FR2907011B1 - USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS - Google Patents

USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS

Info

Publication number
FR2907011B1
FR2907011B1 FR0609077A FR0609077A FR2907011B1 FR 2907011 B1 FR2907011 B1 FR 2907011B1 FR 0609077 A FR0609077 A FR 0609077A FR 0609077 A FR0609077 A FR 0609077A FR 2907011 B1 FR2907011 B1 FR 2907011B1
Authority
FR
France
Prior art keywords
denutrition
citrulline
treatment
conditions
denutrition conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0609077A
Other languages
French (fr)
Other versions
FR2907011A1 (en
Inventor
Christophe Moinard
Marion Jourdan
Stephane Walrand
Luc Cynober
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Assistance Publique Hopitaux de Paris APHP
Institut National de Recherche pour lAgriculture lAlimentation et lEnvironnement
Universite Paris Cite
Biocodex SAS
Original Assignee
Universite Paris 5 Rene Descartes
Biocodex SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0609077A priority Critical patent/FR2907011B1/en
Application filed by Universite Paris 5 Rene Descartes, Biocodex SAS filed Critical Universite Paris 5 Rene Descartes
Priority to US12/445,820 priority patent/US20100298437A1/en
Priority to PCT/FR2007/001407 priority patent/WO2008049984A2/en
Priority to CA002666538A priority patent/CA2666538A1/en
Priority to CNA2007800424825A priority patent/CN101605538A/en
Priority to JP2009532837A priority patent/JP2010506887A/en
Priority to EP07823453.1A priority patent/EP2081564B1/en
Publication of FR2907011A1 publication Critical patent/FR2907011A1/en
Priority to IL198182A priority patent/IL198182A0/en
Application granted granted Critical
Publication of FR2907011B1 publication Critical patent/FR2907011B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0609077A 2006-10-17 2006-10-17 USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS Expired - Fee Related FR2907011B1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0609077A FR2907011B1 (en) 2006-10-17 2006-10-17 USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS
PCT/FR2007/001407 WO2008049984A2 (en) 2006-10-17 2007-08-29 Use of citrulline for treating undernutrition conditions
CA002666538A CA2666538A1 (en) 2006-10-17 2007-08-29 Use of citrulline for treating undernutrition conditions
CNA2007800424825A CN101605538A (en) 2006-10-17 2007-08-29 Citrulline is used for the treatment of the purposes of undernutrition conditions
US12/445,820 US20100298437A1 (en) 2006-10-17 2007-08-29 Use of citrulline for treating undernutrition conditions
JP2009532837A JP2010506887A (en) 2006-10-17 2007-08-29 Use of citrulline for the treatment of undernourishment
EP07823453.1A EP2081564B1 (en) 2006-10-17 2007-08-29 Use of citrulline for treating undernutrition conditions
IL198182A IL198182A0 (en) 2006-10-17 2009-04-16 Use of citrulline for treating undernutrition conditions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0609077A FR2907011B1 (en) 2006-10-17 2006-10-17 USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS

Publications (2)

Publication Number Publication Date
FR2907011A1 FR2907011A1 (en) 2008-04-18
FR2907011B1 true FR2907011B1 (en) 2010-05-14

Family

ID=37888135

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0609077A Expired - Fee Related FR2907011B1 (en) 2006-10-17 2006-10-17 USE OF CITRULLINE FOR THE TREATMENT OF DENUTRITION CONDITIONS

Country Status (8)

Country Link
US (1) US20100298437A1 (en)
EP (1) EP2081564B1 (en)
JP (1) JP2010506887A (en)
CN (1) CN101605538A (en)
CA (1) CA2666538A1 (en)
FR (1) FR2907011B1 (en)
IL (1) IL198182A0 (en)
WO (1) WO2008049984A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2913885B1 (en) * 2007-03-22 2012-07-20 Univ Paris Descartes USE OF CITRULLINE FOR THE TREATMENT OF PATHOLOGIES ASSOCIATED WITH INCREASED CARBONYLATION OF PROTEINS
DE102007016715A1 (en) * 2007-04-04 2008-10-09 Evonik Degussa Gmbh Nutritional supplement containing alpha-keto acids
WO2012005568A1 (en) 2010-07-07 2012-01-12 N.V. Nutricia Nutritional composition for the stimulation of muscle protein synthesis
FR2970414B1 (en) 2011-01-14 2013-03-22 Univ Paris Descartes PREVENTIVE ACTION OF CITRULLINE ON THE SPONTANEOUS DEVELOPMENT OF TUMORS
ES2636479T3 (en) 2013-06-10 2017-10-05 N.V. Nutricia Muscle preservation in the overweight or obese adult during a weight loss program
FR3009963B1 (en) 2013-09-03 2017-03-03 Biolis COMPOSITION FOR CONTROLLING LOCOMOTION DISORDERS
PL2875736T3 (en) 2013-11-26 2017-02-28 Citrage N-Carbamoylputrescine to enhance muscle protein synthesis
JPWO2015137387A1 (en) * 2014-03-11 2017-04-06 協和発酵バイオ株式会社 Muscle enhancer
CN104263550A (en) * 2014-09-11 2015-01-07 滁州斯迈特复合材料有限公司 Makeup solution glass bottle detergent
WO2017038991A1 (en) * 2015-09-04 2017-03-09 国立大学法人 筑波大学 Composition for muscle building and method for building muscle
KR102396603B1 (en) 2015-09-16 2022-05-11 원광대학교산학협력단 Composition for improving liver function comprising citrulline as an active ingredient
WO2017075289A1 (en) 2015-10-27 2017-05-04 Cytozyme Animal Nutrition, Inc. Animal nutrition compositions and related methods
US10674746B2 (en) 2015-10-27 2020-06-09 Cytozyme Animal Nutrition, Inc. Animal nutrition compositions and related methods
EP3773013A1 (en) 2018-03-27 2021-02-17 N.V. Nutricia Insulin control in overweight or obese adult during life time intervention

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6306M (en) * 1966-12-15 1968-09-16
FR6305M (en) * 1966-12-15 1968-09-16
FR6304M (en) * 1966-12-15 1968-09-16
US4988724A (en) * 1988-12-09 1991-01-29 Board Of Regents, The University Of Texas System Methods and improved formulations for the determination and treatment of malignant disease in patients
US5189025A (en) * 1988-12-09 1993-02-23 Board Of Regenets, The University Of Texas System Methods for the treatment of malignant disease in patients using citrulline containing amino acid solutions
FR2691359B1 (en) * 1992-05-20 1995-06-23 Krempf Michel NEW THERAPEUTIC APPLICATION OF 1-CITRULLINE MALATE.
US20010056068A1 (en) * 1998-03-04 2001-12-27 Kristof Chwalisz Method of treatment and prevention of nitric oxide deficiency-related disorders with citrulline and citrulline derivatives
US9486429B2 (en) * 1999-06-01 2016-11-08 Vanderbilt University Therapeutic methods employing nitric oxide precursors
FR2857262B1 (en) * 2003-07-08 2007-10-05 Biocodex Lab USE OF CITRULLINE IN THE CONTEXT OF INTESTINAL FAILURE

Also Published As

Publication number Publication date
JP2010506887A (en) 2010-03-04
EP2081564B1 (en) 2014-01-01
US20100298437A1 (en) 2010-11-25
WO2008049984A2 (en) 2008-05-02
EP2081564A2 (en) 2009-07-29
CA2666538A1 (en) 2008-05-02
WO2008049984A3 (en) 2008-06-19
CN101605538A (en) 2009-12-16
IL198182A0 (en) 2009-12-24
FR2907011A1 (en) 2008-04-18

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Owner name: BIOCODEX, FR

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Owner name: ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, FR

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Owner name: UNIVERSITE PARIS DESCARTES, FR

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