FR2848112A1 - Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations - Google Patents
Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations Download PDFInfo
- Publication number
- FR2848112A1 FR2848112A1 FR0215586A FR0215586A FR2848112A1 FR 2848112 A1 FR2848112 A1 FR 2848112A1 FR 0215586 A FR0215586 A FR 0215586A FR 0215586 A FR0215586 A FR 0215586A FR 2848112 A1 FR2848112 A1 FR 2848112A1
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical composition
- acid
- composition according
- percentages
- estradiol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (23)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0215586A FR2848112B1 (fr) | 2002-12-10 | 2002-12-10 | Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations |
US10/393,077 US20040110732A1 (en) | 2002-12-10 | 2003-03-20 | Pharmaceutical composition for transdermal or transmucosal administration comprising at least one progestin and/or at least one oestrogen, process for preparing it and uses thereof |
PCT/FR2003/003663 WO2004054544A1 (fr) | 2002-12-10 | 2003-12-10 | Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant un progestatif et un oestrogene, son procede de preparation et ses utilisations |
AU2003296810A AU2003296810A1 (en) | 2002-12-10 | 2003-12-10 | Pharmaceutical composition for transdermal or transmucous administration comprising a progestin or an estrogen, method for preparing same and uses thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0215586A FR2848112B1 (fr) | 2002-12-10 | 2002-12-10 | Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2848112A1 true FR2848112A1 (fr) | 2004-06-11 |
FR2848112B1 FR2848112B1 (fr) | 2007-02-16 |
Family
ID=32320148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0215586A Expired - Lifetime FR2848112B1 (fr) | 2002-12-10 | 2002-12-10 | Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations |
Country Status (2)
Country | Link |
---|---|
US (1) | US20040110732A1 (fr) |
FR (1) | FR2848112B1 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US20030139384A1 (en) * | 2000-08-30 | 2003-07-24 | Dudley Robert E. | Method for treating erectile dysfunction and increasing libido in men |
AR036970A1 (es) * | 2002-03-15 | 2004-10-20 | Unimed Pharmaceuticals Inc | Composicion farmaceutica androgenica y metodo para el tratamiento de la depresion |
FR2851470B1 (fr) * | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
US10016442B2 (en) * | 2005-06-16 | 2018-07-10 | Allergan Pharmaceuticals International Limited | Estrogen compositions for vaginal administration |
CN101232869B (zh) * | 2005-06-16 | 2016-03-02 | 沃纳奇尔科特有限责任公司 | 局部给药的凝胶组合物 |
CA2612415A1 (fr) * | 2005-06-16 | 2006-12-28 | Warner Chilcott Company, Inc. | Compositions d'oestrogene pour administration vaginale |
CN101287470B (zh) | 2005-10-12 | 2012-10-17 | 优尼麦德药物股份有限公司 | 改良的睾酮凝胶及使用方法 |
EP2147674A1 (fr) * | 2008-07-24 | 2010-01-27 | Besins Healthcare | Compositions pharmaceutiques transdermiques comprenant du danazol |
US10080760B2 (en) | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
US9271991B2 (en) | 2010-10-27 | 2016-03-01 | Dignity Health | Trimegestone (TMG) for treatment of preterm birth |
BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然の併用ホルモン補充療法剤及び療法 |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
EP3435977A4 (fr) | 2016-04-01 | 2019-10-16 | Therapeuticsmd, Inc. | Composition pharmaceutique d'hormone stéroïde |
ES2966159T3 (es) * | 2016-08-22 | 2024-04-18 | Or Genix Therapeutics Inc | Ligandos selectivos del receptor beta de estrógeno |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4906169A (en) * | 1986-12-29 | 1990-03-06 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
EP0364211A1 (fr) * | 1988-10-11 | 1990-04-18 | Shire Holdings Ltd. | Préparation pharmaceutique percutanée |
WO1994004157A1 (fr) * | 1992-08-21 | 1994-03-03 | Schering Aktiengesellschaft | Agent d'application transdermique contenant du 3-ceto-desogestrel |
EP0737477A1 (fr) * | 1993-12-27 | 1996-10-16 | Akzo Nobel N.V. | Preparation pour absorption par voie percutanee |
WO1998032465A1 (fr) * | 1997-01-27 | 1998-07-30 | Lg Chemical Limited | Composition pour l'administration transdermique de medicaments steroides |
RU2122396C1 (ru) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Биологически-активная добавка в косметические изделия |
WO2002022132A2 (fr) * | 2000-09-15 | 2002-03-21 | Laboratoire Theramex | Nouvelles compositions estro-progestatives topiques a effet systemique |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0370220B1 (fr) * | 1988-10-27 | 1996-01-10 | Schering Aktiengesellschaft | Composition de Gestoden à application transdermique |
IT1283102B1 (it) * | 1996-06-06 | 1998-04-07 | Permatec Nv | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
-
2002
- 2002-12-10 FR FR0215586A patent/FR2848112B1/fr not_active Expired - Lifetime
-
2003
- 2003-03-20 US US10/393,077 patent/US20040110732A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4906169A (en) * | 1986-12-29 | 1990-03-06 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
EP0364211A1 (fr) * | 1988-10-11 | 1990-04-18 | Shire Holdings Ltd. | Préparation pharmaceutique percutanée |
WO1994004157A1 (fr) * | 1992-08-21 | 1994-03-03 | Schering Aktiengesellschaft | Agent d'application transdermique contenant du 3-ceto-desogestrel |
EP0737477A1 (fr) * | 1993-12-27 | 1996-10-16 | Akzo Nobel N.V. | Preparation pour absorption par voie percutanee |
RU2122396C1 (ru) * | 1996-07-12 | 1998-11-27 | Валентина Александровна Андрюшина | Биологически-активная добавка в косметические изделия |
WO1998032465A1 (fr) * | 1997-01-27 | 1998-07-30 | Lg Chemical Limited | Composition pour l'administration transdermique de medicaments steroides |
WO2002022132A2 (fr) * | 2000-09-15 | 2002-03-21 | Laboratoire Theramex | Nouvelles compositions estro-progestatives topiques a effet systemique |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Derwent World Patents Index; AN 2000-170047, XP002240585 * |
Also Published As
Publication number | Publication date |
---|---|
US20040110732A1 (en) | 2004-06-10 |
FR2848112B1 (fr) | 2007-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CA | Change of address |
Effective date: 20111123 |
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CD | Change of name or company name |
Owner name: BESINS HEALTHCARE LUXEMBOURG SARL, LU Effective date: 20111123 |
|
TP | Transmission of property |
Owner name: BESINS HEALTHCARE LUXEMBOURG SARL, LU Effective date: 20111123 |
|
CA | Change of address |
Effective date: 20150917 |
|
PLFP | Fee payment |
Year of fee payment: 14 |
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PLFP | Fee payment |
Year of fee payment: 15 |
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PLFP | Fee payment |
Year of fee payment: 16 |
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PLFP | Fee payment |
Year of fee payment: 17 |
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PLFP | Fee payment |
Year of fee payment: 18 |
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PLFP | Fee payment |
Year of fee payment: 19 |
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PLFP | Fee payment |
Year of fee payment: 20 |