FR3095646B1 - Methode de production de peptides ou proteines ou peptidomimetiques - Google Patents

Methode de production de peptides ou proteines ou peptidomimetiques Download PDF

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Publication number
FR3095646B1
FR3095646B1 FR1904604A FR1904604A FR3095646B1 FR 3095646 B1 FR3095646 B1 FR 3095646B1 FR 1904604 A FR1904604 A FR 1904604A FR 1904604 A FR1904604 A FR 1904604A FR 3095646 B1 FR3095646 B1 FR 3095646B1
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FR
France
Prior art keywords
peptidomimetics
proteins
peptide
protein
natural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1904604A
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English (en)
Other versions
FR3095646A1 (fr
Inventor
Tendoung Jean-Jacques Youte
Audrey Serre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Strainchem
Original Assignee
Strainchem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1904604A priority Critical patent/FR3095646B1/fr
Application filed by Strainchem filed Critical Strainchem
Priority to JP2021564322A priority patent/JP7459435B2/ja
Priority to BR112021021524A priority patent/BR112021021524A2/pt
Priority to PCT/FR2020/000158 priority patent/WO2020221970A1/fr
Priority to SG11202111716TA priority patent/SG11202111716TA/en
Priority to US17/605,008 priority patent/US20230219999A1/en
Priority to CA3134570A priority patent/CA3134570A1/fr
Priority to CN202080033092.7A priority patent/CN114008066A/zh
Priority to AU2020266294A priority patent/AU2020266294B2/en
Priority to EP20730450.2A priority patent/EP3962922A1/fr
Publication of FR3095646A1 publication Critical patent/FR3095646A1/fr
Priority to IL287411A priority patent/IL287411A/en
Priority to ZA2021/09853A priority patent/ZA202109853B/en
Application granted granted Critical
Publication of FR3095646B1 publication Critical patent/FR3095646B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procédé de synthèse de peptides ou protéines ou peptidomimétiques par élongation successive de la deuxième extrémité (fonction amine primaire ou secondaire, hydroxyle ou thiol) d’une chaîne peptidique ou protéique ou peptidomimétique par des unités, caractérisé en ce que : lesdites unités sont sélectionnées dans le groupe formé par : les acides α, β ou γ-aminés, les acides α, β ou γ-hydroxylés, les α, β ou γ-mercapto acides (naturels ou non naturels ou synthétiques), les molécules ayant au moins deux groupements fonctionnels ; la première extrémité dudit peptide ou protéine ou peptidomimétique est fixée par une liaison covalente à une molécule d’ancrage soluble dans des solvants organiques tels que les solvants halogénés (chlorure de méthylène, chloroforme), l’acétate d’éthyle, le tétrahydrofurane, le 2-méthyletétrahydrofurane, l’isooctane, le cyclohexane, l’hexane(s), le méthylcyclohexane, le méthyl tert-butyl éther ou des solvants aromatiques tels que le benzène ou le toluène ou tout autre solvant adéquat.
FR1904604A 2019-05-02 2019-05-02 Methode de production de peptides ou proteines ou peptidomimetiques Active FR3095646B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR1904604A FR3095646B1 (fr) 2019-05-02 2019-05-02 Methode de production de peptides ou proteines ou peptidomimetiques
AU2020266294A AU2020266294B2 (en) 2019-05-02 2020-05-04 Method for producing peptides or proteins or peptidomimetics
PCT/FR2020/000158 WO2020221970A1 (fr) 2019-05-02 2020-05-04 Methode de production de peptides ou proteines ou peptidomimetiques
SG11202111716TA SG11202111716TA (en) 2019-05-02 2020-05-04 Method for producing peptides or proteins or peptidomimetics
US17/605,008 US20230219999A1 (en) 2019-05-02 2020-05-04 Method for producing peptides or proteins or peptidomimetics
CA3134570A CA3134570A1 (fr) 2019-05-02 2020-05-04 Methode de production de peptides ou proteines ou peptidomimetiques
JP2021564322A JP7459435B2 (ja) 2019-05-02 2020-05-04 ペプチド又はタンパク質又はペプチド模倣体の製造方法
BR112021021524A BR112021021524A2 (pt) 2019-05-02 2020-05-04 Método para a produção de peptídeos ou proteínas ou peptidomiméticos
EP20730450.2A EP3962922A1 (fr) 2019-05-02 2020-05-04 Methode de production de peptides ou proteines ou peptidomimetiques
CN202080033092.7A CN114008066A (zh) 2019-05-02 2020-05-04 肽或蛋白质或拟肽的制造方法
IL287411A IL287411A (en) 2019-05-02 2021-10-19 A method for the production of peptides or proteins or peptidomimetic compounds
ZA2021/09853A ZA202109853B (en) 2019-05-02 2021-12-01 Method for producing peptides or proteins or peptidomimetics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1904604 2019-05-02
FR1904604A FR3095646B1 (fr) 2019-05-02 2019-05-02 Methode de production de peptides ou proteines ou peptidomimetiques

Publications (2)

Publication Number Publication Date
FR3095646A1 FR3095646A1 (fr) 2020-11-06
FR3095646B1 true FR3095646B1 (fr) 2024-02-23

Family

ID=68424951

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1904604A Active FR3095646B1 (fr) 2019-05-02 2019-05-02 Methode de production de peptides ou proteines ou peptidomimetiques

Country Status (12)

Country Link
US (1) US20230219999A1 (fr)
EP (1) EP3962922A1 (fr)
JP (1) JP7459435B2 (fr)
CN (1) CN114008066A (fr)
AU (1) AU2020266294B2 (fr)
BR (1) BR112021021524A2 (fr)
CA (1) CA3134570A1 (fr)
FR (1) FR3095646B1 (fr)
IL (1) IL287411A (fr)
SG (1) SG11202111716TA (fr)
WO (1) WO2020221970A1 (fr)
ZA (1) ZA202109853B (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451915A1 (fr) 1979-03-23 1980-10-17 Clin Midy Nouveau procede de preparation de la somatostatine
NL1010867C2 (nl) 1998-12-22 2000-06-23 Dsm Nv Werkwijze voor de bereiding van aminozuuramiden of derivaten daarvan.
DK2612845T3 (da) * 2010-08-30 2020-11-02 Ajinomoto Kk Aromatisk forbindelse som indeholder specifik forgrening
WO2013089241A1 (fr) 2011-12-15 2013-06-20 味の素株式会社 PROCÉDÉ D'ÉLIMINATION D'UN GROUPE Fmoc

Also Published As

Publication number Publication date
ZA202109853B (en) 2023-10-25
WO2020221970A1 (fr) 2020-11-05
FR3095646A1 (fr) 2020-11-06
AU2020266294A1 (en) 2021-11-25
IL287411A (en) 2021-12-01
JP7459435B2 (ja) 2024-04-02
JP2022531195A (ja) 2022-07-06
CN114008066A (zh) 2022-02-01
US20230219999A1 (en) 2023-07-13
CA3134570A1 (fr) 2020-11-05
SG11202111716TA (en) 2021-11-29
EP3962922A1 (fr) 2022-03-09
AU2020266294B2 (en) 2024-05-30
BR112021021524A2 (pt) 2022-01-04

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