FR2979817A1 - Manufacturing bone prosthesis for filling gaps of all/part of bone of patient, comprises digitalizing patient using three-dimensional medical acquisition device by magnetic resonance, defining prosthesis, and manufacturing the prosthesis - Google Patents
Manufacturing bone prosthesis for filling gaps of all/part of bone of patient, comprises digitalizing patient using three-dimensional medical acquisition device by magnetic resonance, defining prosthesis, and manufacturing the prosthesis Download PDFInfo
- Publication number
- FR2979817A1 FR2979817A1 FR1158117A FR1158117A FR2979817A1 FR 2979817 A1 FR2979817 A1 FR 2979817A1 FR 1158117 A FR1158117 A FR 1158117A FR 1158117 A FR1158117 A FR 1158117A FR 2979817 A1 FR2979817 A1 FR 2979817A1
- Authority
- FR
- France
- Prior art keywords
- prosthesis
- bone
- patient
- file
- manufacturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
- B22F10/20—Direct sintering or melting
- B22F10/28—Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F5/00—Manufacture of workpieces or articles from metallic powder characterised by the special shape of the product
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/286—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for scanning or photography techniques, e.g. X-rays, ultrasonics
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
- A61F2002/2889—Maxillary, premaxillary or molar implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30952—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using CAD-CAM techniques or NC-techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
- A61F2002/30962—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using stereolithography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
- B22F10/60—Treatment of workpieces or articles after build-up
- B22F10/66—Treatment of workpieces or articles after build-up by mechanical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
- B22F10/80—Data acquisition or data processing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/25—Process efficiency
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Educational Administration (AREA)
- Educational Technology (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Algebra (AREA)
- Computational Mathematics (AREA)
- Manufacturing & Machinery (AREA)
- Mathematical Analysis (AREA)
- Mathematical Optimization (AREA)
- Mathematical Physics (AREA)
- Pure & Applied Mathematics (AREA)
- Business, Economics & Management (AREA)
- Theoretical Computer Science (AREA)
- Biomedical Technology (AREA)
- Materials Engineering (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Plasma & Fusion (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Geometry (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mechanical Engineering (AREA)
- Neurosurgery (AREA)
- Prostheses (AREA)
Abstract
Description
"Procédé de fabrication d'une prothèse par prototypage rapide" L'invention concerne un procédé de fabrication d'une prothèse osseuse. The invention relates to a method of manufacturing a prosthesis by rapid prototyping.
L'invention concerne plus particulièrement un procédé de fabrication d'une prothèse osseuse destinée à combler les manques osseux de tout ou partie d'un os d'un patient, du type qui comporte au moins : - une première étape de numérisation dudit patient à l'aide d'un dispositif d'acquisition médical en trois dimensions, notamment un scanner ou un dispositif d'imagerie par résonance magnétique, au cours de laquelle on établir un fichier dit "osseux" représentatif des volumes osseux restants du patient, - au moins une deuxième étape de définition de la prothèse au cours de laquelle on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive, selon lequel la prothèse définitive comporte au moins une partie de remplacement des manques osseux du patient, ladite partie étant obtenue à partir du fichier osseux du patient par symétrie de parties osseuses correspondantes intactes du patient et/ou à partir du fichier osseux d'un modèle intact par transposition des parties osseuses dudit modèle, ledit fichier comportant d'une par une succession de sections dont l'empilement détermine la forme d'au moins un support de fabrication de la prothèse à réaliser, une succession de sections de même épaisseur dont l'empilement détermine la forme de la prothèse à réaliser, et une séries d'instructions de déplacement pour un faisceau laser de machine de prototypage rapide destinées à permettre la fabrication du support et de la prothèse, - au moins une troisième étape de fabrication de la prothèse au cours de laquelle on transfère le fichier de prothèse vers une machine de prototypage rapide comportant un canon laser qui est guidé en réponse aux informations du fichier de prothèse dans des couches successives d'une poudre de prototypage afin d'opérer une fusion au laser sélective d'une partie de chaque couche de manière à fabriquer simultanément une section d'au moins un support de fabrication et une section de ladite prothèse, les couches étant alimentées successivement par un distributeur de poudre jusqu'à ce que l'empilement des sections réalisées corresponde à la prothèse, - au moins une quatrième étape de finition au cours de laquelle on débarrasse la prothèse de tout support de fabrication et de toute aspérité. On connait de nombreux exemples de procédé de ce type. Le document EP-A1-2.110.079 décrit et représente un procédé de fabrication d'un masque ou d'une prothèse qui comporte une première étape au cours on déduit des structures 15 anatomiques et/ou pathologiques à partir d'un dispositif d'acquisition médical. Des données d'imagerie obtenues par le dispositif d'acquisition sont utilisées pour créer un contour de surface et sont transmises à un appareil de prototypage rapide compatible qui peut établir un modèle de surface positif ou négatif 20 tel qu'un dispositif de fixation, un masque ou une prothèse ou d'autres instruments à des fins médicales. Dans ce document, comme dans les autres dispositifs connus, la réalisation d'une prothèse à base de prototypage n'est abordée que de manière succincte sans tenir compte des 25 impératifs médicaux qui permettent sa greffe. Parmi ces impératifs il convient de citer l'état de surface de la prothèse, la fidélité de la prothèse par rapport à la partie osseuse qu'elle doit remplacer, notamment pour permettre son implantation dans un environnement existant, le poids, et les 30 capacités de colonisation osseuse. L'invention remédie à ces inconvénients en proposant un procédé du type décrit précédemment mettant en oeuvre un étape de fabrication par prototypage au laser de puissance, seul procédé de fabrication permettant une précision d'exécution permettant d'obtenir un état de surface de la prothèse satisfaisant, une fidélité élevée de la prothèse par rapport à la partie osseuse qu'elle doit remplacer, notamment pour permettre son implantation dans un environnement existant, un poids réduit et des capacités élevées de colonisation osseuse. Dans ce but, l'invention propose un procédé du type décrit précédemment, caractérisé en ce qu'au cours de la troisième étape de fabrication de la prothèse on utilise un canon laser de type laser de puissance, pour obtenir une prothèse de rugosité réduite et d'une précision élevée par rapport aux parties osseuses correspondantes intactes du patient ou du modèle utilisé. Selon d'autres caractéristiques du procédé : - au cours de la troisième étape de fabrication, on utilise une poudre de prototypage synthétique présentant une rigidité élevée à l'issue de la fusion, - au cours de la troisième étape de fabrication, on utilise une poudre de prototypage à base de cobalt/chrome, ou bien de titane, ou bien d'aluminium, - au cours de la deuxième étape de définition de la prothèse on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive, selon lequel la prothèse définitive est constituée uniquement d'une partie de remplacement des manques osseux du patient dont le volume et les dimensions sont limitées au strict rétablissement des fonctions anatomiques du patient, notamment pour alléger le poids de la prothèse, - au cours de la deuxième étape de définition de la prothèse on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive, selon lequel la prothèse définitive est d'un volume extérieur et de dimensions correspondant sensiblement aux volume extérieur et dimensions des parties osseuses correspondantes intactes du patient ou du modèle utilisé, et comporte - au moins une partie pleine, dont le volume réel et les dimensions sont limitées au strict rétablissement des fonctions anatomiques du patient, - au moins un évidement pour alléger le poids de la prothèse, - au cours de la deuxième étape de définition de la prothèse on définit le fichier de prothèse selon un ratio des volumes de partie pleine et d'évidement qui dépend notamment de la poudre de prototypage utilisée et de l'emplacement de la prothèse dans l'os considéré, et qui permet de garantir une rigidité élevée de la partie pleine et une souplesse élevée de l'ensemble de la prothèse, - au cours de la deuxième étape de définition de la prothèse on définit le fichier de prothèse de manière que chaque évidement soit rempli par un maillage tridimensionnel formant une structure alvéolée destinée à permettre la colonisation dudit maillage par des cellules osseuses du patient. L'invention concerne aussi une prothèse osseuse destinée à combler les manques osseux de tout ou partie d'un os d'un patient, obtenue au moins par prototypage rapide dans une machine de prototypage rapide comportant un canon laser qui est guidé en réponse aux informations d'un fichier de prothèse dans des couches successives d'une poudre de prototypage afin d'opérer une fusion au laser sélective d'une partie de chaque couche de manière à fabriquer au moins une section de ladite prothèse, caractérisée en ce qu'elle est obtenue par prototypage rapide dans une machine de prototypage rapide comportant un canon laser de type laser de puissance. Selon d'autres caractéristiques de la prothèse : - la prothèse osseuse est réalisée à partir d'une poudre de prototypage synthétique de rigidité élevée, - la prothèse osseuse est réalisée à base d'une poudre de prototypage à base de cobalt/chrome, ou bien de titane, ou bien d'aluminium, ou de tout autre matériau métallique implantable dans le corps d'un patient, - la prothèse osseuse constitue uniquement d'une partie de remplacement des manques osseux du patient dont le volume et les dimensions sont limitées au strict rétablissement des fonctions anatomiques du patient, - la prothèse osseuse est d'un volume extérieur et de dimensions correspondant sensiblement aux volume extérieur et dimensions des parties osseuses correspondantes intactes du patient ou du modèle utilisé, et comporte au moins une partie pleine, dont le volume réel et les dimensions sont limitées au strict rétablissement des fonctions anatomiques du patient, . au moins un évidement pour alléger son poids. - chaque évidement est rempli par un maillage tridimen- sionnel formant une structure alvéolée destinée à permettre la colonisation dudit maillage par des cellules osseuses du patient. D'autres caractéristiques et avantages de l'invention apparaîtront à la lecture de la description détaillée qui suit pour la 20 compréhension de laquelle on se reportera aux dessins annexés dans lesquels : - les figures 1A à 1C sont des vues successives illustrant la deuxième étape d'un procédé de fabrication d'une prothèse selon l'invention ; 25 - la figure 2A est une vue illustrant la troisième étape d'un procédé de fabrication d'une prothèse selon l'invention ; - la figure 2B est une vue en perspective d'une prothèse de type maxillo-faciale et de ses supports de fabrication. - la figure 3 est une vue en perspective d'une prothèse de 30 type maxillo-faciale selon un premier mode de réalisation de l'invention ; - la figure 4 est une vue en perspective de l'implantation sur le crâne d'un patient de la prothèse de la figure 3 ; - la figure 5 est une vue en perspective d'une prothèse de type maxillo-faciale selon un second mode de réalisation de l'invention ; - la figure 6 est une vue en perspective de l'implantation sur le crâne d'un patient de la prothèse de la figure 5. Dans la description qui va suivre, des chiffres de référence identiques désignent des pièces identiques ou ayant des fonctions similaires. On a représenté à la figure 1 une deuxième étape d'un 10 procédé de fabrication d'une prothèse osseuse destinée à combler les manques osseux de tout ou partie d'un os 10 d'un patient, ici une boîte crânienne 10. De manière connue, un tel procédé comporte au moins une première étape de numérisation dudit patient à l'aide d'un 15 dispositif d'acquisition médical en trois dimensions, notamment un scanner ou un dispositif d'imagerie par résonance magnétique, au cours de laquelle on établir un fichier dit "osseux" représentatif des volumes osseux restants du patient. Dans le cadre de l'invention, cette première étape connue 20 en soi de l'état de la technique comporte notamment l'exportation du fichier en trois dimensions généré par le dispositif d'acquisition médical en trois dimensions vers un logiciel permettant de retravailler ce fichier. En l'occurrence, dans ce cas, et de manière non limitative 25 de l'invention, on exporte fichier en trois dimensions sous la forme d'un fichier de type STL obtenu à l'aide d'un logiciel du type "DICOM VIEWER" permettant de convertir un fichier issu d'un appareil d'acquisition médical en un fichier de type STL ou IGES. Un tel logiciel du type "DICOM VIEWER" est par exemple fourni 30 par la société MATERIALISE. Puis au cours d'une deuxième étape de définition de la prothèse au cours de laquelle on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive. The invention more particularly relates to a method of manufacturing a bone prosthesis intended to fill the bone deficiencies of all or part of a bone of a patient, of the type which comprises at least: a first step of digitizing said patient to using a three-dimensional medical acquisition device, in particular a scanner or a magnetic resonance imaging device, during which a so-called "bone" file representing the remaining bone volumes of the patient is established, at least a second step of defining the prosthesis during which a so-called "prosthesis" file, representative of the shape of the definitive prosthesis, is defined according to which the definitive prosthesis comprises at least one part of replacement of the bone deficiencies of the patient, said part being obtained from the bone file of the patient by symmetry of intact corresponding bone parts of the patient and / or from the bone file of a model the intact by transposition of the bone parts of said model, said file comprising one by a succession of sections, the stack of which determines the shape of at least one support for manufacturing the prosthesis to be produced, a succession of sections of the same thickness of which the stack determines the shape of the prosthesis to be produced, and a series of displacement instructions for a rapid prototyping machine laser beam intended to allow the manufacture of the support and the prosthesis, - at least a third stage of manufacture of the prosthesis during which the prosthesis file is transferred to a rapid prototyping machine comprising a laser cannon which is guided in response to the prosthesis file information in successive layers of a prototyping powder in order to effect a fusion at laser of a portion of each layer so as simultaneously to manufacture a section of at least one manufacturing support and section of said prosthesis, the layers being fed successively by a powder dispenser until the stack of sections made corresponds to the prosthesis, - at least a fourth finishing step during which the prosthesis is removed from any manufacturing support and any roughness. Many examples of such processes are known. The document EP-A1-2.110.079 describes and represents a method of manufacturing a mask or a prosthesis which comprises a first step in the course of which anatomical and / or pathological structures are deduced from a device of FIG. medical acquisition. Imaging data obtained by the acquisition device is used to create a surface contour and is transmitted to a compatible fast prototyping apparatus which can establish a positive or negative surface pattern such as a fixture, mask or prosthesis or other instruments for medical purposes. In this document, as in the other known devices, the production of a prototyping-based prosthesis is approached only briefly without taking into account the medical requirements that allow its grafting. Among these imperatives, it is necessary to mention the surface state of the prosthesis, the fidelity of the prosthesis with respect to the bone part which it must replace, in particular to allow its implantation in an existing environment, the weight, and the capacities of bone colonization. The invention overcomes these drawbacks by proposing a method of the type described above implementing a prototyping step laser power, only manufacturing method allowing a precision of execution to obtain a surface state of the prosthesis satisfactory, a high fidelity of the prosthesis in relation to the bone part it must replace, in particular to allow its implantation in an existing environment, reduced weight and high capacity for bone colonization. For this purpose, the invention proposes a method of the type described above, characterized in that during the third step of manufacturing the prosthesis is used a laser gun laser power type, to obtain a prosthesis of reduced roughness and high accuracy relative to the intact corresponding bone parts of the patient or model used. According to other characteristics of the process: - during the third manufacturing stage, a synthetic prototyping powder with a high rigidity is used after the melting, - during the third stage of manufacture, a prototyping powder based on cobalt / chromium, or titanium, or aluminum, - during the second step of definition of the prosthesis is defined a file called "prosthesis", representative of the shape of the prosthesis definitive, according to which the definitive prosthesis consists solely of a replacement part of the patient's bone deficiencies whose volume and dimensions are limited to the strict restoration of the anatomical functions of the patient, in particular to lighten the weight of the prosthesis, of the second step of definition of the prosthesis is defined a file called "prosthesis", representative of the shape of the final prosthesis, according to which the prosthesis final is an outer volume and dimensions substantially corresponding to the external volume and dimensions of the intact bones of the patient or model used, and comprises - at least one solid part, the actual volume and dimensions of which are limited to the strict restoration of the anatomical functions of the patient, - at least one recess for lightening the weight of the prosthesis, - during the second stage of definition of the prosthesis, the prosthesis file is defined according to a ratio of the volumes of the solid part and the recess which depends in particular on the prototyping powder used and the location of the prosthesis in the bone in question, and which makes it possible to guarantee a high stiffness of the solid part and a high flexibility of the entire prosthesis, - during of the second step of defining the prosthesis, the prosthesis file is defined so that each recess is filled by a sorting mesh. dimensional forming a honeycomb structure for allowing the colonization of said mesh by bone cells of the patient. The invention also relates to a bone prosthesis for filling the bone deficiencies of all or part of a bone of a patient, obtained at least by rapid prototyping in a rapid prototyping machine comprising a laser cannon which is guided in response to the information of a prosthesis file in successive layers of a prototyping powder in order to effect a selective laser melting of a portion of each layer so as to manufacture at least one section of said prosthesis, characterized in that is obtained by rapid prototyping in a rapid prototyping machine comprising a laser laser of the power laser type. According to other characteristics of the prosthesis: the bone prosthesis is made from a synthetic prototyping powder of high rigidity, the bone prosthesis is made based on a cobalt / chromium prototyping powder, or titanium, or aluminum, or any other implantable metal material in the body of a patient, - the bone prosthesis is only a replacement part of the patient's bone deficiencies whose volume and dimensions are limited to the strict restoration of the anatomical functions of the patient, the bone prosthesis is of an external volume and of dimensions substantially corresponding to the external volume and dimensions of the intact corresponding bony parts of the patient or of the model used, and comprises at least one solid part, of which the actual volume and dimensions are limited to the strict restoration of the anatomical functions of the patient,. at least one recess to lighten its weight. each recess is filled by a three-dimensional mesh forming a honeycomb structure intended to allow colonization of said mesh by bone cells of the patient. Other characteristics and advantages of the invention will appear on reading the detailed description which follows for the understanding of which reference will be made to the appended drawings in which: FIGS. 1A to 1C are successive views illustrating the second step of FIG. a method of manufacturing a prosthesis according to the invention; FIG. 2A is a view illustrating the third step of a method of manufacturing a prosthesis according to the invention; FIG. 2B is a perspective view of a maxillofacial prosthesis and its manufacturing supports. FIG. 3 is a perspective view of a maxillofacial prosthesis according to a first embodiment of the invention; FIG. 4 is a perspective view of the implantation on the skull of a patient of the prosthesis of FIG. 3; FIG. 5 is a perspective view of a maxillofacial prosthesis according to a second embodiment of the invention; - Figure 6 is a perspective view of the implantation on the skull of a patient of the prosthesis of Figure 5. In the following description, identical reference numerals designate parts identical or having similar functions. FIG. 1 shows a second step of a method of manufacturing a bone prosthesis intended to fill the bone deficiencies of all or part of a bone of a patient, here a cranial box. As known, such a method comprises at least a first step of digitizing said patient using a three-dimensional medical acquisition device, in particular a scanner or a magnetic resonance imaging device, during which one establish a file called "bone" representative of the remaining bone volumes of the patient. In the context of the invention, this first step known per se of the state of the art comprises in particular the export of the three-dimensional file generated by the medical acquisition device in three dimensions to a software allowing to rework this file. In this case, in this case, and in a nonlimiting manner 25 of the invention, three-dimensional file is exported in the form of an STL type file obtained using software of the "DICOM VIEWER" type. "to convert a file from a medical acquisition device into a file type STL or IGES. Such software of the "DICOM VIEWER" type is for example provided by MATERIALISE. Then during a second step of defining the prosthesis during which we define a so-called "prosthesis" file, representative of the shape of the final prosthesis.
Pour ce faire, un utilise le fichier STL précédemment créé et on le modifie par exemple à l'aide du logiciel MAGICS de la société MATERIALISE, ou tout autre logiciel similaire. Cette deuxième étape implique en premier lieu nettoyer le fichier STL en retirant les erreurs de numérisation et en lissant les contours de l'image obtenue. Puis on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive. Comme l'illustre la figure 1A, qui représente la boîte crânienne 10 d'un patient, à laquelle il manque une partie correspondant à un manque osseux 12, au cours de cette deuxième étape on définit la prothèse définitive 14, appelée épithèse dans ce type de reconstruction maxillo-faciale, comme comportant au moins une partie de remplacement des manques osseux du patient. A cet effet, comme représenté à la figure 1 B, à partir du fichier osseux du patient, on isole une partie 16 osseuse intacte de la boîte crânienne du patient et on définit une image symétrique 18 de cette partie 16, qui permettra d'élaborer la prothèse définitive 14 qui pourra être ajustée à la boîte crânienne du patient, comme représenté à la figure 1C. En variante (non représentée) de cette première étape, il est possible de définir la prothèse définitive 14, isolant puis en transposant les parties osseuses d'un modèle intact. Une fois la conception faite, la prothèse 14 à réaliser est transférée dans une zone de préparation du logiciel MAGICS dans la position où elle sera construite. Le logiciel calcule des supports 26 de fabrication qui seront destinés à soutenir la prothèse 14 lors de sa fabrication, comme représenté la figure 2B. Les supports 26 sont alors décomposés en sections devant 30 être réalisées par fusion de couches successives de poudre de prototypage. La découpe des supports en sections ou "slicing" est réalisée suivant des épaisseurs variables de couches, typiquement de l'ordre de 25, 30, 50 ou 75 microns. Les différentes tranches des supports 26 sont alors mémorisées. Une fois les données relatives aux supports 26 enregistrées, une décomposition analogue est faite pour la prothèse 14. Pour ce faire on utilise le logiciel REALIZER de la société REALIZER ou VISCAM de la société MARCAM. La prothèse 14 est alors elle aussi décomposée en sections devant être réalisées par fusion de couches successives de poudre de prototypage pour former une succession de sections dont l'empilement détermine la forme de la prothèse à réaliser, en gardant pour chaque couche la même épaisseur de couche que pour les supports 26. Le logiciel établit enfin une stratégie de fusion, c'est-à-dire l'ensemble des instructions de déplacement qui seront données au faisceau laser pour réaliser les supports 26 et la prothèse 14. Comme l'illustre la figure 2A, le procédé comporte de manière connue au moins une troisième étape de fabrication de la prothèse au cours de laquelle on transfère le fichier de prothèse vers une machine 20 de prototypage rapide comportant un canon laser 22 qui est guidé en réponse aux informations du fichier de prothèse dans des couches successives d'une poudre 24 de prototypage afin d'opérer une fusion au laser sélective d'une partie de chaque couche de manière à fabriquer une section d'au moins un support 26 de fabrication et/ou une section 28 de ladite prothèse. Les couches de poudre sont alimentées successivement par un distributeur de poudre (non représenté) jusqu'à ce que l'empilement des sections réalisées corresponde à la prothèse 14. A l'issue de l'exposition de chaque couche au faisceau laser, un racleur 23 étale les couches de poudre pour répartir la poudre de prototypage selon une couche homogène, prélablement à l'exposition suivante de ladite couche au faisceau laser. Le résultat est un ensemble tel que représenté à la figure 2B, comportant la prothèse 14 et les supports 26. To do this, one uses the previously created STL file and modifies it for example using MAGICS software from MATERIALISE, or any other similar software. This second step involves first cleaning the STL file by removing the scanning errors and smoothing out the edges of the resulting image. Then we define a file called "prosthesis", representative of the shape of the final prosthesis. As illustrated in FIG. 1A, which represents the cranial box 10 of a patient, which lacks a part corresponding to a bone deficiency 12, during this second stage the definitive prosthesis 14, called epithesis in this type, is defined. maxillofacial reconstruction, as comprising at least a replacement part of the patient's bone deficiencies. For this purpose, as shown in FIG. 1B, from the patient's bone file, an intact bone part 16 is isolated from the cranial box of the patient and a symmetrical image 18 of this part 16 is defined, which will make it possible to elaborate the final prosthesis 14 which can be adjusted to the skull of the patient, as shown in Figure 1C. Alternatively (not shown) of this first step, it is possible to define the final prosthesis 14, isolating and then transposing the bone parts of an intact model. Once the design is done, the prosthesis 14 to be produced is transferred to a preparation area of the MAGICS software in the position where it will be constructed. The software calculates manufacturing supports 26 which will be intended to support the prosthesis 14 during its manufacture, as represented in FIG. 2B. The supports 26 are then decomposed into sections to be made by melting successive layers of prototyping powder. The cutting of the supports in sections or "slicing" is carried out according to varying thicknesses of layers, typically of the order of 25, 30, 50 or 75 microns. The different slices of the supports 26 are then stored. Once the data relating to the media 26 has been recorded, a similar decomposition is made for the prosthesis 14. To do this, the software REALIZER from the company REALIZER or VISCAM from the company MARCAM is used. The prosthesis 14 is then also decomposed into sections to be made by fusing successive layers of prototyping powder to form a succession of sections, the stack of which determines the shape of the prosthesis to be produced, keeping for each layer the same thickness of The software finally establishes a fusion strategy, that is to say the set of displacement instructions that will be given to the laser beam to produce the supports 26 and the prosthesis 14. As shown in FIG. 2A, the method comprises in known manner at least a third step of manufacturing the prosthesis in which the prosthesis file is transferred to a rapid prototyping machine 20 comprising a laser gun 22 which is guided in response to the information of the prosthesis file in successive layers of a prototyping powder 24 to perform a selective laser fusion of a portion of each layer so as to manufacture a section of at least one support 26 of manufacture and / or a section 28 of said prosthesis. The layers of powder are fed successively by a powder distributor (not shown) until the stack of the sections made corresponds to the prosthesis 14. At the end of the exposure of each layer to the laser beam, a scraper 23 spreads the layers of powder to distribute the prototyping powder in a homogeneous layer, prior to the next exposure of said layer to the laser beam. The result is an assembly as shown in FIG. 2B, comprising the prosthesis 14 and the supports 26.
Enfin, le procédé selon l'invention comporte au moins une quatrième étape de finition (non représentée) au cours de laquelle on débarrasse la prothèse 14 de tout support de fabrication 26 et de toute aspérité. Finally, the method according to the invention comprises at least a fourth finishing step (not shown) during which the prosthesis 14 is cleared of any manufacturing support 26 and any roughness.
Cette étape peut faire intervenir une opération de fraisage ou toute opération équivalente de finition manuelle, notamment une finition manuelle sur un microtour. Ce procédé connu de l'état de la technique a jusqu'à présent été utilisé de manière non satisfaisante à l'aide de machines de prototypage laser fonctionnant à l'aide de lasers à faisceau d'électrons, réalisant la fusion de poudre de titane exclusivement sous vide. Cette technologie ne permet pas la restitution des caractéristiques osseuses du patient avec une précision suffisante pour permettre une réimplantation de la prothèse dans le corps. L'invention remédie cet inconvénient en utilisant un laser et des matériaux aptes à obtenir la précision suffisante. Dans ce but, l'invention propose un procédé du type décrit précédemment, caractérisé en ce qu'au cours de la troisième étape de fabrication de la prothèse on utilise un canon laser 22 de type laser de puissance, pour obtenir une prothèse de rugosité réduite et d'une précision élevée par rapport aux parties osseuses correspondantes intactes du patient ou du modèle utilisé. L'utilisation d'un canon laser 22 de puissance permet par exemple d'obtenir une précision par rapport aux cotes originales du modèles comprise dans une fourchette de 801.1m, et définir ainsi une prothèse d'une rugosité Ra égale à 5 après finition. Selon un premier mode de réalisation de la troisième étape on utilise une poudre de prototypage synthétique présentant une 30 rigidité élevée à l'issue de la fusion. Cette poudre permet d'obtenir une prothèse 14 légère. Selon un second mode de réalisation de la troisième étape, au cours de la troisième étape de fabrication, on utilise une poudre de prototypage métallique. Il s'agit en l'occurrence de préférence d'une poudre à base de cobalt/chrome, ou bien de titane, ou encore d'aluminium. Plus généralement il s'agit de tout type de poudre métallique implantable dans le corps sans effets secondaires sur la santé du patient. Selon un mode de réalisation préféré de l'invention, la prothèse 14 est conçue de manière à être plus légère que les prothèses connues de l'état de la technique. This step may involve a milling operation or any equivalent manual finishing operation, including a manual finish on a microtour. This known method of the state of the art has hitherto been used unsatisfactorily using laser prototyping machines operating with the aid of electron beam lasers, carrying out the melting of titanium powder. exclusively under vacuum. This technology does not allow the restoration of the patient's bone characteristics with sufficient precision to allow reimplantation of the prosthesis in the body. The invention overcomes this disadvantage by using a laser and materials capable of obtaining sufficient accuracy. For this purpose, the invention proposes a method of the type described above, characterized in that during the third step of manufacturing the prosthesis is used a laser gun 22 of the power laser type, to obtain a reduced roughness prosthesis and high precision with respect to the intact, intact bone portions of the patient or model used. The use of a laser gun 22 of power allows for example to obtain a precision compared to the original dimensions of the models within a range of 801.1m, and thus define a prosthesis with a roughness Ra equal to 5 after finishing. According to a first embodiment of the third step, a synthetic prototyping powder having a high rigidity at the end of the melting is used. This powder makes it possible to obtain a light prosthesis 14. According to a second embodiment of the third step, during the third manufacturing step, a metal prototyping powder is used. This is preferably a powder based on cobalt / chromium, or titanium, or aluminum. More generally it is any type of implantable metal powder in the body without side effects on the health of the patient. According to a preferred embodiment of the invention, the prosthesis 14 is designed to be lighter than the prostheses known from the state of the art.
Ainsi, selon un premier mode de réalisation de la deuxième étape qui a été précédemment décrite, au cours de la deuxième étape de définition de la prothèse on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive, selon lequel la prothèse définitive est d'un volume extérieur et de dimensions correspondant sensiblement aux volume extérieur et dimensions des parties osseuses correspondantes intactes du patient ou du modèle utilisé, et comporte - au moins une partie pleine 30, dont le volume réel et les dimensions sont limités au strict rétablissement des fonctions anatomiques du patient, - au moins un évidement 32 pour alléger le poids de la prothèse. Une telle prothèse ou épithèse a été représentée à la figure 3 et son implantation sur le crâne 10 du patient a été représenté à la figure 4 . Plus particulièrement, au cours de la deuxième étape de définition de la prothèse on peut définir le fichier de prothèse selon un ratio des volumes de partie pleine 30 et de partie d'évidement 32 qui dépend notamment de la poudre de prototypage utilisée et de l'emplacement de la prothèse 14 dans l'os considéré, et qui permet de garantir une rigidité élevée de la partie pleine 30 et une souplesse élevée de l'ensemble de la prothèse 14. Thus, according to a first embodiment of the second step which has been previously described, during the second step of defining the prosthesis is defined a so-called "prosthesis" file, representative of the shape of the final prosthesis, according to which the final prosthesis is of an external volume and of dimensions substantially corresponding to the external volume and dimensions of the intact corresponding bony parts of the patient or of the model used, and comprises - at least one solid part 30, whose actual volume and dimensions are limited the strict restoration of the anatomical functions of the patient, - at least one recess 32 to lighten the weight of the prosthesis. Such a prosthesis or epithesis has been shown in FIG. 3 and its implantation on the skull 10 of the patient has been represented in FIG. 4. More particularly, during the second step of defining the prosthesis, the prosthesis file can be defined according to a ratio of the volumes of the solid portion 30 and of the recess portion 32 which depends in particular on the prototyping powder used and on the location of the prosthesis 14 in the bone in question, and which ensures a high rigidity of the solid part 30 and high flexibility of the entire prosthesis 14.
Le procédé peut encore être amélioré en conservant le principe d'une prothèse 14 munie de partie d'évidement 14, mais en concevant ces parties selon une structure alvéolée. Ainsi, selon cette variante du procédé de fabrication selon l'invention, on définit le fichier de prothèse de manière que chaque évidement 32 soit rempli par un maillage tridimensionnel 34 formant une structure alvéolée. Cette structure alvéolée est destinée conférer plus de rigidité à la prothèse tout en permettre la colonisation dudit maillage 34 par des cellules osseuses du patient au cours de sa convalescence. La prothèse 14 peut ainsi s'intégrer progressivement dans le tissu osseux du patient. En variante, comme l'illustrent les figures 5 et 6, au cours de la deuxième étape de définition de la prothèse on définit un fichier dit "de prothèse", représentatif de la forme de la prothèse définitive, selon lequel la prothèse définitive 14 est constituée uniquement d'une partie 30 de remplacement des manques osseux du patient dont le volume et les dimensions sont limitées au strict rétablissement des fonctions anatomiques du patient, notamment pour alléger le poids de la prothèse 14. Une telle prothèse a été représentée à la figure 5, et son intégration à la boîte crânienne 10 du patient a été représentée à la figure 6. On remarquera à cet effet que la prothèse 14 peut comporter a ses extrémités libres 36 des perçages 38 permettant le passage de vis destinées à être visées dans la partie saine de la boîte crânienne 10. L'invention propose donc un procédé innovant permettant notamment la reconstruction osseuse d'un patient gravement atteint par la fabrication d'une prothèse fonctionnellement identique aux parties manquantes de l'élément osseux à réparer.30 The method can be further improved by maintaining the principle of a prosthesis 14 provided with recess portion 14, but by designing these parts in a honeycomb structure. Thus, according to this variant of the manufacturing method according to the invention, the prosthesis file is defined so that each recess 32 is filled by a three-dimensional mesh 34 forming a honeycomb structure. This honeycomb structure is intended to confer more rigidity to the prosthesis while allowing the colonization of said mesh 34 by bone cells of the patient during his convalescence. The prosthesis 14 can thus gradually integrate into the bone tissue of the patient. As a variant, as illustrated in FIGS. 5 and 6, during the second step of defining the prosthesis, a so-called "prosthesis" file, representative of the shape of the definitive prosthesis, is defined according to which the definitive prosthesis 14 is consisting only of a replacement portion of the patient's bone deficiencies whose volume and dimensions are limited to the strict restoration of the anatomical functions of the patient, in particular to lighten the weight of the prosthesis 14. Such a prosthesis has been shown in FIG. 5, and its integration with the cranial box 10 of the patient has been shown in Figure 6. It will be noted for this purpose that the prosthesis 14 may have at its free ends 36 holes 38 for the passage of screws intended to be referred in the The invention therefore proposes an innovative method that makes it possible in particular to reconstruct the bone of a patient who has been severely affected. t by the manufacture of a prosthesis functionally identical to the missing parts of the bone element to be repaired.
Claims (13)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1158117A FR2979817B1 (en) | 2011-09-13 | 2011-09-13 | PROCESS FOR PRODUCING PROSTHESIS BY RAPID PROTOTYPING |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1158117A FR2979817B1 (en) | 2011-09-13 | 2011-09-13 | PROCESS FOR PRODUCING PROSTHESIS BY RAPID PROTOTYPING |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2979817A1 true FR2979817A1 (en) | 2013-03-15 |
FR2979817B1 FR2979817B1 (en) | 2014-08-01 |
Family
ID=45319268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1158117A Expired - Fee Related FR2979817B1 (en) | 2011-09-13 | 2011-09-13 | PROCESS FOR PRODUCING PROSTHESIS BY RAPID PROTOTYPING |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2979817B1 (en) |
Cited By (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8956364B2 (en) | 2011-04-29 | 2015-02-17 | Biomet Manufacturing, Llc | Patient-specific partial knee guides and other instruments |
US8979936B2 (en) | 2006-06-09 | 2015-03-17 | Biomet Manufacturing, Llc | Patient-modified implant |
US9060788B2 (en) | 2012-12-11 | 2015-06-23 | Biomet Manufacturing, Llc | Patient-specific acetabular guide for anterior approach |
US9066734B2 (en) | 2011-08-31 | 2015-06-30 | Biomet Manufacturing, Llc | Patient-specific sacroiliac guides and associated methods |
US9084618B2 (en) | 2011-06-13 | 2015-07-21 | Biomet Manufacturing, Llc | Drill guides for confirming alignment of patient-specific alignment guides |
US9113971B2 (en) | 2006-02-27 | 2015-08-25 | Biomet Manufacturing, Llc | Femoral acetabular impingement guide |
US9173661B2 (en) | 2006-02-27 | 2015-11-03 | Biomet Manufacturing, Llc | Patient specific alignment guide with cutting surface and laser indicator |
US9173666B2 (en) | 2011-07-01 | 2015-11-03 | Biomet Manufacturing, Llc | Patient-specific-bone-cutting guidance instruments and methods |
US9204977B2 (en) | 2012-12-11 | 2015-12-08 | Biomet Manufacturing, Llc | Patient-specific acetabular guide for anterior approach |
US9237950B2 (en) | 2012-02-02 | 2016-01-19 | Biomet Manufacturing, Llc | Implant with patient-specific porous structure |
US9241745B2 (en) | 2011-03-07 | 2016-01-26 | Biomet Manufacturing, Llc | Patient-specific femoral version guide |
US9271744B2 (en) | 2010-09-29 | 2016-03-01 | Biomet Manufacturing, Llc | Patient-specific guide for partial acetabular socket replacement |
US9289253B2 (en) | 2006-02-27 | 2016-03-22 | Biomet Manufacturing, Llc | Patient-specific shoulder guide |
US9295497B2 (en) | 2011-08-31 | 2016-03-29 | Biomet Manufacturing, Llc | Patient-specific sacroiliac and pedicle guides |
US9301812B2 (en) | 2011-10-27 | 2016-04-05 | Biomet Manufacturing, Llc | Methods for patient-specific shoulder arthroplasty |
US9339278B2 (en) | 2006-02-27 | 2016-05-17 | Biomet Manufacturing, Llc | Patient-specific acetabular guides and associated instruments |
US9345548B2 (en) | 2006-02-27 | 2016-05-24 | Biomet Manufacturing, Llc | Patient-specific pre-operative planning |
US9351743B2 (en) | 2011-10-27 | 2016-05-31 | Biomet Manufacturing, Llc | Patient-specific glenoid guides |
US9386993B2 (en) | 2011-09-29 | 2016-07-12 | Biomet Manufacturing, Llc | Patient-specific femoroacetabular impingement instruments and methods |
US9393028B2 (en) | 2009-08-13 | 2016-07-19 | Biomet Manufacturing, Llc | Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis |
US9408616B2 (en) | 2014-05-12 | 2016-08-09 | Biomet Manufacturing, Llc | Humeral cut guide |
US9427320B2 (en) | 2011-08-04 | 2016-08-30 | Biomet Manufacturing, Llc | Patient-specific pelvic implants for acetabular reconstruction |
US9445907B2 (en) | 2011-03-07 | 2016-09-20 | Biomet Manufacturing, Llc | Patient-specific tools and implants |
US9451973B2 (en) | 2011-10-27 | 2016-09-27 | Biomet Manufacturing, Llc | Patient specific glenoid guide |
US9456833B2 (en) | 2010-02-26 | 2016-10-04 | Biomet Sports Medicine, Llc | Patient-specific osteotomy devices and methods |
US9474539B2 (en) | 2011-04-29 | 2016-10-25 | Biomet Manufacturing, Llc | Patient-specific convertible guides |
US9480580B2 (en) | 2006-02-27 | 2016-11-01 | Biomet Manufacturing, Llc | Patient-specific acetabular alignment guides |
US9480490B2 (en) | 2006-02-27 | 2016-11-01 | Biomet Manufacturing, Llc | Patient-specific guides |
US9498233B2 (en) | 2013-03-13 | 2016-11-22 | Biomet Manufacturing, Llc. | Universal acetabular guide and associated hardware |
US9517145B2 (en) | 2013-03-15 | 2016-12-13 | Biomet Manufacturing, Llc | Guide alignment system and method |
US9522010B2 (en) | 2006-02-27 | 2016-12-20 | Biomet Manufacturing, Llc | Patient-specific orthopedic instruments |
US9539013B2 (en) | 2006-02-27 | 2017-01-10 | Biomet Manufacturing, Llc | Patient-specific elbow guides and associated methods |
EP3120796A1 (en) | 2015-07-17 | 2017-01-25 | Mimedis AG | Method and system for the manufacture of an implant |
US9554910B2 (en) | 2011-10-27 | 2017-01-31 | Biomet Manufacturing, Llc | Patient-specific glenoid guide and implants |
US9561040B2 (en) | 2014-06-03 | 2017-02-07 | Biomet Manufacturing, Llc | Patient-specific glenoid depth control |
US9572590B2 (en) | 2006-10-03 | 2017-02-21 | Biomet Uk Limited | Surgical instrument |
US9579107B2 (en) | 2013-03-12 | 2017-02-28 | Biomet Manufacturing, Llc | Multi-point fit for patient specific guide |
US9662127B2 (en) | 2006-02-27 | 2017-05-30 | Biomet Manufacturing, Llc | Patient-specific acetabular guides and associated instruments |
US9662216B2 (en) | 2006-02-27 | 2017-05-30 | Biomet Manufacturing, Llc | Patient-specific hip joint devices |
US9717510B2 (en) | 2011-04-15 | 2017-08-01 | Biomet Manufacturing, Llc | Patient-specific numerically controlled instrument |
US9757238B2 (en) | 2011-06-06 | 2017-09-12 | Biomet Manufacturing, Llc | Pre-operative planning and manufacturing method for orthopedic procedure |
US9795399B2 (en) | 2006-06-09 | 2017-10-24 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US9820868B2 (en) | 2015-03-30 | 2017-11-21 | Biomet Manufacturing, Llc | Method and apparatus for a pin apparatus |
US9826994B2 (en) | 2014-09-29 | 2017-11-28 | Biomet Manufacturing, Llc | Adjustable glenoid pin insertion guide |
US9826981B2 (en) | 2013-03-13 | 2017-11-28 | Biomet Manufacturing, Llc | Tangential fit of patient-specific guides |
US9833245B2 (en) | 2014-09-29 | 2017-12-05 | Biomet Sports Medicine, Llc | Tibial tubercule osteotomy |
US9839438B2 (en) | 2013-03-11 | 2017-12-12 | Biomet Manufacturing, Llc | Patient-specific glenoid guide with a reusable guide holder |
US9839436B2 (en) | 2014-06-03 | 2017-12-12 | Biomet Manufacturing, Llc | Patient-specific glenoid depth control |
US9861387B2 (en) | 2006-06-09 | 2018-01-09 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US9907659B2 (en) | 2007-04-17 | 2018-03-06 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US9918740B2 (en) | 2006-02-27 | 2018-03-20 | Biomet Manufacturing, Llc | Backup surgical instrument system and method |
US9926072B2 (en) | 2014-09-30 | 2018-03-27 | Safran Landing Systems Uk Ltd | Aerospace component and method for producing an aerospace component |
US9968376B2 (en) | 2010-11-29 | 2018-05-15 | Biomet Manufacturing, Llc | Patient-specific orthopedic instruments |
US10159498B2 (en) | 2008-04-16 | 2018-12-25 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US10226262B2 (en) | 2015-06-25 | 2019-03-12 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
US10282488B2 (en) | 2014-04-25 | 2019-05-07 | Biomet Manufacturing, Llc | HTO guide with optional guided ACL/PCL tunnels |
US10278711B2 (en) | 2006-02-27 | 2019-05-07 | Biomet Manufacturing, Llc | Patient-specific femoral guide |
US10492798B2 (en) | 2011-07-01 | 2019-12-03 | Biomet Manufacturing, Llc | Backup kit for a patient-specific arthroplasty kit assembly |
US10568647B2 (en) | 2015-06-25 | 2020-02-25 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
US10603179B2 (en) | 2006-02-27 | 2020-03-31 | Biomet Manufacturing, Llc | Patient-specific augments |
US10722310B2 (en) | 2017-03-13 | 2020-07-28 | Zimmer Biomet CMF and Thoracic, LLC | Virtual surgery planning system and method |
US11179165B2 (en) | 2013-10-21 | 2021-11-23 | Biomet Manufacturing, Llc | Ligament guide registration |
US11419618B2 (en) | 2011-10-27 | 2022-08-23 | Biomet Manufacturing, Llc | Patient-specific glenoid guides |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104473705A (en) * | 2014-12-03 | 2015-04-01 | 卢清君 | Head maxillofacial bone implant and method for quickly molding same |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6454811B1 (en) * | 1998-10-12 | 2002-09-24 | Massachusetts Institute Of Technology | Composites for tissue regeneration and methods of manufacture thereof |
GB2395927A (en) * | 2002-12-02 | 2004-06-09 | Ono & Co Ltd | Producing artificial bones by laser sintering |
US20080288083A1 (en) * | 2005-10-26 | 2008-11-20 | Robert Axelsson | Osseointegration Implant |
EP2110079A1 (en) * | 2008-04-14 | 2009-10-21 | DKFZ Deutsches Krebsforschungszentrum, Stiftung des Öffentlichen Rechts | Method to derive anatomical and/or pathological structures from data of imaging technologies |
WO2011056995A2 (en) * | 2009-11-04 | 2011-05-12 | Conformis, Inc. | Patient-adapted and improved orthopedic implants, designs and related tools |
-
2011
- 2011-09-13 FR FR1158117A patent/FR2979817B1/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6454811B1 (en) * | 1998-10-12 | 2002-09-24 | Massachusetts Institute Of Technology | Composites for tissue regeneration and methods of manufacture thereof |
GB2395927A (en) * | 2002-12-02 | 2004-06-09 | Ono & Co Ltd | Producing artificial bones by laser sintering |
US20080288083A1 (en) * | 2005-10-26 | 2008-11-20 | Robert Axelsson | Osseointegration Implant |
EP2110079A1 (en) * | 2008-04-14 | 2009-10-21 | DKFZ Deutsches Krebsforschungszentrum, Stiftung des Öffentlichen Rechts | Method to derive anatomical and/or pathological structures from data of imaging technologies |
WO2011056995A2 (en) * | 2009-11-04 | 2011-05-12 | Conformis, Inc. | Patient-adapted and improved orthopedic implants, designs and related tools |
Cited By (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9480580B2 (en) | 2006-02-27 | 2016-11-01 | Biomet Manufacturing, Llc | Patient-specific acetabular alignment guides |
US10426492B2 (en) | 2006-02-27 | 2019-10-01 | Biomet Manufacturing, Llc | Patient specific alignment guide with cutting surface and laser indicator |
US10390845B2 (en) | 2006-02-27 | 2019-08-27 | Biomet Manufacturing, Llc | Patient-specific shoulder guide |
US10507029B2 (en) | 2006-02-27 | 2019-12-17 | Biomet Manufacturing, Llc | Patient-specific acetabular guides and associated instruments |
US10278711B2 (en) | 2006-02-27 | 2019-05-07 | Biomet Manufacturing, Llc | Patient-specific femoral guide |
US9113971B2 (en) | 2006-02-27 | 2015-08-25 | Biomet Manufacturing, Llc | Femoral acetabular impingement guide |
US9173661B2 (en) | 2006-02-27 | 2015-11-03 | Biomet Manufacturing, Llc | Patient specific alignment guide with cutting surface and laser indicator |
US10603179B2 (en) | 2006-02-27 | 2020-03-31 | Biomet Manufacturing, Llc | Patient-specific augments |
US10743937B2 (en) | 2006-02-27 | 2020-08-18 | Biomet Manufacturing, Llc | Backup surgical instrument system and method |
US10206695B2 (en) | 2006-02-27 | 2019-02-19 | Biomet Manufacturing, Llc | Femoral acetabular impingement guide |
US9918740B2 (en) | 2006-02-27 | 2018-03-20 | Biomet Manufacturing, Llc | Backup surgical instrument system and method |
US9913734B2 (en) | 2006-02-27 | 2018-03-13 | Biomet Manufacturing, Llc | Patient-specific acetabular alignment guides |
US9289253B2 (en) | 2006-02-27 | 2016-03-22 | Biomet Manufacturing, Llc | Patient-specific shoulder guide |
US9700329B2 (en) | 2006-02-27 | 2017-07-11 | Biomet Manufacturing, Llc | Patient-specific orthopedic instruments |
US9662216B2 (en) | 2006-02-27 | 2017-05-30 | Biomet Manufacturing, Llc | Patient-specific hip joint devices |
US9339278B2 (en) | 2006-02-27 | 2016-05-17 | Biomet Manufacturing, Llc | Patient-specific acetabular guides and associated instruments |
US9345548B2 (en) | 2006-02-27 | 2016-05-24 | Biomet Manufacturing, Llc | Patient-specific pre-operative planning |
US9662127B2 (en) | 2006-02-27 | 2017-05-30 | Biomet Manufacturing, Llc | Patient-specific acetabular guides and associated instruments |
US11534313B2 (en) | 2006-02-27 | 2022-12-27 | Biomet Manufacturing, Llc | Patient-specific pre-operative planning |
US9539013B2 (en) | 2006-02-27 | 2017-01-10 | Biomet Manufacturing, Llc | Patient-specific elbow guides and associated methods |
US9522010B2 (en) | 2006-02-27 | 2016-12-20 | Biomet Manufacturing, Llc | Patient-specific orthopedic instruments |
US9480490B2 (en) | 2006-02-27 | 2016-11-01 | Biomet Manufacturing, Llc | Patient-specific guides |
US9861387B2 (en) | 2006-06-09 | 2018-01-09 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US11576689B2 (en) | 2006-06-09 | 2023-02-14 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US8979936B2 (en) | 2006-06-09 | 2015-03-17 | Biomet Manufacturing, Llc | Patient-modified implant |
US10893879B2 (en) | 2006-06-09 | 2021-01-19 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US10206697B2 (en) | 2006-06-09 | 2019-02-19 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US9795399B2 (en) | 2006-06-09 | 2017-10-24 | Biomet Manufacturing, Llc | Patient-specific knee alignment guide and associated method |
US9993344B2 (en) | 2006-06-09 | 2018-06-12 | Biomet Manufacturing, Llc | Patient-modified implant |
US9572590B2 (en) | 2006-10-03 | 2017-02-21 | Biomet Uk Limited | Surgical instrument |
US9907659B2 (en) | 2007-04-17 | 2018-03-06 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US11554019B2 (en) | 2007-04-17 | 2023-01-17 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US10159498B2 (en) | 2008-04-16 | 2018-12-25 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US10052110B2 (en) | 2009-08-13 | 2018-08-21 | Biomet Manufacturing, Llc | Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis |
US9393028B2 (en) | 2009-08-13 | 2016-07-19 | Biomet Manufacturing, Llc | Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis |
US9839433B2 (en) | 2009-08-13 | 2017-12-12 | Biomet Manufacturing, Llc | Device for the resection of bones, method for producing such a device, endoprosthesis suited for this purpose and method for producing such an endoprosthesis |
US11324522B2 (en) | 2009-10-01 | 2022-05-10 | Biomet Manufacturing, Llc | Patient specific alignment guide with cutting surface and laser indicator |
US9456833B2 (en) | 2010-02-26 | 2016-10-04 | Biomet Sports Medicine, Llc | Patient-specific osteotomy devices and methods |
US10893876B2 (en) | 2010-03-05 | 2021-01-19 | Biomet Manufacturing, Llc | Method and apparatus for manufacturing an implant |
US9271744B2 (en) | 2010-09-29 | 2016-03-01 | Biomet Manufacturing, Llc | Patient-specific guide for partial acetabular socket replacement |
US10098648B2 (en) | 2010-09-29 | 2018-10-16 | Biomet Manufacturing, Llc | Patient-specific guide for partial acetabular socket replacement |
US11234719B2 (en) | 2010-11-03 | 2022-02-01 | Biomet Manufacturing, Llc | Patient-specific shoulder guide |
US9968376B2 (en) | 2010-11-29 | 2018-05-15 | Biomet Manufacturing, Llc | Patient-specific orthopedic instruments |
US9445907B2 (en) | 2011-03-07 | 2016-09-20 | Biomet Manufacturing, Llc | Patient-specific tools and implants |
US9241745B2 (en) | 2011-03-07 | 2016-01-26 | Biomet Manufacturing, Llc | Patient-specific femoral version guide |
US9743935B2 (en) | 2011-03-07 | 2017-08-29 | Biomet Manufacturing, Llc | Patient-specific femoral version guide |
US9717510B2 (en) | 2011-04-15 | 2017-08-01 | Biomet Manufacturing, Llc | Patient-specific numerically controlled instrument |
US9474539B2 (en) | 2011-04-29 | 2016-10-25 | Biomet Manufacturing, Llc | Patient-specific convertible guides |
US9743940B2 (en) | 2011-04-29 | 2017-08-29 | Biomet Manufacturing, Llc | Patient-specific partial knee guides and other instruments |
US8956364B2 (en) | 2011-04-29 | 2015-02-17 | Biomet Manufacturing, Llc | Patient-specific partial knee guides and other instruments |
US9757238B2 (en) | 2011-06-06 | 2017-09-12 | Biomet Manufacturing, Llc | Pre-operative planning and manufacturing method for orthopedic procedure |
US9084618B2 (en) | 2011-06-13 | 2015-07-21 | Biomet Manufacturing, Llc | Drill guides for confirming alignment of patient-specific alignment guides |
US9687261B2 (en) | 2011-06-13 | 2017-06-27 | Biomet Manufacturing, Llc | Drill guides for confirming alignment of patient-specific alignment guides |
US10492798B2 (en) | 2011-07-01 | 2019-12-03 | Biomet Manufacturing, Llc | Backup kit for a patient-specific arthroplasty kit assembly |
US11253269B2 (en) | 2011-07-01 | 2022-02-22 | Biomet Manufacturing, Llc | Backup kit for a patient-specific arthroplasty kit assembly |
US9173666B2 (en) | 2011-07-01 | 2015-11-03 | Biomet Manufacturing, Llc | Patient-specific-bone-cutting guidance instruments and methods |
US9668747B2 (en) | 2011-07-01 | 2017-06-06 | Biomet Manufacturing, Llc | Patient-specific-bone-cutting guidance instruments and methods |
US9427320B2 (en) | 2011-08-04 | 2016-08-30 | Biomet Manufacturing, Llc | Patient-specific pelvic implants for acetabular reconstruction |
US9066734B2 (en) | 2011-08-31 | 2015-06-30 | Biomet Manufacturing, Llc | Patient-specific sacroiliac guides and associated methods |
US9603613B2 (en) | 2011-08-31 | 2017-03-28 | Biomet Manufacturing, Llc | Patient-specific sacroiliac guides and associated methods |
US9295497B2 (en) | 2011-08-31 | 2016-03-29 | Biomet Manufacturing, Llc | Patient-specific sacroiliac and pedicle guides |
US9439659B2 (en) | 2011-08-31 | 2016-09-13 | Biomet Manufacturing, Llc | Patient-specific sacroiliac guides and associated methods |
US10456205B2 (en) | 2011-09-29 | 2019-10-29 | Biomet Manufacturing, Llc | Patient-specific femoroacetabular impingement instruments and methods |
US9386993B2 (en) | 2011-09-29 | 2016-07-12 | Biomet Manufacturing, Llc | Patient-specific femoroacetabular impingement instruments and methods |
US11406398B2 (en) | 2011-09-29 | 2022-08-09 | Biomet Manufacturing, Llc | Patient-specific femoroacetabular impingement instruments and methods |
US11298188B2 (en) | 2011-10-27 | 2022-04-12 | Biomet Manufacturing, Llc | Methods for patient-specific shoulder arthroplasty |
US10426549B2 (en) | 2011-10-27 | 2019-10-01 | Biomet Manufacturing, Llc | Methods for patient-specific shoulder arthroplasty |
US11602360B2 (en) | 2011-10-27 | 2023-03-14 | Biomet Manufacturing, Llc | Patient specific glenoid guide |
US9936962B2 (en) | 2011-10-27 | 2018-04-10 | Biomet Manufacturing, Llc | Patient specific glenoid guide |
US10842510B2 (en) | 2011-10-27 | 2020-11-24 | Biomet Manufacturing, Llc | Patient specific glenoid guide |
US9554910B2 (en) | 2011-10-27 | 2017-01-31 | Biomet Manufacturing, Llc | Patient-specific glenoid guide and implants |
US9451973B2 (en) | 2011-10-27 | 2016-09-27 | Biomet Manufacturing, Llc | Patient specific glenoid guide |
US9301812B2 (en) | 2011-10-27 | 2016-04-05 | Biomet Manufacturing, Llc | Methods for patient-specific shoulder arthroplasty |
US11419618B2 (en) | 2011-10-27 | 2022-08-23 | Biomet Manufacturing, Llc | Patient-specific glenoid guides |
US10426493B2 (en) | 2011-10-27 | 2019-10-01 | Biomet Manufacturing, Llc | Patient-specific glenoid guides |
US9351743B2 (en) | 2011-10-27 | 2016-05-31 | Biomet Manufacturing, Llc | Patient-specific glenoid guides |
US12089898B2 (en) | 2011-10-27 | 2024-09-17 | Biomet Manufacturing, Llc | Methods for patient-specific shoulder arthroplasty |
US9827106B2 (en) | 2012-02-02 | 2017-11-28 | Biomet Manufacturing, Llc | Implant with patient-specific porous structure |
US9237950B2 (en) | 2012-02-02 | 2016-01-19 | Biomet Manufacturing, Llc | Implant with patient-specific porous structure |
US9060788B2 (en) | 2012-12-11 | 2015-06-23 | Biomet Manufacturing, Llc | Patient-specific acetabular guide for anterior approach |
US9597201B2 (en) | 2012-12-11 | 2017-03-21 | Biomet Manufacturing, Llc | Patient-specific acetabular guide for anterior approach |
US9204977B2 (en) | 2012-12-11 | 2015-12-08 | Biomet Manufacturing, Llc | Patient-specific acetabular guide for anterior approach |
US10441298B2 (en) | 2013-03-11 | 2019-10-15 | Biomet Manufacturing, Llc | Patient-specific glenoid guide with a reusable guide holder |
US11617591B2 (en) | 2013-03-11 | 2023-04-04 | Biomet Manufacturing, Llc | Patient-specific glenoid guide with a reusable guide holder |
US9839438B2 (en) | 2013-03-11 | 2017-12-12 | Biomet Manufacturing, Llc | Patient-specific glenoid guide with a reusable guide holder |
US9579107B2 (en) | 2013-03-12 | 2017-02-28 | Biomet Manufacturing, Llc | Multi-point fit for patient specific guide |
US9700325B2 (en) | 2013-03-12 | 2017-07-11 | Biomet Manufacturing, Llc | Multi-point fit for patient specific guide |
US10426491B2 (en) | 2013-03-13 | 2019-10-01 | Biomet Manufacturing, Llc | Tangential fit of patient-specific guides |
US10376270B2 (en) | 2013-03-13 | 2019-08-13 | Biomet Manufacturing, Llc | Universal acetabular guide and associated hardware |
US9498233B2 (en) | 2013-03-13 | 2016-11-22 | Biomet Manufacturing, Llc. | Universal acetabular guide and associated hardware |
US9826981B2 (en) | 2013-03-13 | 2017-11-28 | Biomet Manufacturing, Llc | Tangential fit of patient-specific guides |
US11191549B2 (en) | 2013-03-13 | 2021-12-07 | Biomet Manufacturing, Llc | Tangential fit of patient-specific guides |
US9517145B2 (en) | 2013-03-15 | 2016-12-13 | Biomet Manufacturing, Llc | Guide alignment system and method |
US11179165B2 (en) | 2013-10-21 | 2021-11-23 | Biomet Manufacturing, Llc | Ligament guide registration |
US10282488B2 (en) | 2014-04-25 | 2019-05-07 | Biomet Manufacturing, Llc | HTO guide with optional guided ACL/PCL tunnels |
US9408616B2 (en) | 2014-05-12 | 2016-08-09 | Biomet Manufacturing, Llc | Humeral cut guide |
US9839436B2 (en) | 2014-06-03 | 2017-12-12 | Biomet Manufacturing, Llc | Patient-specific glenoid depth control |
US9561040B2 (en) | 2014-06-03 | 2017-02-07 | Biomet Manufacturing, Llc | Patient-specific glenoid depth control |
US9833245B2 (en) | 2014-09-29 | 2017-12-05 | Biomet Sports Medicine, Llc | Tibial tubercule osteotomy |
US9826994B2 (en) | 2014-09-29 | 2017-11-28 | Biomet Manufacturing, Llc | Adjustable glenoid pin insertion guide |
US10335162B2 (en) | 2014-09-29 | 2019-07-02 | Biomet Sports Medicine, Llc | Tibial tubercle osteotomy |
US11026699B2 (en) | 2014-09-29 | 2021-06-08 | Biomet Manufacturing, Llc | Tibial tubercule osteotomy |
US9926072B2 (en) | 2014-09-30 | 2018-03-27 | Safran Landing Systems Uk Ltd | Aerospace component and method for producing an aerospace component |
US9820868B2 (en) | 2015-03-30 | 2017-11-21 | Biomet Manufacturing, Llc | Method and apparatus for a pin apparatus |
US10568647B2 (en) | 2015-06-25 | 2020-02-25 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
US10226262B2 (en) | 2015-06-25 | 2019-03-12 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
US11801064B2 (en) | 2015-06-25 | 2023-10-31 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
US10925622B2 (en) | 2015-06-25 | 2021-02-23 | Biomet Manufacturing, Llc | Patient-specific humeral guide designs |
EP3120796A1 (en) | 2015-07-17 | 2017-01-25 | Mimedis AG | Method and system for the manufacture of an implant |
US10722310B2 (en) | 2017-03-13 | 2020-07-28 | Zimmer Biomet CMF and Thoracic, LLC | Virtual surgery planning system and method |
Also Published As
Publication number | Publication date |
---|---|
FR2979817B1 (en) | 2014-08-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2979817A1 (en) | Manufacturing bone prosthesis for filling gaps of all/part of bone of patient, comprises digitalizing patient using three-dimensional medical acquisition device by magnetic resonance, defining prosthesis, and manufacturing the prosthesis | |
EP3478222B1 (en) | Method for manufacture of a removable partial dental prosthesis by moulding with the aid of a mould formed by additive manufacture | |
Mohammed et al. | Advanced auricular prosthesis development by 3D modelling and multi-material printing | |
EP1006931B1 (en) | Method for producing a dental prosthesis | |
US8303746B2 (en) | Ocular prosthesis and fabrication method of same | |
FR2843537A1 (en) | Designing of bone implant for application to missing portion of bone body, e.g. skull, by generating three-dimensional data of bone based on pieces of bone tomographic data, and estimating shape of bone using generated data | |
JP2015516243A (en) | Implantable bone augmentation and method for manufacturing implantable bone augmentation | |
JPH11318962A (en) | Method for forming prosthetic surface | |
FR2750064A1 (en) | Three dimensional object forming method | |
EP3417828A1 (en) | Method of manufacturing an implant with titanium-based three-dimensional printing materia, implant with titanium-based three-dimensional printing material, method for designing an implant | |
US9242412B2 (en) | Method and apparatus for making partially coated products | |
FR3026937A1 (en) | SYNTHESIS BLOCK FOR FILLING A BONE FAULT AND METHOD FOR MANUFACTURING THE SAME | |
KR102020397B1 (en) | Dental implant abutment using additive manufacturing and manufacturing method thereof | |
FR2619707A1 (en) | PROSTHESIS IMPLANT SURROUNDED BY A POROUS SURFACE | |
WO2015082023A1 (en) | Method for manufacturing an implantable bone augment | |
TWI290126B (en) | The method of die forming | |
EP3815650A1 (en) | Method for manufacturing by 3d printing a socket device for orthopaedic apparatus such as a prosthesis | |
WO2022157439A1 (en) | Method for creating a 3d digital model of one or more aircraft elements in order to produce augmented reality images | |
EP1750190B1 (en) | Localised modification process for a stratified casting device and modification insert located in a stratum | |
BE1026129B1 (en) | Method of manufacturing prosthetic implants and kit of parts obtained by the method | |
EP3659557B1 (en) | Method of manufacturing a device for aiding in the fitting of a trapeziometacarpal prosthesis | |
EP1651143A2 (en) | Implant with improved homogeneity for plastic surgery and method for the production thereof | |
TWI679102B (en) | Three-dimensional printing manufacturing method of full denture | |
EP3257469A1 (en) | Method for producing a dental prosthesis implant pillar by additive manufacturing and spark machining and facility for implementing such a method | |
JP2004034298A (en) | Duplicate producing method, duplicate production entrustment service offering method, and data processing program |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 6 |
|
PLFP | Fee payment |
Year of fee payment: 7 |
|
PLFP | Fee payment |
Year of fee payment: 8 |
|
PLFP | Fee payment |
Year of fee payment: 9 |
|
PLFP | Fee payment |
Year of fee payment: 10 |
|
PLFP | Fee payment |
Year of fee payment: 11 |
|
ST | Notification of lapse |
Effective date: 20230505 |