FR2820135B1 - Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation - Google Patents

Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation

Info

Publication number
FR2820135B1
FR2820135B1 FR0101165A FR0101165A FR2820135B1 FR 2820135 B1 FR2820135 B1 FR 2820135B1 FR 0101165 A FR0101165 A FR 0101165A FR 0101165 A FR0101165 A FR 0101165A FR 2820135 B1 FR2820135 B1 FR 2820135B1
Authority
FR
France
Prior art keywords
preparation
pyrimidine acyclonucleoside
derivatives
acyclonucleoside derivatives
pyrimidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0101165A
Other languages
English (en)
Other versions
FR2820135A1 (fr
Inventor
Jean Mj Tronchet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Geneve
Original Assignee
Universite de Geneve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0101165A priority Critical patent/FR2820135B1/fr
Application filed by Universite de Geneve filed Critical Universite de Geneve
Priority to US10/470,564 priority patent/US6911450B1/en
Priority to DE60221794T priority patent/DE60221794D1/de
Priority to CNB02805458XA priority patent/CN1231472C/zh
Priority to EP02703583A priority patent/EP1355887B1/fr
Priority to CA002436958A priority patent/CA2436958A1/fr
Priority to AT02703583T priority patent/ATE370127T1/de
Priority to PCT/EP2002/000839 priority patent/WO2002060880A1/fr
Publication of FR2820135A1 publication Critical patent/FR2820135A1/fr
Application granted granted Critical
Publication of FR2820135B1 publication Critical patent/FR2820135B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0101165A 2001-01-29 2001-01-29 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation Expired - Fee Related FR2820135B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0101165A FR2820135B1 (fr) 2001-01-29 2001-01-29 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation
DE60221794T DE60221794D1 (de) 2001-01-29 2002-01-25 Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung
CNB02805458XA CN1231472C (zh) 2001-01-29 2002-01-25 嘧啶无环核苷衍生物、其制备方法及其用途
EP02703583A EP1355887B1 (fr) 2001-01-29 2002-01-25 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation
US10/470,564 US6911450B1 (en) 2001-01-29 2002-01-25 Pyrimidine acyclonucleoside derivatives, preparation method and use thereof
CA002436958A CA2436958A1 (fr) 2001-01-29 2002-01-25 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation
AT02703583T ATE370127T1 (de) 2001-01-29 2002-01-25 Pyrimidinische azyklonukleoside, verfahren zur ihrer herstellung und ihre verwendung
PCT/EP2002/000839 WO2002060880A1 (fr) 2001-01-29 2002-01-25 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0101165A FR2820135B1 (fr) 2001-01-29 2001-01-29 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation

Publications (2)

Publication Number Publication Date
FR2820135A1 FR2820135A1 (fr) 2002-08-02
FR2820135B1 true FR2820135B1 (fr) 2005-01-14

Family

ID=8859349

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0101165A Expired - Fee Related FR2820135B1 (fr) 2001-01-29 2001-01-29 Derives d'acyclonucleosides pyrimidiniques, leur procede de preparation et leur utilisation

Country Status (1)

Country Link
FR (1) FR2820135B1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU205917B (en) * 1989-09-29 1992-07-28 Mitsubishi Chem Ind Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components
EP0631783A1 (fr) * 1993-06-03 1995-01-04 Mitsubishi Chemical Corporation Combinaisons antivirales de 2',3'-didéoxy-ribonucléosides avec des dérivés 5-substitués du 6-benzyl-1-éthoxyméthyl-uracile

Also Published As

Publication number Publication date
FR2820135A1 (fr) 2002-08-02

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Legal Events

Date Code Title Description
TQ Partial transmission of property
ST Notification of lapse

Effective date: 20081029