemoglobin or hematocrit level of a flowing liquid
EP21746534.3A EP4178442A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2007201A FR3112390B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid
FR2007201 2020-07-08

Publications (2)

Publication Number Publication Date
FR3112390A1 FR3112390A1 (en) 2022-01-14
FR3112390B1 true FR3112390B1 (en) 2022-06-24

Family

ID=73642997

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2007201A Active FR3112390B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating fluid

Country Status (1)

Country Link
FR (1) FR3112390B1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2824033A1 (en) * 2005-09-13 2007-03-22 Edwards Lifesciences Corporation Continuous spectroscopic measurement of total hemoglobin
WO2008136548A1 (en) * 2007-05-07 2008-11-13 Jsm Healthcare Inc Device of measuring and monitoring a hemoglobin value through blood tube
JP6059150B2 (en) * 2010-11-17 2017-01-11 フレセニウス メディカル ケア ホールディングス インコーポレーテッド Sensor clip assembly for optical monitoring systems

Also Published As

Publication number Publication date
FR3112390A1 (en) 2022-01-14

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