FR2944278B1 - Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines - Google Patents

Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines

Info

Publication number
FR2944278B1
FR2944278B1 FR0952322A FR0952322A FR2944278B1 FR 2944278 B1 FR2944278 B1 FR 2944278B1 FR 0952322 A FR0952322 A FR 0952322A FR 0952322 A FR0952322 A FR 0952322A FR 2944278 B1 FR2944278 B1 FR 2944278B1
Authority
FR
France
Prior art keywords
cyclodextrins
preparation
molecular complexes
retinoid agent
retinoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0952322A
Other languages
English (en)
Other versions
FR2944278A1 (fr
Inventor
Hubert Lochard
Bernard Freiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR0952322A priority Critical patent/FR2944278B1/fr
Priority to PCT/FR2010/050680 priority patent/WO2010116097A1/fr
Publication of FR2944278A1 publication Critical patent/FR2944278A1/fr
Application granted granted Critical
Publication of FR2944278B1 publication Critical patent/FR2944278B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FR0952322A 2009-04-09 2009-04-09 Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines Expired - Fee Related FR2944278B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0952322A FR2944278B1 (fr) 2009-04-09 2009-04-09 Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines
PCT/FR2010/050680 WO2010116097A1 (fr) 2009-04-09 2010-04-09 Procede de preparation de complexes moleculaires entre un agent retinoïde et des cyclodextrines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0952322A FR2944278B1 (fr) 2009-04-09 2009-04-09 Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines

Publications (2)

Publication Number Publication Date
FR2944278A1 FR2944278A1 (fr) 2010-10-15
FR2944278B1 true FR2944278B1 (fr) 2011-11-18

Family

ID=41393534

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0952322A Expired - Fee Related FR2944278B1 (fr) 2009-04-09 2009-04-09 Procede de preparation de complexes moleculaires entre un agent retinoide et des cyclodextrines

Country Status (2)

Country Link
FR (1) FR2944278B1 (fr)
WO (1) WO2010116097A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
JPH09176208A (ja) * 1995-12-22 1997-07-08 Wako Resource:Kk 包接化合物およびその製法
DE19847633C1 (de) * 1998-10-15 2000-03-02 Wacker Chemie Gmbh Verfahren zur Komplexierung von Retinol mit gamma-Cyclodextrin
FI20030426A (fi) * 2003-03-24 2004-09-25 Tomi Jaervinen Syklodekstriinikompleksit
FR2854079B1 (fr) * 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires

Also Published As

Publication number Publication date
WO2010116097A1 (fr) 2010-10-14
FR2944278A1 (fr) 2010-10-15

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