FR2842737B1 - Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives - Google Patents

Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives

Info

Publication number
FR2842737B1
FR2842737B1 FR0209436A FR0209436A FR2842737B1 FR 2842737 B1 FR2842737 B1 FR 2842737B1 FR 0209436 A FR0209436 A FR 0209436A FR 0209436 A FR0209436 A FR 0209436A FR 2842737 B1 FR2842737 B1 FR 2842737B1
Authority
FR
France
Prior art keywords
hyaluronane
derivatives
active materials
particles coated
biological vectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0209436A
Other languages
English (en)
Other versions
FR2842737A1 (fr
Inventor
Edith Dellacherie
Michele Leonard
Ruxandra Gref
Patrick Netter
Elisabeth Payan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite de Lorraine
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0209436A priority Critical patent/FR2842737B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to US10/522,333 priority patent/US20050271730A1/en
Priority to CA2493470A priority patent/CA2493470C/fr
Priority to PCT/FR2003/002299 priority patent/WO2004014347A1/fr
Priority to AU2003278209A priority patent/AU2003278209A1/en
Priority to EP03769524A priority patent/EP1524970A1/fr
Publication of FR2842737A1 publication Critical patent/FR2842737A1/fr
Application granted granted Critical
Publication of FR2842737B1 publication Critical patent/FR2842737B1/fr
Priority to US13/137,283 priority patent/US20120003320A1/en
Priority to US13/675,734 priority patent/US20130071480A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0209436A 2002-07-25 2002-07-25 Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives Expired - Fee Related FR2842737B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0209436A FR2842737B1 (fr) 2002-07-25 2002-07-25 Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives
CA2493470A CA2493470C (fr) 2002-07-25 2003-07-21 Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives
PCT/FR2003/002299 WO2004014347A1 (fr) 2002-07-25 2003-07-21 Centre national de la recherche scientifique
AU2003278209A AU2003278209A1 (en) 2002-07-25 2003-07-21 Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances
US10/522,333 US20050271730A1 (en) 2002-07-25 2003-07-21 Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances
EP03769524A EP1524970A1 (fr) 2002-07-25 2003-07-21 Particules enrobees avec de la hyluronane ou un de ces derives et son utilisation comme vecteurs biologiques pour les principes actifs
US13/137,283 US20120003320A1 (en) 2002-07-25 2011-08-03 Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances
US13/675,734 US20130071480A1 (en) 2002-07-25 2012-11-13 Particles which are surface coated with hyaluronan or one of the derivatives thereof and the use of same as biological vectors for active substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0209436A FR2842737B1 (fr) 2002-07-25 2002-07-25 Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives

Publications (2)

Publication Number Publication Date
FR2842737A1 FR2842737A1 (fr) 2004-01-30
FR2842737B1 true FR2842737B1 (fr) 2006-01-27

Family

ID=30011470

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0209436A Expired - Fee Related FR2842737B1 (fr) 2002-07-25 2002-07-25 Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives

Country Status (6)

Country Link
US (3) US20050271730A1 (fr)
EP (1) EP1524970A1 (fr)
AU (1) AU2003278209A1 (fr)
CA (1) CA2493470C (fr)
FR (1) FR2842737B1 (fr)
WO (1) WO2004014347A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2924606B1 (fr) * 2007-12-10 2010-08-13 Jean Noel Thorel Composition a base d'acide hyaluronique pour l'hydratation de la peau.
WO2009155059A2 (fr) * 2008-05-28 2009-12-23 Trustees Of Tufts College Composition de polysaccharide et procédés permettant d'isoler le polysaccharide polyélectrolytique cationique de stabilisation d'émulsion
WO2010011857A2 (fr) * 2008-07-23 2010-01-28 The Johns Hopkins University Administration parentérale d'une glucosamine
US20160030349A1 (en) * 2014-08-01 2016-02-04 Boehringer Ingelheim Vetmedica Gmbh Nanoparticles, methods of preparation, and uses thereof
CA3074449A1 (fr) * 2017-09-05 2019-03-14 Excel Med, Llc Composition d'heparine pour le traitement de l'ischemie
WO2020129028A1 (fr) * 2018-12-21 2020-06-25 Nestlé Skin Health S.A. Compositions d'hydrogel encapsulant des particules solides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
GB8601100D0 (en) * 1986-01-17 1986-02-19 Cosmas Damian Ltd Drug delivery system
US5736372A (en) * 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
WO1992016191A1 (fr) * 1991-03-25 1992-10-01 Fujisawa Pharmaceutical Co., Ltd. Preparation pharmaceutique a action prolongee
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
ATE252894T1 (de) * 1995-01-05 2003-11-15 Univ Michigan Oberflächen-modifizierte nanopartikel und verfahren für ihre herstellung und verwendung
KR100201352B1 (ko) * 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US6193951B1 (en) * 1997-04-30 2001-02-27 Point Biomedical Corporation Microparticles useful as ultrasonic contrast agents
FR2809112B1 (fr) * 2000-05-16 2004-05-07 Centre Nat Rech Scient Materiaux a base de polymeres biodegradables et son procede de preparation
FR2842106B1 (fr) * 2002-07-11 2006-07-14 Centre Nat Rech Scient Dispersions aqueuses de particules nanometriques ou micrometriques pour l'encapsulation de composes chimiques

Also Published As

Publication number Publication date
WO2004014347A1 (fr) 2004-02-19
CA2493470C (fr) 2012-05-22
AU2003278209A1 (en) 2004-02-25
US20050271730A1 (en) 2005-12-08
US20120003320A1 (en) 2012-01-05
CA2493470A1 (fr) 2004-02-19
US20130071480A1 (en) 2013-03-21
EP1524970A1 (fr) 2005-04-27
FR2842737A1 (fr) 2004-01-30

Similar Documents

Publication Publication Date Title
AU2003265859A8 (en) Assays and compositions for identifying agents that modulate the activity of deubiquitinating agents
FR2791580B1 (fr) Procede pour l'enrobage de particules
ATE253361T1 (de) Mittel zur gesteuerten freisetzung von paroxetin
FR2830848B1 (fr) Dispositif d'application d'un produit notamment cosmetique avec un organe d'application amovible
DE60038478D1 (de) Vorrichtung zur Injektion von Kontrastmitteln
DE59602698D1 (de) Auftragskopf zur dosierten Abgabe von strömenden Medien
PT864559E (pt) Compostos amino substituidos e sua utilizacao como substancias activas analgesicas
FR13C0044I2 (fr) Utilisation de dihydroimidazolones pour le traitement de l'epilepsie canine
ID26648A (id) Bahan-bahan partikulat untuk penggunaan dalam komposisi-komposisi sediaan pembersih gigi
FR2845000B1 (fr) Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute
FR2842737B1 (fr) Particules revetues en surface de hyaluronane ou d'un de ses derives et leur utilisation a titre de vecteurs biologiques pour des matieres actives
ITMI981903A0 (it) Materiali immonologici e metodi per la rivelazione di diidropirimidina deidrognasi
ITPD20040010U1 (it) Dispositivo per l'applicazione di liquidi con piatti di spruzzatura rotanti
FR2802812B1 (fr) Utilisation de residus issus de la fabrication du vin pour la fabrication de preparations cosmetiques et/ou pharmaceutiques.
DE60001725D1 (de) Verwendung des saredutant und seiner pharmazeutisch akzeptablen salze zur behandlung von schwere depression
FR2765480B1 (fr) Utilisation pour le revetement des matieres keratiniques d'un materiau polymerique hybride ; compositions cosmetiques ou dermatologiques
FR2835823B1 (fr) Procede de preparation d'un produit a base de phosphate de thorium et/ou d'actinides
MA27184A1 (fr) Dosage d'anticorps anti-ingap
FR2804601B1 (fr) Dispositif d'application de principes actifs utilisables dans le domaine pharmaceutique ou cosmetique
ATE300531T1 (de) Isonipecotamide zur behandlung von integrin vermittelten störungen
AU2001280540A1 (en) Inhibitors of plant peptide deformylase for use as broad-spectrum herbicides and methods for identifying the same
IT1307255B1 (it) Dispositivo per l'immagazzinamento e la distribuzione di farmacicontenuti in contenitori.
DE69824497D1 (de) Vorrichtung zur Regulierung der Bewegung von Feststoffpartikeln in Wirbelschichten
ID27325A (id) Alat penampungan dan penyaluran cairan
FR2837177B1 (fr) Ensemble pour le conditionnement et la distribution d'un produit, notamment sous forme d'un echantillon

Legal Events

Date Code Title Description
TQ Partial transmission of property

Owner name: UNIVERSITE DE LORRAINE, FR

Effective date: 20130204

Owner name: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (, FR

Effective date: 20130204

ST Notification of lapse

Effective date: 20160331