FR2955108B1 - Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson - Google Patents

Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson

Info

Publication number
FR2955108B1
FR2955108B1 FR1050098A FR1050098A FR2955108B1 FR 2955108 B1 FR2955108 B1 FR 2955108B1 FR 1050098 A FR1050098 A FR 1050098A FR 1050098 A FR1050098 A FR 1050098A FR 2955108 B1 FR2955108 B1 FR 2955108B1
Authority
FR
France
Prior art keywords
nurr
activators
parkinson
disease
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1050098A
Other languages
English (en)
Other versions
FR2955108A1 (fr
Inventor
Benaissa Boubia
Olivier Olivia Poupardin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inventiva SA
Original Assignee
Laboratories Fournier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Fournier SAS filed Critical Laboratories Fournier SAS
Priority to FR1050098A priority Critical patent/FR2955108B1/fr
Priority to PCT/FR2011/050022 priority patent/WO2011086307A1/fr
Publication of FR2955108A1 publication Critical patent/FR2955108A1/fr
Application granted granted Critical
Publication of FR2955108B1 publication Critical patent/FR2955108B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR1050098A 2010-01-08 2010-01-08 Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson Active FR2955108B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1050098A FR2955108B1 (fr) 2010-01-08 2010-01-08 Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson
PCT/FR2011/050022 WO2011086307A1 (fr) 2010-01-08 2011-01-07 Dérivés de pyrrolopyridine comme activateurs de nurr-1 utiles pour le traitement de la maladie de parkinson

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1050098A FR2955108B1 (fr) 2010-01-08 2010-01-08 Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson

Publications (2)

Publication Number Publication Date
FR2955108A1 FR2955108A1 (fr) 2011-07-15
FR2955108B1 true FR2955108B1 (fr) 2012-03-16

Family

ID=42144803

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1050098A Active FR2955108B1 (fr) 2010-01-08 2010-01-08 Utilisation de derives de pyrrolopyridine comme activateurs de nurr-1, pour le traitement de la maladie de parkinson

Country Status (2)

Country Link
FR (1) FR2955108B1 (fr)
WO (1) WO2011086307A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1648867T3 (da) 2003-07-17 2013-12-16 Plexxikon Inc Ppar-aktive forbindelser
FR2890072A1 (fr) * 2005-09-01 2007-03-02 Fournier S A Sa Lab Nouveaux composesde pyrrolopyridine
MX2009008324A (es) 2007-02-16 2009-10-20 Memory Pharm Corp Compuestos 6´-sustituidos que tienen afinidad con el receptor de 5-hidroxitriptamina-6.
FR2933609B1 (fr) * 2008-07-10 2010-08-27 Fournier Lab Sa Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson.

Also Published As

Publication number Publication date
WO2011086307A1 (fr) 2011-07-21
FR2955108A1 (fr) 2011-07-15

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