FR3018357B1 - Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques - Google Patents

Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques Download PDF

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Publication number
FR3018357B1
FR3018357B1 FR1451740A FR1451740A FR3018357B1 FR 3018357 B1 FR3018357 B1 FR 3018357B1 FR 1451740 A FR1451740 A FR 1451740A FR 1451740 A FR1451740 A FR 1451740A FR 3018357 B1 FR3018357 B1 FR 3018357B1
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FR
France
Prior art keywords
lectines
applications
detection
new
modules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1451740A
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English (en)
Other versions
FR3018357A1 (fr
Inventor
Anne Imberty
Aymeric AUDFRAY
Julie ARNAUD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Joseph Fourier Grenoble 1 filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1451740A priority Critical patent/FR3018357B1/fr
Priority to US15/123,138 priority patent/US10247734B2/en
Priority to PCT/IB2015/051422 priority patent/WO2015132699A1/fr
Priority to EP15711300.2A priority patent/EP3114487A1/fr
Publication of FR3018357A1 publication Critical patent/FR3018357A1/fr
Application granted granted Critical
Publication of FR3018357B1 publication Critical patent/FR3018357B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4724—Lectins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Lectines multimériques avec une architecture de type β-propeller, formées de modules monomères d'environ de 30 à 60 acides aminés, dans lesquels les sites de fixation aux glycanes sont situés d'un même côté des protéines et les extrémités C-ter et N-ter des chaînes peptidiques de l'autre côté des protéines, caractérisées en ce qu'elles sont formées de 4 à 7 modules monomères, un seul, ou plusieurs ou la totalité des modules adjacents étant reliés entre eux par des linkers liant l'extrémité N-terminale d'un module à l'extrémité C-terminale du module adjacent.
FR1451740A 2014-03-04 2014-03-04 Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques Expired - Fee Related FR3018357B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR1451740A FR3018357B1 (fr) 2014-03-04 2014-03-04 Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques
US15/123,138 US10247734B2 (en) 2014-03-04 2015-02-26 Lectins and applications for the detection of pathological state markers
PCT/IB2015/051422 WO2015132699A1 (fr) 2014-03-04 2015-02-26 Nouvelles lectines et applications pour la détection de marqueurs d'états pathologiques
EP15711300.2A EP3114487A1 (fr) 2014-03-04 2015-02-26 Nouvelles lectines et applications pour la détection de marqueurs d'états pathologiques

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1451740A FR3018357B1 (fr) 2014-03-04 2014-03-04 Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques
FR1451740 2014-03-04

Publications (2)

Publication Number Publication Date
FR3018357A1 FR3018357A1 (fr) 2015-09-11
FR3018357B1 true FR3018357B1 (fr) 2018-05-18

Family

ID=51210510

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1451740A Expired - Fee Related FR3018357B1 (fr) 2014-03-04 2014-03-04 Nouvelles lectines et applications pour la detection de marqueurs d'etats pathologiques

Country Status (4)

Country Link
US (1) US10247734B2 (fr)
EP (1) EP3114487A1 (fr)
FR (1) FR3018357B1 (fr)
WO (1) WO2015132699A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420671A (zh) * 2019-06-26 2019-11-08 南京科瑞芯生物科技有限公司 一种凝集素微阵列芯片及其制备方法
FR3116062A1 (fr) 2020-11-06 2022-05-13 Centre National De La Recherche Scientifique (Cnrs) Neolectine specifique et son utilisation pour detecter des microorganismes

Also Published As

Publication number Publication date
EP3114487A1 (fr) 2017-01-11
FR3018357A1 (fr) 2015-09-11
US10247734B2 (en) 2019-04-02
WO2015132699A1 (fr) 2015-09-11
US20170074887A1 (en) 2017-03-16

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