FR2975907A1 - Composition, useful for podology, comprises antiperspirant agent, adhesion agent, sliding agent, colloidal silica, and optionally antibacterial agent and/or antifungal agent in conjunction or mixture with excipient or inert carrier - Google Patents

Abstract

Composition (I) comprises an antiperspirant agent, an adhesion agent, a sliding agent, colloidal silica, and optionally an antibacterial agent and/or antifungal agent in conjunction or mixture with an excipient or an inert carrier. An independent claim is included for a gaseous composition, which is prepared by adding an emulsifying solution containing an antioxidant to the (I) and conditioning in a gaseous atmosphere by an inert gas propellant. ACTIVITY : None given. MECHANISM OF ACTION : None given.

Description

The present invention relates to the field of the necessities of life and more particularly to the field of care of the feet and other ends of the body.

The invention more specifically relates to new compositions for the treatment or care of the feet to avoid excessive sweating, the development of unpleasant odors related to hypersudation or the occurrence of contamination by bacteria or pathogenic fungi frequently related maintaining an excessively moist organic environment. It specifically relates to novel podological, solid, liquid or gaseous compositions characterized in that they contain in combination an antiperspirant agent, an adhesion agent, a slip agent and colloidal silica mixed with an excipient or a Inert vehicle, non-toxic, perfectly tolerated by the skin.

In his prior patent 2,908,645 the Applicant has already described a composition ensuring the care and care of the feet without changing perspiration. These compositions contained as an essential ingredient an insoluble zinc derivative. The main characteristic of a zinc salt is to show a significant and lasting covering power. However, the skin tolerance of zinc salts has recently been questioned, and it is advisable to modulate the quantity of such an active principle.

The compositions according to the present invention serve another purpose. They are mainly aimed at reducing excessive foot sweating because hyperhidrosis is a factor of sores or irritation of the interdigital spaces or the soles of the feet. In addition, hyperhydrosis contributes to an easier development of fungal or bacterial infections. In order to avoid this type of painful or embarrassing manifestation, it seems necessary to make a new type of more active and more persistent podological compositions. The important element of this combination is the presence of colloidal silica and in particular of a particular quality of colloidal silica called Syloid which has absorbing and neutralizing properties. In particular, the Syloid product may be impregnated or soaked with lipophilic substance, which improves its spreading and its dehydration capacity. According to another modality of the presently preferred invention, the antiperspirant agent is a metal salt and especially an alum, a zirconium salt, a basic aluminum salt such as, for example, aluminum oxychloride or alkali metal carbonate. aluminum or sucralfate. According to another particular embodiment of the invention, the adhesion agent is an animal gum such as guar gum or Gellane gum or a marine gum such as laminarine, Furcellaria gum or Rhamnosoft gum (Solabia) or an eraser. plant such as gum arabic (or Senegal), acacia gum or gum sterculia.

According to another particular embodiment of the invention, the slip agent is essentially a polyacrylamide, an acrylic acid polymer, a metal stearate such as calcium stearate, magnesium stearate, talc or a bentonite clay, smectite, attapulgite. According to another embodiment of the invention, the combination according to the invention may be supplemented with an antibacterial agent or an antifungal agent such as zinc undecylenate which has both the anti-fungal properties of the undecylenic acid and those of zinc salts.

The compositions according to the invention may be in pulverulent form or in liquid form dispersed or dissolved in a fluid vehicle, semi-pasty or viscous, or in gasified form under pressure with a propellant such as carbon dioxide, a hydrofluorocarbon, Nitrogen or air. Preferably the compositions according to the invention are in the form of powdery compositions of great fluidity to be spread or blown on the feet, on the soles of the feet or in interdigital spaces. The podological compositions according to the invention may also be in the form of creams, emulsions, ointments, fluid gels to be easily applied in a sustainable manner, or film-forming preparations to be applied by brush. For this purpose, a fluid gel of acrylic acid or polyacrylamide polymer will be used as a vehicle so as to produce a gel whose viscosity does not exceed 1000 centipoise, and therefore easy to spread. Such a gel contains the active components, a gelling agent, an aromatizing agent, a neutralizing agent and / or a diluting agent. In particular the degree of viscosity can be regulated either by controlling the amount of polymer added to the composition, or by adjusting the pH of such a composition or by addition of the gel, mineral salts or complexing agent which reduce the viscosity . The podological compositions according to the invention find a particular use to reduce or eliminate odors released by shoes, socks or stockings after use. These compositions can be added additionally with antioxidants such as vitamin E or its derivatives, chitosan or its salts or lycopodium powder. Zinc undecylenate is a product of pharmaceutical quality as defined in the European Pharmacopoeia and the American Pharmacopoeia (USP). For the purposes of use as a deodorant product, the preparation is conditioned under a gas atmosphere by means of an inert propellant gas. In this way it is possible to distribute inside the shoes an effective and determined dose of active ingredients. Spraying is preferably carried out in the evening to allow the active ingredients of the powder time to diffuse and act. Then if necessary, we can proceed to brushing the inside of the shoes. It is still possible before use to introduce a new quantity of podological composition.

According to a particular embodiment of the invention, podological compositions according to the invention are intended to be administered or divided from 1 to 4 times per day.

The powders according to the invention can be colored or perfumed according to the desideratas of the user.

The invention also relates to a process for preparing podological compositions according to the invention which consists in progressively mixing the anhydrotic product and the adhesion agent, and then, after homogenization and / or sieving, to add the powder thus obtained from an agent. slip, zinc undecylenate and colloidal silica. Finally, the powder may be colored or scented with iron oxide, iron carbonates or vegetable dyes.

In podological compositions according to the invention, the content of the various constituents can undergo significant variations to improve the effectiveness of the preparations or the convenience of use. The antiperspirant content such as potassium alum or aluminum oxychloride may vary from 30 to 40% by weight and preferably from 32 to 36% with a preferred value of 35%. The content of the adhesive agent and in particular of guar gum or gum arabic can vary from 10 to 50% by weight with a preferred value of 35%.

The slip agent content may vary more widely, from 10 to 40% by weight with a preference in the case of talc or aluminum stearate of 20 to 30% and especially 25% by weight. The colloidal silica content can vary widely and is preferably from 0.4 to 5%. A colloidal silica content ranging from 0.5 to 4% is a preferred value.

In the case of the addition of antifungal agent and in particular of zinc undecylenate, the content of such an agent will be between 0.5 and 10% in the preparation. The antimycotic preparation may further be added with a softening agent such as starch glycerol at a dose ranging from 4 to 6 g and preferably 5 g%.

Such a composition and in particular the antifungal compositions according to the invention preferably have a consistency of fluid creams or powders which allow them to be divided into rigid or flexible tubes, in jars, in individual sachets or in individual capsules for a single use. . The following examples illustrate the invention without limiting it.

EXAMPLE I Foot Care Powder: Potassium Alum Guar Gum Talc Zinc Undecylenate Colloidal Silica The powder is divided into carefully closed 5 g spray bottles.

EXAMPLE II Foot Care Powder: - Potassium Alum 35 g 20 - Guar Gum 13.5 g - Talc 47 g - Colloidal Silica 0.5 g - Zinc Undecylenate 4.5 g For 100 g divided into powder flasks of 5 ml Example III Podological powder for the treatment of hyperhidrosis - Potassium alum 40 g - guar gum 3.1 g - Calcium stearate 48 g - Talc 47 g - Colloidal silica 2.6 g - Zinc undecylenate 2.5 g For 100 g of powder distributed in spray bottles. 35 g 35 g 25 g 4.0 g 1.0 g EXAMPLE IV Film-forming preparation for the protection of nails - Composition according to Example 1 10 g - Castor oil 10 to 15 g - Benzoin tincture 4 to 12 g - Urea 5 to 10 g - Grapefruit essential oil 1.5 g For a semi-fluid preparation to be applied with a brush on the nails. EXAMPLE V Antimycotic compositions - Podological powder according to Example 1 28 g - Starch glycerol 5g - Zinc undecylenate 4 g - Vinyl carbomer present in the form of Carbopol 934 in 0.4% solution 20 g - Essence of flowers 0 2 g - Benzoin tincture 0.8 g - Tiethanolamine 0.2 g - 0.1% Guar gum solution 40.0 g Example VI Preparation for the treatment of shoes: - Podological powder according to Example 1 after grinding 48 g - Vitamin E (acetate) 0.8 g - Chitosan Glutamate 3.0 - Mandarin essence 0.8 g - Polyacrylamide emulsifying solution 5.0 g - 90 ° Ethanol 50 g - Inert propellant gas ( nitrogen or compressed air) qs

This preparation is intended to remove odors in sports shoes, mountain boots or ski boots. It is applied every night. The preparation is packaged in drums with a check valve, for spraying spray, with a total volume of 200 ml or 150 ml as required.

Claims (9)

REVENDICATIONS1. Compositions for podiatry, pulverulent, fluid or gasified characterized in that they contain an antiperspirant agent, an adhesion agent, a slip agent and colloidal silica, and optionally an antibacterial and / or antifungal agent, in combination or in admixture with an excipient or an inert, non-toxic, skin-compatible carrier. 2. Compositions for podiatry according to claim 1, characterized in that the antiperspirant agent is an alum or an aluminum salt. 3. Compositions for podiatry according to claim 1 or claim 2, characterized in that the aluminum salt is aluminum oxychloride. 4. Compositions for podiatry according to claim 1 characterized in that the adhesion agent is a gum of plant origin, a gum of marine origin, or a gum of animal origin. 5. Compositions for podiatry according to claim 1, characterized in that the slip agent is a stearate or a clay of bentonite type, smectite, or attapulgite. 6. Compositions for podiatry according to claim 1, characterized in that the slip agent is a polyacrylamide or an acrylic acid polymer 7. Compositions for podiatry according to claim 1 wherein the colloidal silica is a particular quality called Syloid O. 8. Compositions for chiropody according to claim 1 and claim 2, characterized in that the antifungal agent is zinc undecylenate. 9. Gasified compositions for chiropody according to claim 1, characterized in that, in addition to the basic preparation according to claim 1, an emulsifying solution containing an antioxidant and are conditioned in a gaseous atmosphere by means of a gas inert propellant. 20 30