FR2986M - Médicament a base de nouveaux 1-aryl-4-oxo-8-aralcoyle-1,3,8-triazaspiro(4,5)décanes, ainsi que leurs sels a action analgésique. - Google Patents
Médicament a base de nouveaux 1-aryl-4-oxo-8-aralcoyle-1,3,8-triazaspiro(4,5)décanes, ainsi que leurs sels a action analgésique.Info
- Publication number
- FR2986M FR2986M FR948241A FR948241A FR2986M FR 2986 M FR2986 M FR 2986M FR 948241 A FR948241 A FR 948241A FR 948241 A FR948241 A FR 948241A FR 2986 M FR2986 M FR 2986M
- Authority
- FR
- France
- Prior art keywords
- decanes
- triazaspiro
- aralkyl
- oxo
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Wire Processing (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20462362A | 1962-06-22 | 1962-06-22 | |
FR939044 | 1963-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2986M true FR2986M (fr) | 1964-12-07 |
Family
ID=22758700
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1573808D Expired FR1573808A (fr) | 1962-06-22 | 1963-06-22 | |
FR948240A Active FR3043M (fr) | 1962-06-22 | 1963-09-20 | Médicament a base d'une nouvelle série de 1-aryl-4-oxo-1,3,8-triazaspiro-(4,5)-décanes, substitués en position 8 ou leurs sels pour le traitement d'affections mentales. |
FR948243A Active FR2988M (fr) | 1962-06-22 | 1963-09-20 | Médicament pour le traitement d'affections mentales et pour combattre la douleur, a base d'une nouvelle série de 1-phényl-4-oxo-8-(aryl-pentényl)-1,3,8-triazaspiro (4,5) décanes. |
FR948244A Active FR3059M (fr) | 1962-06-22 | 1963-09-20 | Médicament pour le traitement des troubles mentaux et cardiovasculaires contenant une nouvelle série de 1-phényl-4-oxo-1,3,8-triazaspiro-[4,5]-décanes ou leurs sels. |
FR948241A Active FR2986M (fr) | 1962-06-22 | 1963-09-20 | Médicament a base de nouveaux 1-aryl-4-oxo-8-aralcoyle-1,3,8-triazaspiro(4,5)décanes, ainsi que leurs sels a action analgésique. |
FR948242A Active FR2987M (fr) | 1962-06-22 | 1963-09-20 | Médicament a base d'une nouvelle série de 8-[2-(1,4-benzodioxannyl)-méthyl]-1,3,8-triazaspiro (4,5)décanes, ainsi que de leurs sels. |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1573808D Expired FR1573808A (fr) | 1962-06-22 | 1963-06-22 | |
FR948240A Active FR3043M (fr) | 1962-06-22 | 1963-09-20 | Médicament a base d'une nouvelle série de 1-aryl-4-oxo-1,3,8-triazaspiro-(4,5)-décanes, substitués en position 8 ou leurs sels pour le traitement d'affections mentales. |
FR948243A Active FR2988M (fr) | 1962-06-22 | 1963-09-20 | Médicament pour le traitement d'affections mentales et pour combattre la douleur, a base d'une nouvelle série de 1-phényl-4-oxo-8-(aryl-pentényl)-1,3,8-triazaspiro (4,5) décanes. |
FR948244A Active FR3059M (fr) | 1962-06-22 | 1963-09-20 | Médicament pour le traitement des troubles mentaux et cardiovasculaires contenant une nouvelle série de 1-phényl-4-oxo-1,3,8-triazaspiro-[4,5]-décanes ou leurs sels. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR948242A Active FR2987M (fr) | 1962-06-22 | 1963-09-20 | Médicament a base d'une nouvelle série de 8-[2-(1,4-benzodioxannyl)-méthyl]-1,3,8-triazaspiro (4,5)décanes, ainsi que de leurs sels. |
Country Status (9)
Country | Link |
---|---|
BE (1) | BE633914A (fr) |
CH (1) | CH462835A (fr) |
DE (1) | DE1470125C3 (fr) |
DK (1) | DK119880B (fr) |
FI (1) | FI46967C (fr) |
FR (6) | FR1573808A (fr) |
GB (1) | GB1043141A (fr) |
NO (1) | NO117368B (fr) |
SE (1) | SE311019B (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4080328A (en) * | 1971-07-13 | 1978-03-21 | Sumitomo Chemical Company, Limited | N-substituted heterocyclic derivatives and preparation thereof |
BE792187A (fr) * | 1971-12-03 | 1973-03-30 | Sumitomo Chemical Co | Nouveaux derives d'alkylamines |
US4066772A (en) * | 1975-07-21 | 1978-01-03 | Janssen Pharmaceutica N.V. | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
NZ181256A (en) * | 1975-07-21 | 1978-04-28 | Janssen Pharmaceutica Nv | 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives |
DK139684A (da) * | 1983-04-11 | 1984-10-12 | Janssen Pharmaceutica Nv | N-aryl-alpha-amino-carboxamider |
US5703088A (en) * | 1989-08-21 | 1997-12-30 | Beth Israel Deaconess Medical Center, Inc. | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
US5244902A (en) * | 1989-08-21 | 1993-09-14 | Beth Israel Hospital Association | Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses |
US5574041A (en) * | 1990-03-16 | 1996-11-12 | Beth Israel Hospital Association | Use of spiperone derivatives as immunosuppressant agents |
US5693645A (en) * | 1992-12-23 | 1997-12-02 | Beth Israel Deaconess Medical Center, Inc. | Use of spiperone or spiperone derivatives as immunosuppressant agents |
DE19610397A1 (de) * | 1996-03-16 | 1997-09-18 | Krewel Meuselbach Gmbh | Gewinnung von Fluspirilen-Suspensionen |
US6277991B1 (en) | 1998-05-18 | 2001-08-21 | Novo Nordisk A/S | 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
WO1999059997A1 (fr) * | 1998-05-18 | 1999-11-25 | Novo Nordisk A/S | Nouvelles 1,3,8-triazaspiro[4.5]decanones possedant une affinite elevee pour les sous-types du recepteur opioide |
US6262066B1 (en) * | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
ES2237047T3 (es) * | 1998-10-23 | 2005-07-16 | Pfizer Inc. | Compuestos de 1,3,8-triazaespiro(4,5)decanona como agonistas del receptor orl1. |
US7459461B2 (en) | 2001-10-19 | 2008-12-02 | Ortho-Mcneil Pharmaceutical, Inc. | Phosphonic acid compounds as inhibitors of serine proteases |
DE102005038141A1 (de) * | 2005-08-12 | 2007-02-15 | Grünenthal GmbH | Substituierte 8-(3-Aminopropyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-on-Derivate |
DK2582701T3 (en) * | 2010-06-18 | 2017-02-06 | Altos Therapeutics Llc | D2 ANTAGONISTS, SYNTHESIS PROCEDURES AND METHODS OF USE |
IT201800007580A1 (it) * | 2018-07-27 | 2020-01-27 | Maria Cecilia Hospital Spa | Composti 1,3,8-triazaspiro e loro uso come medicamenti |
-
0
- BE BE633914D patent/BE633914A/xx unknown
-
1963
- 1963-06-19 SE SE6834/63A patent/SE311019B/xx unknown
- 1963-06-21 GB GB24824/63A patent/GB1043141A/en not_active Expired
- 1963-06-21 FI FI631267A patent/FI46967C/fi active
- 1963-06-21 NO NO149114A patent/NO117368B/no unknown
- 1963-06-21 DE DE1470125A patent/DE1470125C3/de not_active Expired
- 1963-06-21 CH CH776363A patent/CH462835A/de unknown
- 1963-06-22 FR FR1573808D patent/FR1573808A/fr not_active Expired
- 1963-06-22 DK DK297763AA patent/DK119880B/da unknown
- 1963-09-20 FR FR948240A patent/FR3043M/fr active Active
- 1963-09-20 FR FR948243A patent/FR2988M/fr active Active
- 1963-09-20 FR FR948244A patent/FR3059M/fr active Active
- 1963-09-20 FR FR948241A patent/FR2986M/fr active Active
- 1963-09-20 FR FR948242A patent/FR2987M/fr active Active
Also Published As
Publication number | Publication date |
---|---|
FR2988M (fr) | 1964-12-07 |
NO117368B (fr) | 1969-08-04 |
DE1470125A1 (de) | 1969-05-08 |
DE1470125B2 (fr) | 1979-10-31 |
DE1470125C3 (de) | 1980-07-10 |
FR2987M (fr) | 1964-12-07 |
FR3043M (fr) | 1965-01-04 |
CH462835A (de) | 1968-09-30 |
DK119880B (da) | 1971-03-08 |
FI46967B (fr) | 1973-05-02 |
GB1043141A (en) | 1966-09-21 |
SE311019B (fr) | 1969-05-27 |
FR1573808A (fr) | 1969-07-11 |
FR3059M (fr) | 1965-01-11 |
BE633914A (fr) | |
FI46967C (fi) | 1973-08-10 |
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