FR2798556B1 - Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux - Google Patents

Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux

Info

Publication number
FR2798556B1
FR2798556B1 FR9911678A FR9911678A FR2798556B1 FR 2798556 B1 FR2798556 B1 FR 2798556B1 FR 9911678 A FR9911678 A FR 9911678A FR 9911678 A FR9911678 A FR 9911678A FR 2798556 B1 FR2798556 B1 FR 2798556B1
Authority
FR
France
Prior art keywords
mitochondrial
malfunctions
alzheimer
disease
animal model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9911678A
Other languages
English (en)
Other versions
FR2798556A1 (fr
Inventor
Mrabet Saliha Moussaoui
Bregeon Veronique Blanchard
Assunta Imperato
Bruno Bonici
Gunter Tremp
Christian Czech
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR9911678A priority Critical patent/FR2798556B1/fr
Priority to EP00962636A priority patent/EP1235482A1/fr
Priority to PCT/FR2000/002540 priority patent/WO2001020977A1/fr
Priority to JP2001524418A priority patent/JP2003509071A/ja
Priority to CA002384865A priority patent/CA2384865A1/fr
Priority to AU74294/00A priority patent/AU7429400A/en
Publication of FR2798556A1 publication Critical patent/FR2798556A1/fr
Application granted granted Critical
Publication of FR2798556B1 publication Critical patent/FR2798556B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9911678A 1999-09-17 1999-09-17 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux Expired - Fee Related FR2798556B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9911678A FR2798556B1 (fr) 1999-09-17 1999-09-17 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux
EP00962636A EP1235482A1 (fr) 1999-09-17 2000-09-14 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux
PCT/FR2000/002540 WO2001020977A1 (fr) 1999-09-17 2000-09-14 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux
JP2001524418A JP2003509071A (ja) 1999-09-17 2000-09-14 アミロイド斑およびミトコンドリア機能障害を示すアルツハイマー病の新規の動物モデル
CA002384865A CA2384865A1 (fr) 1999-09-17 2000-09-14 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux
AU74294/00A AU7429400A (en) 1999-09-17 2000-09-14 Novel animal model of alzheimer disease with amyloid plaques and mitochondrial dysfunctions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9911678A FR2798556B1 (fr) 1999-09-17 1999-09-17 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux

Publications (2)

Publication Number Publication Date
FR2798556A1 FR2798556A1 (fr) 2001-03-23
FR2798556B1 true FR2798556B1 (fr) 2004-02-27

Family

ID=9549989

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9911678A Expired - Fee Related FR2798556B1 (fr) 1999-09-17 1999-09-17 Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux

Country Status (1)

Country Link
FR (1) FR2798556B1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700823B2 (en) 2003-10-02 2010-04-20 Aventis Pharma S.A. Transgenic animals exhibiting major disorders related to Alzheimer's disease
FR2860391B1 (fr) * 2003-10-02 2006-01-27 Aventis Pharma Sa Animaux transgeniques presentant les troubles majeurs lies a la maladie d'alzheimer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5586226A (en) * 1990-05-16 1996-12-17 Canon Kabushiki Kaisha Control method and device for a unicolor printer
CA2186636A1 (fr) * 1994-03-30 1995-10-12 Corinna Herrnstadt Diagnostic, therapie et modeles cellulaires et animaux concernant les affections associees aux anomalies mitochondriales
US5898094A (en) * 1996-10-21 1999-04-27 University Of South Florida Transgenic mice expressing APPK670N,M671L and a mutant presenilin transgenes

Also Published As

Publication number Publication date
FR2798556A1 (fr) 2001-03-23

Similar Documents

Publication Publication Date Title
HK1058041A1 (en) Thioflavin derivatives and their use in diagnosis and therapy of alzheimer's disease
NO981911D0 (no) Anvendelse av rhodaninderivater for fremstilling av et medikament for behandling av Alzheimer's sykdom
IL149924A0 (en) Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
PL348226A1 (en) Compounds for the antemortem diagnosis of alzheimer's disease and in vivo
EP1246632A4 (fr) Catechines et extrait de the vert destines au traitement de l'amyloidose dans la maladie d'alzheimer et d'autres amyloidoses
SI1303272T1 (sl) Derivati benzotiazola za zdravljenje alzheimerjeve bolezni in parkinsonove bolezni
AU2001249835A1 (en) Diagnosis and treatment of alzheimer's disease
EE200300216A (et) Radiofarmatseutilised ained Alzheimeri tõve diagnoosimiseks
EP0778886A4 (fr) Animal transgenique exprimant une forme familiale d'une proteine precurseur de l'amyloide humaine
EP1744762A4 (fr) Modeles transgeniques de la maladie d'alzheimer et leurs utilisations dans le traitement d'une grande variete de maladies neurodegeneratives
HK1026919A1 (en) agents for pre-symptomatic detection and therapeutic targeting of alzheimer's disease in humans
NO944844L (no) Innvendig registrering av respirasjon i et legeme
NO20002686L (no) Forbedring av Peyronies sykdom
EP1029039A4 (fr) Modele animal non transgenique de la maladie d'alzheimer
AU2003263972A8 (en) Use of an amyloid beta vaccination in combination with a selective cox-2 inhibitor for the treatment of alzheimer's disease
FR2798556B1 (fr) Nouveau modele animal de la maladie d'alzheimer presentant a la fois des plaques amyloides et des dysfonctionnements mitochondriaux
HUP9903213A1 (en) Use of 2-phenyl-1,2-benzisoselenazol-3(2h)-one for producing a pharmaceutical preparation intended for treatment of the alzheimer's disease and the medicament itself
AU2002222108A1 (en) Diagnosis and treatment of alzheimer's disease
ZA974506B (en) Medicament comprising a carnitine derivative for treating Alzheimer's disease in early-onset patients.
AU7429400A (en) Novel animal model of alzheimer disease with amyloid plaques and mitochondrial dysfunctions
AU2002212233A1 (en) Diagnostic and therapeutic use of a phosphoprotein enriched in astrocytes for alzheimer's disease and related neurodegenerative disorders
NO20016221D0 (no) Difosfatsalt av et 4"-substituert-9-deokso-9A-aza-9A- homoerytromycinderivat og farmasöytisk preparat derav
IL135808A0 (en) Radiotracers for in vivo study of acetylcholinesterase and alzheimer's disease
FI953725A0 (fi) Ornitiiniaminotransferaasi-inhibiittorien käyttö lääkeaineen valmistamiseksi Alzheimerin taudin hoitamiseksi
JPH029780Y2 (fr)

Legal Events

Date Code Title Description
CD Change of name or company name
RS Complete withdrawal
ST Notification of lapse

Effective date: 20090529