FR2786695A1 - After sun treatment containing a synergistic mixture of acetyl salicylic acid and rosemary extract - Google Patents

After sun treatment containing a synergistic mixture of acetyl salicylic acid and rosemary extract Download PDF

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FR2786695A1
FR2786695A1 FR9815394A FR9815394A FR2786695A1 FR 2786695 A1 FR2786695 A1 FR 2786695A1 FR 9815394 A FR9815394 A FR 9815394A FR 9815394 A FR9815394 A FR 9815394A FR 2786695 A1 FR2786695 A1 FR 2786695A1
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composition according
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rosemary extract
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FR2786695B1 (en
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Olivier Courtin
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Clarins SA
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Clarins SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]

Abstract

Cosmetic compositions for the skin contain acetyl salicylic acid and rosemary extract. Cosmetic compositions for the skin contain acetyl salicylic acid and rosemary extract, preferably 0.01-5 wt.% acetylsalicylic acid and 0.5-5 wt.% rosemary extract. They may be in the form of suspensions, dispersions, emulsions gels, lotions and aerosols and may contain gelling agents, silicones and vegetable extracts as well as anti-dehydrating agents, softeners, cicatrizing agents, and anti-inflammatories.

Description

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L'invention concerne une composition cosmétique destinée à l'application topique sur la peau, dans laquelle sont associés, comme principes actifs, l'acide acétylsalicylique et un extrait de romarin. La composition comprend en outre un mélange de substances classiquement utilisées comme excipient cosmétique. Elle est particulièrement appropriée à un usage "après soleil".  The invention relates to a cosmetic composition for topical application to the skin, in which acetylsalicylic acid and a rosemary extract are associated as active ingredients. The composition further comprises a mixture of substances conventionally used as a cosmetic excipient. It is particularly suitable for "after sun" use.

L'exposition prolongée de la peau au soleil provoque diverses réactions immédiates de type inflammatoire (érythème, oedème, perturbations de la microcirculation, oxydations...), une déshydratation et une fragilisation de la peau.  Prolonged exposure of the skin to the sun causes various inflammatory-type immediate reactions (erythema, edema, disturbances of the microcirculation, oxidation, etc.), dehydration and weakening of the skin.

De nombreuses recherches ont déjà abouti à la mise sur le marché de divers produits pour calmer, adoucir ou hydrater la peau, en application "après soleil".  Many researches have already resulted in the marketing of various products to calm, soften or moisturize the skin, in "after sun" application.

La Demanderesse a tiré parti des propriétés antiinflammatoires et antioxydantes connues de l'extrait de feuilles de romarin et a mis en évidence un effet synergique de l'acide acétylsalicylique sur l'action de l'extrait de romarin.  The Applicant has taken advantage of the known anti-inflammatory and antioxidant properties of the extract of rosemary leaves and has demonstrated a synergistic effect of acetylsalicylic acid on the action of rosemary extract.

L'acide acétylsalicylique est bien connu pour ses propriétés thérapeutiques analgésique, antipyrétique et anti-inflammatoire, par administration orale, mais son incorporation dans des compositions topiques pour la peau n'a pas encore été réalisée.  Acetylsalicylic acid is well known for its therapeutic analgesic, antipyretic and anti-inflammatory properties, by oral administration, but its incorporation into topical compositions for the skin has not yet been realized.

Dans la composition selon l'invention, l'acide acétylsalicylique représente, de préférence, de 0,01 à 5 % du poids total de la composition, et, l'extrait de romarin, de 0,5 à 5 % du poids total de la composition.  In the composition according to the invention, the acetylsalicylic acid preferably represents from 0.01 to 5% of the total weight of the composition, and the rosemary extract from 0.5 to 5% of the total weight of the composition. the composition.

L'acide acétylsalicylique peut être utilisé sous forme de solution alcoolique ou sous la forme d'un de ses sels choisi pour sa solubilité dans l'excipient de la composition, comme l'acétylsalicylate de calcium.  Acetylsalicylic acid may be used in the form of an alcoholic solution or in the form of a salt thereof chosen for its solubility in the excipient of the composition, such as calcium acetylsalicylate.

Ces principes actifs sont incorporés dans un mélange d'ingrédients habituellement utilisés dans les compositions cosmétiques pour en améliorer la texture et la facilité d'application. Ainsi la composition peut contenir  These active ingredients are incorporated into a mixture of ingredients usually used in cosmetic compositions to improve the texture and ease of application. So the composition can contain

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des substances de type polymères gélifiants, des silicones et des extraits végétaux.  polymeric gelling substances, silicones and plant extracts.

La composition peut se présenter sous différentes formes, en fonction de son usage potentiel, et plus particulièrement sous forme de suspension ou dispersion dans un solvant, d'émulsion de type huile dans l'eau ou eau dans l'huile, de gel, de lotion ou d'aérosol. Le mode de préparation de ces diverses formulations est connu de l'homme du métier.  The composition may be in various forms, depending on its potential use, and more particularly in the form of suspension or dispersion in a solvent, oil-in-water or water-in-oil emulsion, gel, lotion or aerosol. The mode of preparation of these various formulations is known to those skilled in the art.

La composition selon l'invention, comprend, en outre, un agent antidéshydratant et adoucissant, de préférence un extrait d'aubier de tilleul, à une concentration comprise entre 1 et 10 % du poids total de la composition.  The composition according to the invention further comprises an antidehydrating and softening agent, preferably a sapwood sapwood extract, at a concentration of between 1 and 10% of the total weight of the composition.

La composition selon l'invention peut, en outre, comprendre un extrait végétal à effet adoucissant comme le beurre de karité ou l'extrait de feuilles d'aloès.  The composition according to the invention may, in addition, comprise a plant extract with a softening effect such as shea butter or extract of aloe leaves.

La composition peut encore être additionnée d'un extrait végétal à effet cicatrisant comme l'extrait de Siegesbeckia orientalis ou l'allantoïne extraite de la grande consoude ou à effet anti-inflammatoire comme le bisabolol extrait de la camomille.  The composition may be further added with a healing effect plant extract such as Siegesbeckia orientalis extract or allantoin extracted from the great comfrey or anti-inflammatory effect such as bisabolol extracted from chamomile.

L'utilisation de ces divers extraits végétaux dérive de leur utilisation par tradition ancestrale européenne ou africaine.  The use of these various plant extracts derives from their use by ancestral European or African tradition.

La composition selon l'invention présente des qualités particulièrement remarquables : elle procure une sensation agréable et adoucissante dès le contact et un effet calmant durable sur la peau présentant les désordres associés à une exposition prolongée au soleil.  The composition according to the invention has particularly remarkable qualities: it provides a pleasant and softening sensation from the contact and a lasting soothing effect on the skin with the disorders associated with prolonged exposure to the sun.

La composition selon l'invention peut également être utilisée pour soulager toute rougeur ou irritation de la peau due à d'autres causes que l'exposition aux rayons UV.  The composition according to the invention can also be used to relieve any redness or irritation of the skin due to causes other than exposure to UV rays.

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L'exemple suivant illustre l'invention sans toutefois en limiter la portée.  The following example illustrates the invention without limiting its scope.

Exemple :
Dans les formulations présentées ci-après, on utilise des produits conventionnels d'origine commerciale. Example:
In the formulations presented hereinafter, conventional products of commercial origin are used.

Comme principes actifs on utilise, - d'une part, un extrait de romarin d'origine commerciale dont les caractéristiques sont les suivantes : - extrait de feuilles de Rosmarinus officinalis - rapport plante/extrait : 1/2 - solvant : butylène glycol - teneur en acide ursolique : > 1500 ppm
L'extrait est identifié par son profil chromatographique HPTLC (chromatographie à haute performance sur couche mince) et sa teneur en acide ursolique est quantifiée par rapport à une gamme étalon. Outre l'acide ursolique, l'extrait contient de l'acide rosmarinique et des flavonoïdes. The active ingredients used are: - a rosemary extract of commercial origin whose characteristics are as follows: - Rosmarinus officinalis leaf extract - ratio plant / extract: 1/2 - solvent: butylene glycol - content in ursolic acid:> 1500 ppm
The extract is identified by its HPLCLC (High Performance Thin Layer Chromatography) chromatographic profile and its ursolic acid content is quantified against a standard range. In addition to ursolic acid, the extract contains rosmarinic acid and flavonoids.

- d'autre part, l'acide acétylsalicylique - soit en solution dans l'alcool (1 g/6 g d'alcool) - soit sous forme d'acétylsalicylate de calcium.  - On the other hand, acetylsalicylic acid - either in solution in alcohol (1 g / 6 g of alcohol) - or in the form of calcium acetylsalicylate.

Comme agent antidéshydratant et adoucissant on utilise un extrait d'aubier de tilleul d'origine commerciale dont les caractéristiques sont les suivantes : - extrait d'aubier de tilleul - rapport plante/extrait : 1/2 - solvant : butylène glycol  As an anti-dehydrating and softening agent, a sapwood sapwood extract of commercial origin is used, the characteristics of which are as follows: - sapwood sap extract - ratio plant / extract: 1/2 - solvent: butylene glycol

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- teneur en quercétine : environ 450 ppm.  - Quercetin content: about 450 ppm.

L'extrait est identifié par son profil chromatographique HPTLC et sa teneur en quercétine est quantifiée par rapport à une gamme étalon.  The extract is identified by its HPTLC chromatographic profile and its quercetin content is quantified against a standard range.

Les formulations suivantes indiquent les pourcentages, en poids, des différents ingrédients d'une composition sous forme de lotion, de crème pour le visage, de lait pour le corps et de gel.  The following formulations indicate the percentages, by weight, of the various ingredients of a composition in the form of a lotion, a face cream, a body lotion and a gel.

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LOTION GLYCERINE...........................................................,.............................. 5.000

Figure img00050001

CITRATE TRlSOD T QUE....................................................................... 0,200 CONSERVATEUR............................................................................... 1,000 P ANTI#NOL .................................................................................. """ 0,300 EXTRAITD'ALOES.............................................................................. look EXTRAIT DE ROMARlN' """""""''''''''''''''''''''''''''''''''''''''''''''''''''''''' 1-000 EXTRAIT DE TILLEUL ..................................................-.....- ............. 1,000 ACIDE ACETYL SAUCYLIQUE....................................................... 2,000 ALCOOLETHYLIQUE......................................................................... 12,000 ALCOOL OLEIQUE POE ................................................................ 0,800 PARFUM ......................................... '"'''''''''''''''''''' ....., ,., ,.................... 0,200 EAU PU RIFlEE ................., ,............................:.....................................Q.S.P 100 GLYCERINE LOTION ................................................ ..........., .............................. 5.000
Figure img00050001

CITRATE TRlSOD T THAT .............................................. ......................... 0,200 CONSERVATIVE ....................... .................................................. ...... 1,000 P ANTI # NOL ....................................... ........................................... """0.300 EXTRACT FROM ALOES .................................................. ............................ look EXTRACT FROM ROMARlN '""""""''''''''''''''''''''''''''''''''''''''''''''" TILLEUL ................................................. .-.....- ............. 1,000 ACETYL SAUCYLIC ACID ......................... .............................. 2,000 ALCOOLETHYLIC .................. .................................................. ..... 12,000 OLEIC ALCOHOL POE ......................................... ....................... 0.800 PERFUME ......................... ................ '"''''''''''''''''''''.....,,.,, .. .................. 0,200 PU RIFlEE WATER .................,, ............................: ..................... ................ QSP 100

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CREME

Figure img00060001

GLYCERINE........................-.............-..----.-..------ #.-.--.---.- 4,000 CONSERVATEUR ................................................................................ 0,800 ALLA'NTOINE...........-#....................................................... 0.500 G{)1\.1MF. XANTIfANF......................................... 0;500 BENTONE.........-.........##.................................................. .00 TALC........##......-..-.............-....................-..-.-------- - 3,000 ALCOOI-CETYLIQUE##.##..#.........-..........-....-.----.---- 1,000 BEURRE DE KARITE ...................................................- ....................... 2,000 CETEARYL GLUCOSIDE ........... -................................................. - ----- 6,000 TRIGLY CERIDES ..................................................................................... 1,000
Figure img00060002

ISONONANOATED'ISONONYLE...................##..........-.........-# 6,000 HUILE DE SILICONE ............................................................................ 5,000 ACETYL SALICYLATE DE CALCIUM .............................................. 2,000 BISABOLOL ........................................-....... -......................................... 0,200
Figure img00060003

HUnLEDEPALME..................--...,.......--#-.#.###-#-#-- 1,000 E7tTRAIT D'riLOES............................................................................. 1,000 EXTRAIT DE ROMARIN...............................-....--#..#....#.. 1,000 EXTRAIT DE TILLEUL ....................................................................... 1,000 EXTRAIT DE SZGES13ECKIA ORMTIALIS ................................... 1,000 VITAMINE F HYDROSOLUBLE..............-.....#.....................-..... 0,200 PARFUM....................................................-.........#-###-.-# 0,500 EAU PURIFIEE ...................................................................-------- -QS lUU CREAM
Figure img00060001

GLYCERIN........................-.............-..----.-.. ------ #.-. -. --- .- 4,000 CONSERVATIVE .............................. .................................................. 0.800 ALLA'NTOINE ...........- # ................................. ...................... 0.500 G {) 1 \ .1MF. XANTIfANF ......................................... 0; 500 BENTONE .... .....-## ......... ................................. ................. .00 TALC ........ ## ......-..-.......... ...-....................-..-.-------- - 3,000 ALCOHOL-CETYLIC ##. ## .. # .........-..........-....-. ---- .---- 1,000 SHEA BUTTER .......... .........................................- ........ ............... 2,000 CETEARYL GLUCOSIDE ........... -... ............................. - ----- 6,000 TRIGLY CERIDES ............ .................................................. ....................... 1,000
Figure img00060002

ISONONANOATED'ISONONYLE ................... ## ..........-.........- # 6,000 SILICONE OIL .................................................. .......................... 5,000 ACETYL CALCIUM SALICYLATE ................... ........................... 2,000 BISABOLOL ..................... ...................-....... -...................... ................... 0.200
Figure img00060003

HUnLEDEPALME .................. - ..., .......-- # -. #. ### - # - # - 1,000 E7tTRAIT On riLOES ............................................... .............................. 1,000 ROSEMARY EXTRACT ................ ...............-....-- # .. # .... # .. 1,000 EXTRACT OF TILLEUL ............. .................................................. ........ 1,000 EXTRACT OF SZGES13ECKIA ORMTIALIS ................................... 1,000 VITAMIN F HYDROSOLUBLE ..............-..... # .....................-..... 0.200 PERFUME ................................................ ....-......... # - ### -.- # 0,500 PURIFIED WATER ........................ ...........................................------- - -QS lUU

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LAIT

Figure img00070001

SUCCINA1'E D'OCTYLE...................................................................... 4,000 HUILE DE VASELINE......................................................................... 5,000 HUEL-EDEILICONE ....................................................................... 1,000 BEURRE DE KARITE........................................................................... 2,000 MONOMYRISTATE DE GLYCEROL ................................................. 5,000
Figure img00070002

ISONON.IOATE b'ISONONYLE..........~....,................,...................,. 3,000 C12-15 ALKYL BENZOATE ................................................................ 8,000 BEHENATE DE GLYCEROL.........,....,...,................,........................... 1,000 GLYCERINE..................................,.,...................................................., 5,000 ACIDE ACETYL SALICYLIQUE........................................................ 1,000
Figure img00070003

ALCOOL ETHYLIQUE .... .................................................................... 6,000 EDTADISODIQUB............................................................................... 0,100 CONSERVATEUR................................................................................ 1,000 GOMME XAN1"HANE .......................................................................n. 0,100 CARBOXY METHYL CELLULOSE..............,........,............................ 0,200 POTASSIUM CETYL PHOSPHATE ...........,...,......,..,.......................... 2,000 EXTRAIT D'ALOES................,....................,...................,.................... 2,000
Figure img00070004

EXTRAIT DE ROMA.R1N ........................................"........................... 1,000 EXTRAIT DE TILLEUL 1.000 PARFUM .............................................................................................. 0,500
Figure img00070005

E'A U PU R1FlEE ....................................................................................Q.SJ 100 MILK
Figure img00070001

OCTYLE SUCCINION ............................................ .......................... 4,000 VASELINE OIL .................... .................................................. ... 5,000 HUEL-EDEILICONE ........................................... ............................ 1,000 SHEA BUTTER .................. .................................................. ....... 2,000 MONOMYRISTATE OF GLYCEROL ....................................... .......... 5,000
Figure img00070002

ISONON.IOATE b'ISONONYLE .......... ~ ...., ................, ........... ......... 3,000 C12-15 ALKYL BENZOATE ............................................ .................... 8,000 GLYCEROL BEHENATE ........., ...., ..., ....... ........., ........................... 1,000 GLYCERINE ........... .......................,., ........................ ............................, 5,000 ACETYL SALICYLIC ACID ................. ....................................... 1,000
Figure img00070003

ETHYL ALCOHOL .... ............................................ ........................ 6,000 EDTADISODIQUB ........................ .................................................. ..... 0,100 CONSERVATIVE ........................................... ..................................... 1,000 GUM XAN1 "HANE ........ .................................................. ............. No. 0.100 CARBOXY METHYL CELLULOSE .............., ........, ....... ..................... 0,200 POTASSIUM CETYL PHOSPHATE ..........., ..., ......, .. , .......................... 2,000 EXTRACT OF ALOES ................,. ..................., ................... .......... .......... 2,000
Figure img00070004

EXTRACT FROM ROMA.R1N ........................................ ".... ....................... 1,000 EXTRACT OF TILLEUL 1.000 PERFUME ..................... .................................................. ....................... 0,500
Figure img00070005

R1FlEE E'A U PU ............................................ ........................................ Q.SJ 100

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GEL EDTA DISODIQUE.............................................................................. 0,100

Figure img00080001

PROPYLENE GLYCOL ........................................................................ 2,000 CONSERVATEUR 0.700 GOMME XANTHANE........................................................................... 0.150 CARBOXY METHYL CELLULOSE.................................................... 0,250 EXTRAIT D'ALOES............................................................,................. 4.000 EXTRAIT DE ROMARIN 1.000
Figure img00080002

EXTRAIT DE TILLEUL ..................................................,................... 1,000 BISABOLOL,.,................................................................~~...~~.~.... ~ ...~.. 1,onO PANTHENOL......................................................................................... 0,100 ACETATE DE TOCOPHEROL.................................................................. 0,100 PALMITATE DE VITAMINE. A ............... ............ 0,100
Figure img00080003

ACIDE ACETYLSALICYLIQUE....................##......-.....-#.--- 1.000 PARFUM ............................................................................................... 0,300 HT ITT .F. ]")'1= 'R [(,rN HYDROGENEE ..................................................... 1.200 ALCOOL ETHYLIQUE 6,000 EAU PURIFIEE ,..............................................,............~.~......................Q.s.P 100EDOD DISODIUM GEL ............................................... ............................... 0,100
Figure img00080001

PROPYLENE GLYCOL ................................................ ........................ 2,000 CONSERVATIVE 0.700 XANTHANE GUM ..................... .................................................. .... 0.150 CARBOXY METHYL CELLULOSE .......................................... .......... 0,250 ALOE EXTRACT ................................... ........................., ................. 4.000 ROSEMARY EXTRACT 1.000
Figure img00080002

EXTRACT OF TILLEUL ............................................... ..., ................... 1,000 BISABOLOL,., ...................... .......................................... ... ~~ ~~. ~ .... ~ ... ~ .. 1, onO PANTHENOL .................................. .................................................. ..... 0.100 TOCOPHEROL ACETATE ......................................... ......................... 0,100 PALMITATE OF VITAMIN. A ............... ............ 0.100
Figure img00080003

ACETYLSALICYLIC ACID .................... ## ......-.....- # .--- 1.000 PERFUME ...... .................................................. ....................................... 0.300 HT ITT .F. ] ") '1 =' R [(, rN HYDROGENEE ..................................... ................ 1.200 ETHYL ALCOHOL 6,000 PURIFIED WATER, ........................... ................... ............ ~. ~ ............... ....... QsP 100

Claims (10)

REVENDICATIONS 1.- Composition cosmétique pour la peau, caractérisée en ce qu'elle comprend, comme principes actifs, de l'acide acétylsalicylique et de l'extrait de romarin. 1.- Cosmetic composition for the skin, characterized in that it comprises, as active ingredients, acetylsalicylic acid and rosemary extract. 2. - Composition selon la revendication 1, caractérisée en ce que l'acide acétylsalicylique représente de 0,01 à 5 % du poids total de la composition.  2. - Composition according to claim 1, characterized in that the acetylsalicylic acid is from 0.01 to 5% of the total weight of the composition. 3.- Composition selon la revendication 1 ou 2, caractérisée en ce que l'extrait de romarin représente de 0,5 à 5 % du poids total de la composition.  3. Composition according to claim 1 or 2, characterized in that the rosemary extract represents from 0.5 to 5% of the total weight of the composition. 4. - Composition selon l'une quelconque des revendications 1 à 3, caractérisée en ce qu'elle contient, en outre, des ingrédients habituellement utilisés dans les compostions cosmétiques, de type polymères gélifiants, silicones, extraits végétaux.  4. - Composition according to any one of claims 1 to 3, characterized in that it further contains ingredients usually used in cosmetic compositions, gelling polymer type, silicones, plant extracts. 5. - Composition selon l'une quelconque des revendications 1 à 4, caractérisée en ce qu'elle se présente sous forme d'une suspension ou d'une dispersion dans un solvant, d'une émulsion de type huile dans l'eau ou eau dans l'huile, d'un gel, d'une lotion, ou d'un aérosol.  5. - Composition according to any one of claims 1 to 4, characterized in that it is in the form of a suspension or a dispersion in a solvent, an oil-in-water type emulsion or water in oil, gel, lotion, or aerosol. 6. - Composition selon l'une quelconque des revendications 1 à 5, caractérisée en ce qu'elle contient, en outre, un agent antidéshydratant et adoucissant.  6. - Composition according to any one of claims 1 to 5, characterized in that it further contains an anti-dehydrating and softening agent. 7. - Composition selon la revendications 6, caractérisée en ce que l'agent antidéshydratant et adoucissarit est un extrait d'aubier de tilleul et qu'il représente de 1 à 10 % du poids total de la composition.  7. - Composition according to claim 6, characterized in that the anti-dehydrating and softening agent is a sapwood sapwood extract and it represents from 1 to 10% of the total weight of the composition. 8. - Composition selon l'une quelconque des revendications 1 à 7 caractérisée en ce qu'elle contient, en outre, un extrait végétal adoucissant du type beurre de karité ou extrait de feuilles d'aloès.  8. - Composition according to any one of claims 1 to 7 characterized in that it further contains a softening plant extract shea butter type or extracted from aloe leaves. 9. - Composition selon l'une quelconque des revendications 1 à 8 caractérisée en ce qu'elle contient, en outre, un extrait végétal à effet cicatrisant du type extrait de Siegesbeckia orientalis ou allantoïne extraite de grande consoude.  9. - Composition according to any one of claims 1 to 8 characterized in that it further contains a plant extract healing effect of the type extracted from Siegesbeckia orientalis or allantoin extracted from large comfrey. <Desc/Clms Page number 10> <Desc / Clms Page number 10> 10. - Composition selon l'une quelconque des revendications 1 à 9 caractérisée en ce qu'elle contient un extrait végétal à effet anti-inflammatoire du type bisabolol, extrait de camomille. 10. - Composition according to any one of claims 1 to 9 characterized in that it contains a plant extract with anti-inflammatory effect of bisabolol type, camomile extract.
FR9815394A 1998-12-07 1998-12-07 COSMETIC COMPOSITION BASED ON ACETYLSALICYLIC ACID AND Rosemary Extract Expired - Fee Related FR2786695B1 (en)

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FR9815394A FR2786695B1 (en) 1998-12-07 1998-12-07 COSMETIC COMPOSITION BASED ON ACETYLSALICYLIC ACID AND Rosemary Extract

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FR9815394A FR2786695B1 (en) 1998-12-07 1998-12-07 COSMETIC COMPOSITION BASED ON ACETYLSALICYLIC ACID AND Rosemary Extract

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CN106309457B (en) * 2016-11-03 2018-11-27 福州大学 A kind of ursolic acid-Aspirin Conjugate is preparing the application in liver protecting drug

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015590A1 (en) * 1989-06-22 1990-12-27 Rosen Steven E Topical agent and method for the treatment of pseudofolliculitis barbae
WO1995003779A1 (en) * 1993-07-30 1995-02-09 Unilever Plc Cosmetic composition containing hydroxyacids
EP0784975A1 (en) * 1995-12-26 1997-07-23 Teikoku Seiyaku Kabushiki Kaisha Use of acetylsalicylic acid in the manufacture of a drug for the treatment of skin injuries
FR2751878A1 (en) * 1996-07-30 1998-02-06 Oreal USE IN A COMPOSITION OF AN EXTRACT OF AT LEAST ONE LABIEE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015590A1 (en) * 1989-06-22 1990-12-27 Rosen Steven E Topical agent and method for the treatment of pseudofolliculitis barbae
WO1995003779A1 (en) * 1993-07-30 1995-02-09 Unilever Plc Cosmetic composition containing hydroxyacids
EP0784975A1 (en) * 1995-12-26 1997-07-23 Teikoku Seiyaku Kabushiki Kaisha Use of acetylsalicylic acid in the manufacture of a drug for the treatment of skin injuries
FR2751878A1 (en) * 1996-07-30 1998-02-06 Oreal USE IN A COMPOSITION OF AN EXTRACT OF AT LEAST ONE LABIEE

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