FR2832312B1 - Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques - Google Patents

Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques

Info

Publication number
FR2832312B1
FR2832312B1 FR0115046A FR0115046A FR2832312B1 FR 2832312 B1 FR2832312 B1 FR 2832312B1 FR 0115046 A FR0115046 A FR 0115046A FR 0115046 A FR0115046 A FR 0115046A FR 2832312 B1 FR2832312 B1 FR 2832312B1
Authority
FR
France
Prior art keywords
microparticles
preparation
pharmaceutical compositions
obtained according
toxic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0115046A
Other languages
English (en)
Other versions
FR2832312A1 (fr
Inventor
Pouessel Anne Aubert
Julienne Marie Claire Venier
Jean Pierre Benoit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to FR0115046A priority Critical patent/FR2832312B1/fr
Priority to AU2002350884A priority patent/AU2002350884A1/en
Priority to PCT/FR2002/003817 priority patent/WO2003043605A1/fr
Publication of FR2832312A1 publication Critical patent/FR2832312A1/fr
Application granted granted Critical
Publication of FR2832312B1 publication Critical patent/FR2832312B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
FR0115046A 2001-11-21 2001-11-21 Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques Expired - Fee Related FR2832312B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0115046A FR2832312B1 (fr) 2001-11-21 2001-11-21 Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques
AU2002350884A AU2002350884A1 (en) 2001-11-21 2002-11-07 Method for preparing microparticles free of toxic solvent, resulting microparticles and pharmaceutical compositions
PCT/FR2002/003817 WO2003043605A1 (fr) 2001-11-21 2002-11-07 Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0115046A FR2832312B1 (fr) 2001-11-21 2001-11-21 Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
FR2832312A1 FR2832312A1 (fr) 2003-05-23
FR2832312B1 true FR2832312B1 (fr) 2004-01-16

Family

ID=8869622

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0115046A Expired - Fee Related FR2832312B1 (fr) 2001-11-21 2001-11-21 Procede de preparation de microparticules sans solvant toxique, microparticules obtenues selon ce procede, utilisations et compositions pharmaceutiques

Country Status (3)

Country Link
AU (1) AU2002350884A1 (fr)
FR (1) FR2832312B1 (fr)
WO (1) WO2003043605A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE527505C2 (sv) * 2003-06-10 2006-03-28 Anna Imberg Komposita material och partiklar

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS528795B2 (fr) * 1971-12-30 1977-03-11
JP2670680B2 (ja) * 1988-02-24 1997-10-29 株式会社ビーエムジー 生理活性物質含有ポリ乳酸系微小球およびその製造法
KR0162872B1 (ko) * 1996-04-01 1998-12-01 김은영 용매추출법을 이용한 생분해성 고분자 미립구의 개선된 제조방법 및 이를 이용한 국소염증 질환 치료용 미립구의 제조방법
GB9805417D0 (en) * 1998-03-14 1998-05-06 Core Technologies Limited Production of microparticles
US6291013B1 (en) * 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles
FR2797784B1 (fr) * 1999-08-27 2001-11-30 Mainelab Procede d'encapsulation de matieres actives par coacervation de polymeres en solvant organique non-chlore

Also Published As

Publication number Publication date
AU2002350884A1 (en) 2003-06-10
WO2003043605A1 (fr) 2003-05-30
FR2832312A1 (fr) 2003-05-23

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