FR2912133B1 - Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens - Google Patents

Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens

Info

Publication number
FR2912133B1
FR2912133B1 FR0700717A FR0700717A FR2912133B1 FR 2912133 B1 FR2912133 B1 FR 2912133B1 FR 0700717 A FR0700717 A FR 0700717A FR 0700717 A FR0700717 A FR 0700717A FR 2912133 B1 FR2912133 B1 FR 2912133B1
Authority
FR
France
Prior art keywords
antibacterians
novel
processes
preparation
indolic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0700717A
Other languages
English (en)
French (fr)
Other versions
FR2912133A1 (fr
Inventor
Jean-Noel Marie Leon Denis
Xavier Jean Georges Marie Guinchard
Nicole Jeanne Laffont
Luc Neuville
Yannick Vallee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0700717A priority Critical patent/FR2912133B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Joseph Fourier Grenoble 1 filed Critical Centre National de la Recherche Scientifique CNRS
Priority to CA2677146A priority patent/CA2677146C/fr
Priority to PCT/FR2008/000118 priority patent/WO2008110690A2/fr
Priority to EP08761826.0A priority patent/EP2121601B8/fr
Priority to AU2008224776A priority patent/AU2008224776B2/en
Priority to US12/525,503 priority patent/US8343964B2/en
Priority to RU2009132657/04A priority patent/RU2464261C2/ru
Priority to JP2009547728A priority patent/JP5368317B2/ja
Priority to CN2008800097669A priority patent/CN101652346B/zh
Publication of FR2912133A1 publication Critical patent/FR2912133A1/fr
Application granted granted Critical
Publication of FR2912133B1 publication Critical patent/FR2912133B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
FR0700717A 2007-02-01 2007-02-01 Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens Expired - Fee Related FR2912133B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR0700717A FR2912133B1 (fr) 2007-02-01 2007-02-01 Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
PCT/FR2008/000118 WO2008110690A2 (fr) 2007-02-01 2008-01-31 Nouveaux derives indoliques, leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
EP08761826.0A EP2121601B8 (fr) 2007-02-01 2008-01-31 Nouveaux derives indoliques, leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
AU2008224776A AU2008224776B2 (en) 2007-02-01 2008-01-31 Novel indole derivatives, methods for preparing same, and use thereof particularly as antibacterial agents
CA2677146A CA2677146C (fr) 2007-02-01 2008-01-31 Nouveaux derives indoliques, leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
US12/525,503 US8343964B2 (en) 2007-02-01 2008-01-31 Indolic derivatives, their preparation processes and their uses in particular as antibacterials
RU2009132657/04A RU2464261C2 (ru) 2007-02-01 2008-01-31 Новые индольные производные, способ их получения и их применение в качестве антибактериальных средств
JP2009547728A JP5368317B2 (ja) 2007-02-01 2008-01-31 新規なインドール誘導体それらの製造方法および特に抗菌剤としてのそれらの使用
CN2008800097669A CN101652346B (zh) 2007-02-01 2008-01-31 吲哚衍生物、其制备方法以及其用途，尤其是作为抗菌剂的用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0700717A FR2912133B1 (fr) 2007-02-01 2007-02-01 Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens

Publications (2)

Publication Number Publication Date
FR2912133A1 FR2912133A1 (fr) 2008-08-08
FR2912133B1 true FR2912133B1 (fr) 2009-04-24

Family

ID=38476052

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0700717A Expired - Fee Related FR2912133B1 (fr) 2007-02-01 2007-02-01 Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens

Country Status (9)

Country Link
US (1) US8343964B2 (https=)
EP (1) EP2121601B8 (https=)
JP (1) JP5368317B2 (https=)
CN (1) CN101652346B (https=)
AU (1) AU2008224776B2 (https=)
CA (1) CA2677146C (https=)
FR (1) FR2912133B1 (https=)
RU (1) RU2464261C2 (https=)
WO (1) WO2008110690A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011060976A1 (en) 2009-11-20 2011-05-26 Universite De Liege Tryptamine-derived compounds as antibacterial agents
FR2969150B1 (fr) * 2010-12-20 2013-07-26 Centre Nat Rech Scient Nouvelles molecules indoliques demontrant des activites antibacteriennes dans une variete de bacteries a gram-negatif et positif dont des bacteries multidrogues-resistantes
ES2464598T3 (es) 2011-07-22 2014-06-03 Université Joseph Fourier Nuevos derivados bis-indólicos, procedimiento para su preparación, y sus utilizaciones como fármaco
EP2548865B1 (en) 2011-07-22 2014-03-05 Université Joseph Fourier Novel bis-indolic derivatives, their uses in particular as antibacterials
EP2639220A1 (en) * 2012-03-15 2013-09-18 Omnia Molecular, S. L. Indole derivatives and their use as antibiotics
CN103664733B (zh) * 2013-12-10 2016-04-20 邯郸惠达化工有限公司 一种吲哚啉的制备方法
CN105669519B (zh) * 2016-01-04 2018-01-05 北方民族大学 吲哚类化合物、制备方法及其作为抗耐药菌药物的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492694A (en) * 1983-04-12 1985-01-08 Eli Lilly And Company Indolylglycyl cephalosporin derivatives
US5328902A (en) * 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
CA2444597A1 (en) * 2001-04-06 2002-10-06 Affinium Pharmaceuticals, Inc. Fab i inhibitors
DE602004016831D1 (de) * 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
DE10320453A1 (de) * 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin

Also Published As

Publication number Publication date
EP2121601A2 (fr) 2009-11-25
RU2464261C2 (ru) 2012-10-20
RU2009132657A (ru) 2011-03-10
EP2121601B1 (fr) 2016-06-15
AU2008224776A1 (en) 2008-09-18
US20100144726A1 (en) 2010-06-10
FR2912133A1 (fr) 2008-08-08
EP2121601B8 (fr) 2016-12-07
CA2677146C (fr) 2016-11-15
CA2677146A1 (fr) 2008-09-18
WO2008110690A3 (fr) 2009-03-19
US8343964B2 (en) 2013-01-01
CN101652346A (zh) 2010-02-17
CN101652346B (zh) 2013-10-30
AU2008224776B2 (en) 2012-09-06
JP5368317B2 (ja) 2013-12-18
JP2010517983A (ja) 2010-05-27
WO2008110690A2 (fr) 2008-09-18

Similar Documents

Publication Publication Date Title
FR20C1019I2 (fr) Promedicaments de composes de 2,4-pyrimidinediamine et leurs utilisations
ATE536355T1 (de) 3,3-spiroindolinionderivate als antikrebsmittel
MA28922B1 (fr) Nouveaux derives de phenylaminopyrimidine en tant qu'inhibiteurs de bcr-abl kinase
EP2067782A4 (en) Heterocyclic derivative, tetrahalogenated phenylenediamine, and process for its preparation
EP2401264A4 (en) PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR THEIR USE
BRPI0919331A2 (pt) derivados de pirazolo piridina, composições farmacêuticas e métodos associados
BRPI0916123A2 (pt) "composição de xampu concentrada"
EP2320737A4 (en) PYRAZOLO- [1,5-A] -PYRIDINE AS MARK HEMMER
BRPI0908050A2 (pt) Furo-e tieno[3,2-c]piridinas
EP2293685A4 (en) OILSAATPROTEIN CONCENTRATES AND ISOLATES, AND METHOD FOR THEIR PRODUCTION
FR2912133B1 (fr) Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
EP1923359A4 (en) FLUID AND MANUFACTURING METHOD THEREFOR
EP2802653A4 (en) COMPOSITIONS, PROCESS AND USE OF ALPHA-1-ANTITRYPHIN FUSION MOLECULES
BRPI0919248A2 (pt) derivados de 3-amino-indazol ou 3-amino-4,5,6,7-tetraidroindazol
WO2010004197A3 (fr) Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
PL2036892T3 (pl) Pochodne 1,2,4,5-tetrahydro-3H-benzazepin, sposób ich wytwarzania i zawierające je kompozycje farmaceutyczne
EP2320740A4 (en) PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING CONCENTRATIONS THEREOF OF LITTLE CONTAMINATION
FR2912744B1 (fr) Composes pyrrolo°2,3-b!pyridine,composes azaindoles utiles dans la synthese de ces composes pyrrolo°2,3-b!pyridine, leurs procedes de fabrication et leurs utilisations.
EP2888007A4 (en) NOVEL BENZIMIDAZOLTETRAHYDROFURANDERIVATE
DK2107055T3 (da) Dosmetinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
EP2470499A4 (en) NEW COLCHICINE DERIVATIVE AND METHOD AND USES THEREOF
BRPI0914503A2 (pt) "composição de shampoo concentrado"
BRPI0916363A2 (pt) derivados de 4,5-di-hidro-oxazol-2-ila
EP2386553A4 (en) BENZIMIDAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITIONS AND THEIR USE
SMT201400097B (it) Derivati di 2 piridin-2-il-pirazol-3(2H)-one, loropreparazione e loro applicazione in campo terapeu tico come attivatori di hif

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

ST Notification of lapse

Effective date: 20201006