FR2772764B1 - NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS - Google Patents

NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS

Info

Publication number
FR2772764B1
FR2772764B1 FR9716335A FR9716335A FR2772764B1 FR 2772764 B1 FR2772764 B1 FR 2772764B1 FR 9716335 A FR9716335 A FR 9716335A FR 9716335 A FR9716335 A FR 9716335A FR 2772764 B1 FR2772764 B1 FR 2772764B1
Authority
FR
France
Prior art keywords
preparation
farnesyle
medicaments
novel
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9716335A
Other languages
French (fr)
Other versions
FR2772764A1 (en
Inventor
Norbert Dereu
Patrick Mailliet
Thompson Fabienne Sounigo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9716335A priority Critical patent/FR2772764B1/en
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to CA002315144A priority patent/CA2315144A1/en
Priority to AU17675/99A priority patent/AU1767599A/en
Priority to JP2000526514A priority patent/JP2001527078A/en
Priority to EP98962528A priority patent/EP1042329A1/en
Priority to PCT/FR1998/002804 priority patent/WO1999033834A1/en
Priority to ZA9811787A priority patent/ZA9811787B/en
Publication of FR2772764A1 publication Critical patent/FR2772764A1/en
Application granted granted Critical
Publication of FR2772764B1 publication Critical patent/FR2772764B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9716335A 1997-12-23 1997-12-23 NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS Expired - Fee Related FR2772764B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9716335A FR2772764B1 (en) 1997-12-23 1997-12-23 NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS
AU17675/99A AU1767599A (en) 1997-12-23 1998-12-21 Novel farnesyl transferase inhibitors, preparation, pharmaceutical compositions containing them and use for preparing medicines
JP2000526514A JP2001527078A (en) 1997-12-23 1998-12-21 Novel farnesyltransferase inhibitors, their preparation, pharmaceutical compositions containing them and their use for the preparation of medicaments
EP98962528A EP1042329A1 (en) 1997-12-23 1998-12-21 Novel farnesyl transferase inhibitors, preparation, pharmaceutical, compositions containing them and use for preparing medicines
CA002315144A CA2315144A1 (en) 1997-12-23 1998-12-21 Novel farnesyl transferase inhibitors, preparation, pharmaceutical compositions containing them and use for preparing medicines
PCT/FR1998/002804 WO1999033834A1 (en) 1997-12-23 1998-12-21 Novel farnesyl transferase inhibitors, preparation, pharmaceutical compositions containing them and use for preparing medicines
ZA9811787A ZA9811787B (en) 1997-12-23 1998-12-22 Novel farnesyl transferase inhibitors, their preparation, pharmaceutical compositions which contain them and their use for the preparation of medicaments.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9716335A FR2772764B1 (en) 1997-12-23 1997-12-23 NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS

Publications (2)

Publication Number Publication Date
FR2772764A1 FR2772764A1 (en) 1999-06-25
FR2772764B1 true FR2772764B1 (en) 2000-01-14

Family

ID=9514982

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9716335A Expired - Fee Related FR2772764B1 (en) 1997-12-23 1997-12-23 NOVEL FARNESYLE TRANSFERASE INHIBITORS, THEIR PREPARATION, THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE IN THE PREPARATION OF MEDICAMENTS

Country Status (2)

Country Link
FR (1) FR2772764B1 (en)
ZA (1) ZA9811787B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796641B1 (en) 1999-07-22 2001-09-21 Aventis Pharma Sa NOVEL PROCESS FOR THE PREPARATION OF BENZOPERHYDROISOINDOLE COMPOUNDS
AU2001235496A1 (en) * 2000-02-29 2001-09-12 Janssen Pharmaceutica N.V. Farnesyl protein transferase inhibitor combinations with anti-tumor alkylating agents
US20030125326A1 (en) * 2000-02-29 2003-07-03 Rybak Mary Ellen Margaret Farnesyl protein transferase inhibitor combinations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2736641B1 (en) * 1995-07-10 1997-08-22 Rhone Poulenc Rorer Sa NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
ZA9811787B (en) 1999-06-29
FR2772764A1 (en) 1999-06-25

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Legal Events

Date Code Title Description
ST Notification of lapse