FR2937550B1 - Utilisation de la citrulline pour le traitement et la prevention du syndrome d'ischemie-reperfusion - Google Patents
Utilisation de la citrulline pour le traitement et la prevention du syndrome d'ischemie-reperfusionInfo
- Publication number
- FR2937550B1 FR2937550B1 FR0806004A FR0806004A FR2937550B1 FR 2937550 B1 FR2937550 B1 FR 2937550B1 FR 0806004 A FR0806004 A FR 0806004A FR 0806004 A FR0806004 A FR 0806004A FR 2937550 B1 FR2937550 B1 FR 2937550B1
- Authority
- FR
- France
- Prior art keywords
- citrulline
- ischemia
- prevention
- treatment
- reperfusion syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 title 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 title 1
- 229960002173 citrulline Drugs 0.000 title 1
- 235000013477 citrulline Nutrition 0.000 title 1
- 208000028867 ischemia Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0806004A FR2937550B1 (fr) | 2008-10-29 | 2008-10-29 | Utilisation de la citrulline pour le traitement et la prevention du syndrome d'ischemie-reperfusion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0806004A FR2937550B1 (fr) | 2008-10-29 | 2008-10-29 | Utilisation de la citrulline pour le traitement et la prevention du syndrome d'ischemie-reperfusion |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2937550A1 FR2937550A1 (fr) | 2010-04-30 |
FR2937550B1 true FR2937550B1 (fr) | 2010-12-10 |
Family
ID=40568554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0806004A Expired - Fee Related FR2937550B1 (fr) | 2008-10-29 | 2008-10-29 | Utilisation de la citrulline pour le traitement et la prevention du syndrome d'ischemie-reperfusion |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2937550B1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2970414B1 (fr) | 2011-01-14 | 2013-03-22 | Univ Paris Descartes | Action preventive de la citrulline sur le developpement spontane des tumeurs |
RU2611357C1 (ru) * | 2015-09-10 | 2017-02-21 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" министерства здравоохранения Российской Федерации | Способ профилактики реперфузионного синдрома при реконструктивных операциях на прецеребральных сосудах |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874471A (en) * | 1997-02-27 | 1999-02-23 | Waugh; William Howard | Orthomolecular medical use of L-citrulline for vasoprotection, relaxative smooth muscle tone and cell protection |
US20010056068A1 (en) * | 1998-03-04 | 2001-12-27 | Kristof Chwalisz | Method of treatment and prevention of nitric oxide deficiency-related disorders with citrulline and citrulline derivatives |
JP3843298B2 (ja) * | 2001-02-05 | 2006-11-08 | 国立大学法人 奈良先端科学技術大学院大学 | シトルリンを含有する活性酸素消去剤 |
-
2008
- 2008-10-29 FR FR0806004A patent/FR2937550B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2937550A1 (fr) | 2010-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TQ | Partial transmission of property | ||
PLFP | Fee payment |
Year of fee payment: 8 |
|
PLFP | Fee payment |
Year of fee payment: 9 |
|
ST | Notification of lapse |
Effective date: 20180629 |